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4321
Relevance of Cellular Homeostasis-Related Gene Expression Signatures in Distinct Molecular Subtypes of Breast Cancer
Published 2025-04-01“…This study aimed to identify the gene expression patterns and biomarkers associated with breast cancer risk and progression by integrating transcriptomic and clinical data. …”
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4322
Multi-omics derivation of a core gene signature for predicting therapeutic response and characterizing immune dysregulation in inflammatory bowel disease
Published 2025-07-01“…Nomogram-based risk stratification effectively predicted biologic treatment responses across multiple therapeutic classes using four independent treatment datasets (GSE16879, GSE92415, GSE73661, GSE206285): low-risk patients demonstrated superior response rates to golimumab (63.3%), infliximab (54.8%), and vedolizumab (29% vs. 15% in high-risk group). …”
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4323
Study of the clinical profile of community-acquired pneumonia: a cross-sectional study in northeast India
Published 2025-06-01“…Alarmingly, high resistance rates were observed for widely used antibiotics such as ceftriaxone and cefuroxime, while meropenem, amikacin, and ertapenem retained high sensitivity. …”
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4324
Invasive meningococcal disease in South-Eastern European countries: Do we need to revise vaccination strategies?
Published 2024-12-01“…The incidence of IMD across Europe has been relatively low over the past decade; of the countries that came together for the South-Eastern Meningococcal Advocacy Group, the notification rates were lower than the European average for some country. …”
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4325
Epidemiologic Characteristics of Chronic Hepatitis B and Coinfections with Hepatitis C Virus or Human Immunodeficiency Virus in South Korea: A Nationwide Claims-Based Study Using t...
Published 2025-07-01“…Patients with HBV/HCV coinfection were older and had significantly higher rates of hypertension, diabetes, dyslipidemia, and major adverse liver outcomes, including hepatocellular carcinoma and liver transplantation, compared to other groups. …”
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4326
NDL-Net: A Hybrid Deep Learning Framework for Diagnosing Neonatal Respiratory Distress Syndrome From Chest X-Rays
Published 2025-01-01“…The model's low false negative and false positive rates underscore its superior diagnostic capabilities. …”
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4327
Genomic Evolution of White Spot Syndrome Virus in Shrimp: Insights from Transposon Dynamics
Published 2025-06-01“…White spot syndrome virus (WSSV) has emerged as a significant threat to global shrimp aquaculture, causing economic losses because of its rapid spread and high mortality rates. This study aims to elucidate the genetic and evolutionary dynamics of WSSV through a comprehensive genome analysis. …”
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4328
Analysis of 1560 Inpatient and Outpatient Escherichia coli Isolates from across Canada—Results from the CANWARD 2007 Study
Published 2009-01-01“…Fluoroquinolones and sulfonamides should be used cautiously and in consideration of local resistance patterns for infections caused by E coli, due to lower susceptibility rates. …”
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4329
Scalability analysis of heavy-duty gas turbines using data-driven machine learning
Published 2025-04-01“…The ML model, trained on data from various operating conditions and performance parameters, aims to uncover intricate relationships and patterns, resembling GT characteristics at different scales (ratings). …”
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4330
Consensus-Driven Development of an Exercise Base Manual Programme for Prediabetic Patients: A Delphi Study
Published 2025-05-01“…Initial recommendations were rated by panalists through a 5-point Likert scale. …”
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4331
Differential inhibitory effects of endocannabinoids on neuronal firing of mouse meningeal afferents
Published 2025-05-01“…Cluster analysis revealed that the transient activation by AEA involved fibers with small-amplitude spikes fired at rates of 1–2 Hz, whereas the persistently suppressed fibers consisted of high-amplitude spikes fired at rates exceeding 10 Hz. …”
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4332
TRNSYS-Based Performance Study of Solar-Assisted Single-Effect Absorption Cooling in Peshawar, Pakistan
Published 2025-06-01“…Under variable load conditions, the auxiliary heater responded through frequent pulsed flow patterns, achieving peak flow rates up to 49,000 kg/hr without compromising outlet temperature. …”
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4333
High prevalence of penicillin-resistant group B Streptococcus among pregnant women in Northwest Ethiopia
Published 2025-08-01“…In Ethiopia, reported GBS colonization rates among pregnant women range from 7.2 to 25.5%. …”
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4334
Male Date Palm Chlorotype Selection Based on Fertility, Metaxenia, and Transcription Aspects
Published 2025-07-01“…Pollen viability varied significantly among cultivars, with P8 and B25 exhibiting the highest germination rates and pollen tube elongation, while C22 showed the lowest. …”
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4335
Malaria morbidity, mortality and associated costs in Indonesia: analysis of the National Health Insurance claim dataset
Published 2025-05-01“…Patients’ sociodemographic status, repeated presentations to healthcare facilities, referral patterns and costs of treatment for the hospital settings were assessed by malaria species. …”
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4336
A nationwide population-based cross-sectional time series study of hospitalized chronic liver disease burden in Thailand from 2017 to 2022
Published 2025-08-01“…Age- and sex-standardized incidence and mortality rates were assessed through descriptive and trend analyses, with LOESS smoothing applied to identify temporal patterns. …”
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4337
Normotensive trauma patients with renal injuries: Hidden candidates for massive transfusion
Published 2025-06-01“…Among MT patients, those with initial SBP ≥ 90 mmHg (n = 170) showed significantly higher rates of renal injuries (8.8% vs. 1.4%, p = 0.035) compared to those with SBP < 90 mmHg (n = 71). …”
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4338
Emerging Threat of Multidrug-resistant Bacteria – An Experience from a Neonatal Intensive Care Unit of a Tertiary Care Hospital
Published 2025-06-01“…Multidrug-resistant (MDR) microorganisms that cause septicemia are responsible for high morbidity and mortality rates among patients in extreme age groups and pose serious treatment challenges despite multipronged measures. …”
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4339
Burden and inequalities of chronic kidney disease attributable to diet globally, regionally and temporally, 1990–2021
Published 2025-06-01“…However, significant regional variations were observed in these rates, with Central Sub-Saharan Africa experiencing the highest and Eastern Europe the lowest. …”
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4340
The administration sequences of immune checkpoint inhibitors and chemotherapy cause discrete efficacy when treating non-small cell lung cancer: a retrospective study
Published 2025-04-01“…Additionally, the objective response rates (ORRs) for the three groups were 55.82% (72/129), 58.21% (39/67), and 68.92% (51/74), respectively. …”
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