Real-World Evidence of Safety and Efficacy of Carboplatin plus Nanoparticle Albumin-Bound Paclitaxel in Patients with Advanced Non-Small-Cell Lung Cancer and Preexisting Interstiti... by Tomoyuki Araya, Toshiyuki Kita, Tsukasa Ueda, Nanao Terada, Tamami Sakai, Kenta Yamamura, Koji Kurokawa, Yuka Uchida, Takashi Sone, Hideharu Kimura, Kazuo Kasahara

“…The overall response and disease control rates were 77.8% (95% CI, 40.0–97.2) and 88.9% (95% CI, 51.8–97.2), respectively. …”
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Research on a PCA-transformer-based prediction algorithm for gas concentration in working face by YANG Jian, SHU Longyong, ZHANG Shulin, QIN Kai, CUI Cong

“…Then, PCA was applied to reduce the dimensionality of seven influencing factors (methane concentration at the upper corner, return airflow methane concentration, oxygen concentration, carbon monoxide concentration, temperature, net flow rate, and wind speed), effectively eliminating weakly correlated features. …”
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DiffCoRank: a comprehensive framework for discovering hub genes and differential gene co-expression in brain implant-associated tissue responses by Anirban Chakraborty, Erin K. Purcell, Michael G. Moore

“…A key innovation of our approach is false discovery rate (FDR) based selection of strongly connected genes (SCGs), by which we improve detection of strong coexpression patterns that otherwise could be lost to spurious correlations. …”
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Water production efficiency and economic benefits under diversified planting modes of intercropping-multiple cropping in arid regions. by Na Zhang, Jianxin Jin, Jing Chen

“…It can be seen that diversified planting patterns can improve the yield and economic benefits per unit land area, and are a highly promising planting pattern.…”
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Evaluation of the daily routines and health behaviors of primary school children and their parents: what has changed with a pandemic? by Derya Ceyhan, Betül Karagür Çakmak, Furkan Burkay Gürel

“…For both parents (68.9%) and children (68.5%), the proportion of those who experienced changes in daily routines was high, and who experienced stress due to the pandemic changed their daily routines more (p < 0.01). The rate of unchanged oral hygiene habits was higher for both parents (74.0%) and their children (77.1%). …”
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Analysis of major human and foodborne pathogens and their resistance to antimicrobials in the USA in the past two decades: Implications for surveillance and control of antimicrobia... by PAN Hang, LI Xiaoliang, FANG Weihuan, YUE Min

“…Potential links between consumption of antimicrobials and patterns of antimicrobial resistance were discussed. …”
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Evaluation of Worker Fatigue During Exoskeleton-Assisted Tasks with Varying Intensities by Daehwi Jo, Gu Young Cho, Kyung-In Kang, Hyunsoo Kim

“…Time-series analysis further revealed that exoskeletons not only decrease overall fatigue accumulation but also slow the rate of fatigue increase, extending the period in which workers can maintain safe and efficient movement patterns. …”
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Contemporary problems of budget development of regional centers by M. A. Pechenskaya

“…It is shown that the risk of budget reduction in the social sphere and economy financing increased due to the growing cost of servicing municipal debt, which in the North-Western federal district regional centers increased 14 times in 2011-2018, while the average growth in Russia in that period was four-fold. The increase in the rate of budget expenditures centralization was revealed, which was manifested in an eight-fold increase in the delegated authority from higher levels to the budgets of regional centers of the North-Western federal district in 2011-2018.Scientific novelty: modern patterns of budget systems development of regional centers of Russia and the North-Western federal district are defined and justified, in particular for 2011-2018.Practical significance: the materials of the article can be used by professors of higher educational institutions in the educational process, and by researchers as a research base. …”
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Electricity Theft Detection Using Rule-Based Machine Leaning (rML) Approach by Sheyda Bahrami, Erol Yumuk, Alper Kerem, Beytullah Topçu, Ahmetcan Kaya

“…With an astounding 93% recall rate for the rule-based feature space combination of the random forest classifier, this novel approach has produced outstanding results. …”
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A multimodal functional structure-based graph neural network for fatigue detection by Dongrui Gao, Zhihong Zhou, Zongyao Peng, Haokai Zhang, Shihong Liu, Manqing Wang, Hongli Chang

“…The framework employs differential entropy (DE) features extracted from filtered EEG signals and heart rate variability (HRV) features derived from ECG signals as dual input streams, capturing distinct internal–external interaction patterns. …”
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Impact of stratifin/14-3-3σ on survival and interstitial lung disease in patients with non-small cell lung cancer receiving immune checkpoint inhibitors by Daiki Murata, Koichi Azuma, Kenta Murotani, Yoshiaki Zaizen, Tomoaki Hoshino

“…Meanwhile, delta-SFN, representing the change in SFN values between ICI initiation and at the 6-week point, was associated with progression-free survival, overall survival, disease control rate, and ICI-ILD image patterns. Conclusion SFN levels in plasma were associated with therapeutic efficacy and ICI-ILD pattern in patients with NSCLC receiving cancer immunotherapy. …”
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Radiocleavable rare-earth nanoactivators targeting over-expressed folate receptors induce mitochondrial dysfunction and remodel immune suppressive microenvironment in pancreatic ca... by Tanvi Gupta, Shang-Rung Wu, Li-Chan Chang, Forn-Chia Lin, Yan-Shen Shan, Chen-Sheng Yeh, Wen-Pin Su

“…Abstract Pancreatic cancer is a fatal cancer with poor prognosis and survival rate, often diagnosed usually in the advanced stage of disease. …”
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Burden and Outcomes of Severe Lower Respiratory Tract Infections with Unknown Etiology: A Retrospective Observational Study on Epidemiological Trends Over an 8-Year Period (2016–20... by Giovanni Scaglione, Marta Canuti, Martina Offer, Valentina Breschi, Antonio Piralla, Fausto Baldanti, Gabriele Del Castillo, Francesco Scovenna, Sabrina Buoro, Federica Morani, Danilo Cereda, Alessandra Bandera, Andrea Gori, Marta Colaneri

“…Results Among 683,741 hospitalizations, 338,211 (49.5%) were of unknown etiology, showing a 12.3% intra-hospital mortality rate (41,627 deaths) and 4.0% intensive care unit admission rate (13,625 admissions). …”
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Differences in geochemical characteristics of produced water from coalbed methane wells and their indications for drainage：A case study of the Santang Syncline in Western Guizhou by Xiaozhi ZHOU, Shuaiqi WANG, Shiliang ZHU, Shaolei WANG, Gang XIANG, Xuehua CHEN, Jihang DONG, Xin QIU

“…Combined with the monitoring of the water quality and hydrochemical characteristics of the produced water from CBM wells, the overflow release process after fracturing is divided into four stages: trial flowback, constant-rate flowback, slow increase of the flowback rate, and rapid decrease of the flowback rate. …”
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Bacterial Resistance in Ophthalmology – Resistance Profile, Influencing Factors and Prevention Methods. A Review by Matei POPA-CHERECHEANU, Alina POPA-CHERECHEANU, Dan George DELEANU, Mihai Aurelian GHITA

“…It is hoped that future reports show good results without the use of antibiotics will encourage ophthalmologists to limit the use of topical antibiotics, reducing the rate of antimicrobial resistance.…”
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MtDNA copy number enrichment is associated with poor prognosis and eosinophilic morphology in clear cell renal cell carcinoma by Sarah Bellal, Sarah Bellal, Cyrielle Rolley, Jeremy Richard, Nolwenn Bounaix, Vincent Le Corre, Marie-Christine Copin, Odile Blanchet, Pierre Bigot, Pierre Bigot, Vincent Procaccio, Vincent Procaccio, Céline Bris, Céline Bris

“…CSS was significantly reduced in the “HIGH” than in the “LOW” group with respective 5-year survival rates: 78.7% (CI 95: 64.8–95.5) and 95.5% (CI 95 87.1–100.0) (Hazard Ratio: 7.4 (CI 95: 1.9–29.9, p = 0.027*) in multivariate analysis, including pathological classification, tumor size, International Society of Urological Pathology grade, lymphovascular invasion, dedifferentiated pattern, necrosis and adjuvant therapy. …”
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Machine learning and microfluidic integration for oocyte quality prediction by Hassan Saffari, Davood Fathi, Peyman Palay, Hamid Gourabi, Rouhollah Fathi

“…Additionally, oocyte diameter and the critical flow rate (Q)—defined as the minimum flow rate necessary for an oocyte to pass through the channel—were included as predictive variables. …”
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Identification and Validation of the lncRNA BACE1-AS as Immune-Related Influencing Factor in Tumorigenesis following Pan-Carcinoma Analysis by Mengmeng Wang, Di Chen, Yushuang Xu, Mengjun Qiu, Xin Jiang, Zhifan Xiong

“…Overall, our results suggest that BACE1-AS is associated with the expression, prognosis, and rate of immune cell infiltration of most tumors. …”
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Spatial proximity effects on cognitive processing of multimedia learning among college students: evidence from functional near-infrared spectroscopy by Yan Ma, Yan Ma, Qiuyue Peng, Qiuyue Peng, Bowen Long, Bowen Long

“…In addition, the study also explored how disciplinary differences affect the strength of spatial proximity effects and corresponding brain activation patterns.ResultsThe findings revealed that activation levels in the middle temporal gyrus, frontal pole, and dorsolateral prefrontal cortex were significantly higher in the spatial proximity condition compared to the spatial separation condition, accompanied by an improved rate of correct answers. …”
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The 'Antiretrovirals, Sexual Transmission Risk and Attitudes' (ASTRA) study. Design, methods and participant characteristics. by Andrew Speakman, Alison Rodger, Andrew N Phillips, Richard Gilson, Margaret Johnson, Martin Fisher, Ed Wilkins, Jane Anderson, Rebecca O'Connell, Monica Lascar, Kazeem Aderogba, Simon Edwards, Jeffrey McDonnell, Nicky Perry, Lorraine Sherr, Simon Collins, Graham Hart, Anne M Johnson, Alec Miners, Jonathan Elford, Anna-Maria Geretti, William J Burman, Fiona C Lampe

“…In this paper we describe the study rationale, design, methods, response rate and the demographic characteristics of the participants. …”
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