Laboratory based antimicrobial resistance surveillance for Pseudomonas aeruginosa blood isolates from South Africa by Ashika Singh-Moodley, Adriano Duse, Preneshni Naicker, Ranmini Kularatne, Trusha Nana, Ruth Lekalakala, Nontombi Mbelle, Halima Dawood, Khine Swe Swe Han, Praksha Ramjathan, Prathna Bhola, Andrew Whitelaw, Olga Perovic

“…Pseudomonas aeruginosa is an opportunistic healthcare-associated pathogen with high rates of morbidity and mortality and an extensive range of resistance mechanisms. …”
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Hemotropic pathogens in aborted fetuses of domestic ruminants: transplacental transmission and implications for reproductive loss by Daria Jurković Žilić, Šimun Naletilić, Željko Mihaljević, Ema Gagović, Silvio Špičić, Irena Reil, Sanja Duvnjak, Maja Zdelar Tuk, Adnan Hodžić, Relja Beck

“…The highest infection rates were observed in cattle (17.27%) and sheep (15.85%), while goats showed significantly lower prevalence (5.3%). …”
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Effects of Physiological Loading from Patient-Derived Activities of Daily Living on the Wear of Metal-on-Polymer Total Hip Replacements by Benjamin A. Clegg, Samuel Perry, Enrico De Pieri, Anthony C. Redmond, Stephen J. Ferguson, David E. Lunn, Richard M. Hall, Michael G. Bryant, Nazanin Emami, Andrew R. Beadling

“…The results indicate that jogging significantly increased wear rates compared to the ISO walking gait waveform, with wear increasing from 15.24 ± 0.55 to 28.68 ± 0.87 mm³/Mc. …”
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Regulation of high-temperature microstructure evolution and recrystallization by pre-strain accumulation in Al–Zn–Mg–Cu alloys by Dejin Wei, Guoqun Zhao, Luyi Han, Kunpeng Deng

“…The deformation characteristics were examined under specific conditions: deformation temperature of 440 °C, strain rates of 0.001 s−1 and 0.1 s−1, and a deformation degree of 60 %. …”
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Socioeconomic disparities in incidence, treatment, and survival of intrahepatic cholangiocarcinoma: insights from a nationwide cohort study in SwedenResearch in context by Juan Vaz, Hannes Hagström, Per Sandström, Malin Sternby Eilard, Magnus Rizell, Ulf Strömberg

“…Household income– categorised as low (lowest national quartile), medium, or high (highest quartile)–was used as the SES indicator. Incidence rates (IRs), treatment patterns, and survival were analysed across income strata. …”
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Impact of Age and Menopausal Status on T-DM1 (Ado-Trastuzumab Emtansine) Treatment Outcomes in HER2-Positive Breast Cancer by Heves Surmeli, Deniz Isik, Oguzcan Kinikoglu, Yunus Emre Altintas, Ugur Ozkerim, Sıla Oksuz, Tugba Basoglu, Hatice Odabas, Nedim Turan

“…<b>Results</b>: The postmenopausal patients showed higher rates of lung metastasis (42.2% vs. 20.8%) and mortality (60.0% vs. 39.6%) than premenopausal patients. …”
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The Global Burden of Multidrug-Resistant Bacteria by Andrea Marino, Antonino Maniaci, Mario Lentini, Salvatore Ronsivalle, Giuseppe Nunnari, Salvatore Cocuzza, Federica Maria Parisi, Bruno Cacopardo, Salvatore Lavalle, Luigi La Via

“…We evaluate the effectiveness of various antimicrobial stewardship programs, documenting success rates and implementation challenges across different healthcare settings. …”
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Machine learning-based source apportionment and source-oriented probabilistic ecological risk assessment of heavy metals in urban green spaces by Jun Li, Jia-Yi Lu, Xin-Ying Tuo, Chao Wang, Jun-Zhuo Liu, Zhan-Dong Gao, Cun-Hao Yu, Fei Zang

“…Results showed that the average concentrations of Cd (0.38 mg kg−1), Cu (35.51 mg kg−1), Hg (0.07 mg kg−1), Pb (34.59 mg kg−1), and Zn (130.58 mg kg−1) exceeded local soil background values, except for As (8.56 mg kg−1), Cr (62.77 mg kg−1), and Ni (27.68 mg kg−1). Notably, exceedance rates for Cd, Hg, Pb, and Zn were 90.91 %, 94.95 %, 80.81 %, and 87.88 %, respectively. …”
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The role of JPT1 in hepatocellular carcinoma: tumor progression, microtubule dynamics regulation, and potential mechanisms within the immune microenvironment by Yipin Lu, Peng Xu, Sha Li, Jie Yao

“…A pan-cancer analysis was performed to evaluate JPT1 expression patterns and prognostic value across multiple cancer types. …”
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Prediction efficiency and incremental processing strategy during spoken language comprehension in autistic children: an eye-tracking study by Zihui Hua, Tianbi Li, Ruoxi Shi, Ran Wei, Li Yi

“…However, autistic children exhibited reduced prediction efficiency compared to neurotypical peers, evidenced by significantly lower proportions of and slower growth rates in fixations to target objects relative to unrelated distractors, and delayed onset of predictive looking. …”
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Inflammatory markers mediate the association between alternative adiposity indices and mortality in patients with rheumatoid arthritis: data from NHANES 1999–2018 by Feng Luo, Jia-jie Guo, Xue-mei Yuan, Heng Zhou, Qiu-yi Wang, Chang-ming Chen, Xue-ming Yao, Wu-kai Ma

“…Conclusions This study revealed a potential clinical value of a new obesity index, specifically the ABSI, in predicting the survival rates among individuals with RA. Inflammatory markers appear to play a partial mediating role in this relationship. …”
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Spatial distribution and predictors of early childbearing among Ethiopian women: evidence from the 2016 Ethiopian Demographic and Health Survey by Amare Teshome Tefera, Fanuel Gashaw, Martha Solomon, Nebiyu Bekele, Shegaye Shumet, Tigist Mulugeta, Araya Mesfin Nigatu, Solomon Gedlu Nigatu

“…Abstract Background Age at first birth is a crucial factor in understanding fertility patterns within a population. Ethiopia reports high rates of maternal and child mortality alongside elevated fertility levels. …”
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Comparison of neoadjuvant chemoimmunotherapy with planned surgery and concurrent chemoradiation followed by immunotherapy for potentially resectable stage III non-small-cell lung c... by Yana Qi, Xiaoyang Zhai, Qinhao Xu, Yuqin Jin, Yingfan Guo, Miaoqing Zhao, Hui Zhu, Hongbo Guo

“…Median overall survival (OS) was NR in either group, with 3-year OS rates of 87.5% in the neoCT/IO group and 75.0% in the cCRT + IO group (p = 0.22). …”
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Epidemiological and clinical analysis, and outcomes of tuberculosis co-infection among people living with HIV in Türkiye (2014-2024) ClinSurv HIV cohort: A large case series. by Ali Mert, Okan Derin, Esra Zerdali, Abdurrahman Kaya, Özlem Gül, Deniz Borcak, Ahmet Furkan Kurt, Meliha Meriç Koç, Bircan Kayaaslan, Ayşe Batırel, Alper Gündüz, İnci Yılmaz Nakir, Gülşen Yörük, Dilek Yıldız Sevgi, Hayat Kumbasar Karaosmanoğlu, Bilgül Mete, Melike Nur Özçelik, Nagehan D Sarı, Yasemin Akkoyunlu, Fehmi Tabak

“…The positivity rates of Ehrlich-Ziehl-Neelsen staining (EZN), polymerase chain reaction (PCR), and TB cultures in clinical samples were found to be 47.5%, 72.5%, and 53%, respectively. …”
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Conversational AI agent for precision oncology: AI-HOPE-WNT integrates clinical and genomic data to investigate WNT pathway dysregulation in colorectal cancer by Ei-Wen Yang, Brigette Waldrup, Enrique Velazquez-Villarreal, Enrique Velazquez-Villarreal

“…Exploratory queries further assessed treatment response, co-mutation patterns, and population-specific trends.ResultsIn recapitulation analyses, AI-HOPE-WNT reproduced key trends from prior work, including improved survival in WNT-altered EOCRC and higher RNF43 mutation rates in Hispanic/Latino (H/L) populations compared to non-Hispanic White (NHW) people. …”
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Estimating the burden of disease attributable to non-assisted suicide in Switzerland from 2009 to 2021: a secondary data analysis by Annora Mack, Sarah Rajkumar, Jacob Kofler, Kaspar Wyss

“…The stark sex disparity in suicide rates further underscores the need for sex-sensitive approaches. …”
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Heterogeneity of Candida bloodstream isolates in an academic medical center and affiliated hospitals by Nancy E. Scott, Elizabeth Wash, Christopher Zajac, Serin E. Erayil, Susan E. Kline, Anna Selmecki

“…Phenotypic data, including patterns of antifungal drug resistance, are limited. …”
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Survival outcomes and prognostic impact of adjuvant chemotherapy in stage IB lung adenocarcinoma with cribriform component by Rongyang Li, Yu Zhang, Jianhao Qiu, Mingyang Zang, Zhenguo Sun

“…The results showed that both the 5-year overall survival (OS) rates (63.5% vs. 84.5%, P = 0.013) and 5-year recurrence-free survival (RFS) rates (58.7% vs. 77.7%, P = 0.033) for cribriform-positive patients were lower than those for cribriform-negative patients. …”
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Ornidazole-Induced Liver Injury: The Clinical Characterization of a Rare Adverse Reaction and Its Implications from a Multicenter Study by Ali Rıza Çalışkan, Ilker Turan, Sezgin Vatansever, Jasmin Weninger, Emine Türkmen Şamdancı, Ayşe Nur Akatli, Elvan Işık, Esra Durmazer, Ayşenur Arslan, Nilay Danış, Hüseyin Kaçmaz, Sedat Cicek, Osman Sağlam, Dilara Turan Gökçe, Derya Arı, Sevinç Tuğçe Güvenir, Serkan Yaraş, Cumali Efe, Meral Akdoğan Kayhan, Murat Harputluoğlu, Ali Canbay, Ulus Salih Akarca, Zeki Karasu, Ramazan Idilman, Fulya Günşar

“…Corticosteroids were used in 24.8% of cases (n = 25) and were associated with higher ANA positivity and a 20% (n = 5) relapse rate post-discontinuation. Recovery was achieved in 87.7% of cases (n = 88), while 7.9% of cases (n = 8) required liver transplantation and 4% (n = 4) died. …”
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Type II diabetes in systemic sclerosis patients: insights from an observational, multicenter study of GIRRCS (Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale) by Vasiliki Liakouli, Giulio Forte, Piero Ruscitti, Luca Navarini, Francesca Bellisai, Francesco Caso, Giuliana Guggino, Lidia La Barbera, Chiara Rizzo, Ada Corrado, Paola Triggianese, Alberto Lo Gullo, Giuseppe Mandraffino, Luca Cantarini, Bruno Frediani, Paola Cipriani, Francesco Paolo Cantatore, Maria Sole Chimenti, Elvira Favoino, Federico Perosa, Annamaria Iagnocco, Roberto Giacomelli, Francesco Ciccia

“…SSc patients with T2D were significantly older (P < 0.007) and exhibited: higher prevalence of late-stage capillaroscopic pattern (P < 0.001), severe reduction in forced vital capacity (FVC < 50%; P < 0.000), moderate reduction in total lung capacity (TLC 50–69%; P < 0.011), electrocardiographic signs of right ventricular hypertrophy (P < 0.018), higher prevalence of pulmonary arterial hypertension (PAH) confirmed by right heart catheterization (RHC) (P < 0.037) and higher prevalence scleroderma renal crisis (SRC) (P < 0.001); elevated erythrocyte sedimentation rate (ESR) (P < 0.022), and ANA positivity. …”
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