Barriers and facilitators to implementing a task-sharing mental health intervention for Sickle Cell Disease populations in low- and middle-income countries: a qualitative analysis... by John Patena, Leah Elster, Tania Hameed, Sumedha Kulkarni, Alden Yuanhong Lai, Annika C. Sweetland, Joyce Gyamfi, Temitope Ojo, Angela Odoms-Young, Charmaine Royal, Emmanuel Peprah

“…BackgroundPeople living with Sickle Cell Disease (SCD) experience higher rates of common mental disorders (CMD). There is an alarming treatment gap in the provision of adequate mental health services for CMDs in low- and middle-income countries (LMIC). …”
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Multicenter study correlating molecular characteristics and clinical outcomes of cancer cases with patient-derived organoids by Paloma Navarro, Tatiana P. Grazioso, Arantzazu Barquín, Maria Barba, Mónica Yagüe, Carlos Millán, Irene López, Elena Sevillano, Miguel Quiralte, Paloma Fernández, Diego Losada, Eduardo Caleiras, Julia Calzas, Beatriz Jiménez, Sergio Ruiz-Llorente, Juan Justo, Félix Guerrero, Vital Hevia, Raquel Martín, Francisco José Pérez-Rodriguez, Julia Tejerina, Mario Prieto, Paula Comune, Juan Francisco Rodriguez-Moreno, Jesús García-Donás

“…PDOs reproduced pathological and immunohistochemical patterns of source tumors, with pathogenic variants confirmed in 84% (21/25). …”
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Thermo-hydro-mechanical coupling mechanisms and sensitivity analysis of abandoned mine thermal energy storage systems by Liyuan LIU, Yaohui LI, Tao WANG, Tongbin ZHAO, Qiang KOU, Zerui MI, Le ZHANG

“…A three-dimensional thermo-hydro-mechanical (THM) coupled numerical model is developed to calculate the coupled effects over a decade of system operation and analyze heat transfer processes along with stress variation patterns in the roadway’s surrounding rock. Results indicate that the MTES system effectively utilizes geothermal environments for high-efficiency storage of waste heat, achieving a residual temperature of 35.5 ℃ (44.4% retention rate) during the first year following the injection of 80 ℃ water, with winter extraction temperatures progressively increasing annually. …”
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Spatio-Temporal Characteristics and Driving Forces of Landscape Ecological Risks in Highly Urbanized Areas: A Case Study of Suzhou City by Lingyue LU, Dawei SHAO, Dianming WU

“…However, relatively little attention has been given to urbanized areas characterized by high rates of population growth and land development. …”
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A longitudinal qualitative study of clinical nurses caring for hospitalized adults during the first fifteen months of COVID-19: lessons in professional survival and leadership by Elizabeth M. Norman, Mildred Ortu Kowalski, Roxanne Sabatini, Carol S. Jones, Wendy Silverstein

“…The research team wondered how a large American suburban medical center staff was dealing with this virus and if there were changing patterns in the experiences and thoughts of clinical nurses as the virus evolved in 2020–2021. …”
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Past Expansion and Future Prediction of Land Use and Land Cover of Sofia City by D. Pavlov, D. Pavlov, L. L. Vitanova, D. Petrova-Antonova

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Development technologies and models of different types of gas reservoirs in Ordos Basin, NW China by Ailin JIA, Dewei MENG, Guoting WANG, Guang JI, Zhi GUO, Naichao FENG, Ruohan LIU, Suqi HUANG, Shuai ZHENG, Tong XU

“…Four key directions of future research and technological breakthroughs are proposed: (1) Utilizing dual-porosity (fracture-matrix) modeling techniques in low-permeability carbonate reservoirs to delineate the volume and distribution of remaining gas in secondary pay zones, supporting well pattern optimization and production enhancement of existing wells. (2) Integrating well-log and seismic data to characterize reservoir spatial distribution of successive strata, enhancing drilling success rates in low-permeability sandstone reservoirs. (3) Utilizing the advantages of horizontal wells to penetrate effective reservoirs laterally, achieving meter-scale quantification of small-scale single sand bodies in tight gas reservoirs, and applying high-resolution 3D geological models to clarify the distribution of remaining gas and guide well placement optimization. (4) Further strengthening the evaluation of deep coal-rock gas in terms of resource potential, well type and pattern, reservoir stimulation, single-well performance, and economic viability.…”
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Specialized insectivores drive differences in avian community composition between primary and secondary forest in Central Africa by Eleanor M. Barrie, Eleanor M. Barrie, Billi A. Krochuk, Billi A. Krochuk, Crinan Jarrett, Crinan Jarrett, Crinan Jarrett, Diogo F. Ferreira, Diogo F. Ferreira, Diogo F. Ferreira, Patricia F. Rodrigues, Patricia F. Rodrigues, Patricia F. Rodrigues, Patricia F. Rodrigues, Susana Lin Mufumu, Susana Lin Mufumu, Silvestre Esteban Malanza, Silvestre Esteban Malanza, Agustin Ebana Nsue Akele, Agustin Ebana Nsue Akele, Cayetano Ebana Ebana Alene, Cayetano Ebana Ebana Alene, Kristin E. Brzeski, Kristin E. Brzeski, Jacob. C. Cooper, Jacob. C. Cooper, Jacob. C. Cooper, Jared D. Wolfe, Jared D. Wolfe, Luke L. Powell, Luke L. Powell, Luke L. Powell, Luke L. Powell

“…Notably, few species disappeared entirely in secondary forest (unlike patterns seen in the Neotropics); rather, capture rates of 12 of 30 species (40%) were significantly reduced relative to primary forest. …”
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Global burden trends and future predictions of ischemic heart disease attributable to air pollution in people aged 60 years and older, 1990–2021 by Yuanqin Zhao, Yuanqin Zhao, Lihui Liu, Lihui Liu, Wei Fan, Wei Fan, Man Qi, Man Qi, Bin Liao, Bin Liao

“…Therefore, it is of utmost significance to investigate the impact of AP on IHD burden, especially on vulnerable populations such as older individuals.MethodologyGlobal Burden of Disease (GBD) Study 2021 data was used to analyze and quantify contemporary global burden of IHD in individuals aged 60 and above due to AP and for trends for the time period between 1990 and 2021 using disease burden indicators such as deaths, DALYs, YLDs, YLLs and corresponding age-standardized rates (ASRs). Specifically, we are in patterns of disease burden of IHD in various subgroups stratified by age, sex, Sociodemographic Index (SDI), and GBD regions and countries. …”
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Burden of six common sexually transmitted infections groups in North Africa and Middle East Region from 1990 to 2021: A systematic analysis of global burden of diseases by Amirhossein Shahsavand, Leonardo Oliveira Reis, Ali Golestani, Alireza Namazi Shabestari, Ziba Aghsaeifard, Ozra Tabatabaei-Malazy, Iman Menbari Oskouie, Bagher Larijani, Seyed Mohammad Kazem Aghamir

“…Both age-standardized rates (ASRs) and total numbers were evaluated across 21 NAME countries, with breakdowns by sex, age, and sociodemographic index (SDI). …”
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Postoperative liver dysfunction in gastric cancer patients following early enhanced nutritional protocols: a retrospective observational study by Kazuo Kobayashi, Satoshi Ida, Masanari Tsuji, Arisa Nawa, Takeshi Aoyama, Takashi Yokokawa, Yoshikazu Tateai, Shuichi Watabe, Hisanori Shimizu, Souya Nunobe, Masakazu Yamaguchi

“…AST and ALT levels showed a biphasic pattern, with two distinct peaks observed on POD 1 and POD 7. …”
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Dietary inflammatory index and mortality in middle-aged and elderly patients with metabolic syndrome by Xiangmei Li, Lei Liu, Xing Li, Long Yang, Li Men

“…Promoting an anti-inflammatory dietary pattern may be a cost-effective, non-pharmacologic approach to reducing the risk of cardiometabolic mortality in an aging population with a high cardiometabolic burden.…”
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Rapid biphasic decay of intact and defective HIV DNA reservoir during acute treated HIV disease by Alton Barbehenn, Lei Shi, Junzhe Shao, Rebecca Hoh, Heather M. Hartig, Vivian Pae, Sannidhi Sarvadhavabhatla, Sophia Donaire, Caroline Sheikhzadeh, Jeffrey Milush, Gregory M. Laird, Mignot Mathias, Kristen Ritter, Michael J. Peluso, Jeffrey Martin, Frederick Hecht, Christopher Pilcher, Stephanie E. Cohen, Susan Buchbinder, Diane Havlir, Monica Gandhi, Timothy J. Henrich, Hiroyu Hatano, Jingshen Wang, Steven G. Deeks, Sulggi A. Lee

“…Defective DNA had a similar biphasic pattern, but data were more variable. Predicted intact and defective decay rates were faster for PLWH with earlier timing of ART initiation, higher initial CD4 + T cell count, and lower pre-ART viral load. …”
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Release Behavior and Bioaccumulation Characteristics of Organophosphate Esters from Plastics in Marine Aquaculture by Zhi YANG, Dongni LIU, Shengnan HUANG, Xuetian DAI, Wei QIAN, Xiaoshan ZHU

“…Chlorinated OPEs exhibited the highest dissolution rates, with TCEP showing a dissolution rate of 40.6%. …”
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Decentralized Immunization Monitoring: Lessons Learnt from a Pilot Implementation in Kumbotso LGA, Kano State, Nigeria by Adam Attahiru, Yahaya Mohammed, Fiyidi Mikailu, Hyelshilni Waziri, Ndadilnasiya Endie Waziri, Mustapha Tukur, Bashir Sunusi, Mohammed Nasir Mahmoud, Nancy Vollmer, William Vargas, Yusuf Yusufari, Gustavo Corrêa, Heidi W. Reynolds, Teemar Fisseha, Talatu Buba Bello, Moreen Kamateeka, Adefisoye Oluwaseun Adewole, Musa Bello, Imam Wada Bello, Sulaiman Etamesor, Joseph J. Valadez, Patrick Nguku

“…Univariate and bivariate analyses were performed to show patterns and relations across variables. Results: Out of 418 caregivers surveyed, 98.1% were female. …”
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A retrospective analysis of 6942 amniocentesis cases by Qingsha An, Yuxiao Huang, Feifei Yu, Yilun Tao, Juan Li, Xiaoze Li

“…The analysis encompassed the detection rate of chromosomal abnormalities via amniocentesis, the proportion and positive predictive value (PPV) of each indication group, the distribution of maternal age and gestational age, and the characteristic patterns of confirmed diagnostic findings. …”
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Long-term outcomes of dupilumab therapy in severe asthma: A retrospective, multicenter, real-world study by Carlo Mümmler, MD, Alexandra Lenoir, MD, Jeremias Götschke, MD, Michael Gerckens, MD, Merle Kaiser, MD, Moritz Kayser, MD, Nora Drick, MD, Hendrik Suhling, MD, Leonie Biener, MD, Carmen Pizarro, MD, Dirk Skowasch, MD, Nikolaus Kneidinger, MD, PhD, Jürgen Behr, MD, Katrin Milger, MD

“…Real-world data on the continuation and cessation patterns of dupilumab and long-term treatment efficacy are scarce. …”
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Real-World Evidence of Safety and Efficacy of Carboplatin plus Nanoparticle Albumin-Bound Paclitaxel in Patients with Advanced Non-Small-Cell Lung Cancer and Preexisting Interstiti... by Tomoyuki Araya, Toshiyuki Kita, Tsukasa Ueda, Nanao Terada, Tamami Sakai, Kenta Yamamura, Koji Kurokawa, Yuka Uchida, Takashi Sone, Hideharu Kimura, Kazuo Kasahara

“…The overall response and disease control rates were 77.8% (95% CI, 40.0–97.2) and 88.9% (95% CI, 51.8–97.2), respectively. …”
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Multi-source Data-driven Analysis of Deformation and Influencing Factors for Expansive Soil Canal Slopes by ZHANG Yuhan, HU Jiang, LI Xing

“…This approach facilitates a comprehensive analysis of deformation patterns at the slope surface and various subsurface depths, while elucidating the dominant controlling factors governing expansive soil canal slope behavior.Results and Discussions　The study focused on a deep excavated expansive soil canal section (Stake 8+886~12+921) of a major water diversion project, yielding the following key findings: 1) The analysis of 128 Sentinel-1A images from March 2017 to December 2021 revealed that the deformation data obtained through SBAS-InSAR method showed less than 3mm discrepancy with surface vertical displacement measurements at monitoring points (fourth-stage berm at 9+363 and third-stage berm at 11+400), with consistent deformation trends, confirming the reliability of SBAS-InSAR for canal slope deformation monitoring. 2) The study section exhibited LOS deformation rates ranging from -10 to 24 mm/a, demonstrating overall uplift characteristics, with positive LOS deformation showing annual increase. …”
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Controlled-release fertilizer affects leaf nitrogen allocation and photosynthesis to improve nitrogen use efficiency and yield in the sunflower field by Wenhao Ren, Xianyue Li, Xianyue Li, Xianyue Li, Tingxi Liu, Tingxi Liu, Ning Chen, Maoxin Xin, Qian Qi, Bin Liu

“…Controlled-release fertilizers (CRF) have been reported to effectively reduce the nitrogen loss by matching the release pattern with crop N demand, thus increasing the yield. …”
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