Ultrasound Stimulations Induce Prolonged Depolarization and Fast Action Potentials in Leech Neurons by Francesca Dedola, Francesco Paolo Ulloa Severino, Nicolo Meneghetti, Theo Lemaire, Andrea Cafarelli, Leonardo Ricotti, Arianna Menciassi, Annarita Cutrone, Alberto Mazzoni, Silvestro Micera

“…Moreover, we found that APs induced by US differ in smaller amplitude and faster repolarization from those induced by electrical stimulation in the same cell but display the same repolarization rate. <italic>Conclusions:</italic> These results shed light on the mechanism by which spikes are induced by US and pave the way for designing more efficient US stimulation patterns.…”
Get full text

Spatial Heterogeneity of Bike-Sharing–Conventional Bus Intermodal Trip Distribution by Yang Chenyang, Tang Wenyun, Ma Jianxiao, Yin Chaoying, Wang Hanbin

“…The results indicated that the density of bike-sharing trips near bus stops followed a consistent pattern. The density decreases with increasing distance from the stop, and the rate of decline exhibits a "U-shaped" pattern. …”
Get full text

Systemic hormonal contraception and risk of venous thromboembolism by Oskari Heikinheimo, Elena Toffol, Timo Partonen, Anna But, Antti Latvala, Jari Haukka

“…Results Altogether, 1334 venous thromboembolism cases occurred during the follow‐up period (incidence rate 1.14 per 1000 person‐years, 95% confidence interval [CI] 1.08–1.20), with an incidence rate ratio of hormonal contraception vs no hormonal contraception use of 1.42 (95% CI 1.27–1.58). …”
Get full text

Translating weighted probabilistic bits to synthetic genetic circuits by Matthew D. Ciccone, Carlos D. Messina

“…We analyze the necessary requirements for assuring Boolean logic gate sequences can function in unpredictable intracellular conditions, followed by interpreted pathways by which a mathematical representation of probabilistic circuits can be translated to biological implementation. …”
Get full text

Multimodal analysis of cell-free DNA enhances differentiation of early-stage breast cancer from benign lesions and healthy individuals by Thi Tuong Vi Van, Trung Hieu Tran, Thi Hue Hanh Nguyen, Van Thien Chi Nguyen, Dac Ho Vo, Giang Thi Huong Nguyen, Trong Hieu Nguyen, Kim Sang To, Anh Luan Nguyen, Cao Hong An Tran, Thanh Xuan Jasmine, Thi Loan Vo, Thi Huong Thoang Nai, Thuy Trang Tran, My Hoang Truong, Ngan Chau Tran, Thi Loc Le, Thi Hong Nhung Nguyen, Ngoc Hieu Tu, Thanh Son Tran, Bao Toan Le, Van Phong Tang, Pham Thanh Nhan Nguyen, Khac Tien Nguyen, Van Chien Ho, Xuan Vinh Nguyen, Nhu Nhat Tan Doan, Thi Trang Tran, Thi Minh Thu Tran, Vu Uyen Tran, Minh Phong Le, Thi Luyen Vu, Ba Linh Tieu, Huu Tam Phuc Nguyen, Luu Hong Dang Nguyen, Ngoc Minh Phan, Thi Van Phan, Thi Thanh Thuy Do, Thi Huyen Dao, Hung Sang Tang, Duy Sinh Nguyen, Hoa Giang, Minh Duy Phan, Hoai-Nghia Nguyen, Duc Hieu Vo, Le Son Tran

“…Conclusions These findings underscore the potential of cfDNA biomarkers to enhance BC detection and reduce the rate of unnecessary biopsies.…”
Get full text

Brain-based gene expression and corresponding behavioural relevance of risk genes for broad antisocial behaviour by Jaroslav Rokicki, Megan L. Campbell, Dennis van der Meer, Alina I. Sartorius, Natalia Tesli, Piotr Jahołkowski, Alexey Shadrin, Ole Andreassen, Lars T. Westlye, Daniel S. Quintana, Unn K. Haukvik

“…Certain genes like NTN1, SMAD5, NCAM2, and CDC42EP3 displayed specificity for cognitive terms including chronic pain, heart rate, and aphasia. These expression patterns aligned with neurocognitive domains related to thinking, and learning, distress, motor skills, as determined by fMRI analysis. …”
Get full text

Research on process optimization and trajectory planning of EA4T axle robot grinding by Feng ZHANG, Zhongli FENG, Feng XU, Deming ZHANG, Xiangrui ZENG, Jianwei MA, Shilei ZHANG

“…The grinding force, feed rate and spindle speed corresponding to the optimal grinding process parameters are entered into the control system. …”
Get full text

Developing a molecular diagnostic model for heatstroke-induced coagulopathy: a proteomics and metabolomics approach by Qingbo Zeng, Qingwei Lin, Longping He, Lincui Zhong, Ye Zhou, Xingping Deng, Nianqing Zhang, Qing Song, Qing Song, Jingchun Song, Jingchun Song

“…Significant differences were observed between the groups in temperature, heart rate, white blood cell count, platelet count, liver function, coagulation markers, APACHE II score, and GCS score. …”
Get full text

Functional Connectivity Biomarker Extraction for Schizophrenia Based on Energy Landscape Machine Learning Techniques by Janerra D. Allen, Sravani Varanasi, Fei Han, L. Elliot Hong, Fow-Sen Choa

“…However, significant patient and control differences were found for the brief psychiatric rating scale (BPRS), auditory perceptual trait and state (APTS), visual perceptual trait and state (VPTS), working memory score, and processing speed score. …”
Get full text

Longitudinal trajectories of disability index and associated factors in Chinese older adults by Huaxin Si, Yemin Yuan, Zhenyu Shi, Yanshang Wang, Ping He

“…This study aimed to identify patterns of disability index trajectories and associated factors influencing these trajectories in older adults. …”
Get full text

Clustering analysis of volatile organic compound biomarkers with tobacco exposure and the association with cardiovascular health outcomes in an observation study cohort by Juan Zhao, Haoyun Hong, Joseph Zhai, Remy Poudel, Sanjay Srivastava, Andrew C. Stokes, Pawel K. Lorkiewicz, Tian Jiang, Rose Marie Robertson, Aruni Bhatnagar, Jennifer L. Hall, Naomi M. Hamburg, Rachel J. Keith

“…After adjustment for age, sex, and race, Cluster 2 was associated with a higher heart rate (β=3.29; 95% CI: -0.26–6.84; p<0.05) compared to Cluster 1. …”
Get full text

Identification of biomarkers for Laryngeal squamous cell carcinoma through Mendelian randomization and integrated bioinformatics analysis by Pengjian Zhang, Weizhang Chen, Kai Chen, Yuanhang Ye, Weijun Wu

“…Abstract Background Laryngeal squamous cell carcinoma (LSCC) is a common head and neck tumor with an increasing incidence rate and limited therapeutic efficacy in advanced stages. …”
Get full text

Paradox of Low CA-125 in Patients with Decompensated Congestive Heart Failure by Raquel López-Vilella, Borja Guerrero Cervera, Víctor Donoso Trenado, Julia Martínez-Solé, Sara Huélamo Montoro, Valero Soriano Alfonso, Franco Appiani, Luis Martínez Dolz, Luis Almenar-Bonet

“…Scheduled admissions, transfers from other hospitals, pulmonary congestion patterns, mixed patterns, and low output were the exclusion criteria. …”
Get full text

SUSCEPTIBLE VACCINATED INFECTED RECOVERED MODEL WITH THE EXCLUSIVE BREASTFEEDING AND ITS APPLICATION TO PNEUMONIA DATA IN INDONESIA by Purnami Widyaningsih, Ghufron Musta'in, Dewi Retno Sari Saputro

“…The free target can also be achieved by increasing the exclusive breastfeeding rate to 73.9% and the Hib vaccination rate to 0.22.…”
Get full text

Ecological drivers of nesting behavior in a subtropical city: An observational study on spotted doves by Yao Sheng, Mengjie Lu, Junpeng Bai, Xiaobin Xie, Long Ma, Wanyou Li, Zhen Zhang, Fang Ming, Xueli Zhang, Ziwei Zhang, Zhifeng Xu, Yuqing Han, Bicai Guan, Luzhang Ruan

“…The results revealed that the nest reuse rate was 38.08% (n = 115). Nests closer to trunk, with lower nest position and higher large‐scale urbanization score tended to have higher reuse rate. …”
Get full text

Directly Fabricated Flexible Photodetector Based on TiO&#x2082;-Doped Carbon Nanosheets Film by Yunlong Zhang, Xiaolin Li, Zhipeng Cao, Qiang Wu, Gong Chen, Bo Wen, Dongfeng Diao, Xi Zhang

“…The edge states suppress the recombination rate of photo-generated electron-hole pairs, thereby significantly enhancing the photo-responsive performance. …”
Get full text

Thermal comfort and energy related occupancy behavior in Dutch residential dwellings by Anastasios Ioannou

“…Specifically in houses with a good energy rating, the neutral temperature was higher than in houses with a poor rating. …”
Get full text

Identification of novel diagnostic and prognostic microRNAs in sarcoma on TCGA dataset: bioinformatics and machine learning approach by Rahem Rahmati, Fatemeh Zarimeidani, Farnaz Ahmadi, Hannaneh Yousefi-Koma, Abdolreza Mohammadnia, Maryam Hajimoradi, Shadi Shafaghi, Elham Nazari

“…We identified a significant association between the overall survival rate of sarcoma patients and miRs levels. The combination of miR.3688 and miR.3936 achieved the greatest diagnostic standing. …”
Get full text

An integrative scoring approach for prioritization of rare autism spectrum disorder candidate variants from whole exome sequencing data by Apurba Shil, Noa Arava, Noam Levi, Liron Levine, Hava Golan, Gal Meiri, Analya Michaelovski, Yair Tsadaka, Adi Aran, Idan Menashe

“…We developed AutScore and AutScore.r and assigned each variant based on their pathogenicity, clinical relevance, gene-disease association, and inheritance patterns. Finally, we compared the performance of both AutScore versions with the rating of clinical experts and the NDD variant prioritization algorithm, AutoCaSc. …”
Get full text

Analysis of Effects of Rough Strip Energy Dissipator on Hydraulic Property of Bend Flow by Honghong Zhang, Zhenwei Mu, Fan Fan, Fanqi Li

“…The energy dissipation rate of the R-SED decreased with an increase in discharge flow rate and ranged between 30% and 50%. …”
Get full text