Lipid-lowering statins and polyphenol-based supplementation: a scoping review on drug-food interaction potential by Rita Costa, Rita Costa, Rita Costa, Rita Costa, Rita Costa, Carolina Ferreira, Carolina Ferreira, Carolina Ferreira, André Alves, André Alves, André Alves, Sara Nunes, Sara Nunes, Sara Nunes, Sara Nunes, Sara Nunes, Flávio Reis, Flávio Reis, Flávio Reis, João Malva, João Malva, João Malva, Sofia Viana, Sofia Viana, Sofia Viana, Sofia Viana, Sofia Viana

“…BackgroundLifestyle modifications, particularly the adoption of healthy dietary patterns such as the Mediterranean Diet (MedDiet), are foundational in any treatment plan, including for patients prescribed first-line statin therapy for hypercholesterolemia. …”
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Risk of Incidence and Lethality by Etiology of Severe Acute Respiratory Syndrome in Hospitalized Children Under 1 Year of Age in Brazil in 2024: A Cross-Sectional Study by Tamires de Nazaré Soares, Natasha Cristina Oliveira Andrade, Suziane do Socorro dos Santos, Marcela Raíssa Asevedo Dergan, Karina Faine Freitas Takeda, Jully Greyce Freitas de Paula Ramalho, Luany Rafaele da Conceição Cruz, Perla Katheleen Valente Corrêa, Marli de Oliveira Almeida, Joyce dos Santos Freitas, Wilker Alves Silva, Marcos Jessé Abrahão Silva, Daniele Melo Sardinha, Luana Nepomuceno Gondim Costa Lima

“…Distribution by final classification and epidemiological week (EW) was analyzed; the incidence rate by Federative Unit (FU) (cases/100,000 < 1 year) with risk classification (Low/Moderate/High) was assessed; and, for cases with positive viral RT-PCR, the etiological frequency and virus-specific lethality rate (deaths/total cases of etiology ×100), also with risk classification, were extracted. …”
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Risk of developing drug abuse in administration of a new hexaazaisowurtzitane derivative-based analgesic (experimental study) by S. G. Krylova, T. N. Pove’teva, K. A. Lopatina, Yu. V. Nesterova, E. P. Zueva, O. G. Afanas’eva, P. V. Kulpin, E. A. Kiseleva, N. I. Suslov, D. A. Kulagina, S. V. Sysolyatin, V. V. Zhdanov

“…Previous in vivo and in silico studies (docking, molecular modeling, molecular dynamics simulation) on the multi-target mechanism of thiowurtzine explain the absence of its morphine-like effect by the fact that the major targets of the analgesic are TRPA1 receptors and voltage-gated Ca 2+ channels. With a high degree of probability, the conclusions made herein predict no drug abuse development when thiowurtzine is used in the clinical setting. …”
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Genetic evolution, epidemic trends, and recombination dynamics of PRRSV-1 in China by Chengzhen Weng, Chengzhen Weng, Chengzhen Weng, Xinxin Huang, Xinxin Huang, Xinxin Huang, Zhian Chen, Zhian Chen, Minjia He, Minjia He, Minjia He, Beiwen Zhang, Beiwen Zhang, Beiwen Zhang, Hongxi Li, Hongxi Li, Hongxi Li, Jingrui Xie, Jingrui Xie, Meichun Chen, Meichun Chen, Meichun Chen, Longxin Qiu, Longxin Qiu, Xiaobing Li, Xiaobing Li, Chong Cao, Chong Cao, Hongbo Chen, Hongbo Chen

“…This study systematically investigated the epidemiological patterns, genetic evolution, recombination dynamics, GP5 genetic diversity, and N-glycosylation variants of PRRSV-1 strains circulating in China. …”
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Mental Health in the Age of Hyperconnectivity: A Crisis Hidden in Plain Sight by Sitara Ejaz, Hafiz Muhammad Haseeb Khaliq

“…Young people are experiencing increasing levels of anxiety, depression, and loneliness at an alarming rate. Serious damage to emotional health stems from the pervasive information overload and social envy people experience through their constant online connection 3. …”
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Shear Strength Characteristics of Soft Soil in Nansha District of Guangzhou by WANG Wei-qi, LIAN Chang-jiang, LI Jian-ping, CHEN Zhi-yong, CHENG Dong-hai, CAI Wei-long, TANG Kai, LI Chao

“…Certain anomalies and unconventional patterns are observed in the dataset, including the opposite variation trends in the consolidated quick shear strength of both silt and silty soil with increasing depth, as well as the difference in the rate of strength change for silt at depths of 10 m≤h&lt;20 m under consolidated quick shear compared to direct shear conditions. …”
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Distinct brain atrophy progression subtypes underlie phenoconversion in isolated REM sleep behaviour disorderResearch in context by Stephen Joza, Aline Delva, Christina Tremblay, Andrew Vo, Marie Filiatrault, Max Tweedale, Jean-François Gagnon, Ronald B. Postuma, Alain Dagher, Johannes Klein, Michele Hu, Petr Dusek, Stanislav Marecek, Zsoka Varga, John-Paul Taylor, John T. O'Brien, Michael Firbank, Alan Thomas, Paul C. Donaghy, Stéphane Lehéricy, Marie Vidailhet, Jean-Christophe Corvol, ICEBERG Study Group, Richard Camicioli, Howard Chertkow, Simon Lewis, Elie Matar, Kaylena A. Ehgoetz Martens, Lachlan Churchill, Michael Sommerauer, Sinah Röttgen, Per Borghammer, Karoline Knudsen, Allan K. Hansen, Dario Arnaldi, Beatrice Orso, Pietro Mattioli, Luca Roccatagliata, Oury Monchi, Shady Rahayel, Isabelle Arnulf, Samir Bekadar, Eve Benchetrit, Alexis Brice, Vanessa Brochard, Alizé Chalançon, Benoit Colsch, Florence Cormier-Dequaire, Jean-Christophe Corvol, Virginie Czernecki, Bertrand Degos, Cécile Delorme, Pauline Dodet, Carole Dongmo-Kenfack, Marie-Odile Habert, Farid Ichou, Jonas Ihle, Cécile Galléa, Rahul Gaurav, Marie-Alexandrine Glachant, Manon Gomes, David Grabli, Elodie Hainque, Laetitia Jeancolas, Christelle Laganot, Stéphane Lehéricy, Suzanne Lesage, Smaranda Leu-Semenescu, Richard Levy, Valentine Maheo, Graziella Mangone, Louise Laure Mariani, Aurelie Méneret, Poornima Menon, Fanny Mochel, Vincent Perlbarg, Dijana Petrovska, Fanny Pineau, Nadya Pyatigorskaya, Sophie Rivaud-Pechoux, Emmanuel Roze, Sara Sambin, Julie Socha, Arthur Tenenhaus, Romain Valabregue, Marie Vidailhet, Lydia Yahia-Cherif

“…Distinct brain atrophy patterns may already be seen in iRBD; however, how brain atrophy begins and progresses remains unclear. …”
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Dependence of Indicators of Daily Blood Pressure Monitoring on Activity of Pathological Process in Patients with Systemic Lupus Erythematosus by Abrahamovych O., Abrahamovych U., Kushyna A., Guta S., Synenkyi O.

“…According to the first goal was rated the BP in the SLE patients during the period of 24 hours, for which: a) were examined the average daily, maximum and minimum levels of systolic blood pressure (SBP), diastolic blood pressure (DBP), the average blood pressure; b) was analysed the daily index (DI) of SBP, DBP and the average blood pressure; c) was examined the time index (TI) of SBP, DBP and the average blood pressure. …”
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Melatonin regulated through GhTDC5 enhances tryptophan decarboxylase against drought stress in cotton by Xin Yu, Xiugui Chen, Ning Wang, Maohua Dai, Zhining Yang, Yapeng Fan, Yuping Sun, Xinrui Zhang, Ruize Song, Menghao Zhang, Hao Lan, Fange Wu, Hui Huang, Xiao Chen, Lidong Wang, Xuke Lu, Shuai Wang, Lixue Guo, Junjuan Wang, Lanjie Zhao, Keyun Feng, Jing Jiang, Wuwei Ye

“…Abstract Tryptophan decarboxylase (TDC) is the rate-limiting enzyme in the biosynthesis of melatonin and plays a crucial role in melatonin production in plants. …”
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The Analysis and Prioritization of Social Sustainability of Rural Environments (Case Study: Ghal’eh Biaban District Darab Sub-Province) by Saeid Reza Akbarian Ronizi, Rana Shaykh-Baygloo

“…B) Demographic, including components such as population density, change of population structure, migration patterns among village and city and cultural issues. …”
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A computational DNA methylation method to remove contaminated DNA from spent embryo culture medium for noninvasive preimplantation genetic testingResearch in context by Yidong Chen, Jin Huang, Fuchou Tang, Lu Wen, Jie Qiao

“…By testing simulated SECM samples, the method demonstrated a substantial reduction in the false-negative rate even with up to 75% cumulus cell contamination. …”
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Trypanosoma dionisii in China: ecology and tentative epidemiology by Qin Liu, Mu-xin Chen, Yu-chun Cai, Yuan-yuan Li, Zi-yi Wang, Yun-hai Guo, Yu-wan Hao, Jing-bo Xue, Yi-dan Jing, Fan-na Wei, Yong-bin Wang, Yue-jin Li, Hai-fang Wang, Jun-ling Sun, Ya-li Wang, Gang Wang, Na Wang, Nai-li Guo, Jian-cun Fang, Wei-xiao Chen, Xun-ming Zhou, Yang Yu, Yi Zhang, Jun-hu Chen, Qiang Wang, Shi-zhu Li, Ge Yan, Qun Li

“…It is important to improve our understanding of ecological and epidemiological patterns to identify potential transmission vectors and to estimate the risk of T. dionisii infection in the local population as well as in various species of domestic and wild animals. …”
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Characterizing Breast Tumor Heterogeneity Through IVIM-DWI Parameters and Signal Decay Analysis by Si-Wa Chan, Chun-An Lin, Yen-Chieh Ouyang, Guan-Yuan Chen, Chein-I Chang, Chin-Yao Lin, Chih-Chiang Hung, Chih-Yean Lum, Kuo-Chung Wang, Ming-Cheng Liu

“…Analysis of signal intensity decay curves generated from these parameters further illustrated distinct diffusion patterns and confirmed that high cellularity tumor regions showed greater water molecule confinement compared to low cellularity regions. …”
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Three-dimensional cell sheet model improves in vitro prediction accuracy of osteogenic potential for biodegradable magnesium-based metals by Liangwei Chen, Guanxi Wu, Siyu Liu, Ziyu Yan, Honglei Yue, Jianhua Zhu, Na Ge, Yifei Wang, Qingxiang Li, Guanqi Liu, Tingting Zhang, Haowen Zheng, Shaozhe Xin, Guangyunhao Sun, Chuanbin Guo, Jianmin Han

“…Flow cytometry showed higher Ki67 expression and lower ROS levels and apoptosis rate in cell sheets. ShRNA-mediated silencing of N-Cadherin in cell sheets significantly compromised their cytoprotective capacity against Mg metal-induced toxicity. …”
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Criminal Law Challenged by Crossing into Virtual Reality by Mahdi Karimi

“…This information includes behavioral patterns, interests, preferences, biometric and physiological data such as heart rate, body energy consumption, etc., which are comprehensively collected to create a complete and accurate user profile, potentially resulting in severe violations of users' mental privacy. …”
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Finger drawing on smartphone screens enables early Parkinson's disease detection through hybrid 1D-CNN and BiGRU deep learning architecture. by Zhaohui Zhu, E Wu, Pengfei Leng, Jiajun Sun, Mingming Ma, Zhigeng Pan

“…Our hybrid model combined multi-scale convolutional feature extraction (using parallel 1D-Convolutional branches) with bidirectional temporal pattern recognition (via gated recurrent unit [GRU] networks) to analyze movement abnormalities and detect the disease.…”
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Assessment of the functional state of left heart in patients with chronic heart failure with preserved ejection fraction by D. V. Vdovenko, R. A. Libis

“…All patients had the diastolic dysfunction: 60 patients had abnormal relaxation pattern, and 20 patients had pseudonormal pattern. …”
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Analysis of fibrous material deformation in the roll contact zone by Khurramov Shavkat, Abrorov Akbar, Abdullaev Akhror, Norov Nusiratjon, Baymatov Shakhriddin

“…The analytical description of the shape of contact curves and the thickness of processed material in the technological zone of a two-roll module in a dynamic mode is given, considering the deformation pattern of the processed material. It is determined that one of the factors that most influence the shape of the contact curve is the ratio of the compression rate of the coating deformation to the corresponding material feed rate. …”
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Influence of Water Injection Pressure on Methane Gas Displacement by Coal Seam Water Injection by Tianwei Shi, Yishan Pan, Wenhong Zheng, Aiwen Wang

“…It is of great significance to study the pattern of displacing methane gas with water in the coal seam water injection process for the prevention and control of gas disasters. …”
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Climate Change and Its Impacts on the Planting Regionalization of Potato in Gansu Province, China by Yulan Lu, Junying Han, Guang Li, Zhengang Yan, Lixia Dong, Zhigang Nie, Qiang Liu

“…The average temperature in July showed a decreasing spatial pattern from northeast to southwest, while its tendency rate showed a decreasing trend from west to east and from north to south. …”
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