Dramatic resurgence of malaria after 7 years of intensive vector control interventions in Eastern Uganda. by Moses R Kamya, Joaniter I Nankabirwa, Emmanuel Arinaitwe, John Rek, Maato Zedi, Catherine Maiteki-Sebuguzi, Jimmy Opigo, Sarah G Staedke, Ambrose Oruni, Martin J Donnelly, Bryan Greenhouse, Jessica Briggs, Paul J Krezanoski, Teun Bousema, Philip J Rosenthal, Peter Olwoch, Prasanna Jagannathan, Isabel Rodriguez-Barraquer, Grant Dorsey

“…In Busia, An. gambiae s.s. remained the primary vector throughout the observation period. Sporozoite rates were approximately 50% higher among An. funestus compared to the other common malaria vectors. …”
Get full text

Treatment of total hip arthroplasty between two surgical access routes associated chronic pain, function and biomechanical parameters in older after osteoporotic femur fracture: co... by Marco Antônio Leite Pereira Pinto, Giovanna Truyts Biscardi Pinto, Mariana Afonso Ribeiro Sarquis Ude, Claudia Aparecida de Morais, Ana Paula Ribeiro

“…Conclusion Total hip arthroplasty via the posterolateral approach proved to be more successful when associated with reducing chronic pain, improving functional parameters and hip joint mobility, as well as facilitating a more efficient gait pattern with lower rates of plantar overload and enhanced body balance in older adults undergoing total hip arthroplasty after osteoporotic femur fracture. …”
Get full text

Epstein Barr virus antibody and cancer risk in two prospective cohorts in Southern China by Ming-Fang Ji, Yong-Qiao He, Min-Zhong Tang, Wen-Qiong Xue, Xia Yu, Hua Diao, Da-Wei Yang, Zhi-Ming Mai, Io Hong Cheong, Zhi-Yang Zhao, Biao-Hua Wu, Fu-Gui Li, Ji-Yun Zhan, Chang-Ling Huang, Hao-Lin Ma, Jun Li, Yan-Cheng Li, Tong-Min Wang, Ying Liao, Xue-Yin Chen, Zhi-Heng Liang, Shi-Feng Lian, Yun Du, Xue-Jun Liang, Zisis Kozlakidis, Jun Ma, Wei-Hua Jia

“…The associations showed an increased dose-response pattern, and keep persistent even up to ten years prior to diagnosis. …”
Get full text

Distribution and extended triage of high-risk human papillomavirus genotyping based on vaginal self-sampling by Ling Li, Yun Zhao, Rong Liu, Chen Yao, Zhijun Zhang, Yingying Hu, Ruifang Wu, Ruifang An, Hui Du, Xinfeng Qu, Lihui Wei, Bei Lin, Mingzhu Li, Chao Zhao, Jingran Li, Zhixin Lin, Jihong Deng, Songling Zhang

“…Different HPV subtypes have different detection rates for CIN2+, and combining HPV16/18/33 significantly improved the sensitivity for detecting CIN2+.…”
Get full text

The human RNASET2 alarmin-like molecule differentially affects prostate cancer cells behavior in both cell autonomous and non-cell autonomous manners by Rossella Roncoroni, Denisa Baci, Martina Cucchiara, Annarosaria de Vito, Matteo Gallazzi, Maria Teresa Palano, Francesca Olmeo, Cristian Rubuano, Alessandra Giannatiempo, Laura Monti, Raffaella Bombelli, Daniele Mercatelli, Giovanna Finzi, Francesca Franzi, Stefano La Rosa, Douglas M. Noonan, Barbara Bassani, Lorenzo Mortara, Antonino Bruno, Francesco Acquati

“…Here, we investigated the effects of the human RNASET2 alarmin in two different human PCa cell lines focusing on cell proliferation, colony formation, adhesion, migration rates, and release of soluble immune-modulatory factors. …”
Get full text

Modulatory role of radioprotective 105 in mitigating oxidative stress and ferroptosis via the HO-1/SLC7A11/GPX4 axis in sepsis-mediated renal injury by Hong Duo, Yanwei Yang, Jun Luo, Yumeng Cao, Qian Liu, Jiarui Zhang, Siqi Du, Jian You, Guqing Zhang, Qifa Ye, Huaqin Pan

“…Abstract Sepsis-associated acute kidney injury (SA-AKI) is a critical condition characterized by high morbidity and mortality rates, particularly in intensive care settings. This study focuses on RP105, a pattern recognition receptor, exploring its role in moderating the mechanisms of oxidative stress and ferroptosis during SA-AKI, offering insights into its potential as a therapeutic target. …”
Get full text

Red cell distribution width-to-platelet ratio (RPR) as a predictor of prolonged stay at hospital for COVID-19 inpatients by Martha Fors, Santiago J. Ballaz

“…One exemption was the red cell distribution width-to-platelet ratio (RPR) index, which can increase the probability of a longer hospital stay by up to ten times (HR(IC95%) = 0.092(0.03-0.29); p < 0.001).Conclusion The most effective biomarker to identify COVID-19 patients at high risk for extended hospital stay was RPR.Highlights IntroductionDetermining hospital Length of Stay (LoS) is vital for resource management, especially for future COVID-19 outbreaks.Previous studies have primarily focused on sociodemographic and clinical attributes, along with resource availability, but have not accounted for other factors like routine laboratory tests, which can significantly impact LoS predictions.This study examines novel hematology scores as predictors of LoS, emphasizing their importance in resource-limited settings like Ecuador.MethodsThis retrospective cohort study analyzed 2,930 COVID-19 patients admitted to Hospital IESS Quito Sur in Ecuador focusing on confirmed cases with complete blood count (CBC) values to assess LoS.The study explored various hematological ratios, such as the neutrophil-to-lymphocyte ratio (NLR) and red cell distribution width-to-lymphocyte ratio (RLR), as potential predictors of LoS and in-hospital outcomes for COVID-19 patients, using a combination of univariate and multivariable Cox proportional hazards regression models.Kaplan-Meier survival estimates and log-rank tests were used to analyze survival and discharge probabilities over time, highlighting sex-dependent effects and the significant association between selected hematological indices and patient outcomes.ResultsThe mean LoS for survivors was significantly shorter compared to those who died (p < 0.001), indicating that longer hospitalization was associated with higher mortality risk.Women had a shorter average LoS (with lower mortality risk (p < 0.001), suggesting an asymmetrical hospitalization pattern based on sex.While most hematological markers had minimal clinical relevance for LoS, the red cell distribution width-to-platelet ratio (RPR) stood out, increasing the likelihood of a longer hospital stay by up to tenfold, making it a critical factor in predicting prolonged hospitalization.DiscussionMen had longer hospital stays and higher mortality rates than women, likely due to differing inflammatory responses, though hyperinflammation markers like NLR, PLR, and Leu-CPR had minimal clinical impact.RPR had the strongest link to longer hospital stays, indicating a higher risk of extended hospitalization in severe COVID-19 cases.Elevated RPR is tied to oxidative stress and coagulation issues, suggesting early identification could help reduce prolonged stays and complications.ConclusionResearch generally points to clinical complications from COVID-19 as the main factor behind prolonged hospitalizations, underlining the importance of early identification and management of these issues.…”
Get full text

Somatization symptoms and burnout: a correlational study among emergency nurses by Ningxiang Li, Ningxiang Li, Ningxiang Li, Nan Xie, Nan Xie, Nan Xie, Xiaoli Chen, Xiaoli Chen, Xiaoli Chen, Hao Zhang, Hao Zhang, Hao Zhang, Luying Zhong, Luying Zhong, Luying Zhong, Dongmei Diao, Dongmei Diao, Dongmei Diao, Ling Zhu, Ling Zhu, Ling Zhu, Yue Zhou, Yue Zhou, Yue Zhou

“…Data collection occurred between December 26, 2023, and January 18, 2024, using the Chinese versions of the Maslach burnout inventory–general survey (MBI-GS) and the somatic symptom disorder self-rating scale (SSD-CN). Statistical analyses were performed using SPSS version 25.0.ResultsThe mean SSD score was 39.58 ± 13.61, with 53.4% of participants exhibiting moderate to severe somatization symptoms. …”
Get full text

Analysis of the Contextual Factors Influencing the Expansion of Construction Violations with an Emphasis on the Role and Position of Key Urban Stakeholders (Case Study: Isfahan Met... by Ahmad Shahivandi, Afsaneh Talebi Varnosfaderani

“…Additionally, natural population growth—encompassing births, improvements in healthcare, and reduced mortality rates—had a factor loading of 0.74, further impacting the urbanization process. …”
Get full text

Differences in the inflammatory response and outcome among hospitalized patients during different waves of the COVID-19 pandemic by Violeta Briciu, Violeta Briciu, Daniel-Corneliu Leucuta, Monica Muntean, Monica Muntean, Amanda Radulescu, Amanda Radulescu, Cristina Cismaru, Cristina Cismaru, Adriana Topan, Adriana Topan, Lucia Herbel, Melinda Horvat, Melinda Horvat, Mirela Flonta, Mihai Calin, Roxana Dobrota, Mihaela Lupse, Mihaela Lupse

“…Systemic inflammatory indexes like neutrophil-to-lymphocyte ratio (NLR), derived neutrophil-to-lymphocyte ratio (dNLR), lymphocyte-to-monocyte ratio (LMR), platelet-to-lymphocyte ratio (PLR), neutrophil-to-platelet ratio (NPR), Systemic Immune-Inflammation Index (SII), and systemic inflammation response index (SIRI) were calculated.ResultsThe Delta wave, characterized by the longest hospitalizations and the highest rates of severe cases and mortality, showed significant elevations in inflammatory biomarkers. …”
Get full text

Effect of Different Treatments on the Structure Sequence and Digestive Characteristics of Oyster Hypoglycemic Peptides by Hua WANG, Xiaojie SU, Zhongqin CHEN, Wenhong CAO, Jialong GAO, Guoping ZHU, Haisheng LIN

“…Moreover, the retention rates of OHPs' inhibitory activity against α-amylase and α-glucosidase were enhanced by alcohol precipitation and activated carbon adsorption treatments. …”
Get full text

Assessment of Preserved Ratio Impaired Spirometry (PRISm) Based on Different Definitions in the Early COPD Cohort by Dai C, Tang G, Yang H, Wu F, Deng Z, Zheng Y, Zhao N, Lu L, Wan Q, Wang Z, Peng J, Wu X, Zhou K, Cai G, Xiao S, Wen X, Yang C, Chen S, Yu S, Sun R, Zhou Y, Ran P

“…Furthermore, the prevalence of PRISm varied from 2.0% to 12.5% depending on the definitions and predicted equations, with the Chinese equation, LLN definition in Chinese equation and fixed definition in GLI equation yielding higher prevalence rates.Conclusion: Our findings highlight concerns about the comparability of studies and the interchangeability of various definitions and reference equations for PRISm.Keywords: PRISm, definitions, clinical features, prevalence, reference equations…”
Get full text

Tratamento de sequelas de queimadura de face com laser de CO2 fracionado em pacientes com fototipos III a VI Treatment of facial burn sequelae using fractional CO2 lasers in patien... by Alessandra Grassi Salles, Adelina Fátima do Nascimento Remigio, Valéria Berton Liguori Zacchi, Marcus Castro Ferreira

“…CONCLUSIONS: The treatment with CO2F laser with mild parameters was well tolerated and resulted in high satisfaction rates for patients with facial burn sequelae as well as improved skin texture, distensibility, and surface irregularities. …”
Get full text

Investigation of Population Changes and Determination of the Bean Pod Borer Helicoverpa armigera (Lepidoptera:Noctuidae) Peak in Bean Phaseolus vulgaris Linnaeus Fields by Pheromon... by Sedighe Ashtari

“…The investigation of the distribution and damage level of bean pod borer in important bean-growing areas of Markazi province over two years in five bean-growing regions (Arak, Khomain, Shazand, Milajerd, and Khondab) showed that Khomain and Khondab had the highest and lowest infestation rates, respectively. Red pods showed more sensitivity to this pest compared to green and white pods. …”
Get full text

Renal prognostic value of serum monoclonal immunoglobulin in cryoglobulinemic glomerulonephritis by Lei Ma, Yuanyuan Xia, Yun Fan, Dan Zhou, Xinchen Yao, Yongzhong Zhong, Fan Yang, Feng Xu, Shaoshan Liang, Yujie Wang, Xiaodong Zhu, Dacheng Chen, Rong Tan, Zhengyun Zhu, Dandan Liang, Caihong Zeng

“…The MIg group had significantly lower eGFR levels, higher cryoglobulin levels, and higher rates of abnormal serum-free light chain ratios than the MIg/HBV/HCV negative group. …”
Get full text

Classification of finger movements through optimal EEG channel and feature selection by Murside Degirmenci, Yilmaz Kemal Yuce, Matjaž Perc, Matjaž Perc, Matjaž Perc, Matjaž Perc, Matjaž Perc, Yalcin Isler

“…This study design may result in an increasing number of false positives and a significant decrease in the prediction rates and classification performance. Moreover, recent studies have focused on improving prediction performance using complex feature extraction and machine learning algorithms while ignoring comprehensive EEG channels and feature investigation in the prediction of finger movements from EEGs. …”
Get full text

Calculation Model of Multi-roll Straightening Process Based on Bilinear Hardening and Power Hardening by ZHU Xiaoyu, CHENG Zixing, WANG Xiaogang, HAN Peisheng

“…To evaluate the applicability of different material models, five straightening schemes were designed, corresponding to plasticity rates of 33.4%, 50.0%, 66.7%, 75.0%, and 80.0%. The influence of various hardening coefficients on curvature and plasticity during straightening was investigated. …”
Get full text

Risk of developing drug abuse in administration of a new hexaazaisowurtzitane derivative-based analgesic (experimental study) by S. G. Krylova, T. N. Pove’teva, K. A. Lopatina, Yu. V. Nesterova, E. P. Zueva, O. G. Afanas’eva, P. V. Kulpin, E. A. Kiseleva, N. I. Suslov, D. A. Kulagina, S. V. Sysolyatin, V. V. Zhdanov

“…Previous in vivo and in silico studies (docking, molecular modeling, molecular dynamics simulation) on the multi-target mechanism of thiowurtzine explain the absence of its morphine-like effect by the fact that the major targets of the analgesic are TRPA1 receptors and voltage-gated Ca 2+ channels. With a high degree of probability, the conclusions made herein predict no drug abuse development when thiowurtzine is used in the clinical setting. …”
Get full text

Analysis of complex chromosomal structural variants through optical genome mapping integrated with karyotyping by Xiaoxi Zhu, Huiling Zheng, Xue Wan, Hang Duan, Ying Qi, Weijia Tang, Fan Yang, Fan Yang, Limei Yu, Limei Yu

“…This advancement substantially enhances the diagnostic rates of genetic etiology in patients experiencing RSA. …”
Get full text

Dependence of Indicators of Daily Blood Pressure Monitoring on Activity of Pathological Process in Patients with Systemic Lupus Erythematosus by Abrahamovych O., Abrahamovych U., Kushyna A., Guta S., Synenkyi O.

“…According to the first goal was rated the BP in the SLE patients during the period of 24 hours, for which: a) were examined the average daily, maximum and minimum levels of systolic blood pressure (SBP), diastolic blood pressure (DBP), the average blood pressure; b) was analysed the daily index (DI) of SBP, DBP and the average blood pressure; c) was examined the time index (TI) of SBP, DBP and the average blood pressure. …”
Get full text