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4761
Triatoma dimidiata, domestic animals and acute Chagas disease: a 10-year follow-up after an eco-bio-social intervention
Published 2025-07-01“…Results Persistent household infestation by T. dimidiata was observed across all four communities, with infestation rates ranging from 17% to 38% and colonization levels ranging from 9% to 29%. …”
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4762
Antidepressant Switching as a Proxy Phenotype for Drug Nonresponse: Investigating Clinical, Demographic, and Genetic Characteristics
Published 2025-07-01“…Background: Selective serotonin reuptake inhibitors (SSRIs) are a first-line pharmacological therapy in major depressive disorder (MDD), but treatment response rates are low. Clinical trials lack the power to study the genetic contribution to SSRI response. …”
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4763
Long-term outcomes of dupilumab therapy in severe asthma: A retrospective, multicenter, real-world study
Published 2025-11-01“…Real-world data on the continuation and cessation patterns of dupilumab and long-term treatment efficacy are scarce. …”
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4764
Oncolytic Vaccinia Virus Armed with GM-CSF and IL-7 Enhances Antitumor Immunity in Pancreatic Cancer
Published 2025-04-01“…The synergistic effects of VVL-GL7 and the PD-1 blockade further improved therapeutic outcomes, resulting in significantly higher tumor remission rates compared to monotherapy and achieving complete tumor regression in pancreatic cancer models. …”
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4765
Spatio-Temporal Characteristics and Driving Forces of Landscape Ecological Risks in Highly Urbanized Areas: A Case Study of Suzhou City
Published 2025-07-01“…However, relatively little attention has been given to urbanized areas characterized by high rates of population growth and land development. …”
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4766
A longitudinal qualitative study of clinical nurses caring for hospitalized adults during the first fifteen months of COVID-19: lessons in professional survival and leadership
Published 2025-08-01“…At the time of this April surge, nurses were exposed to a virus with no standard treatments and high mortality rates. Using a longitudinal qualitative design, the team hoped to answer questions about what compelled these nurses to continue to come to work? …”
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4767
Ten-year trends in opioid prescribing and vaso-occlusive crises in sickle cell disease: a population-based national cohort study (2011–2022)Research in context
Published 2025-10-01“…Primary outcomes were monthly rates of outpatient opioid prescriptions and VOC-related acute care encounters. …”
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4768
Toward improving retention in HIV care after pregnancy: lessons from a post-pandemic cohort in the United States
Published 2025-06-01“…IntroductionPeople living with HIV (PLWH) often experience low rates of retention in HIV care (RIC) and suboptimal viral suppression postpartum. …”
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4769
Seasonal population dynamics and dietary switching of Vulpes spp. amplify Echinococcus spp. transmission in the Eastern Tibetan plateau: implications for wildlife-mediated zoonotic...
Published 2025-07-01“…This dietary diversification correlated with seasonal resource scarcity, driving foxes to exploit alternative prey. The infection rates of Echinococcus in V. ferrilata displayed the U-shaped seasonal patterns. …”
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4770
Decentralized Immunization Monitoring: Lessons Learnt from a Pilot Implementation in Kumbotso LGA, Kano State, Nigeria
Published 2025-06-01“…Univariate and bivariate analyses were performed to show patterns and relations across variables. Results: Out of 418 caregivers surveyed, 98.1% were female. …”
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4771
Preparation of land subsidence susceptibility map using machine learning methods based on decision tree (case study: Isfahan–Borkhar)
Published 2025-09-01“…Studies estimate that approximately 3.5% of Iran's land area has been affected by subsidence, with some regions showing annual sinking rates of over 10 centimeters. Such rates are alarmingly high and have direct implications for urban development, agriculture, and even national heritage conservation. …”
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4772
Risk of developing drug abuse in administration of a new hexaazaisowurtzitane derivative-based analgesic (experimental study)
Published 2022-04-01“…Previous in vivo and in silico studies (docking, molecular modeling, molecular dynamics simulation) on the multi-target mechanism of thiowurtzine explain the absence of its morphine-like effect by the fact that the major targets of the analgesic are TRPA1 receptors and voltage-gated Ca 2+ channels. With a high degree of probability, the conclusions made herein predict no drug abuse development when thiowurtzine is used in the clinical setting. …”
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4773
Geographical variation of overweight, obesity and related risk factors: Findings from the European Health Examination Survey in Luxembourg, 2013-2015.
Published 2018-01-01“…Large disparities in the prevalence of overweight and obesity were found between municipalities, with the highest rates of obesity found in 3 municipalities located in the South-West of the country. …”
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4774
Fertility intentions among Chinese adults: a cross-sectional study using a national survey
Published 2025-08-01“…To tackle the challenge of decreasing fertility rates effectively, it is essential that interventions focus on younger women and highlight the advantages of living with multiple generations. …”
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4775
Levels and types of physical activity in Russia according to the ESSE-RF study: is there a trace of the COVID-19 pandemic?
Published 2023-12-01“…Compared to the urban population, rural residents have higher physical activity rates (23,9 vs 20,3%, p<0,001). The proportion of people with high physical activity is also higher among people with higher income levels (p<0,001). …”
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4776
Dependence of Indicators of Daily Blood Pressure Monitoring on Activity of Pathological Process in Patients with Systemic Lupus Erythematosus
Published 2016-09-01“…According to the first goal was rated the BP in the SLE patients during the period of 24 hours, for which: a) were examined the average daily, maximum and minimum levels of systolic blood pressure (SBP), diastolic blood pressure (DBP), the average blood pressure; b) was analysed the daily index (DI) of SBP, DBP and the average blood pressure; c) was examined the time index (TI) of SBP, DBP and the average blood pressure. …”
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4777
Numerical Simulation Study on the Dynamic Processes and Evolution Laws of Multiple Granular Flows in a Gully
Published 2025-01-01“…Compared with the first granular flow, subsequent ones feature shorter durations and higher energy dissipation rates. The velocity and displacement of base granules increase significantly as the friction coefficient decreases and the secondary slope increases. …”
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4778
Investigation of methicillin, beta lactam, carbapenem, and multidrug resistant bacteria from blood cultures of septicemia suspected patients in Northwest Ethiopia
Published 2025-02-01“…Gram-positive bacteria, particularly S. aureus, and gram-negative bacteria like K. pneumoniae and E. coli were predominant. High rates of methicillin, beta-lactam, and carbapenem resistance were observed, emphasizing the magnitude of antimicrobial resistance. …”
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4779
Googling Patients
Published 2022-11-01“…Numerous wearable devices collect data on consumers’ heart rates, exercise patterns and sleep patterns. In-home smart devices can track when users are active and what they are doing in their homes. …”
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4780
Age and Tumor Stage Interplay in Intrahepatic Cholangiocarcinoma: Prognostic Factors, Mortality Trends, and Therapeutic Implications from a SEER-Based Analysis
Published 2025-01-01“…Furthermore, it examines the clinical features, survival rates, and prognostic indicators of ICC cases diagnosed between 2010 and 2017. …”
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