Loss of <i>Myostatin</i> Shapes the Transcriptomic and Epigenetic Landscapes Across Multiple Muscle Types in Cattle by Chao Hai, Xuefei Liu, Chunling Bai, Guanghua Su, Lei Yang, Guangpeng Li

“…The results showed that the <i>MSTN</i> gene-edited (MT) cattle skeletal muscle exhibited significantly larger myofiber cross-sectional areas (<i>p</i> = 0.049), accompanied by reduced shear force (<i>p</i> = 0.044), cooking loss rate (<i>p</i> = 0.0029), and pH (<i>p</i> = 0.014). …”
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A randomized controlled trial of timing and dosage of upper extremity rehabilitation in virtual environments in persons with subacute stroke by Jigna Patel, Qinyin Qiu, Gerard G Fluet, Holly Gorin, Jennifer Gutterman, Kiran Karunakaran, Karen J Nolan, Emma Kaplan, Alma S Merians, Sergei V Adamovich

“…At 4 months post stroke the DVR group showed a higher rate of change from baseline on the Action Research Arm Test compared to the EVR group. …”
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A Lower Energy Balance is Associated With Higher Severity and Odd of Depression Based on the Beck Depression Inventory‐13 (BDI‐13) in a Retiring Age Population: A Population‐Based... by Mohammad Reza Shadmand Foumani Moghadam, Mostafa Shahraki Jazinaki, Zohre Hosseini, Fatemeh Rajabi, Sharif Etemdi, Melika Hadizadeh, Parnian Pezeshki, Mohammad Amushahi, Reza Rezvani

“…Energy balance was calculated by subtracting energy intake from Total Energy Expenditure (TEE) and Basal Metabolic Rate (BMR) which was calculated using Bio‐Electrical Impedance Analysis and Mifflin and St‐Jeor formula. …”
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Multivariate Evaluation of Flash Drought Across the United States by Jason A. Otkin, Yafang Zhong, Trent W. Ford, Martha C. Anderson, Christopher Hain, Andrew Hoell, Mark Svoboda, Hailan Wang

“…The FDII method uses the rate of intensification (FD‐INT) and subsequent drought severity (DRO‐SEV) to determine when a flash drought occurred and the strength of the event. …”
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Climate Change and Its Impacts on the Planting Regionalization of Potato in Gansu Province, China by Yulan Lu, Junying Han, Guang Li, Zhengang Yan, Lixia Dong, Zhigang Nie, Qiang Liu

“…The average temperature in July showed a decreasing spatial pattern from northeast to southwest, while its tendency rate showed a decreasing trend from west to east and from north to south. …”
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An integrative scoring approach for prioritization of rare autism spectrum disorder candidate variants from whole exome sequencing data by Apurba Shil, Noa Arava, Noam Levi, Liron Levine, Hava Golan, Gal Meiri, Analya Michaelovski, Yair Tsadaka, Adi Aran, Idan Menashe

“…We developed AutScore and AutScore.r and assigned each variant based on their pathogenicity, clinical relevance, gene-disease association, and inheritance patterns. Finally, we compared the performance of both AutScore versions with the rating of clinical experts and the NDD variant prioritization algorithm, AutoCaSc. …”
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Psychological, social factors, and smoking behavior mediated the effects of cannabis use on personality disorders: A Mendelian randomization study by Yao Ni, Juanmei Li, Zitian Tang, Youqian Zhang, Yanyan Feng

“…BackgroundRapid changes in attitudes, legality, and patterns of cannabis use (CU) underscore the importance of understanding its impact on mental health. …”
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Repurposing of CNS accumulating drugs Gemfibrozil and Doxylamine for enhanced sensitization of glioblastoma cells through modulation of autophagy by Smita Dey, Prerika Mathur, Sudeshna Mukherjee, Rajdeep Chowdhury, Syamantak Majumder, Aniruddha Roy, Shibasish Chowdhury

“…Abstract GBM is one of the most aggressive malignancies, having the greatest fatality rate and average life years lost. The current standard medicine, temozolomide (TMZ), is ineffective, requiring the development of new treatments. …”
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Cyclical short‐term fasting and refeeding effects on immunological alteration of the disk abalone, Haliotis discus discus by Dien Arista Anggorowati, Liqing Zang, Yutaka Tamaru, Takahiko Aoki, Fumiyoshi Okazaki

“…We measured survival and growth rate as well as analysed immunological parameters, such as total haemocyte count, phenoloxidase activity, respiratory burst activity, lysozyme activity and protein content across the groups. …”
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Different functions of PHF10 isoforms – subunits of the PBAF chromatin remodeling complex by A. A. Sheynov, V. V. Tatarskiy, A. M. Azieva, S. G. Georgieva, N. V. Soshnikova

“…Stability can alter the turnover rate of the subunits of the PBAF complex. All PHF10 isoforms are degraded by β-TrCP ubiquitin ligase but PHF10-S isoforms contain a cluster of serins (X-cluster) for multiple phosphorylation by casein kinase I. …”
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Parasitic infections and the development of endomyocardial fibrosis: systematic review of case reports and case series by Abel Aizeque, Alex Mwangi Kihunyu, Olamide Daniel Odusola, Sulymon A. Saka, Abdinasir Mohamed Aray

“…Treatment mainly consisted of antiparasitic therapy and diuretics, with a survival rate of 50%, while 19% (3/16) of patients died from multi-organ failure and thromboembolic complications. …”
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Are HIV epidemics among men who have sex with men emerging in the Middle East and North Africa?: a systematic review and data synthesis. by Ghina Mumtaz, Nahla Hilmi, Willi McFarland, Rachel L Kaplan, Francisca Ayodeji Akala, Iris Semini, Gabriele Riedner, Oussama Tawil, David Wilson, Laith J Abu-Raddad

“…The high levels of risk behavior (4-14 partners on average in the last six months among different MSM populations) and of biomarkers of risks (such as herpes simplex virus type 2 at 3%-54%), the overall low rate of consistent condom use (generally below 25%), the relative frequency of male sex work (20%-76%), and the substantial overlap with heterosexual risk behavior and injecting drug use suggest potential for further spread.…”
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Geographical variation in antimicrobial use and multiresistant pathogens in Brazilian intensive care units: a nationwide study by Alice Ramos Oliveira Silva, Constanza Xavier Borges Barbosa, Raianne Soares Rebelo, Fernando Fernandez-Llimos, Elisangela Costa Lima

“…We measured antimicrobial use and CLABSI trends per ICU bed using the compound annual growth rate (CAGR). Results: we evaluated the regional variation in CLABSI by multidrug-resistant pathogens and the antimicrobial use in 1,836 hospital intensive care units (ICUs). …”
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Integrated analysis of the functions and prognostic values of RNA-binding proteins in neuroblastoma. by Jun Yang, Jiaying Zhou, Cuili Li, Shaohua Wang

“…There were significant differences in the survival rate of patients in the high and low-risk subgroups in the validation data set GSE85047 (P = 0.1237e-08), with the AUC 0.730. …”
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Optimal Skin Prick Test Panel for Detecting Respiratory Allergens in Children: A Retrospective Study by Aykut Eşki, Gökçen Kartal Öztürk, Figen Gülen, Esen Demir

“…Different allergen sensitization patterns have been observed within countries and regions according to geographical and seasonal variations. …”
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A Deep Learning Approach for Extracting Cyanobacterial Blooms in Eutrophic Lakes From Satellite Imagery by Nan Wang, Zhenyu Tan, Chen Yang, Jinge Ma, Hongtao Duan

“…MBAUNet also effectively distinguished aquatic vegetation, turbid waters, clouds, and low-density CyanoHABs, maintaining a low error rate of 5.8% across varied environments. When applied to other lakes, MBAUNet consistently delivered over 90% precision. …”
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Outlook for Neurofi bromatosis Type I Research in the Republic of Bashkortostan by R. N. Mustafin, E. K. Khusnutdinova

“…Average worldwide incidence rate of NF1 is 1:3000, equal in men and women. Th e disease develops with a heterozygous mutation in the oncosupressor neurofi bromin-encoding gene NF1. …”
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Clinical Features and Surgical Management of Bile Duct Cyst in Adults by Xin Wu, Binglu Li, Chaoji Zheng, Xiaodong He

“…There was no significant difference in the postoperative complication rate between the two groups. Ninety-four patients were followed up for 37.8±23.8 months, and BDI occurred in 33 patients (35.1%). …”
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Detection and genetic diversity of Neoehrlichia mikurensis in rodents from central and southern Shanxi, China by Hongbing Cheng, Jingrong Niu, Yiping Liu, Fei Ren, Chao Zhao, Jia Cui, Yuzan Bai, Yunxia Chen, Juan Yu, Huaxiang Rao

“…N. mikurensis was detected in Apodemus agrarius from Yangquan and Eothenomys inez from Yuncheng, with a positivity rate of 0.66% (2/301). Phylogenetic analysis based on 16 S rRNA and groEL genes revealed that the sequences in this study formed distinct branches separate from reported clusters (Clusters I-IV), clustered near Clusters III and IV, which the pathogenicity was unclear. …”
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Sex differences in DNA methylation variations according to ART conception-evidence from the Norwegian mother, father, and child cohort study by Dana Kristjansson, Yunsung Lee, Christian M. Page, Håkon Gjessing, Maria C. Magnus, Astanand Jugessur, Robert Lyle, Siri E. Håberg

“…We identified 37 differentially methylated CpGs according to ART-conception among girls, and 70 differentially methylated CpGs according to ART-conception among boys, when we used a 1% false discovery rate to account for multiple testing. Ten CpGs were differentially methylated according to conception by ART in both sexes. …”
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