The alteration of the sensorimotor network in trigeminal neuralgia after microvascular decompression surgery: a follow-up study using independent component analysis by Yan Zhang, Yan Zhang, Xueju Wang, Xuefeng Wang, Gengdi Huang

“…Group ICA was used to identify ROIs and assessed inter-group differences in neural activity using false discovery rate (FDR) correction.ResultsCompared to the HC, increased activity was observed in the right frontal operculum cortex, right insular cortex, right inferior frontal gyrus (pars opercularis), and right frontal pole in TN patients. …”
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Immune-related adverse events of neoadjuvant immunotherapy in patients with perioperative cancer: a machine-learning-driven, decade-long informatics investigation by Yuan Meng, Rong Hu, Song-Bin Guo, Deng-Yao Liu, Zhen-Zhong Zhou, Hai-Long Li, Wei-Juan Huang, Xiao-Peng Tian

“…During the past decade, the amount of research in the field of NAI safety has displayed a positive trend (annual growth rate: 30.2%), and it has achieved good global collaboration (international coauthorship: 17.43%). …”
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Clinico-epidemiological and immunological characteristics of rickettsioses in a Sri Lankan patient cohort 2018–2023 by Nayana Gunathilaka, Nilmini Chandrasena, Hemantha Sudusinghe, Vidusha Nethsara Mudalpath, Deshaka Jayakody, Ranjan Premaratna

“…Understanding epidemiological patterns and clinical manifestations is crucial for developing effective surveillance and prevention strategies. …”
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Bacterial isolates and antibiotic resistance in critically ill sepsis patients at a tertiary hospital in Ethiopia by Girum Tesfaye Kiya, Zeleke Mekonnen, Elsah Tegene Asefa, Esayas Kebede Gudina, Hanan Ahmed, Getenet Beyene, Mekidim Mekonnen, Gemeda Abebe

“…Results Bacterial pathogens were isolated from 33 patients, representing an isolation rate of 22.1% (95% CI: 16.2–29.6%). Gram-negative bacteria (GNB) accounted for the majority of the isolates, 25/33 (75.8%), with Escherichia coli, 6/25 (24%) being the predominant species. …”
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Watching live performances enhances subjective and physiological emotional responses compared to viewing the same performance on screen by Damien Gabriel, Julie Devos, Sandrine Chapuis, Alexandre Comte, Pierre-Edouard Billot

“…Heart rate increased with musical intensity in both conditions, while EEG data showed reduced arousal levels during the live performance, possibly reflecting deeper cognitive absorption. …”
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Impact of PM2.5 Exposure on Reproductive Health and Sperm Functions in Mice from a High-Pollution Industrial Environment by Fu-Jen Cheng, Chung-Shin Yuan, Xin Chen, Yu-Sheng Lin, Ping-Hsun Wu, Ping-Chi Hsu

“…Results Exposure to WS-PM2.5 and WI-PM2.5 reduced rates of normal sperm morphology, with each also presenting unique toxic effects. …”
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Investigation of corrosion void formation in a Ni-based alloy under simulated MSW incineration condition by Xinxin Wu, Terrence Wenga, Wenchao Ma

“…Therefore, in this study, corrosion void formation and migration mechanism on a newly designed alloy (Ni–28Cr–13Al–5W-0.06B-0.005C) was investigated and the corrosion rate of the alloy was compared with that of Ni–20Cr alloy under simulated municipal solid waste (MSW) incineration conditions at 600 °C. …”
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Interplay between C-reactive protein responses and antibiotic prescribing in people with suspected infection by Qingze Gu, Kevin Yuan, Jia Wei, Chang Ho Yoon, Anders Skyrud Danielsen, Augustine Luk, David W. Eyre, A. Sarah Walker

“…Here we investigated the association between serial CRP percentile changes, antibiotic prescribing patterns, and patient outcomes in a large cohort with suspected infection, acknowledging that CRP is one of multiple factors in clinical decision-making. …”
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Artificial slope deformation monitoring and analyzing based on SBAS technology by Xiaochuan Huang, Xiaochuan Huang, Xiaochuan Huang, Jincang Liu, Jincang Liu, Jincang Liu, Ting Yang, Ting Yang, Ting Yang, Yun Li, Yun Li, Yun Li, Lipeng Zhou, Lipeng Zhou, Lipeng Zhou

“…To address this gap, we employed the SBAS-InSAR methodology to analyze 44 Sentinel-1 SAR images spanning a highway slope region in Foshan City, Guangdong Province, integrating the slope’s construction timeline to temporally dissect deformation patterns and assess geological risks. Our results revealed a maximum annual average settlement rate of −35.69 mm/yr and a peak cumulative settlement of −28.9 mm, with deformation trends strongly correlated to construction phases—primarily concentrated between April 2022 and March 2023. …”
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Regional trends in perceptions of American Shoulder and Elbow Surgeons towards barriers to access for patients with Medicaid: limited perioperative service access, low patient enga... by Patrick Saunders, MD, Abhay Mathur, MD, Jordan Frausto, BA, Carlos D. Ramirez, BS, Adam Z. Khan, MD, Brad Bushnell, MD, Hafiz F. Kassam, MD

“…Results: A total of 257 (18.5% response rate) ASES members completed the survey. The mean year in practice for respondents was 14. …”
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Predominance of gram-negative multidrug-resistant pathogens causing lower respiratory tract infections among gene X-pert negative presumptive tuberculosis patients in Dar Es Salaam... by Irene Rabiel, Mtebe Majigo, Loveness Urio, Lilian Nkinda, Peter Richard Torokaa, Elieshiupendo M. Niccodem, Mabula Kasubi, Doreen Kamori, Joel Manyahi, Agricola Joachim

“…MTB was detected only in high‑quality sputum samples. The high resistance rate to commonly prescribed antibiotics for LRTIs called for further large-scale studies to guide and/or refine treatment guidelines and optimize patient care.…”
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Lipidomic analyses reveal the dysregulation of oxidized fatty acids (OxFAs) and acyl-carnitines (CARs) in major depressive disorder: a case-control study by Lei He, Na Duan, Chong Wang, Ru Shan, Jing Li, Lin Wang, Qiuli Liu, Junwei Tao, Li Liu, Xiaoliang Ma, Bing Cao

“…Results Based on the filtering criteria of false discovery rate (FDR) -adjusted P < 0.05, variable importance in projection (VIP) > 1.5, and fold change (FC) > 2.0 or < 0.5, a total of 40 lipids were identified as significantly different. …”
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Tracking Pelagia noctiluca scyphomedusae by combining modeling and stable isotope approaches by Isabella D’Ambra, Isabella D’Ambra, Simona Saviano, Maria Assunta Ambrosio, Vincenzo Botte, Daniele Iudicone, Maria Grazia Mazzocchi, Louise Merquiol, Louise Merquiol, Louise Merquiol, Daniela Cianelli

“…Simulations indicated that surface circulation patterns promoted the permanence of medusae within the coastal area, particularly in summer. …”
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GPC3: a novel mutated gene in pleuropulmonary blastoma by Jiahang Zeng, Xinying Wang, Yingyi Xu, Qinglin Yang, Junzheng Peng, Fenghua Wang, Jue Tang, Dongmei Huang, Jiachi Liao, Yunyu He, Lin Huang, Jianhua Liang, Le Li, Zefeng Lin

“…Survival analysis revealed that patients with high GPC3 expression (GPC3+++) exhibited a markedly lower two-year survival rate (30%) compared to moderate (GPC3++, 75%) and low (GPC3+, 90.9%) expression groups (p = 0.0035). …”
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Recursive Class Connectivity Classification (R3C) Applied to Binary Image Segmentation for Improved Infant Fingerprint Enhancement by Joao Leonardo Harres Dall Agnol, Luiz Fernando Puttow Southier, Jefferson Tales Oliva, Marcelo Teixeira, Rodrigo Minetto, Marcelo Filipak, Dalcimar Casanova, Erick Oliveira Rodrigues

“…Consequently, identification rates for children remain significantly lower than those achieved with adult fingerprints. …”
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Adipose-derived mesenchymal stem cell-supported ciprofloxacin therapy effectively protects the kidney parenchyma and functional integrity against acute pyelonephritis damage in rod... by Chih-Chao Yang, Ya Yue, Pei-Lin Shao, Ben-Chung Cheng, Tsuen-Wei Hsu, Yi-Ling Chen, Sheung-Fat Ko, Hon-Kan Yip, Mel S. Lee

“…The in vivo results revealed that the day-5 mortality rate and creatinine levels at days 2 and 5 were significantly greater in group 2 than in groups 1 and 5 ( P = 0.01), whereas the kidney injury score and inflammatory cell infiltration in the kidney were highest in group 2, lowest in group 1, and significantly greater in groups 3 and 4 than in group 5; however, there was no difference between groups 3 and 4 (all P < 0.0001). …”
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Risk of Incidence and Lethality by Etiology of Severe Acute Respiratory Syndrome in Hospitalized Children Under 1 Year of Age in Brazil in 2024: A Cross-Sectional Study by Tamires de Nazaré Soares, Natasha Cristina Oliveira Andrade, Suziane do Socorro dos Santos, Marcela Raíssa Asevedo Dergan, Karina Faine Freitas Takeda, Jully Greyce Freitas de Paula Ramalho, Luany Rafaele da Conceição Cruz, Perla Katheleen Valente Corrêa, Marli de Oliveira Almeida, Joyce dos Santos Freitas, Wilker Alves Silva, Marcos Jessé Abrahão Silva, Daniele Melo Sardinha, Luana Nepomuceno Gondim Costa Lima

“…Distribution by final classification and epidemiological week (EW) was analyzed; the incidence rate by Federative Unit (FU) (cases/100,000 < 1 year) with risk classification (Low/Moderate/High) was assessed; and, for cases with positive viral RT-PCR, the etiological frequency and virus-specific lethality rate (deaths/total cases of etiology ×100), also with risk classification, were extracted. …”
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Multimodal analysis of cell-free DNA enhances differentiation of early-stage breast cancer from benign lesions and healthy individuals by Thi Tuong Vi Van, Trung Hieu Tran, Thi Hue Hanh Nguyen, Van Thien Chi Nguyen, Dac Ho Vo, Giang Thi Huong Nguyen, Trong Hieu Nguyen, Kim Sang To, Anh Luan Nguyen, Cao Hong An Tran, Thanh Xuan Jasmine, Thi Loan Vo, Thi Huong Thoang Nai, Thuy Trang Tran, My Hoang Truong, Ngan Chau Tran, Thi Loc Le, Thi Hong Nhung Nguyen, Ngoc Hieu Tu, Thanh Son Tran, Bao Toan Le, Van Phong Tang, Pham Thanh Nhan Nguyen, Khac Tien Nguyen, Van Chien Ho, Xuan Vinh Nguyen, Nhu Nhat Tan Doan, Thi Trang Tran, Thi Minh Thu Tran, Vu Uyen Tran, Minh Phong Le, Thi Luyen Vu, Ba Linh Tieu, Huu Tam Phuc Nguyen, Luu Hong Dang Nguyen, Ngoc Minh Phan, Thi Van Phan, Thi Thanh Thuy Do, Thi Huyen Dao, Hung Sang Tang, Duy Sinh Nguyen, Hoa Giang, Minh Duy Phan, Hoai-Nghia Nguyen, Duc Hieu Vo, Le Son Tran

“…Conclusions These findings underscore the potential of cfDNA biomarkers to enhance BC detection and reduce the rate of unnecessary biopsies.…”
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Revealing the effect of layer-varying deposition strategy on laser-directed energy deposition bionic gradient NiTi alloy by Zhongxiong Kang, Chaorui Jiang, Mengqi Liu, Zhihui Zhang, Jie Zhao

“…The strategy includes different process parameters (the laser power and scanning speed), the scanning paths (alternative optimised spiral pattern, x-axis rotation pattern, and arc alternative pattern) and interlayer interval time. …”
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Optimization of ivacaftor-loaded solid lipid nanoparticles for solubility enhancement by Akshay Parihar, Akshay Parihar, Bhupendra G. Prajapati, Bhupendra G. Prajapati, Bhupendra G. Prajapati, Himanshu Paliwal

“…The in vitro dissolution study showed improved release pattern from the optimized formulation and release profile followed first-order model indicating a sustained release pattern from lipid matrix.ConclusionThis delivery system presented development of stable nanoparticle formulation exhibiting sustained release pattern, which may contribute to therapeutic outcomes in comparison with drug alone. …”
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