Integrative bulk and single-cell transcriptomic analysis identifies a migrasome-associated lncRNA signature predictive of prognosis and immune landscape in clear cell renal cell ca... by Junlin Shen, Chun Wang, Mingpeng Zhang, Bin Chen, Liwei Liu, Jing Tian, Zhiqun Shang

“…IntroductionClear cell renal cell carcinoma (ccRCC) is characterized by high recurrence and metastasis rates, leading to poor prognosis. Migrasomes, a class of organelles mediating intercellular communication, and long noncoding RNAs (lncRNAs) both play critical roles in tumor progression; however, the prognostic significance of migrasome-associated lncRNAs in ccRCC remains unclear.MethodsMigrasome-associated lncRNAs were identified using The Cancer Genome Atlas (TCGA) dataset, and a prognostic risk signature was constructed. …”
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Bacterial pathogens in orthopedic implant infection and their resistance to antimicrobial therapy: A retrospective analysis by Ameer Hamza Mahmood Ul Hassan, Nehala Nooz, Humayoon Ashraf, Obaid Ur Rehman

“…Background: Orthopedic implant infections pose a significant challenge in healthcare due to increasing rates and the emergence of multidrug-resistant (MDR) pathogens. …”
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Groundwater Circulation Within the Mountain Block: Combining Flow and Transport Models With Magnetotelluric Observations to Untangle Its Nested Nature by D. Gonzalez‐Duque, J. D. Gomez‐Velez, M. A. Person, S. Kelley, K. Key, D. Lucero

“…As a proof‐of‐concept, we use a coupled groundwater flow and transport model to design a series of numerical experiments that explore the role of geology, topography, and weathering rates in groundwater circulation and their resulting resistivity patterns. …”
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The Impact of the COVID-19 Pandemic on Research into Chinese University Students’ Mental Health: A Bibliometric Analysis by Zhexian Zhu, Michela Montesi

“…Background: The COVID-19 pandemic increased anxiety and depression rates, prompting heightened research activity in mental health, particularly among vulnerable populations like university students. …”
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Long-term health consequences and costs of changes in alcohol consumption in England during the COVID-19 pandemic. by Joshua Card-Gowers, Sadie Boniface, Jamie Brown, Loren Kock, Alexander Martin, Lise Retat, Laura Webber

“…Early real-world data corroborate the findings of the modelling study. Increased rates of alcohol harm and healthcare costs are not inevitable but evidence-based policies and interventions are required to reverse the impacts of the pandemic on alcohol consumption in England.…”
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Infections and mortality in ICU patients undergoing continuous renal replacement therapy: a retrospective cohort study by Danica Quickfall, Ashley La, Jennifer Pisano, Patrick Costello, Samantha Gunning, Jay L. Koyner

“…Conclusion ICU patients receiving CRRT experience high rates of multidrug-resistant infections and associated mortality. …”
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Unraveling the Nexus: how street network morphology influences crime in Detroit by Yuanyuan Mao, Shuqi Huang, Yueqiao Ning, Can Wang, Wenchao Li, Ziheng Huang, Shanhe Jiang, Yanqing Xu

“…Neighborhoods with a higher proportion of community roads, increased street permeability for pedestrians, a higher density of dining establishments, and elevated rental rates were more likely to experience criminal activities. …”
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Design and Testing of Miniaturized Electrically Driven Plug Seedling Transplanter by Meng Chen, Yang Xu, Changjie Han, Desheng Li, Binning Yang, Shilong Qiu, Yan Luo, Hanping Mao, Xu Ma

“…In the field test, at three transplanting speeds of 80 plants/min, 100 plants/min, and 120 plants/min, the transplanting success rates were 94.17%, 90.83%, and 88.33%, respectively. …”
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Clinical Features of Liver Injury Induced by Immune Checkpoint Inhibitors in Japanese Patients by Koji Imoto, Motoyuki Kohjima, Tomonobu Hioki, Tomoyuki Kurashige, Miho Kurokawa, Shigeki Tashiro, Hideo Suzuki, Akifumi Kuwano, Masatake Tanaka, Seiji Okada, Masaki Kato, Yoshihiro Ogawa

“…Immune checkpoint inhibitors (ICIs) have improved the survival rate of patients carrying various malignant neoplasms. …”
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Identification of clusters related to programmed cell death and potential prognostic biomarkers for immunotherapy response in endometrial cancer by Shan Lu, Yiyun Wei, Liuyan Chen, Jinlian Cheng, Liuyan Qin, Xuemei Lu, Lihong Pang

“…Abstract Endometrial cancer (EC) is one of the few malignancies with increasing incidence and mortality rates. Targeted therapy and immunotherapy have become pivotal treatment strategies for EC patients. …”
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Analysis of common respiratory pathogens and epidemiological trends during peak influenza seasons in Tengzhou by Huiping Ma, Jinghai Hou, Jing Wang, Zhaolin Yuan, Sijin Man

“…Statistical analyses were performed to evaluate infection patterns and their associations with age and other variables. …”
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A four-year, mixed-family and community-based growth monitoring and promotion program using multi-level modeling to address undernutrition in children in Cambodia by Po-Yen Liu, Yen-Ting Lin, Yee-Hsuan Chiou, Maw-Sheng Lee

“…At baseline, children older than 12 months had significantly lower height-for-age (HAZ) and weight-for-age (WAZ) scores, as well as higher rates of stunting and wasting, compared to younger children. …”
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Incompatible Aedes aegypti male releases as an intervention to reduce mosquito population-A field trial in Puerto Rico. by Liliana Sánchez-González, Jacob E Crawford, Laura E Adams, Grayson Brown, Kyle R Ryff, Mark Delorey, Jose Ruiz-Valcarcel, Nicole Nazario, Nexilianne Borrero, Julieanne Miranda, Sara N Mitchell, Paul I Howell, Johanna R Ohm, Charlie Behling, Brian Wasson, Craig Eldershaw, Bradley J White, Vanessa Rivera-Amill, Roberto Barrera, Gabriela Paz-Bailey

“…However, mark-release-recapture assessments suggest that male daily survival rates in the field may have been significantly impacted. …”
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Continuous aspirin treatment improves cardiovascular events and all-cause mortality in hemodialysis patients with peripheral artery disease by Chung-Kuan Wu, Noi Yar, Yun-Yi Chen

“…Kaplan–Meier analysis revealed that event-free rates of PTA, cardiovascular events, and all-cause mortality of patients with high MPR and continuous aspirin treatment were the highest among the three groups (p < 0.05).Conclusion Among HD patients with PAD, high MPR and continuous aspirin use significantly reduced the risk of PTA, surgical bypass, cardiovascular events, and all-cause mortality and improved the event-free rates of PTA, cardiovascular events, and all-cause mortality during long-term follow-up.…”
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Global burden and risk factors of childhood cardiovascular disease (1990–2021) by Caixia Hou, Nan Zhang, Chao Liu, Weijun Gao

“…Gender and age analyses revealed higher incidence and mortality rates among female children compared to males, with the 10–14 age group being the most affected. …”
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Application of Array Imaging Algorithms for Water Holdup Measurement in Gas–Water Two-Phase Flow Within Horizontal Wells by Haimin Guo, Ao Li, Yongtuo Sun, Liangliang Yu, Wenfeng Peng, Mingyu Ouyang, Dudu Wang, Yuqing Guo

“…An array capacitance arraay tool (CAT) was employed to measure water holdup under varying total flow rates and water cuts in a horizontal well experimental setup. …”
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Artificial intelligence-based prediction of treatment failure and medication non-adherence in overactive bladder management by Mert Başaranoğlu, İsa Kamil Taşdemir, Erdem Akbay, Hasan Erdal Doruk

“…Key predictive factors included early changes in bladder wall thickness (OR: 3.82, 95% CI: 2.14–6.81), diabetes duration > 7 years (OR: 2.73, 95% CI: 1.58–4.72), and urgency improvement < 25% (OR: 2.94, 95% CI: 1.76–4.92). Treatment failure rates varied significantly among pathological subgroups, with highest rates in diabetic neuropathy (42.8%) and lowest in idiopathic OAB (28.6%, p = 0.024). …”
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Natural Occlusion-Based Backdoor Attacks: A Novel Approach to Compromising Pedestrian Detectors by Qiong Li, Yalun Wu, Qihuan Li, Xiaoshu Cui, Yuanwan Chen, Xiaolin Chang, Jiqiang Liu, Wenjia Niu

“…Through ablation studies, we further investigate the impact of key parameters such as trigger patterns and poisoning rates on attack effectiveness. …”
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Global, regional, and national burden of endocarditis, 1990−2021: a systematic analysis of the GBD 2021 study by Ji Feng, Peng Liu, Hailong Li, Hong Chen, Qiwei Shen, Hualong Liu, Jinzhu Hu

“…Conversely, age-standardized rates declined (EAPCs: -0.58 for prevalence, -0.09 for incidence, -0.33 for DALYs, -0.29 for Deaths). …”
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Utility of Nasal Debridement Following Pediatric Functional Endoscopic Sinus Surgery: A Scoping Review by Jeeho D. Kim, Bastien A. Valencia-Sanchez, Beau Hsia, Saif A. Alshaka, Gabriel Bitar, Vijay A. Patel

“…The most common indication for FESS was chronic rhinosinusitis or recurrent sinus infections while that for SLED under general anesthesia varied from institutional practice patterns to surgeon preference. No meaningful comparison of outcomes was possible as the “success rates” of FESS with or without SLED were largely based on unvalidated questionnaires and equally subjective surgeon assessments. …”
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