Dietary supplementation with L-carnitine elevates intracellular carnitine levels and affects gene expression of SLC25A20 and COX4I1, as well as non-mitochondrial respiration of bov... by Leonie Seemann, Susanne Kersten, Susanne Bühler, Fabian Billenkamp, Ulrich Meyer, Christian Visscher, Korinna Huber, Erika Most, Klaus Eder, Sven Dänicke, Jana Frahm

“…The same applied for PBMC mitochondrial functionality and metabolic activity as assessed by ex vivo approaches, whereas non-mitochondrial respiration rate was significantly affected by L-carnitine supplementation over time. …”
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Type II diabetes in systemic sclerosis patients: insights from an observational, multicenter study of GIRRCS (Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale) by Vasiliki Liakouli, Giulio Forte, Piero Ruscitti, Luca Navarini, Francesca Bellisai, Francesco Caso, Giuliana Guggino, Lidia La Barbera, Chiara Rizzo, Ada Corrado, Paola Triggianese, Alberto Lo Gullo, Giuseppe Mandraffino, Luca Cantarini, Bruno Frediani, Paola Cipriani, Francesco Paolo Cantatore, Maria Sole Chimenti, Elvira Favoino, Federico Perosa, Annamaria Iagnocco, Roberto Giacomelli, Francesco Ciccia

“…SSc patients with T2D were significantly older (P < 0.007) and exhibited: higher prevalence of late-stage capillaroscopic pattern (P < 0.001), severe reduction in forced vital capacity (FVC < 50%; P < 0.000), moderate reduction in total lung capacity (TLC 50–69%; P < 0.011), electrocardiographic signs of right ventricular hypertrophy (P < 0.018), higher prevalence of pulmonary arterial hypertension (PAH) confirmed by right heart catheterization (RHC) (P < 0.037) and higher prevalence scleroderma renal crisis (SRC) (P < 0.001); elevated erythrocyte sedimentation rate (ESR) (P < 0.022), and ANA positivity. …”
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Identification of CaVβ1 Isoforms Required for Neuromuscular Junction Formation and Maintenance by Amélie Vergnol, Aly Bourguiba, Stephanie Bauché, Massiré Traoré, Maxime Gelin, Christel Gentil, Sonia Pezet, Lucile Saillard, Pierre Meunier, Mégane Lemaitre, Julianne Perronnet, Frederic Tores, Candice Gautier, Zoheir Guesmia, Eric Allemand, Eric Batsché, France Pietri-Rouxel, Sestina Falcone

“…Voltage-gated Ca²⁺ channels (VGCCs) are regulated by four CaVβ subunits (CaVβ1–CaVβ4), each showing specific expression patterns in excitable cells. …”
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hnRNPA2B1 recognizes RNA virus SFTSV infection through mitochondrial DNA by Xin-bo Huang, Yue Zhang, Jing-wen Fan, Xin-yu Yu, Yun-lan Fang, Jin-xin Ren, Bin-yan Liu

“…However, it remains largely unclear whether A2B1 could function as a nucleic acid pattern-recognition receptor during cytoplasmic RNA virus infection. …”
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Dependence of Indicators of Daily Blood Pressure Monitoring on Activity of Pathological Process in Patients with Systemic Lupus Erythematosus by Abrahamovych O., Abrahamovych U., Kushyna A., Guta S., Synenkyi O.

“…According to the first goal was rated the BP in the SLE patients during the period of 24 hours, for which: a) were examined the average daily, maximum and minimum levels of systolic blood pressure (SBP), diastolic blood pressure (DBP), the average blood pressure; b) was analysed the daily index (DI) of SBP, DBP and the average blood pressure; c) was examined the time index (TI) of SBP, DBP and the average blood pressure. …”
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Sewage sludge from Taxco de Alarcón wastewater treatment plant as substrate to cultivate Panicum maximum by Erik Yoel Carreto-Morales, Jazmin Alaide López-Díaz, Mariana Martínez-Castrejón, Oscar Talavera-Mendoza, Roberto Carlos Almazán-Núñez, Giovanni Hernández-Flores

“…The response variables analyzed for MG were germination time (one month after plant emergence), height (HMG), growth rate GrMG, and yield (YMG), whereas in the SS and PS the content of organic matter was analyzed. …”
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Regional lymph node invasion in pediatric non-rhabdomyosarcoma soft tissue sarcoma: an international cohort study from the International Soft Tissue Sarcoma ConsortiumResearch in c... by Daniel Orbach, Matthieu Carton, Amadeus T. Heinz, Lise Borgwardt, J Herve Brisse, Carlo Morosi, Erin R. Rudzinski, Akmal Safwat, Monika Sparber-Sauer, Stephanie Terezakis, Andrea Ferrari, Aaron R. Weiss, William H. Meyer, David O. Walterhouse, Timothy B. Lautz

“…We therefore to analyze the rate of N1 at diagnosis, the pattern of nodal relapse, and the prognostic impact of N1 in pediatric patients with NRSTS. …”
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Diffusion and Risks of House Prices in the Netherlands by Alfred Larm Teye

“… The rate of home-ownership has increased significantly in many countries over the past decades. …”
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Clinical features of post-COVID-19 period. Results of the international register “Dynamic analysis of comorbidities in SARS-CoV-2 survivors (AKTIV SARS-CoV-2)”. Data from 6-month f... by G. P. Arutyunov, E. I. Tarlovskaya, A. G. Arutyunov, Yu. N. Belenkov, A. O. Konradi, Yu. M. Lopatin, A. P. Rebrov, S. N. Tereshchenko, A. I. Chesnikova, H. G. Hayrapetyan, A. P. Babin, I. G. Bakulin, N. V. Bakulina, L. A. Balykova, A. S. Blagonravova, M. V. Boldina, A. R. Vaisberg, A. S. Galyavich, V. V. Gomonova, N. Yu. Grigorieva, I. V. Gubareva, I. V. Demko, A. V. Evzerikhina, A. V. Zharkov, U. K. Kamilova, Z. F. Kim, T. Yu. Kuznetsova, N. V. Lareva, E. V. Makarova, S. V. Malchikova, S. V. Nedogoda, M. M. Petrova, I. G. Pochinka, K. V. Protasov, D. N. Protsenko, D. Yu. Ruzanau, S. A. Sayganov, A. Sh. Sarybaev, N. M. Selezneva, A. B. Sugraliev, I. V. Fomin, O. V. Khlynova, O. Yu. Chizhova, I. I. Shaposhnik, D. A. Shchukarev, A. K. Abdrahmanova, S. A. Avetisian, H. G. Avoyan, K. K. Azarian, G. T. Aimakhanova, D. A. Ayipova, A. Ch. Akunov, M. K. Alieva, A. V. Aparkina, O. R. Aruslanova, E. Yu. Ashina, O. Yu. Badina, O. Yu. Barisheva, T. I. Batluk, A. S. Batchayeva, R. A. Bashkinov, A. M. Bitieva, I. U. Bikhteyev, N. A. Borodulina, M. V. Bragin, A. M. Budu, G. A. Bykova, K. R. Vagapova, D. D. Varlamova, N. N. Vezikova, E. A. Verbitskaya, O. E. Vilkova, E. A. Vinnikova, V. V. Vustina, E. A. Gаlova, V. V. Genkel, E. I. Gorshenina, E. V. Grigorieva, E. Yu. Gubareva, G. M. Dabylova, I. A. Demchenko, O. Yu. Dolgikh, M. Y. Duyshobayev, D. S. Evdokimov, K. E. Egorova, A. N. Ermilova, A. E. Zheldybayeva, N. V. Zarechnova, Yu. D. Zimina, S. Yu. Ivanova, E. Yu. Ivanchenko, M. V. Ilina, M. V. Kazakovtseva, E. V. Kazymova, Yu. S. Kalinina, N. A. Kamardina, A. M. Karachenova, I. A. Karetnikov, N. A. Karoli, M. K. Karsiev, D. S. Кaskaeva, K. F. Kasymova, Zh. B. Kerimbekova, A. Sh. Kerimova, E. S. Kim, N. V. Kiseleva, D. A. Klimenko, A. V. Klimova, O. V. Kovalishena, E. V. Kolmakova, T. P. Kolchinskaya, M. I. Kolyadich, O. V. Kondriakova, M. P. Konoval, D. Yu. Konstantinov, E. A. Konstantinova, V. A. Kordukova, E. V. Koroleva, A. Yu. Kraposhina, T. V. Kriukova, A. S. Kuznetsova, T. Yu. Kuzmina, K. V. Kuzmichev, Ch. K. Kulchoroeva, T. V. Kuprina, I. M. Kouranova, L. V. Kurenkova, N. Yu. Kurchugina, N. A. Kushubakova, V. I. Levankova, N. A. Lyubavina, N. A. Magdeyeva, K. V. Mazalov, V. I. Majseenko, A. S. Makarova, A. M. Maripov, A. A. Marusina, E. S. Melnikov, N. B. Moiseenko, F. N. Muradova, R. G. Muradyan, Sh. N. Musaelian, A. O. Myshak, E. S. Nekaeva, N. M. Nikitina, B. B. Ogurlieva, A. A. Odegova, Yu. M. Omarova, N. A. Omurzakova, Sh. O. Ospanova, E. V. Pahomova, L. D. Petrov, S. S. Plastinina, V. A. Pogrebetskaya, D. V. Polyakov, D. S. Polyakov, E. V. Ponomarenko, L. L. Popova, N. A. Prokofeva, I. A. Pudova, N. A. Rakov, A. N. Rakhimov, N. A. Rozanova, S. Serikbolkyzy, A. A. Simonov, V. V. Skachkova, D. V. Soloveva, I. A. Soloveva, I. M. Sukhomlinova, A. G. Sushilova, D. R. Tagayeva, Yu. V. Titojkina, E. P. Tikhonova, D. S. Tokmin, A. A. Tolmacheva, M. S. Torgunakova, K. V. Trenogina, N. A. Trostianetckaia, D. A. Trofimov, M. A. Trubnikova, A. A. Tulichev, A. T. Tursunova, N. D. Ulanova, O. V. Fatenkov, O. V. Fedorishina, T. S. Fil, I. Yu. Fomina, I. S. Fominova, I. A. Frolova, S. M. Tsvinger, V. V. Tsoma, M. B. Cholponbaeva, T. I. Chudinovskikh, O. A. Shevchenko, T. V. Sheshina, E. A. Shishkina, K. Yu. Shishkov, S. Yu. Sherbakov, E. A. Yausheva

“…The highest mortality rate was observed in the first 3 months in the group of patients with class II-IV heart failure, as well as in patients with cardiovascular diseases and cancer. …”
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Reduced threat-safety discrimination and generally enhanced generalization responses in adversity exposed youth with emerging psychiatric symptoms by Zhiling Qiao, Celine Samaey, Lise Jennen, Victor Mazereel, Davy Vancampfort, Bart Boets, Ruud van Winkel

“…Contrary to our hypothesis, this effect was driven by their enhanced risk ratings for the safety cue rather than blunted responses to the danger cue. …”
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Breeding of a new mid-to-late ripening apple cultivar Wangyuebingcui by XU Haihong, YANG Kai, LI Guangjin, ZHANG Guoqiang, TIAN Ge, AI Bohao, LI Xuqiang, WANG Junya

“…The cultivar combines high budbreak rate with moderate branching capacity, exhibiting spur-type growth pattern, sustained cluster-base productivity, and axillary flowering propensity. …”
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Low-level atmospheric turbulence dataset in China generated by combining radar wind profiler and radiosonde observations by D. Meng, D. Meng, J. Guo, J. Guo, J. Chen, X. Guo, N. Li, Y. Sun, Z. Zhang, Z. Zhang, N. Tang, H. Xu, T. Chen, R. Yang, J. Hua

“…This dataset includes squared Brunt–Väisälä frequency (<span class="inline-formula"><i>N</i>²</span>), turbulent dissipation rate (<span class="inline-formula"><i>ε</i></span>), vertical eddy diffusivity (<span class="inline-formula"><i>K</i></span>), inner scale (<span class="inline-formula"><i>l</i>₀</span>), and buoyancy length scale (<span class="inline-formula"><i>L</i>_B</span>), which are provided twice daily at 00:00 and 12:00 UTC with a vertical resolution of 120 m, covering altitudes from 0.12 to 3.0 km above ground level (a.g.l.). …”
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BASSET: Bandpass-adaptive Single-pulse Search Toolkit—Optimized Subband Pulse Search Strategies for Faint Narrowband Fast Radio Bursts by J. H Cao, P. Wang, D. Li, Q. H. Pan, K. Mao, C. H. Niu, Y. K. Zhang, Q. Y. Qu, W. J. Lu, J. S. Zhang, Y. H. Zhu, Y. D. Wang, H. X. Chen, X. L. Chen, J. H. Fang, Y. Feng, H. Gao, Y. F. Huang, J. Li, C. C. Miao, C. W. Tsai, J. M. Yao, S. P. You, R. S. Zhao, Q. Z. Liu, S. M. Weng, S. H. Yew, J. Zhang, L. Zhang, E. Gügercinoğlu, D. K. Zhou, W. W. Zhu

“…In conjunction with the pulse calibration and the Markov Chain Monte Carlo simulated injection experiments, this work updates the quantified parameter space of the detection rate. Moreover, a parallel-accelerated version of the BASSET code was provided and evaluated through simulation. …”
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Effect of cholesterol on distribution, cell uptake, and protein corona of lipid microspheres at sites of cardiovascular inflammatory injury by Lingyan Li, Xingjie Wu, Qianqian Guo, Yu'e Wang, Zhiyong He, Guangqiong Zhang, Shaobo Liu, Liping Shu, Babu Gajendran, Ying Chen, Xiangchun Shen, Ling Tao

“…Then, the slow cellular uptake rate observed for CH@LM contributed to a prolonged duration of drug efficacy. …”
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Screening for psychosocial distress and depression among cancer patients in a regional cancer centre in Nigeria: a cross-sectional study by Nwosu et al.

“…The predictors of psychosocial distress were the presence of co-morbidities (AOR=2.6; 95%CI: 1.3- 5.1) and good self-rated health status (AOR= 0.2; 95%CI: 0.1-0.3). The predictors of depression were the outpatient setting of care (AOR=0.4; 95%CI: 0.2-0.7) and good self-rated health (AOR= 0.3; 95%CI: 0.2-0.4). …”

Automation of multicriteria ranking of students using ePortfolio by L. A. Ponomareva, O. N. Romashkova, A. N. Belyakova, V. S. Zabolotnikova

“…The authors described the scheme of the information system (IS) operation “ePortfolio”, presented a process interaction pattern for the portfolio formation, as well as a diagram of business processes under calculating an individual rating. …”
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Planning with self‑organised initiatives by Igor Tempels Moreno Pessôa

“… Over the last half century, the Global South has faced a strong rise in the rate of urbanisation. Although this process differs from region to region, rapid urbanisation has created many challenges for countries in the Global South. …”
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Pain chronobiology in clinical trial participants with fibromyalgia: a comparison with neuropathic pain by Ryan Navarro, Wilma Hopman, Ian Gilron

“…In these trials, pain intensity (0–10 scale) was rated at 8:00 am and 8:00 pm during a 7-day pretrial baseline period and throughout each trial. …”
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Assessing aesthetic impressions with pictorial measures: A novel approach in empirical aesthetics by Ivan Z. Stojilović

“…Findings revealed that the size of marked regions modestly predicted ratings on Interestingness and Comprehensibility scales, though the explained variance was limited. …”
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Risk of developing drug abuse in administration of a new hexaazaisowurtzitane derivative-based analgesic (experimental study) by S. G. Krylova, T. N. Pove’teva, K. A. Lopatina, Yu. V. Nesterova, E. P. Zueva, O. G. Afanas’eva, P. V. Kulpin, E. A. Kiseleva, N. I. Suslov, D. A. Kulagina, S. V. Sysolyatin, V. V. Zhdanov

“…Previous in vivo and in silico studies (docking, molecular modeling, molecular dynamics simulation) on the multi-target mechanism of thiowurtzine explain the absence of its morphine-like effect by the fact that the major targets of the analgesic are TRPA1 receptors and voltage-gated Ca 2+ channels. With a high degree of probability, the conclusions made herein predict no drug abuse development when thiowurtzine is used in the clinical setting. …”
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