Loss of <i>Myostatin</i> Shapes the Transcriptomic and Epigenetic Landscapes Across Multiple Muscle Types in Cattle by Chao Hai, Xuefei Liu, Chunling Bai, Guanghua Su, Lei Yang, Guangpeng Li

“…The results showed that the <i>MSTN</i> gene-edited (MT) cattle skeletal muscle exhibited significantly larger myofiber cross-sectional areas (<i>p</i> = 0.049), accompanied by reduced shear force (<i>p</i> = 0.044), cooking loss rate (<i>p</i> = 0.0029), and pH (<i>p</i> = 0.014). …”
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A Lower Energy Balance is Associated With Higher Severity and Odd of Depression Based on the Beck Depression Inventory‐13 (BDI‐13) in a Retiring Age Population: A Population‐Based... by Mohammad Reza Shadmand Foumani Moghadam, Mostafa Shahraki Jazinaki, Zohre Hosseini, Fatemeh Rajabi, Sharif Etemdi, Melika Hadizadeh, Parnian Pezeshki, Mohammad Amushahi, Reza Rezvani

“…Energy balance was calculated by subtracting energy intake from Total Energy Expenditure (TEE) and Basal Metabolic Rate (BMR) which was calculated using Bio‐Electrical Impedance Analysis and Mifflin and St‐Jeor formula. …”
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Multivariate Evaluation of Flash Drought Across the United States by Jason A. Otkin, Yafang Zhong, Trent W. Ford, Martha C. Anderson, Christopher Hain, Andrew Hoell, Mark Svoboda, Hailan Wang

“…The FDII method uses the rate of intensification (FD‐INT) and subsequent drought severity (DRO‐SEV) to determine when a flash drought occurred and the strength of the event. …”
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Differential Cortical Responses of Functional and Sensory Electrical Stimulation in Closed-Loop Tremor Suppression for Parkinson&#x2019;s Disease by Xiaoqi Zhao, Tinglan Huang, Mengyue Jin, Hongbo Zhao, Yu Shi, Yanlin Wang, Xiao Shen, Zhen Li, Qingqing Shi, Xiaodong Zhu, Lin Meng

“…Both FES and SES significantly reduced tremor amplitude, with FES showing overall greater suppression (hand suppression rate: 60.72% vs. 48.31%, p &#x003E;0.05; forearm suppression rate: 62.25% vs. 54.41%, p &#x003E;0.05) where substantial inter-individual variability was observed. …”
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Timing of Surgery and Preoperative Predictors of Surgical Site Infections for Patients with Depressed Skull Fractures in a Sub-Saharan Tertiary Hospital: A Prospective Cohort Study by Hervé Monka Lekuya, Jelle Vandersteene, Larrey Kasereka Kamabu, Rose Nantambi, Ronald Mbiine, Anthony Kirabira, Fredrick Makumbi, Stephen Cose, David Patrick Kateete, Mark Kaddumukasa, Edward Baert, Moses Galukande, Jean-Pierre Okito Kalala

“…The group of surgical intervention >48 h had an increased incidence of SSI (57.3% vs. 42.7%, p = 0.006), a longer median of postoperative hospital stay (8[IQR = 6–12] days versus 5 [IQR = 4–9], [p < 0.001]), and a higher rate of reoperation (71.4% vs. 28.6%, p = 0.05) in comparison with the group of ≤48 h. …”
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Annual dialysis data report 2022, Japanese Society for Dialysis Therapy (JSDT) Renal Data Registry by Norio Hanafusa, Masanori Abe, Nobuhiko Joki, Junichi Hoshino, Masatomo Taniguchi, Kan Kikuchi, Takeshi Hasegawa, Shunsuke Goto, Tetsuya Ogawa, Eiichiro Kanda, Shigeru Nakai, Toshihide Naganuma, Kenichiro Miura, Atsushi Wada, Yoshiaki Takemoto

“…The number of chronic dialysis patients was 347,474 at the end of 2022, marking the first decrease since the beginning of this survey. The prevalence rate of dialysis patients was 2781 per million population. …”
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The role of city parks in creating ‘wellbeing societies’: A case study of Piłsudski Park in Łódź, Poland by Melanie Kay Smith, Joanna Kowalczyk-Anioł, Jakub Janiszewski, Karolina Grabarczyk

“…Although social interactions are rated lower overall, they are particularly significant for younger and older users, as well as marginalized groups such as unemployed individuals. …”
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Clinicopathological characterization of Switch/Sucrose-non-fermentable (Swi/Snf) complex (ARID1A, SMARCA2, SMARCA4)-deficient endocervical adenocarcinoma by Chao Cao, Zi-Yun Wu, Wei Liao, Li-Jun Wei, Hao-Yu Liang, Xia Yang, Rong-Zhen Luo, Li-Li Liu

“…Defining Swi/Snf deficiency as loss of any subunit, the overall deficiency rate was 5.96% (36/604). Swi/Snf-deficient ECA tended to advanced FIGO stage (III-IV, P = 0.041), larger tumor size (P < 0.001), deeper stromal invasion (≥ 1/3, P = 0.046), and higher lymph node metastasis rate (P = 0.037). …”
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Psychological, social factors, and smoking behavior mediated the effects of cannabis use on personality disorders: A Mendelian randomization study by Yao Ni, Juanmei Li, Zitian Tang, Youqian Zhang, Yanyan Feng

“…BackgroundRapid changes in attitudes, legality, and patterns of cannabis use (CU) underscore the importance of understanding its impact on mental health. …”
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Repurposing of CNS accumulating drugs Gemfibrozil and Doxylamine for enhanced sensitization of glioblastoma cells through modulation of autophagy by Smita Dey, Prerika Mathur, Sudeshna Mukherjee, Rajdeep Chowdhury, Syamantak Majumder, Aniruddha Roy, Shibasish Chowdhury

“…Abstract GBM is one of the most aggressive malignancies, having the greatest fatality rate and average life years lost. The current standard medicine, temozolomide (TMZ), is ineffective, requiring the development of new treatments. …”
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Cyclical short‐term fasting and refeeding effects on immunological alteration of the disk abalone, Haliotis discus discus by Dien Arista Anggorowati, Liqing Zang, Yutaka Tamaru, Takahiko Aoki, Fumiyoshi Okazaki

“…We measured survival and growth rate as well as analysed immunological parameters, such as total haemocyte count, phenoloxidase activity, respiratory burst activity, lysozyme activity and protein content across the groups. …”
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Different functions of PHF10 isoforms – subunits of the PBAF chromatin remodeling complex by A. A. Sheynov, V. V. Tatarskiy, A. M. Azieva, S. G. Georgieva, N. V. Soshnikova

“…Stability can alter the turnover rate of the subunits of the PBAF complex. All PHF10 isoforms are degraded by β-TrCP ubiquitin ligase but PHF10-S isoforms contain a cluster of serins (X-cluster) for multiple phosphorylation by casein kinase I. …”
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Parasitic infections and the development of endomyocardial fibrosis: systematic review of case reports and case series by Abel Aizeque, Alex Mwangi Kihunyu, Olamide Daniel Odusola, Sulymon A. Saka, Abdinasir Mohamed Aray

“…Treatment mainly consisted of antiparasitic therapy and diuretics, with a survival rate of 50%, while 19% (3/16) of patients died from multi-organ failure and thromboembolic complications. …”
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Geographical variation in antimicrobial use and multiresistant pathogens in Brazilian intensive care units: a nationwide study by Alice Ramos Oliveira Silva, Constanza Xavier Borges Barbosa, Raianne Soares Rebelo, Fernando Fernandez-Llimos, Elisangela Costa Lima

“…We measured antimicrobial use and CLABSI trends per ICU bed using the compound annual growth rate (CAGR). Results: we evaluated the regional variation in CLABSI by multidrug-resistant pathogens and the antimicrobial use in 1,836 hospital intensive care units (ICUs). …”
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Optimal Skin Prick Test Panel for Detecting Respiratory Allergens in Children: A Retrospective Study by Aykut Eşki, Gökçen Kartal Öztürk, Figen Gülen, Esen Demir

“…Different allergen sensitization patterns have been observed within countries and regions according to geographical and seasonal variations. …”
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Outlook for Neurofi bromatosis Type I Research in the Republic of Bashkortostan by R. N. Mustafin, E. K. Khusnutdinova

“…Average worldwide incidence rate of NF1 is 1:3000, equal in men and women. Th e disease develops with a heterozygous mutation in the oncosupressor neurofi bromin-encoding gene NF1. …”
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Clinical Features and Surgical Management of Bile Duct Cyst in Adults by Xin Wu, Binglu Li, Chaoji Zheng, Xiaodong He

“…There was no significant difference in the postoperative complication rate between the two groups. Ninety-four patients were followed up for 37.8±23.8 months, and BDI occurred in 33 patients (35.1%). …”
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Detection and genetic diversity of Neoehrlichia mikurensis in rodents from central and southern Shanxi, China by Hongbing Cheng, Jingrong Niu, Yiping Liu, Fei Ren, Chao Zhao, Jia Cui, Yuzan Bai, Yunxia Chen, Juan Yu, Huaxiang Rao

“…N. mikurensis was detected in Apodemus agrarius from Yangquan and Eothenomys inez from Yuncheng, with a positivity rate of 0.66% (2/301). Phylogenetic analysis based on 16 S rRNA and groEL genes revealed that the sequences in this study formed distinct branches separate from reported clusters (Clusters I-IV), clustered near Clusters III and IV, which the pathogenicity was unclear. …”
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Sex differences in DNA methylation variations according to ART conception-evidence from the Norwegian mother, father, and child cohort study by Dana Kristjansson, Yunsung Lee, Christian M. Page, Håkon Gjessing, Maria C. Magnus, Astanand Jugessur, Robert Lyle, Siri E. Håberg

“…We identified 37 differentially methylated CpGs according to ART-conception among girls, and 70 differentially methylated CpGs according to ART-conception among boys, when we used a 1% false discovery rate to account for multiple testing. Ten CpGs were differentially methylated according to conception by ART in both sexes. …”
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Effect of Basic Point-of-Care Ultrasound Course on Physicians’ Use in Clinical Practice: A Survey Study by Burcu Azapoğlu Kaymak, Merve Ekşioğlu, Özlem Dikme

“…Among 610 physicians with available contact information, 201 completed the electronic survey, resulting in a response rate of 33%. The survey assessed participants’ demographics, previous ultrasound training, and self-reported changes in POCUS usage before and after the course. …”
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