Characterization and dissolution test of recrystallized mefenamic acid by fast cooling methods by La Ode Akbar Rasydy, Hilda Damayanti, Erza Satrio, Jaka Supriyanta

“…Mefenamic acid, classified as a Biopharmaceutics Classification System (BCS) Class II drug, exhibits high permeability but low dissolution rates, limiting its bioavailability. This study aims to enhance the dissolution rate of mefenamic acid through crystal structure modification using fast cooling recrystallization with three distinct solvents: acetone (AMA), ether (AMEt), and ethyl acetate (AME). …”
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Short-term physiological responses of Pinus koraiensis Siebold & Zucc. and Chamaecyparis obtusa (Siebold & Zucc.) Endl. seedlings to elevated CO2 by Iereh Kim, Myeongja Kwak, Juyeong Kim, Suyoung Woo

“…C. obtusa initiated early biochemical adjustments, indicated by increased biochemical parameters of photosynthesis (maximum carboxylation rate, Vcmax; electron transport capacity, Jmax; and triose phosphate utilization, TPU), yet required more time for these changes to result in higher photosynthetic rates. …”
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Geographic distribution and trends of small-area burn claims in Japan: An analysis using NDB open data from 2014 to 2021 by Takeshi Utsunomiya, Takahiro Ueda

“…Introduction Burns are a major global health issue, causing approximately 180,000 deaths annually and leading to high morbidity rates. The Japan Trauma Data Bank Report 2022 recorded 1749 burn cases, with a mortality rate of 17.6%. …”
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Impact of Sex and Age on Trends of Mortality From Infective Endocarditis in High-Income Countries by Makoto Hibino, MD, MPH, PhD, Hiroki A. Ueyama, MD, Raj Verma, Hwee Teoh, PhD, Bobby Yanagawa, MD, PhD, Deepak L. Bhatt, MD, MPH, MBA, Subodh Verma, MD, PhD

“…Conclusions: Mortality rate from infective endocarditis is increasing in most countries, with varying patterns and degrees of changes observed in relation to sex and age. …”
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Evaluating anti-MRSA antibiotic stewardship with a focus on trends in consumption and resistance in a tertiary hospital in Alexandria, Egypt from 2019 to 2023 by Ehab Elmongui, Adel Zaki, Amel Elsheredy, Asmaa Abd Elhameed

“…The study compared these consumption patterns with resistance rates in Staphylococcus spp., including MRSS, from January 2020 to December 2023. …”
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The evolution of irreversible cell differentiation under cell death effect. by Yuanxiao Gao, Xueyan Zhao, Caixia Li

“…We show that irreversible differentiation is more likely to occur when cell death rates between cell types are linear. Meanwhile, differences in death rates between cell types affect the emergence conditions of irreversible differentiation, whereas no significant impacts on that from equal cell death rates. …”
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Multiple bursts of speciation in Madagascar’s endangered lemurs by Kathryn M. Everson, Luca Pozzi, Meredith A. Barrett, Mary E. Blair, Mariah E. Donohue, Peter M. Kappeler, Andrew C. Kitchener, Alan R. Lemmon, Emily Moriarty Lemmon, Carlos J. Pavón-Vázquez, Ute Radespiel, Blanchard Randrianambinina, Rodin M. Rasoloarison, Solofonirina Rasoloharijaona, Christian Roos, Jordi Salmona, Anne D. Yoder, Rosana Zenil-Ferguson, Dietmar Zinner, David W. Weisrock

“…Our analyses reveal multiple bursts of diversification (without subsequent declines) that explain much of today’s lemur diversity. We also find higher rates of speciation in Madagascar’s lemurs compared to lorisiforms, and we demonstrate that the lemur clades with high diversification rates also have high rates of genomic introgression. …”
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Distribution and Antimicrobial Resistance Analysis of Blood Culture Isolates at a Chinese National Cardiovascular Regional Medical Center: A 7-Year Retrospective Study by Wang Q, Wu F, Li T

“…Among Staphylococcus isolates, methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant coagulase-negative Staphylococci (MRCNS) were identified at rates of 51.6% and 88.7%, respectively. The carbapenem resistance rates of K. pneumoniae and E. coli were 28.8% and 4.0%, respectively. …”
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Distributed Robust Low-Carbon Economic Dispatch of Power Systems Considering Extreme Scenarios by HU Heng, QIN Jianru, LI Haibo, LIU Jiefeng

“…Particularly， tail risks triggered by extreme weather and the dynamic mismatches between stochastic RE fluctuations and conventional unit regulation rates invalidate conventional deterministic scheduling models reliant on typical scenarios. …”
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Cancer Genetics in the Arab World by Waleed S. Al Amri PhD, Muna Al Jabri PhD, Aisha Al Abri MS, Thomas A. Hughes PhD

“…Cancer remains a major global health burden, with incidence rates rising globally. The Arab world, which is often regarded as an underrepresented population in literature, shows distinct patterns in cancer incidences, genetics, and outcomes in comparison with Western populations. …”
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Glucose‐Induced Developmental Dynamics: Understanding Male Prevalence in Early Mouse Embryo Stages by Fikri Ardhani, Asako Okamoto, Masayuki Shimada

“…Conclusions Glucose availability accelerated embryonic development and created sex‐specific patterns of developmental timing, with male embryos exhibiting faster progression rates, which might be associated with differential X‐linked PDHA1 metabolic gene expression during early mouse embryogenesis.…”
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Microsaccades and Visual-Spatial Working Memory by Joshua T. Gaunt, Bruce Bridgeman

“…Intervening tasks during the memory interval affected memory as well as microsaccade patterns. Average microsaccade rate peaks after appearance of a fixation cross at the start of a trial, and dips at cue onset and offset. …”
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Global Trajectories of Colorectal Cancer Burden From 1990 to 2021 and Projection to 2040 by Xiaolu Chen, Xuesi Dong, Yadi Zheng, Chenran Wang, Zilin Luo, Jiaxin Xie, Zeming Guo, Xiaoyue Shi, Xinyue Zhu, Yongjie Xu, Wei Cao, Fei Wang, Ni Li

“…Most countries showed slowly increasing incidence rates (49.0%, n = 100) and stable age‐standardized mortality rates (51.0%, n = 104). …”
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Study on temperature field characteristics of window glass unexposed surfaces under varying indoor fire source conditions by Zhihan Li, Guowei Zhang, Longfei Yu, Yinxin Qu, Xiangfei Liu

“…Increased HRR amplified spatial disparities in warming rate increments while these disparities escalated proportionally with fire intensity. …”
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WINDII airglow observations of wave superposition and the possible association with historical “bright nights” by G. G. Shepherd, Y.‐M. Cho

“…The pattern generally appears as a combination of zonal waves 1, 2, 3, and 4 whose phases propagate at different rates. …”
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Mapping the mismatch between building and population growth: A global study of 1,700 cities by Siwei Lou, Yu Huang, Yukai Zou, Dawei Xia

“…Summary: The proportionality between urban building expansion and population growth is a key indicator of sustainable development, yet its global patterns and drivers remain underexplored. This study investigates the discrepancies between building volume and population growth rates (ΔR) across 1,744 cities in 12 major global economies from 2000 to 2020 using satellite-based building volume and population databases. …”
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Epidemiology and temporal trends of childhood type 1 diabetes in China: an analysis of the GBD 2021 by Feng Jin, Limin Xie, Guocheng Wang, Yu Pan, Cuijia Wang, Wei Li, Wei Li, Wei Li, Wei Li

“…Joinpoint regression analysis was applied to evaluate changes in incidence and mortality rates from 1990 to 2021, complemented by autoregressive integrated moving average (ARIMA) and exponential smoothing state space (ETS) models to project disease trends through 2040.ResultsThe results indicate a rising trend in the incidence of childhood T1D among Chinese children aged 0-14 years, alongside an overall decline in mortality, reflecting an epidemiological pattern characterized by low incidence yet non-negligible mortality. …”
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A Comprehensive Review of the Implementation and Impact of Nikshay Poshan Yojana in India’s National Tuberculosis Elimination Programme by Sethuraman Sivaraman, Saurabh Kumar Banerjee

“…Key aspects analysed include coverage and enrolment rates, disbursement processes, awareness and utilisation patterns, implementation challenges, and the scheme’s impact on treatment outcomes and nutritional status. …”
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Indirect exposure to insect growth disruptors affects honey bee (Apis mellifera) reproductive behaviors and ovarian protein expression. by Julia D Fine, Leonard J Foster, Alison McAfee

“…Curiously, eggs laid by queens exposed to pyriproxyfen exhibited increased hatching rates, and those larvae developed into worker progeny with increased responsiveness to their queens. …”
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Endoscopic endonasal approaches for resection of suprasellar pituitary neuroendocrine tumors: a novel classification based on the optic chiasm and operative nuances by Xuechao Wu, Cuiping Sun, Wei Tian, Zhongyuan Bao, Hongwei Gao, Jing Wang, Xiaojie Lu, Qing Wang

“…Conclusion The classification of suprasellar PitNETs into four types based on their relationship with the optic chiasm enhances our understanding of tumor growth patterns and aids in preoperative assessment. Consequently, determining individualized surgical strategies using EEAs for suprasellar PitNETs can lead to higher resection rates and better visual outcomes.…”
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