The global, regional, and national impact of laryngeal cancer from 1990 to 2021, along with forecasts for 2050: a comprehensive analysis for the Global Burden of Disease 2021 resea... by Tingting Duan, Yuxia Zou, Xuan Liu, Yue Du, Ruihu Li, Jingxiang Cai, Jumei Li, Xiaofeng Wang, Xuejun Zhou, Shun Ding

“…The incidence and mortality rates of male patients are much higher than those of female patients, and the gap between men and women gradually narrows after the age of 70. …”
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Prominent Zakat Institutions and Their Role in Advancing the Welfare of the Muslim Community in The Eastern Province of Sri Lanka by Raseethu Mohamed Kasjin

“…Findings: The study highlights varying growth rates in Zakat collection and fluctuations across regions, with some Zakat fund collections experiencing sharp increases. …”
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Simulation of the impacts of high temperature stress on pepper (Capsicum annum L.) yields by Bomi Park, Sojung Kim, Sumin Kim

“…PHR23, having a larger leaf area, accumulated more biomass than fruit yields in the initial month of exposure, thus increasing its yields at higher temperature conditions due to enhanced photosynthesis rates. The crop growth curve and parameters were formulated based on these studies, and the open field simulations were calibrated with measured yields from multiple locations in South Korea from 2020-2024. …”
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The evolution of irreversible cell differentiation under cell death effect. by Yuanxiao Gao, Xueyan Zhao, Caixia Li

“…We show that irreversible differentiation is more likely to occur when cell death rates between cell types are linear. Meanwhile, differences in death rates between cell types affect the emergence conditions of irreversible differentiation, whereas no significant impacts on that from equal cell death rates. …”
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Cancer Burden in Chinese Older Adults: Insights Into Incidence, Mortality, and Global Comparisons Using GLOBOCAN 2022 by Yuanjie Zheng, He Li, Qianru Li, Siyi He, Yi Teng, Mengdi Cao, Nuopei Tan, Jiachen Wang, Tingting Zuo, Tianyi Li, Wanqing Chen

“…The estimated numbers of new cases and deaths, age‐standardized incidence rates (ASIRs), and age‐standardized mortality rates (ASMRs) were analyzed for the top ten cancer types in Chinese older adults, categorized by sex and age groups (60–69, 70–84, and 85+ years). …”
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MIR155HG promotes metastasis and cisplatin resistance of cervical cancer cells by regulating the miR-409-3p and ZEB1 axis by Yanxia Chen, Jing Wang, Youqiang Heng, Yu Guo, Ka Ding, Cailing Ma

“…Overexpression of MIR155HG (MIR155HG-OE) demonstrated higher proliferation and migration levels in HeLa cells, while MIR155HG inhibited the apoptosis rate of HeLa cells. Meanwhile, we found MIR155HG can reduce the effect of cisplatin sensitivity on HeLa cells. …”
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The influence of the molecular weight of hyaluronic acid on the mangiferin release kinetics from the polymer matrix by P. P. Snetkov, R. O. Shaikenov, V. I. Klimshina, Yu. E. Generalova, S. N. Morozkina

“…Mangiferin release kinetic from a polymer matrix based on hyaluronic acid has a release sigmoidal pattern. The release mechanism has a complex nature of the Super Case II transport type, with the exception of a sample with a low content of mangiferin and hyaluronic acid with molecular weight equal to 1.3 MDa, for which an abnormal release pattern is detected (non-Fickian diffusion), due to the hydrophilic nature of hyaluronic acid, the rapid swelling of the polymer matrix, as well as a significant leading in the diffusion of mangiferin compared to the relaxation rate of the polymer. …”
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Distinctive lung cancer incidence trends among men and women attributable to the period effect in Shanghai: An analysis spanning 42 years by Li Xie, Ying Qian, Yishan Liu, Yixuan Li, Sinong Jia, Herbert Yu, Chunfang Wang, Biyun Qian, Pingping Bao

“…Methods Data were obtained from Shanghai Cancer Registry. Age‐standardized rates were calculated and average annual percent changes (AAPCs) were evaluated by Joinpoint regression. …”
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Genetic and clinical characteristics of catecholaminergic polymorphic ventricular tachycardia in a Taiwanese nationwide cohort by Grace Chia-Yen Hsu, Mei-Hwan Wu, Jing-Yuan Chuang, Shuenn-Nan Chiu, Ming-Tai Lin, Ling-Ping Lai, Shih-Fan Sherri Yeh, Sheng-Fu Liu, Ting-Tse Lin, Fu-Tien Chiang, Jyh-Ming Jimmy Juang

“…Among the 29 Taiwanese patients with CPVT-related gene mutations, 55% had RYR2 mutations, a rate similar to other ethnicities. Three out of 12 RYR2 variants were unreported. …”
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Treatment response in relation to subthreshold bipolarity in patients with major depressive disorder receiving antidepressant monotherapy: a post hoc data analysis (KOMDD study) by Park Y, Lee B

“…The Beck Depression Inventory (BDI), Hamilton Depression Rating Scale (HAMD), Hamilton Anxiety Scale, and Beck Scale for Suicide Ideation were applied at baseline, 1 week, 3 weeks, 2 months, 3 months, and 6 months. …”
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Anthropogenic Activities Dominate Vegetation Improvement in Arid Areas of China by Yu Guo, Xinwei Wang, Hongying Cao, Qin Peng, Yunshe Dong, Yunchun Qi, Jian Liu, Ning Lv, Feihu Yin, Xiujin Yuan, Mei Zeng

“…The results indicated that (1) overall vegetation cover was low (averaged peak FVC = 0.191), showing a spatial pattern of higher values in the northwest and lower values in the southeast; high FVC values were primarily observed in mountainous areas and river corridors; (2) the annual peak FVC increased significantly at a rate of 0.0508 yr⁻¹, with 33.72% of the region showing significant improvements and 5.49% degradation; (3) the spatial pattern of FVC was shaped by the distribution of land use types (59.46%), while the temporal dynamics of FVC were driven by land use changes (16.37%) and the land use intensity (37.56%); (4) both the spatial pattern and the temporal dynamics were limited by the environmental conditions. …”
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Impact of post-transplant cyclophosphamide with bendamustine on immune reconstitution in young patients undergoing T-cell replete haploidentical bone marrow transplantation: result... by Forrest L. Baker, Forrest L. Baker, Forrest L. Baker, Jessica Stokes, Megan J. Cracchiolo, Dan Davini, Richard J. Simpson, Richard J. Simpson, Richard J. Simpson, Richard J. Simpson, Emmanuel Katsanis, Emmanuel Katsanis, Emmanuel Katsanis, Emmanuel Katsanis

“…Multi-parameter flow cytometry and TCR β sequencing of genomic DNA was performed on isolated PBMCs on PT days +30, +60, +100, +180, and +365.ResultsOverall, the PT-CY/BEN (n=14) regimen was associated with earlier neutrophil and platelet engraftment, reduced transfusion requirements, and comparable clinical outcomes to PT-CY (n=10), including survival and relapse rates. PT-CY/BEN patients exhibited distinct immune reconstitution patterns, characterized by earlier CD4+ T-cell recovery, impaired CD8+ T-cell engraftment, and reduced NK-cell counts. …”
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Geospatial Analytics of Urban Bus Network Evolution Based on Multi-Source Spatiotemporal Data Fusion: A Case Study of Beijing, China by Xiao Li, Shaohua Wang, Liang Zhou, Yeran Sun, Jiayi Zheng, Chang Liu, Junyuan Zhou, Cheng Su, Dachuan Xu

“…By analyzing spatial coverage rates of transit stations using road network and administrative division data, the study reveals the convenience of bus networks in different regions. …”
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RNAi-mediated suppression of toll-like receptor NlToll1 enhances Nilaparvata lugens susceptibility to entomopathogenic fungal infection by Zhu-Long Shao, Chen-Ping Lan, Xiao-Ping Yu, Zheng-Liang Wang

“…Toll-like receptors (TLRs) are a family of crucial pattern recognition proteins that are responsible for the immunologic recognition of invading pathogen in insects. …”
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The association between four dietary indices and mortality risk in cardiovascular disease patients by Mengshan Pan, Tongle Yin, Ying Yang, Feiyun Zhu, Jiamin Xu, Rucheng Chen, Weijun Zheng

“…Abstract Background The Planetary Healthy Diet Index-United States, the Healthy Diet Index, the Mediterranean Diet, and the Dietary Inflammation Index were linked to mortality rates in cardiovascular patients. This study investigated the relationship between these dietary patterns and all-cause mortality risk in U.S. cardiovascular patients from 2005 to 2006 to 2017–2018. …”
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Statistics and behavior of clinically significant extra-pulmonary vein atrial fibrillation sources: machine-learning-enhanced electrographic flow mapping in persistent atrial fibri... by Peter Ruppersberg, Steven Castellano, Philip Haeusser, Kostiantyn Ahapov, Melissa H. Kong, Stefan G. Spitzer, Stefan G. Spitzer, Georg Nölker, Andreas Rillig, Tamas Szili-Torok

“…Our machine learning approach established an activity threshold, above which divergent wavefront patterns—termed “significant sources”—predicted AF recurrence. …”
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Integrative single‐cell transcriptomic analysis deciphers heterogeneous characteristics of gastrointestinal tract cancer by Chuwen Sun, Tong Li, Xin Jin, Zhihui Xiu, Hang Su, Huanming Yang, Ming Liu, Kui Wu

“…Abstract Background Gastrointestinal tract cancer (GIC), including oesophageal cancer (EC), gastric cancer (GC) and colorectal cancer (CRC), is characterised with high global incidence and mortality rates, with similar tumourigenic processes. However, the common and heterogeneous molecular features among GIC at single‐cell level remain poorly characterised. …”
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Pitfalls in the diagnosis of apparent homozygous mutations: two cases of IL10RA deficiency inflammatory bowel disease and a literature review by Xiu Shi, Ziqing Ye, Lai Qian, Wenhui Hu, Ye Yang, Chunmeng He, Zhiheng Huang, Bingbing Wu, Ying Huang

“…Abstract Background In East Asia, IL10RA is the predominant pathogenic gene in patients with very early-onset inflammatory bowel disease (VEO-IBD), frequently characterised by refractory diarrhoea and severe perianal disease, resulting in elevated death rates. IL10RA-deficient IBD, an autosomal recessive genetic disorder, has been documented to be inherited through the conventional compound heterozygous or homozygous mutation patterns from both parents. …”
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Multimorbidity frailty index and clinical outcomes among 42,989 older heart failure patients directly discharged from emergency departments: A nationwide retrospective cohort study by Wan-Ju Liao, Hsi-Yu Lai, Liang-Yi Lin, Cheng-Hsueh Wu, Fei-Yuan Hsiao, Liang-Kung Chen

“…Readmission rates showed similar patterns. The severely frail group had higher risks of mortality (aHR 1.44, 95 % CI 1.33–1.55), all-cause readmissions (sHR 1.69, 95 % CI 1.62–1.76), and HF-related readmissions (sHR 1.59, 95 % CI 1.48–1.71). …”
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Farm households’ livelihood adaptive capacity under multiple pressures of small watershed management by Yaru Sun, Yilin Gan, Jing Luo, Tingting Han, Hafo Wang, Ruirui Yang, Lingling Tian

“…However, the FHLAC remains predominantly low to moderate in the small watershed. The contribution rates of livelihood pressure, livelihood capital, and willingness to adapt to FHLAC are 22.24 %, 28.69 %, and 49.07 %, respectively. …”
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