Breaking barriers: targeted delivery of resveratrol in lung cancer using folate-integrated and pH-responsive hybrid nanocarriers by Sanjoy Das, Malay K. Das, Taison Jamatia, Nayan Ranjan Ghose Bishwas, Dhritiman Roy, Emdormi Rymbai

“…The amount of RSV released from FOL-RSV-LPHNCs was 96.53 ± 2.16% at pH 5.8 and 23.21 ± 2.01% at pH 7.4, indicative of a pH-responsive release pattern and good physiological stability. In vitro cytotoxicity study revealed that FOL-RSV-LPHNCs remarkably inhibited the viability of A549 cells and produced negligible toxic effect on Wi-38 healthy cells. …”
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Physiological insights into the responses of tea plants to aluminum through an integrated transcriptomic and metabolomic analysis by Xinwan Zhang, Shijie Luo, Xiali Ye, Lin Liu, Xinxin Jia, Deyuan Jiang, Weiwei Wen

“…Compared to 0 mM Al treatment, low Al concentrations (0.4 mM) enhanced root vitality by 8.91%, while higher Al concentrations (10 and 100 mM) reduced root vigor by 19.31% and 76.81%, respectively. In a similar pattern, the electron transfer rate in leaves remained stable under low Al levels but significantly decreased under high Al conditions. …”
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Impact of Malaria Diagnostic Technologies on the Disease Burden in the Sub-Saharan Africa by Josephine Wambani, Patrick Okoth

“…However, in certain areas, the rate of decline has slowed or even reversed the gains made so far. …”
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Identification of endothelial INSR as an osteosarcoma-related biomarker and therapeutic target based on weighted gene co-expression network analysis by Xu Yingkai, Jiang Jianfeng, Hu Zhiyong, Zhou Zhifeng, Wang Lei

“…Abstract Background Osteosarcoma (OS) is the most common primary malignant bone tumor characterized by a high rate of metastasis. The clinical efficacy of current targeted drugs for OS is limited, highlighting the urgent need to identify novel therapeutic targets. …”
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Dr Papineau Meets Dr Masquelet—Management of Open Calcaneal Fractures, Combining Two Techniques: A Case Report by Shuvendu P Roy, Yogendra Gupta, Gurinder Bedi, Vishwadeep Sharma

“…Aim and background: Open fractures of the calcaneum are often the source of significant morbidity due to the high rate of wound infection and significant morbidity, ranging from malunion to amputation. …”
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Fluid–solid coupling productivity analysis of multi-stage fractured horizontal wells in shale reservoirs by Qian QI, Ming YUE, Weiyao ZHU, Wenjiang MA

“…The simulation results of the model align with actual field data, showing that gas production follows an “L-shaped” decline pattern with a coincidence rate exceeding 70%, verifying the model’s accuracy.…”
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Safety and efficacy of prone position ventilation in patients with severe pneumonia in neurosurgical intensive care units by CHENG Longyang，LI Jun，LI Shaoya，LI Chuanqing，XU Manman，WANG Rong，ZHAO Penglai

“…PaO2 values followed a similar pattern：（79.63±4.81）mmHg，（89.90±6.83）mmHg，（106.98±12.26）mmHg，（130.40±12.03）mmHg and（135.68±13.95）mmHg，also demonstrating a significant increase（F=219.963，P<0.01）. …”
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Clinical characteristics and outcomes of non-tuberculous mycobacterial pulmonary infections after hematopoietic stem cell transplantation: A retrospective cohort study by Zahia Esber, Hamza Salam, Shefali Godara, Ayman Soubani

“…The most common radiologic pattern was nodular infiltrates in 15 (29.4%) patients. …”
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Cutis verticis gyrata in a Patient with Familial presenile sebaceous hyperplasia Presenting as &amp;ldquo;Leonine facies&amp;rdquo;: A Rare Case by Sutedja EK, Sutedja E, Ruchiatan K, Faldian Y, Yogya Y, Dwiyana RF, Maharani RH, Budiarsa M

“…Familial presenile sebaceous hyperplasia (FPSH), a rare variant of sebaceous hyperplasia, follows an autosomal dominant inheritance pattern with incomplete penetrance and variable severity among family members. …”
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Isokinetic knee strength as a predictor of cardiorespiratory responses during loaded aerobic capacity test in elite athletes by Bekir Çar, Ahmet Kurtoğlu, Özdemir Atar, Musa Türkmen, Özgür Eken, Mehmet Soyler, Monira I. Aldhahi

“…Cardiorespiratory parameters—average breath volume (ABV), average breath frequency (ABF), auxiliary oxygen density (AOD), and heart rate (HR)—were recorded during the Bruce Protocol conducted under two conditions: unloaded and with a 10 kg loaded vest. …”
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Neuroendocrine tumors of the digestive system: pathologic and molecular characteristics by V. V. Delektorskaya

“…In contrast, poorly differentiated neuroendocrine carcinomas have diffuse growth pattern, high-grade nuclear atypia and cellular proliferation, necrosis. …”
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Network meta-analysis of erlotinib, gefitinib, afatinib and icotinib in patients with advanced non-small-cell lung cancer harboring EGFR mutations. by Wenhua Liang, Xuan Wu, Wenfeng Fang, Yuanyuan Zhao, Yunpeng Yang, Zhihuang Hu, Cong Xue, Jing Zhang, Jianwei Zhang, Yuxiang Ma, Ting Zhou, Yue Yan, Xue Hou, Tao Qin, Xiaoxiao Dinglin, Ying Tian, Peiyu Huang, Yan Huang, Hongyun Zhao, Li Zhang

“…Pooled data on objective response rate (ORR), progression free survival (PFS), overall survival (OS) were calculated. …”
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Demographic and clinical characteristics of patients with benign bone tumors: Evidence of bimodal age distribution in a Hispanic population by Blake C. Martin, Mohammad Khalil, Juan Lopez-Alvarenga, Michael Sander

“…This indicates an incidence rate of 0.00018 per person-year. The average age was 38.8 years (SD 24.0), with females representing 58 % of the sample. …”
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Reduced Inter-Element Interference mmWave MIMO Antenna and Its Application in WBAN by Jawad Ahmad, Mohammad Hashmi

“…A specific absorption rate (SAR) analysis confirmed that the design complies with safety standards for both 1g and 10g tissue models. …”
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The Friendship Questionnaire, autism, and gender differences: a study revisited by Felicity Sedgewick, Jenni Leppanen, Kate Tchanturia

“…On the URCS, we took the data from those who rated specific close relationships and found that autistic people scored this relationship more highly than non-autistic adults did. …”
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Early Recurrence of Hepatocellular Carcinoma in Patients without Microscopic Vascular Invasion: Clinicopathological Characteristics and Risk Factors by Ngo HTT, Nguyen DD, Dang MX, Doan TTP, Thai TT

“…Microscopic features of both tumor and non-tumor liver tissue were assessed using Hematoxylin-Eosin-stained slides.Results: The majority of patients were male (78.3%) and had cirrhosis (72.5%). The early recurrence rate was 31.9%, with most recurrences occurring between 6- and 18-month post-surgery. …”
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Factors associated with interstitial lung disease in patients with rheumatoid arthritis by Benyapa Suppa-Udom, Supparerk Disayabutr, Suwimon Wonglaksanapimon, Krittachat Butnian, Wanruchada Katchamart

“…Patients exhibited low disease activity [mean Disease Activity Score 28-erythrocyte sedimentation rate score (SD) 2.69 (0.90)] and mild functional impairment [median Health Assessment Questionnaire score (range) 0.25 (0–0.63)]. …”
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Comparative analysis of START and CAVI arterial stiffness scores in hypertensive patients by A. N. Sumin, A. V. Shcheglova, I. B. Bakholdin

“…In the older age group (61-70 years), the median START index was 7,27, for the CAVI index — 8,4 (p&gt;0,05).  The growth pattern of the START score with age was higher by 38,5% than the CAVI index by 25,6% (p=0,034). …”
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Clinical Characteristics of the Premature Ejaculation Sufferers in Aegean Region of the Turkey: A Multicentre, Observational Study by Ahmet Cihan, Ömer Demir, Ali Şahin, Fatih Zeren, Deniz Bolat, Burak Özçift, Abdulkadir Pektaş, Ertan Can, Bilal Gümüş, Tahir Turan, Ahmet Bölükbaşı, Haluk Erol, Ahmet Adil Esen

“…Subjects in the PE group gave poor ratings than non-PE subjects. Partner responses were similar pattern. …”
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Influence of the extent of cervical lymph node dissection and lymph nodes metastases on prognosis in a cohort of dogs with oral malignant melanoma treated by surgical resection and... by Davide Giacobino, Matteo Olimpo, Erica Ilaria Ferraris, Greta Martinelli, Lorella Maniscalco, Mariateresa Camerino, Federica Riccardo, Federica Cavallo, Lidia Tarone, Marzia Cino, Alfredo Dentini, Selina Iussich, Elena Lardone, Luca Manassero, Raffaella De Maria, Paolo Buracco, Emanuela Morello

“…The overall LN metastatic rate was 31%; metastasis was found mostly in the mandibular lymph center (83%). …”
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