Comparison of the Pressure Support Mode of Anesthesic Respiratory and Resuscitation Ventilators by V. A. Pyzhov, K. N. Khrapov

“…However, in terms of the response rate of the trigger system, modern anesthesia machines (GE Avance S/2, GE Caretation 650, and GE Aisys CS2) are not significantly inferior to traditional ventilators, their trigger delay time is about 100 ms. …”
Get full text

L-shaped association between dietary niacin intake and chronic kidney disease among adults in the USA: a cross-sectional study by Qishu Li, Wei Lan

“…CKD was determined by an estimated glomerular filtration rate (eGFR) (<60 ml/min/1.73 m2) or a urinary albumin-to-creatinine ratio (ACR) (≥30mg/g). …”
Get full text

Comparison of Different Ultrasound Protocols in Patients with Inflammatory Polyneuropathies with Practical Insights by Evelina Grusauskiene, Agne Smigelskyte, Erisela Qerama, Daiva Rastenyte

“…When the adjusted EAN/PNS protocol was applied, the detection rate rose to 100%, with a sensitivity of 100%. Both the adjusted BUS/NUP and UPSS protocols demonstrated a specificity of 90% in diagnosing CIDP. …”
Get full text

Evaluation of Cerebrospinal Fluid Pressure by a Formula and Its Role in the Pathogenesis of Glaucoma by Laura Landi, Federica Casciaro, Serena Telani, Carlo E. Traverso, Alon Harris, Alice C. Verticchio Vercellin, Lauren Saint, Michele Iester

“…Weight and height were measured to calculate body mass index (BMI), along with blood pressure, heart rate, visual acuity, and IOP. Biometrics exam, corneal pachymetry, peripapillary retinal nerve fiber layer (RNFL) thickness, and macular thickness were assessed. …”
Get full text

Experimental study on nonlinear hygroscopic and strength behavior of mudstone under coupled temperature and humidity conditions for underground engineering by Weisheng Zhao, Lijun Han, Shuai Yan, Wei He

“…The results indicated that the equilibrium water content (EWC) exhibited a three-stage growth pattern with increasing humidity: rapid growth (0‒20% RH), slow growth (20‒60% RH), and accelerated growth (60‒100% RH), whereas it decreased with increasing temperature, although the rate of decrease slowed progressively. …”
Get full text

Elderly patients undergoing laparoscopic radical cystectomy benefit from dynamic D-dimer measurement in combination with vascular ultrasonography: reduction of VTE risk and improve... by Wenbo Gao, Haihong Ye, Yangkai Xu

“…The incidence of VTE event, major postoperative complications, major bleeding rate, and evaluation of activities of daily living within 30 days postoperatively were compared.ResultsThe preoperative and intraoperative parameters were similar between the two groups. …”
Get full text

Impact of Caspase3/GSDME-Mediated Pyroptosis on Tumor Immune Microenvironment and Clinical Prognosis Across Multiple Cancers by Huang Y, Liu J, Lin C, Zhu Q, Wu L

“…Its uncontrolled growth pattern and metastasis characteristics are the fundamental reasons for the high mortality rate of cancer and its current incurability. …”
Get full text

IMPAIRED REGULATORY MECHANISMS OF THE mTOR SIGNALING PATHWAY IN OSTEOARTHROSIS by Elena Vasilyevna Chetina, E A Bratygina, E M Zaitseva, E P Sharapova, A L Alekseyeva, N V Demin, S A Makarov

“…Objective: to study the pattern of impaired regulatory mechanisms of the mammalian target of rapamycin (TOR) signaling pathway, by monitoring gene expression in the blood of patients with osteoarthrosis (OA) at different stages of the disease. …”
Get full text

Etiology, antibiotic susceptibility and prognostic factors of pediatric community-acquired sepsis in Addis Ababa, Ethiopia by Abel Abera Negash, Daniel Asrat, Workeabeba Abebe, Tewodros Hailemariam, Andualem Wubete, Abraham Aseffa, Mario Vaneechoutte

“…We sought to determine the etiology, role of Streptococcus pneumoniae, antibiotic susceptibility pattern, and prognostic factors in children with CAS in Addis Ababa, Ethiopia. …”
Get full text

Nonlinear association between AST/ALT ratio and 28-day all-cause mortality following ICU admission in critically ill cirrhotic patients: a retrospective cohort study by Zhigang Xu, Baohong Xu

“…Results The study involved 2,090 critically ill liver cirrhosis patients, averaging 59.1 years old, with 65% male and a 28-day post-ICU admission mortality rate of 29%. The AST/ALT ratio was linked to mortality risk (adjusted odds ratio (OR) 1.1, 95% confidence interval (CI) 1.0–1.2; p = 0.015), showing a nonlinear pattern with a critical point at 3.6. …”
Get full text

Advances in application of ultrasound in diagnosis of diabetic nephropathy by GUO Juan, YANG Zhifang, JI Ri

“…As the global incidence rate of diabetes continues to rise, the clinical diagnosis and treatment of DN have become increasingly critical. …”
Get full text

Hyper-induction of IL-6 after TLR1/2 stimulation in calves with bovine respiratory disease. by Cian Reid, John Donlon, Aude Remot, Emer Kennedy, Giovanna De Matteis, Cliona O'Farrelly, Conor McAloon, Kieran G Meade

“…ROC analysis identified this induced IL-6 response to TLR1/2 stimulation as a potential diagnostic for BRD with a 74% true positive and 5% false positive detection rate for an IL-6 concentration >1780pg/mL. Overall, these results show altered immune responses specifically upon TLR1/2 activation is associated with BRD pathology which may contribute to disease progression. …”
Get full text

Genetic and clinical characteristics of catecholaminergic polymorphic ventricular tachycardia in a Taiwanese nationwide cohort by Grace Chia-Yen Hsu, Mei-Hwan Wu, Jing-Yuan Chuang, Shuenn-Nan Chiu, Ming-Tai Lin, Ling-Ping Lai, Shih-Fan Sherri Yeh, Sheng-Fu Liu, Ting-Tse Lin, Fu-Tien Chiang, Jyh-Ming Jimmy Juang

“…Among the 29 Taiwanese patients with CPVT-related gene mutations, 55% had RYR2 mutations, a rate similar to other ethnicities. Three out of 12 RYR2 variants were unreported. …”
Get full text

Anthropogenic Activities Dominate Vegetation Improvement in Arid Areas of China by Yu Guo, Xinwei Wang, Hongying Cao, Qin Peng, Yunshe Dong, Yunchun Qi, Jian Liu, Ning Lv, Feihu Yin, Xiujin Yuan, Mei Zeng

“…The results indicated that (1) overall vegetation cover was low (averaged peak FVC = 0.191), showing a spatial pattern of higher values in the northwest and lower values in the southeast; high FVC values were primarily observed in mountainous areas and river corridors; (2) the annual peak FVC increased significantly at a rate of 0.0508 yr⁻¹, with 33.72% of the region showing significant improvements and 5.49% degradation; (3) the spatial pattern of FVC was shaped by the distribution of land use types (59.46%), while the temporal dynamics of FVC were driven by land use changes (16.37%) and the land use intensity (37.56%); (4) both the spatial pattern and the temporal dynamics were limited by the environmental conditions. …”
Get full text

Prevalence and sequence of chronic conditions in older people with dementia: a multi-province, population-based cohort study by Susan E. Bronskill, Azmina Artani, Laura C. Maclagan, Xuesong Wang, Hannah Chung, J. Michael Paterson, Andrea Gruneir, Karen A. Phillips, Rasaq Ojasanya, Xibiao Ye, Kayla McLean, Fernanda Ewerling, Claire Godard-Sebillotte, Victoria Massamba, Louis Rochette, Isabelle Vedel, Larry Shaver, Catherine Pelletier, Colleen J. Maxwell

“…MethodsWe analyzed data from the 2019 Canadian Community Health Survey on the self-rated ability of adults and youth (N = 60 643; 12+ years) to cope with unexpected or difficult problems and day-to-day demands along with three PMH outcomes: selfrated mental health (SRMH), happiness and life satisfaction. …”
Get full text

Dynamics of cerebral blood flow following sertraline treatment in adolescent depression by Wenyu Ren, Wenyu Ren, Xiao Liu, Zhiwei Zhang, Xiaoqin Zhang, Wei Wu, Xingyu Wang, Zhihui Yu, Chuan Liu, Renqiang Yu

“…Furthermore, Pearson correlation analysis was employed to examine associations between changes in regional CBF and clinical improvement, as measured by changes in the 17-item Hamilton Depression Rating Scale (HAMD-17) scores.ResultsAt baseline, adolescents with depression exhibited increased CBF in the posterior cuneus and decreased CBF in the middle temporal gyrus (MTG), right middle orbitofrontal gyrus, and the left middle frontal gyrus (MFG), compared to healthy controls. …”
Get full text

Real-Time, Risk-Based Clinical Trial Quality Management in China: Development of a Digital Monitoring Platform by Min Jiang, Shuhua Zhao, Yun Mei, Zhiying Fu, Yannan Yuan, Jie Ai, Yuan Sheng, Ying Gong, Jingjing Chen

“…Quality findings from the early-stage, interim-stage, and conclusion-stage QC rounds of clinical trials were rated by using 3 severity grades (minor, major, or critical) and classified into 5 categories (with 4 taxonomy levels under each category). …”
Get full text

Criminal legal penalties, substance use, and overdose: a concept mapping study examining Colorado’s criminal legal penalties by Katherine LeMasters, Samantha K. Nall, Cole Jurecka, Betsy Craft, Paul J. Christine, Ryan Goodman, Jessie Henderson, Robert Haywood-James, Angela Williams, Grace Wittner, Joshua A. Barocas

“…Participants — recruited from community-based organizations — identified, rated, sorted, and categorized factors affecting criminal legal involvement, substance use, and/or overdose in their community. …”
Get full text

Functioning in patients with major depression treated with duloxetine or a selective serotonin reuptake inhibitor in East Asia by Novick D, Montgomery W, Haro JM, Moneta MV, Zhu G, Yue L, Hong J, Duenas H, Brugnoli R

“…Depression severity was assessed using the 16-item Quick Inventory of Depressive Symptomatology-Self Report. PPS were rated using the modified Somatic Symptom Inventory. …”
Get full text

The Effectiveness of Fiscal Decentralization in Alleviating Poverty from An Sharia Economic Perspective in Kebumen, Indonesia by Muyassarah Muyassarah, Abdul Ghofur, Ali Mutadho, Maizatul Saadiah binti Mohamad, Mansur Mansur

“…The research objective is to determine the effectiveness of fiscal independence in poverty alleviation based on economic principles, efficiency, effectiveness, independence, and the pattern of regional and central relations. This research uses a qualitative approach, secondary data from the 2019-2021 APBD, and interviews by looking at the economic formula, efficiency, and effectiveness, as well as the independence of regional financial management and analysis techniques with an Islamic economic approach.Kebumen's financial management has not been able to reduce the poverty rate because of its low self-support because it still needs a budget injection from the province/central. …”
Get full text