Efficacy and Safety of Tofacitinib in Patients with Polymyalgia Rheumatica (EAST PMR): An open-label randomized controlled trial. by Xinlei Ma, Fan Yang, Jinzhi Wu, Bei Xu, Mengdi Jiang, Yiduo Sun, Chuanying Sun, Ye Yu, Danyi Xu, Lanlan Xiao, Chunyun Ren, Chunyan Chen, Zi Ye, Junyu Liang, Jin Lin, Weiqian Chen

“…Secondary endpoints: PMR-AS score, c-reactive protein (CRP), and erythrocyte sedimentation rate (ESR) at weeks 12 and 24. Thirty-nine patients with newly diagnosed PMR received tofacitinib, and 37 patients received glucocorticoid. …”
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Estimation of duration and its changes in Lagrangian observations relying on ice floes in the Arctic Ocean utilizing a sea ice motion product by F. Zhang, F. Zhang, R. Lei, R. Lei, M. Qu, N. Li, Y. Chen, X. Pang

“…Ice trajectory terminal points did not reveal an obvious long-term tendency, but they were regulated by large-scale atmospheric circulation patterns, especially those in the early drifting stage in autumn (OND). …”
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Real-Time, Risk-Based Clinical Trial Quality Management in China: Development of a Digital Monitoring Platform by Min Jiang, Shuhua Zhao, Yun Mei, Zhiying Fu, Yannan Yuan, Jie Ai, Yuan Sheng, Ying Gong, Jingjing Chen

“…Quality findings from the early-stage, interim-stage, and conclusion-stage QC rounds of clinical trials were rated by using 3 severity grades (minor, major, or critical) and classified into 5 categories (with 4 taxonomy levels under each category). …”
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Loss of Reduction in Pediatric Distal Radius Fractures: Risk Factors From a Prospective Multicenter Registry by Apurva S. Shah, MD, MBA, Zoe E. Belardo, BA, Mark L. Miller, MD, Michael C. Willey, MD, Susan T. Mahan, MD, MPH, Divya Talwar, PhD, MPH, Donald S. Bae, MD

“…On multivariate analysis, metaphyseal bicortical fracture pattern (OR = 2.3), prereduction translation of ≥51% (OR = 2.3), and nonanatomic closed reductions (OR = 1.9) independently increased the odds of LOR. …”
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Criminal legal penalties, substance use, and overdose: a concept mapping study examining Colorado’s criminal legal penalties by Katherine LeMasters, Samantha K. Nall, Cole Jurecka, Betsy Craft, Paul J. Christine, Ryan Goodman, Jessie Henderson, Robert Haywood-James, Angela Williams, Grace Wittner, Joshua A. Barocas

“…Participants — recruited from community-based organizations — identified, rated, sorted, and categorized factors affecting criminal legal involvement, substance use, and/or overdose in their community. …”
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Analysis of influencing factors for primary membranous nephropathy complicated with atherosclerotic cardiovascular disease and establishment of a nomogram prediction model by Mirixiatijiang· Maimaiti, Zhu Guo-qiang, Su Ming-jie, Halinuer· Shadekejiang, Zhang Xue-qin, Lu Chen

“…They also had significantly higher systolic blood pressure ［130（120， 142） mmHg（1 mmHg=0.133 kPa） <italic>vs</italic> 122.0（113.5， 135.5） mmHg］， higher diastolic blood pressure ［80 （75， 90） mmHg <italic>vs</italic> 80（70， 85.5） mmHg］， higher prevalence of hypertension［142（64.8%） <italic>vs</italic> 67 （32.7%）］， and higher proportion of manual workers［60（27.4%） <italic>vs</italic> 28（13.7%）］ Additionally， lymphocyte count （LYM）， platelet count （PLT）， blood sodium concentration （Na）， blood urea nitrogen （BUN）， blood creatinine （Cr）， estimated glomerular filtration rate （eGFR）， 24-hour quantitative urine protein， glutamic transaminase， urinary occult blood， number of urinary hyaline and pathological tubular patterns， C-reactive protein （CRP）， complement C4， plasma fibrinogen， D-dimer， and centrocyte-lymphocyte ratio were all significantly different between the two groups （<italic>P</italic>&lt;0.05）. …”
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A data-driven approach to forest health assessment through multivariate analysis and machine learning techniques by Raja Waqar Ahmed Khan, Hamayun Shaheen, Muhammad Ejaz Ul Islam Dar, Tariq Habib, Muhammad Manzoor, Syed Waseem Gillani, Abeer Al-Andal, John Oluwafemi Ayoola, Muhammad Waheed

“…RF-based feature importance analysis showed tree DBH, height, regeneration rate, soil erosion, and tree density as key ecological drivers of forest health. …”
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Digital learning resource use among Swedish medical students: insights from a nationwide survey by Martin F. Bjurström, Emma Lundkvist, Louise W. Sturesson, Ola Borgquist, Robin Lundén, Malin Jonsson Fagerlund, Miklós Lipcsey, Thomas Kander

“…Several background factors influence usage patterns. These data may support institutions, program directors and teachers in their efforts to guide and improve use of digital learning tools in medical schools.…”
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Citronella oil-loaded electro-spun single and core-shell nano fibers as sustained repellent systems against Aedes aegypti by Samali Udara Liyanaarachchi, Sanjeewa K. Rodrigo, Nilwala Kottegoda, Veranja Karunaratne, Menaka Hapugoda, Tharaka Ranathunge, Lahiru Udayanga, Dushmantha Adikari

“…It was found that maintaining the outer:inner flow rate ratio at 5:2 in coaxial process is imperative to produce good fibers. …”
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Functioning in patients with major depression treated with duloxetine or a selective serotonin reuptake inhibitor in East Asia by Novick D, Montgomery W, Haro JM, Moneta MV, Zhu G, Yue L, Hong J, Duenas H, Brugnoli R

“…Depression severity was assessed using the 16-item Quick Inventory of Depressive Symptomatology-Self Report. PPS were rated using the modified Somatic Symptom Inventory. …”
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Spatio-temporal mapping reveals changes in soil organic carbon stocks across the contiguous United States since 1955 by Chenconghai Yang, Feixue Shen, Xiang Li, Wenkai Cui, Lei Zhang, Lin Yang, Chenghu Zhou

“…Abstract Understanding spatio-temporal patterns of soil organic carbon (SOC) is critical for global climate change mitigation and sustainable soil management. …”
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Effects of Hole Irrigation Device Parameters on Soil Water Characteristics Under Different Biogas Slurry Ratios by Peng Xiang, Jian Zheng, Yan Wang, You Wu

“…The lateral and vertical wetting front migration distances exhibited a well-defined power function relationship with the soil’s stable infiltration rate and infiltration time (<i>R</i>² ≥ 0.977). …”
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Assessment of predictors and mitigation strategy for therapeutic inertia in the management of hypertension: a quality improvement project by Ananyan Sampath, Shreya Deshpande, Rashmi Verma, Rajnish Joshi

“…When patient adherence was disregarded, TI increased to 49.7%. The total error rate in BP management ranged from 53.29% to 61.5%. …”
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Applying mortality data to improve emergency care planning for haemodialysis patients: a quality improvement project by Lisa Tang, Usha Appalsawmy

“…Cases involving cardiac arrest underwent further analysis, examining factors including their Clinical Frailty Score4 and the presence of a ReSPECT form.2 This review identified the underutilisation of ReSPECT forms in frail haemodialysis patients.Phase 2: we expanded the review of ReSPECT form use beyond cardiac arrest cases to include all haemodialysis patients who underwent an SJR in the same time frame, thus providing a broader perspective on ReSPECT form usage within the whole cohort.Phase 3: an intervention in the form of a departmental educational campaign, emphasising the high mortality rate among frail haemodialysis patients and, thus, the importance of advance care planning, was carried out. …”
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Epigenetic dysregulation-induced metabolic reprogramming fuels tumor progression in bladder cancer by Jian Zhang, Xiaosong Fan, Xu Xu, Yichao Han, Weixing Yu, Bicheng Yang, Yanling Chen, Shaolin Zhang

“…BackgroundBladder cancer remains a significant global health challenge with a high mortality rate despite advancements in treatment modalities. …”
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Mechanisms behind grouting pressure jumping in low-permeability limestones and techniques for grouting pressure control by Zhenli FAN, Lutong CAO, Yong CUI, Zhiwei ZHANG, Fengda ZHANG

“…Therefore, such grout was prone to block fractures, and the pressure rise rate was approximately 10 times greater than that of the cement grout. …”
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Assessment of Water Resources Carrying Capacity and Analysis of Its Coupling Coordination in the Yangtze River Economic Belt by XIONG Ying, JIANG Yi-xin, CHEN Si-xuan

“…Analysis of influencing factors identified the proportion of tertiary industry, urbanization rate, and per capita daily domestic water consumption as the three factors most strongly correlated with water resources carrying capacity. …”
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Assessment of heavy metal pollution sources and environmental capacity of typical farmland soils in northwestern Zhejiang based on the geological background of black rock series by Mei-hua Wang

“…Principal component analysis extracted four principal components with a cumulative contribution rate of 78.92%, and the spatial distribution differences were obvious. …”
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Eco-friendly QbD-optimized chromatographic method for simultaneous analysis of metronidazole and nicotinamide with applications in permeation, stability, and sustainability evaluat... by Kanaka Parvathi Kannaiah, Mohamed A. M. Ali, Hemanth Kumar Chanduluru, Anis Ahmad Chaudhary, Mahmoud El-Maghrabey, Reem H. Obaydo, Galal Magdy, Mohamed A. El Hamd

“…The in vitro permeation curve, constructed by plotting mass flux in. μg/cm2.hour against mid-time in hours, showed similar permeation patterns for both drugs over time. The permeation coefficient (Kp) values for MTZ and NCT were 0.016 and 0.012 × cm−2. hour−1, respectively. …”
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Longitudinal evaluation of common and unique brain-networks in variants of primary progressive aphasia by Rajan Kashyap, Rose Dawn Bharath, Changsong Zhou, Kyrana Tsapkini, John E. Desmond, SH Annabel Chen, Kaviraja Udupa, PT Sivakumar, Sagarika Bhattacharjee

“…To validate the rsfMRI networks and the longitudinal changes, we evaluated the grey matter (GM) volume, GM atrophy and the rate-of-atrophy of the brain areas. To corroborate the findings, we applied persistent homology on the structural networks derived from diffusion tensor images. …”
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