Trends in Antihypertensive Drug Use and Irrational Prescriptions Among Elderly Patients in China (2016–2023): A Nationwide Multi-Center Cross-Sectional Survey Study by Hong D, Chen W, Du S, Ren J, Lv D, Shan W, Lu X, Zhao Q

“…The overall proportion of first-line antihypertensive prescriptions was 97.47% but showed a slight declining trend (APC=− 0.66%, P=0.004). The rates of inappropriate combination medication and overall irrational prescriptions decreased, while the rate of contraindicated medication prescriptions increased (P< 0.001). …”
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Bridging micro and macroevolution: insights from chromosomal dynamics in plants by Carmen Benítez-Benítez, Ashwini V. Mohan, Rogelio Sánchez-Villegas, Inés Gómez-Ramos, Ana Valdés-Florido, Kay Lucek, Marek Slovák, Marek Slovák, Filip Kolář, Filip Kolář, Ilia J. Leitch, Modesto Luceño, Isabel Larridon, Angelino Carta, Angelino Carta, Joan Cuscó-Borràs, Enrique Maguilla, Alegría Montero-Ramírez, Patrick G. Meirmans, Alison Dawn Scott, Santiago Martín-Bravo, Marcial Escudero

“…Here, we address the following questions: Are macroevolutionary patterns of chromosome evolution the result of accumulated microevolutionary changes, or do chromosomal dynamics drive larger shifts along the speciation continuum? …”
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Comprehensive assessment of adverse event profiles associated with bispecific antibodies in multiple myeloma by Mobina Golmohammadi, Shahzad Raza, Maram Albayyadhi, Hossein Sholehrasa, Jack Khouri, Louis Williams, Doris K. Hansen, Azam Moradi, Xuan Xu, Moath Albliwi, Ali Hajj Ali, Danai Dima, Faiz Anwer, Barry Paul, Majid Jaberi-Douraki

“…PCA revealed agents with all grades and grade 3/4 showed similar clustering patterns except for three agents. Overall, our findings demonstrated the excellent efficacy on the use of BsAbs in MM; however, these agents have been linked to a unique AE profile. …”
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Characteristics of Anemia in Children Aged 6 Months to 5 Years Attending External Consultations at a Pediatric Hospital in Lisbon, Portugal by Réka Maulide Cane, Sérgio Chicumbe, Youssouf Keita, Anaxore Casimiro, Bárbara Martins Saraiva, Joana Vasconcelos, Beatriz Luzio Vaz, Afonso Sousa, Mafalda Cabral, Francisco Branco Caetano, Luís Varandas, Isabel Craveiro

“…Five children (6.8%) had normal hemoglobin but abnormal red-cell indices, with microcytic (60.0%; 3/5) or normocytic (40.0%; 2/5) patterns. Anemia rates were higher in males (55.1%), children aged 24–59 months, those residing in the Metropolitan Lisbon Area (82.6%), children whose caregivers had only basic or secondary education (58.0%), and those whose mothers were born in foreign countries (48.4%). …”
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Effects of Live and Peptide-Based Antimicrobiota Vaccines on <i>Ixodes ricinus</i> Fitness, Microbiota, and Acquisition of Tick-Borne Pathogens by Apolline Maitre, Lourdes Mateos-Hernandez, Myriam Kratou, Natalia Egri, Jennifer Maye, Manel Juan, Adnan Hodžić, Dasiel Obregón, Lianet Abuin-Denis, Elianne Piloto-Sardinas, Andrea C. Fogaça, Alejandro Cabezas-Cruz

“…The vaccination altered the feeding patterns and fitness of the ticks, with the Live vaccine group showing a higher weight and faster feeding time. …”
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Effects of Regulated Deficit Irrigation on Leaf Nutrients, Enzyme Activities, and Root Zone Soil Nutrients during Fruit Expansion and Coloration-Sugar Accumulation Stages of Citrus... by ZHONG Yun, HUANG Zhikun, ZHU Shijiang, HAO Kun, ZHU Zirong, ZHANG Wei, CHEN Hongde

“…The aim was to explore the response patterns of soil nutrients, citrus leaf nutrients, antioxidant enzyme activities, and root-zone soil nutrients to water stress under drip irrigation across different growth stages. …”
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Global burden of tuberculosis among adults aged 60 years and older, 1990-2021: Findings from the global burden of disease study 2021 by Junping Liu, Yue Zhou, Juan Guan, Yaping Liu, Weijian Song, Wei Liu, Xinle Yin, Yuqin Liu, Ting Li, Long Jin, Lihan Zhang, Yunkai Li, Lin Wu, Nan Wang, Zhaoyue Liu, Xinru Liu, Yanfu Wang, Qunhong Wu, Libo Liang

“…Results: A decreasing trend in age-standardized incidence rate, age-standardized mortality rate, and disability-adjusted life-years rates for TB and drug-susceptible TB was observed among the elderly population worldwide, whereas an upward trend was noted for MDR-TB and XDR-TB. …”
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Effects of intravenous immunoglobulin on the negatively transformed subpopulations of neutrophilic granulocytes in newborns with congenital pneumonia and neonatal sepsis by I. V. Nesterova, S. V. Kovaleva, G. A. Chudilova, L. V. Lomtatidze, T. V. Smerchinskaya, V. N. Chapurina

“…Testing of NG population included the following parameters: counting the numbers of NG subpopulations which simultaneously expressed CD11b CD64, CD32, CD16, as well as their phenotypic patterns, with regard of the receptor expression density (MFI) using flow cytometric techniques. …”
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Prevalence and determinants of hypertension in rwanda: a secondary data analysis using the WHO STEPS survey 2022 by Jean Damascene Hagenimana, Kagisha Divine Pascaline, Felix K. Rubuga, Kelly Mwiza, Sabine Musange F., Nathalie Umutoni, Caroline Mudereri, Jocelyne Uwitonze, Emmanuel Christian Nyabyenda, Piero I. Mazimpaka, Olivier N. Wane, Eric remera, Uwimana Aline, Marie Rosette NAHIMANA, Jeanine Condo, Gashaija Absolomon

“…While previous national surveys have documented its burden, updated analysis of current prevalence patterns and determinants is needed to inform contemporary prevention strategies. …”
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Biogeochemical responses to water management: Insights from the regulated Geum River, Korea by Min-Young Lee, Tae-Hoon Kim, Yongwon Kim, Hyebin Kim, Tae-Woo Kang, Sung-Eun Park

“…We compared conditions during August 2021 (gate-closing) and August 2022 (gate-opening), periods with starkly different residence times (3.5 vs. 0.5 days) that resulted in distinct biogeochemical dynamics. …”
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Resin‐coated urea effectively simulates the chronic dynamics of natural nitrogen deposition by Yi Zhao, Yuguang Ke, Honghui Wu, Chong Xu, Xiwen Li, Yann Hautier, Elizabeth T. Borer, Qiang Yu

“…We then compared the N release rate of the coated fertilizer to rate of natural N deposition to assess its effectiveness in replicating the temporal pattern of N deposition. …”
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Hydrodynamic Performance and Cavitation Analysis in Bottom Outlets of Dam Using CFD Modelling by Omid Aminoroayaie Yamini, S. Hooman Mousavi, M. R. Kavianpour, Ramin Safari Ghaleh

“…The service gate controls the outlet flow rate, and whenever this gate is out of order, the emergency gate which is located at upstream is utilized. …”
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Outpatient Testing for HIV in Italy, 2018–2023—Preliminary Data by Claudio Galli, Vincenza Regine, Anna Caraglia, Francesca Centrone, Maria Chironna, Gianluca Cruschelli, Massimo Farinella, Valentina Annachiara Orlando, Chiara Pasqualini, Monia Puglia, Lucia Pugliese, Laura Rancilio, Lara Tavoschi, Fabio Voller, Barbara Suligoi

“…We started a research project aimed at assessing testing rates for HIV infection among Italian outpatients in 2018–2023. …”
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Eruptive modes and hiatus of volcanism at West Mata seamount, NE Lau basin: 1996–2012 by Robert W. Embley, Susan G. Merle, Edward T. Baker, Kenna H. Rubin, John E. Lupton, Joseph A. Resing, Robert P. Dziak, Marvin D. Lilley, William W. Chadwick Jr., T. Shank, Ron Greene, Sharon L. Walker, Joseph Haxel, Eric Olson, Tamara Baumberger

“…Based on the historical eruption rates calculated using the bathymetric differencing technique, the volcano could be as young as several thousand years.…”
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Stem introducer designs and surgical technique play a significant role in achieving the optimal implant-cement interface by Bernard H. van Duren, Kevin Ilo, Sophie Walker, Mark Higgins, Benjamin V. Bloch, Andrew R. Manktelow, Hemant G. Pandit

“…A significant variation exists between PTS stem designs, associated fractured rates among them, and the design of introducers used. …”
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Impact of oral hygiene on the development of oropharyngeal neoplasms by D. G. Kiparisova, Yu. S. Kiparisov, N. S. Nurieva

“…In the patients with oropharyngeal malignancies, the CFE index was high and amounted to 15 ± 0.4 с with a preponderance of carious and extracted teeth in the pattern; the PHP index was 1.4 ± 0.1, which corresponded to a satisfactory index. …”
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Meningitis caused by Aspergillus fumigatus: a case report by Yifei Zhang, Yu Ma, Rushuang Yue, Yuan Meng, Yue Jin, Chengwei Yin, Qianmei Zhou, Rong Shi

“…Briefly, DNBs are arrayed on a patterned flow cell, where DNA polymerase catalyzes the incorporation of fluorescently labeled nucleotides during sequencing-by-synthesis. …”
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Surveillance and evaluation of vector control in Fuyang District, Hangzhou for the 19th Asian Games by XU Jie, PAN Wenjin, TANG Renyu, DU Liqun

“…The positive detection rates of adult flies and cockroach traces showed no significant pattern, with the highest rate of 7.00% and 8.33%, respectively. …”
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Design of Radiation Shielding for Optical Enclosure at HEPS Beamline Station by GUO Qingyang, SHI Hong, LIU Qiongyao, ZHANG Huijie, SHI Haoyu, MA Zhongjian, WANG Qingbin

“…Results from the calculations indicate a pattern where the dose rate from gas bremsstrahlung initially rises and subsequently falls within the back wall. …”

Avaliação comparativa e evolutiva dos protocolos de atendimento dos pacientes fissurados Comparative and evolutive evaluation of attendance protocols of patients with clef lip and... by Nivaldo Alonso, Daniela Yukie Sakai Tanikawa, Jonas Eraldo de Lima Junior, Marcus Castro Ferreira

“…Eight surgical categories were related, palate repair (35.18%) was the most utilized one, followed by lip repair (unilateral and bilateral), keeping the same distribution pattern. Secondary procedures had persisted with high rates (approximately 30%), however the number of complications decreased (no fistulae). …”
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