Immune-related adverse events of neoadjuvant immunotherapy in patients with perioperative cancer: a machine-learning-driven, decade-long informatics investigation by Yuan Meng, Rong Hu, Song-Bin Guo, Deng-Yao Liu, Zhen-Zhong Zhou, Hai-Long Li, Wei-Juan Huang, Xiao-Peng Tian

“…During the past decade, the amount of research in the field of NAI safety has displayed a positive trend (annual growth rate: 30.2%), and it has achieved good global collaboration (international coauthorship: 17.43%). …”
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Lipidomic analyses reveal the dysregulation of oxidized fatty acids (OxFAs) and acyl-carnitines (CARs) in major depressive disorder: a case-control study by Lei He, Na Duan, Chong Wang, Ru Shan, Jing Li, Lin Wang, Qiuli Liu, Junwei Tao, Li Liu, Xiaoliang Ma, Bing Cao

“…Results Based on the filtering criteria of false discovery rate (FDR) -adjusted P < 0.05, variable importance in projection (VIP) > 1.5, and fold change (FC) > 2.0 or < 0.5, a total of 40 lipids were identified as significantly different. …”
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The cost effectiveness of a multidomain intervention on physical, cognitive, vascular, dietary and psychosocial outcomes among community dwelling older adults with cognitive frailt... by Pavapriya Ponvel, Suzana Shahar, Devinder Kaur Ajit Singh, Arimi Fitri Mat Ludin, Ponnusamy Subramaniam, Norhayati Ibrahim, Hasnah Haron, Aniza Ismail, Chin Ai-Vyrn, Mazlyfarina Mohamad, Hidayah Fadzil, Norhayati Mustafa Khalid, A’isyah Mohammad Safien, Jamilah Mohammad Hanipah, Azyana Ibrahim, Jenni Lehtisalo, Miia Kivipelto, Francesca Mangialasche

“…Despite a 50% dropout rate, adherence among remaining participants was over 50% for all intervention components (range 53%-91%). …”
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Effects of different exercise modalities on blood pressure and endothelial function in prehypertension individuals: a systematic review and network meta-analysis by Yingtian Yang, Qianyu Lv, Xinzheng Hou, Yanfei Lv, Xirui Zhang, Qian Wu, Xuejiao Ye, Chenyan Yang, Mingyu Huang, Shihan Wang

“…The surface underneath the cumulative ranking curve data was utilized to rate interventions. Confidence was evaluated using the CINeMA framework.ResultsA total of 18 articles with 2,592 individuals were included in the NMA. …”
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Identification of a multiple DAMP scavenger mimicking the DAMP-binding site of TLR4 to ameliorate lethal sepsis by Takuya Murao, Gaifeng Ma, Atsushi Murao, Alok Jha, Jingsong Li, Yongchan Lee, Mian Zhou, Ping Wang, Ping Wang, Monowar Aziz, Monowar Aziz

“…Endogenous molecules released from stressed or damaged cells, known as damage-associated molecular patterns (DAMPs), exacerbate inflammation, organ injury, and mortality in sepsis. …”
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Climate change-induced shifts in landslide susceptibility in São Sebastião (southeastern Brazil) by Enner Alcântara, Cheila Flávia Baião, Yasmim Carvalho Guimarães, José Antonio Marengo, José Roberto Mantovani

“…Frequency Ratio (FR) analysis revealed varying levels of landslide susceptibility across scenarios, with RCP2.6 showing lower probabilities for moderate landslides (FR: 0.007946) compared to higher ratings for RCP4.5, RCP6.0, and RCP8.5 (FR: 1.663156 for high landslides). …”
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Prospective Study of the Association Between Frailty and Health Care Utilization in Patients With Advanced CKD by Alice L. Kennard, Alice M. Richardson, Suzanne Rainsford, Kelly L. Hamilton, Nicholas J. Glasgow, Kate L. Pumpa, Angela M. Douglas, Girish S. Talaulikar

“…Negative binomial regression was used to model health care utilization patterns. Frailty progression over study follow-up was described using Cox proportional hazards modelling. …”
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Watching live performances enhances subjective and physiological emotional responses compared to viewing the same performance on screen by Damien Gabriel, Julie Devos, Sandrine Chapuis, Alexandre Comte, Pierre-Edouard Billot

“…Heart rate increased with musical intensity in both conditions, while EEG data showed reduced arousal levels during the live performance, possibly reflecting deeper cognitive absorption. …”
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Concrete Dam Deformation Prediction Model Based on Attention Mechanism and Deep Learning by ZHANG Hongrui, CAO Xin, JIANG Chao, ZU Anjun, XU Mingxiang

“…A comprehensive comparative analysis was conducted against multiple linear regression (MLR), ELM, gated recurrent unit (GRU), and convolutional-long short-term memory (C-LSTM) methods. …”
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Real-world effectiveness of post-trastuzumab emtansine treatment for human epidermal growth factor receptor 2-positive metastatic breast cancer: a multicenter, matched cohort analy... by C. Courtinard, V. Barbet, R. Schiappa, F. Pilleul, S. Michiels, S. Dabakuyo, S. Gourgou, A. Jaffre, B. Asselain, L. Bosquet, K. Dunton, M. Rosenlund, Z. Liang, J. Cathcart, S. Delaloge

“…Patients and methods: Patients from the French Epidemiology Strategy and Medical Economics (ESME) mBC database who initiated treatment for HER2+ mBC between 1 January 2008 and 31 December 2016, and received one or more treatment lines following T-DM1 were propensity score matched 1 : 1 to patients from DESTINY-Breast01 to create an ESME DB-01 matched cohort. Treatment patterns, real-world best overall response, real-world objective response rate (rwORR), real-world disease control rate (rwDCR), real-world progression-free survival (rwPFS), and overall survival (OS) were estimated, including by prior pertuzumab exposure and de novo/relapsed mBC status. …”
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Stomata as the Main Pathway for the Penetration of Atmospheric Particulate Matter Pb into Wheat Leaves by Ke Zhang, Yujing Liang, Chuang Ma, Haopeng Guo, Fuyong Liu, Aihua Gao, Nan Liu, Hongzhong Zhang

“…In this study, spraying Pb(NO₃)₂ (Treatment T1) and spraying PbS (Treatment T2) were used as soluble and insoluble Pb, respectively, to evaluate the primary pathways of APM-Pb absorption by wheat leaves, as well as the translocation and accumulation patterns of Pb within the wheat plant. The results showed that both soluble and insoluble Pb can be absorbed by wheat leaves. …”
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Mechanism Analysis and Establishment of a Prediction Model for the Total Pressure Loss in the Multi-Branch Pipeline System of the Pneumatic Seeder by Wei Qin, Cheng Qian, Yuwu Li, Daoqing Yan, Zhuorong Fan, Minghua Zhang, Ying Zang, Zaiman Wang

“…This study aims to clarify the nonlinear pressure loss patterns of the pneumatic system in a pneumatic seeder under varying pipeline structures and airflow parameters, and to develop a rapid prediction equation for the main pipe’s pressure loss. …”
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Estimation and Forecasting of Nigeria&#x2019;s Residential, Commercial, and Industrial Electricity Demands by Prosper O. Ugbehe, Ogheneruona E. Diemuodeke, Daniel O. Aikhuele, Kenneth E. Okedu, Gauri Kalnoor

“…Suppressed electric energy demand arises from inadequate energy access accounting for unmet electricity needs such as electricity capacity utilization, access rate, outages, and transmission and distribution (T&#x0026;D) losses. …”
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Anemia in Patients with Axial Spondyloarthritis is Not Associated with an Increase of Arterial Stiffness and Intima-Media Thickness (Results of a Single-Center Cross-Sectional Stud... by K. N. Safarova, V. I. Makhina, K. D. Dorogoykina, A. P. Rebrov

“…We consider that potential protective effect of anemia, due to well-known pathophysiological patterns — a decrease in blood viscosity and the induction of nitric oxide synthesis, plays an important role. …”
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Prevalence, Risk Factors, and Antibiogram of Nontyphoidal Salmonella from Beef in Ambo and Holeta Towns, Oromia Region, Ethiopia by Endrias Zewdu Gebremedhin, Gezahegn Tafesse Soboka, Bizunesh Mideksa Borana, Lencho Megersa Marami, Edilu Jorga Sarba, Nega Desalegn Tadese, Hirut Abebe Ambecha

“…The Salmonella detection rate in abattoirs, butchers, and restaurants was 4.2% (5/118), 8.5% (10/118), and 4.2% (5/118), respectively. …”
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Scalable Clustering of Complex ECG Health Data: Big Data Clustering Analysis with UMAP and HDBSCAN by Vladislav Kaverinskiy, Illya Chaikovsky, Anton Mnevets, Tatiana Ryzhenko, Mykhailo Bocharov, Kyrylo Malakhov

“…The focus is on identifying patterns that correlate with cardiac health risks, potentially aiding in early detection and personalized care. …”
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Evaluation of lung cancer early detection offered by the German Social Accident Insurance for formerly asbestos-exposed employees using low-dose computed tomography – setting and s... by Felix Greiner, Jan Heidrich, Helena Keller, Dirk Taeger, Thorsten Wiethege, Volker Harth

“…Primary endpoints are participation patterns, the rate of findings requiring further diagnostic investigation, the detection of lung cancer including tumour stage and characteristics, and the notification and recognition of asbestos-related occupational diseases. …”
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Clinical management and analysis of immune-related adverse events in neoadjuvant immunotherapy for locally advanced rectal cancer by AN Yang, WANG Chentong, QIU Xiaoyuan, ZHOU Jiaolin, LIN Guole

“…Descriptive statistics were used to summarize irAEs patterns and management approaches. Results: A total of 41 irAE episodes occurred among the 30 patients. …”
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Global, regional, and national burden of male breast cancer and predictions in the next 30 years: a systematic analysis of the global burden of disease study 2021 by YaRong Wang, Liang Wang, Bei Yu, Shuang Wen, Xiaoxi Mou, Lin Yang

“…Given these trends, male breast cancer remains a significant global health concern, and emerging disease patterns must inform new control policies.…”
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Air leakage characteristics and comprehensive prevention of goaf side retained roadway of fully mechanized mining faces in Qincheng coal mine by Xin Luo, Liang Chen, Bing Wu, Mengchen Sun, Tao Yang, Hongyang Yu

“…Abstract Mastering the deformation and air leakage patterns of gob-side retained roadway in fully mechanized mining faces, as well as the distribution characteristics of the gas flow field, is of great significance for the comprehensive prevention and control of gas in the goaf. …”
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