Lipid-lowering therapy in patients with coronary artery disease in primary care practices: what has changed over 7 years? by S. K. Zyryanov, S. B. Fitilev, A. V. Vozzhaev, I. I. Shkrebneva, D. A. Klyuev, L. N. Stepanyan, A. A. Danilova, A. T. Tsai, N. N. Landyshev, Ya. G. Voronko

“…Overall LLT prescription rate in outpatients with SCAD increased from 48,5 up to 86,4% (p<0,05) over the 7-year period. …”
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Molecular mechanism and biological pathway of high-expressed RAD51 in regulating cell adhesion and potentially affecting oral squamous cell carcinoma by Yu-Xing Tang, Yu-Yan Pang, Yan Cui, Guo-Jiao Wu, Lin-Qing Huang, Chang-Zhan Zhou, Bin Li, Qi Li, Bang-Teng Chi, Rong-Quan He, Di-Yuan Qin, Jian-Di Li, Gang Chen, Dong-Ming Li, Yi-Wu Dang

“…Abstract Background Oral squamous cell carcinoma (OSCC) is the most common malignant tumor in the oral cavity, with over 70% of cases detected in advanced stages and a 5-year survival rate of 50%. RAD51, a crucial DNA repair molecule, has also been implicated in the regulation of cell adhesion. …”
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Enhancing the accuracy of mental health assessments through the integration of self-report and objective measures: A convergence study utilizing biosignals and 14-day wearable data by Nayeon Kwon, Dongwon Lee, Soree Hwang, Soomin Yang, Inchan Youn, Hyuk-June Moon, Sungmin Han

“…Participants performed a laboratory-based mental arithmetic task designed to induce acute stress while their electrocardiogram (ECG) was recorded to extract heart rate variability (HRV) features. Additionally, they wore a smartwatch for 14 consecutive days to monitor stress levels multiple times daily, as well as continuous sleep and activity patterns. …”
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Identification of galectin-9 and its antibacterial function in Yellow River carp (Cyprinus carpio haematopterus) by Li Wang, Li Wang, Li Wang, Yuanyuan Hu, Xudong Li, Ziyan Zhang, Nan Wang, Limin Chao, Chengfei Li, Pei Gao, Jinyou Ma, Jinyou Ma, Lei Wang, Xiaojing Xia, Xiaojing Xia

“…IntroductionGalectin-9 is a β-galactoside-binding lectin that functions as a critical pattern recognition receptor (PRR) in the host immune system, initiating immune defense responses by recognizing and binding to pathogen-associated molecular patterns (PAMPs) on the surface of microorganisms. …”
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Individualized Estimation of Baseline Retinal Nerve Fiber Layer Thickness Using Conditional Variational Autoencoder by Ou Tan, PhD, Keke Liu, MD, Aiyin Chen, MD, Dongseok Choi, PhD, Jonathan C.H. Chan, MD, Bonnie N.K. Choy, MD, Kendrick C. Shih, MD, Jasper K.W. Wong, MD, Alex L.K. Ng, MD, Janice J.C. Cheung, MD, Michael Y. Ni, MD, Jimmy S.M. Lai, MD, Gabriel M. Leung, MD, Ian Y.H. Wong, MD, David Huang, MD, PhD

“…Compared with the population means, both DL models significantly reduced the prediction error for overall and quadrant NFLT and decreased the false-positive rate of identifying abnormal NFLT thinning in both myopia groups (from 13.0%-27.0% to 6.3%∼9.4%). …”
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High-Pressure Cylinder Failure under Fire Conditions – Investigation of the Consequences by Vojtech Jankuj, Petr Lepik, Miroslav Mynarz, Stefan Spitzer, Ales Bernatik

“…Hydrogen cylinders failed at pressures significantly lower than their rated destruction pressure due to thermal stress, generating fewer but substantial fragments and a fireball. …”
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Participatory Drawing Methodology for Light in Architecture: Drawing Experienced Space by Ulrika Wänström Lindh

“…Based on a study in which 16 participants’ experiences of different light scenarios were collected through sketches, semantic rating scales, and deep interviews, the participants drew the boundaries of what they experienced as “the room” and spatial directions inside it. …”
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Lumbar Temperature Map of Elderly Individuals with Chronic Low Back Pain—An Infrared Thermographic Analysis by Nelson Albuquerque, Liliana Gonçalves, Wally Strasse, Joaquim Gabriel, Laetitia Teixeira, Pedro Cantista

“…Pain intensity was measured using a numerical rating scale (0–10). The functional assessments included spine mobility tests and validated questionnaires evaluating clinical characteristics. …”
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The cost effectiveness of a multidomain intervention on physical, cognitive, vascular, dietary and psychosocial outcomes among community dwelling older adults with cognitive frailt... by Pavapriya Ponvel, Suzana Shahar, Devinder Kaur Ajit Singh, Arimi Fitri Mat Ludin, Ponnusamy Subramaniam, Norhayati Ibrahim, Hasnah Haron, Aniza Ismail, Chin Ai-Vyrn, Mazlyfarina Mohamad, Hidayah Fadzil, Norhayati Mustafa Khalid, A’isyah Mohammad Safien, Jamilah Mohammad Hanipah, Azyana Ibrahim, Jenni Lehtisalo, Miia Kivipelto, Francesca Mangialasche

“…Despite a 50% dropout rate, adherence among remaining participants was over 50% for all intervention components (range 53%-91%). …”
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Optimization of bovine oocyte cryopreservation: membrane fusion competence and cell death of linoleic acid-in vitro matured oocytes subjected to vitrification by Glenda L. Ríos, María Florencia Suqueli García, María Florencia Suqueli García, Rodrigo J. Manrique, Jorgelina Buschiazzo

“…Zona pellucida-free oocytes co-incubated with sperm demonstrated that 43 μM LA better preserved the original sperm adhesion and fusion pattern post-vitrification, although fertilization rate was not improved. …”
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Dynamic brain-heart-gut coupling during sleep: a continuous physiological signal analysis by Guojing Wang, Guojing Wang, Guojing Wang, Hongyun Liu, Hongyun Liu, Shijing Wu, Shijing Wu, Xiaohua Yu, Xiaohua Yu, Weidong Wang, Weidong Wang

“…In terms of heart-gut coupling (HGC), the coupling strength between the very low frequency (VLF) band of heart rate variability (HRV) and all BS-derived power sequences was significantly lower than other HRV frequency bands. …”
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Aberrant Histone Methylation in Patients with Graves’ Disease by Ni Yan, Kaida Mu, Xiao-fei An, Ling Li, Qiu Qin, Rong-hua Song, Qiu-ming Yao, Xiao-qing Shao, Jin-an Zhang

“…The rate (degree) of H3K4 and H3K9 methylation and the expressions of histone-modifying genes were investigated. …”
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Electrocardiographic Abnormalities in Cardiac Contusion: Experimental Study by O. V. Korpacheva, V. T. Dolgikh

“…An electrocardiogram, respiration rate, and left carotid blood pressure were recorded in the direct fashion. …”
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A bibliometric analysis of research trends in mesenchymal stem cell therapy for neonatal bronchopulmonary dysplasia: 2004–2024 by Lu Bai, Yue Xin

“…Time-series analysis revealed a significant acceleration in publication output after 2015 (p < 0.01), with a compound annual growth rate of 18.2%. The United States was the leading contributor (131 publications, 37.1%), followed by China (72 publications, 20.4%) and Canada (54 publications, 15.3%). …”
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Efficacy and Safety of Tofacitinib in Patients with Polymyalgia Rheumatica (EAST PMR): An open-label randomized controlled trial. by Xinlei Ma, Fan Yang, Jinzhi Wu, Bei Xu, Mengdi Jiang, Yiduo Sun, Chuanying Sun, Ye Yu, Danyi Xu, Lanlan Xiao, Chunyun Ren, Chunyan Chen, Zi Ye, Junyu Liang, Jin Lin, Weiqian Chen

“…Secondary endpoints: PMR-AS score, c-reactive protein (CRP), and erythrocyte sedimentation rate (ESR) at weeks 12 and 24. Thirty-nine patients with newly diagnosed PMR received tofacitinib, and 37 patients received glucocorticoid. …”
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Loss of Reduction in Pediatric Distal Radius Fractures: Risk Factors From a Prospective Multicenter Registry by Apurva S. Shah, MD, MBA, Zoe E. Belardo, BA, Mark L. Miller, MD, Michael C. Willey, MD, Susan T. Mahan, MD, MPH, Divya Talwar, PhD, MPH, Donald S. Bae, MD

“…The majority of subjects sustained bicortical metaphyseal distal radius fractures (68%), followed by Salter-Harris II physeal fractures (26%). The rate of radiographic LOR was 44% (271/616), and 11% (70/616) of fractures shifted ≥20°. …”
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Analysis of influencing factors for primary membranous nephropathy complicated with atherosclerotic cardiovascular disease and establishment of a nomogram prediction model by Mirixiatijiang· Maimaiti, Zhu Guo-qiang, Su Ming-jie, Halinuer· Shadekejiang, Zhang Xue-qin, Lu Chen

“…They also had significantly higher systolic blood pressure ［130（120， 142） mmHg（1 mmHg=0.133 kPa） <italic>vs</italic> 122.0（113.5， 135.5） mmHg］， higher diastolic blood pressure ［80 （75， 90） mmHg <italic>vs</italic> 80（70， 85.5） mmHg］， higher prevalence of hypertension［142（64.8%） <italic>vs</italic> 67 （32.7%）］， and higher proportion of manual workers［60（27.4%） <italic>vs</italic> 28（13.7%）］ Additionally， lymphocyte count （LYM）， platelet count （PLT）， blood sodium concentration （Na）， blood urea nitrogen （BUN）， blood creatinine （Cr）， estimated glomerular filtration rate （eGFR）， 24-hour quantitative urine protein， glutamic transaminase， urinary occult blood， number of urinary hyaline and pathological tubular patterns， C-reactive protein （CRP）， complement C4， plasma fibrinogen， D-dimer， and centrocyte-lymphocyte ratio were all significantly different between the two groups （<italic>P</italic>&lt;0.05）. …”
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A data-driven approach to forest health assessment through multivariate analysis and machine learning techniques by Raja Waqar Ahmed Khan, Hamayun Shaheen, Muhammad Ejaz Ul Islam Dar, Tariq Habib, Muhammad Manzoor, Syed Waseem Gillani, Abeer Al-Andal, John Oluwafemi Ayoola, Muhammad Waheed

“…RF-based feature importance analysis showed tree DBH, height, regeneration rate, soil erosion, and tree density as key ecological drivers of forest health. …”
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Digital learning resource use among Swedish medical students: insights from a nationwide survey by Martin F. Bjurström, Emma Lundkvist, Louise W. Sturesson, Ola Borgquist, Robin Lundén, Malin Jonsson Fagerlund, Miklós Lipcsey, Thomas Kander

“…Results One thousand seven hundred sixty-six students responded to the survey, with an average response rate of 20.2% across sites. The five most frequently used digital resources were (percentage using at least on a weekly basis): University study platform (75.3%), videos (68.0%), flashcards (66.4%), student notes (53.4%) and external study platforms (47.3%). …”
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Citronella oil-loaded electro-spun single and core-shell nano fibers as sustained repellent systems against Aedes aegypti by Samali Udara Liyanaarachchi, Sanjeewa K. Rodrigo, Nilwala Kottegoda, Veranja Karunaratne, Menaka Hapugoda, Tharaka Ranathunge, Lahiru Udayanga, Dushmantha Adikari

“…It was found that maintaining the outer:inner flow rate ratio at 5:2 in coaxial process is imperative to produce good fibers. …”
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