Identification of CaVβ1 Isoforms Required for Neuromuscular Junction Formation and Maintenance by Amélie Vergnol, Aly Bourguiba, Stephanie Bauché, Massiré Traoré, Maxime Gelin, Christel Gentil, Sonia Pezet, Lucile Saillard, Pierre Meunier, Mégane Lemaitre, Julianne Perronnet, Frederic Tores, Candice Gautier, Zoheir Guesmia, Eric Allemand, Eric Batsché, France Pietri-Rouxel, Sestina Falcone

“…Voltage-gated Ca²⁺ channels (VGCCs) are regulated by four CaVβ subunits (CaVβ1–CaVβ4), each showing specific expression patterns in excitable cells. …”
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Analysis of the molecular nature associated with microsatellite status in colon cancer identifies clinical implications for immunotherapy by Wei Wu, Qihan Fu, Lulu Liu, Yi Zheng, Hangyu Zhang, Peng Zhao, Weijia Fang, Xuanwen Bao, Shaobing Cheng, Xiaomeng Dai, Xudong Zhu, Zhou Tong, Fanglong Liu

“…A receiver operating characteristic curve was used to evaluate the accuracy rate of neural network, reaching 100%.Conclusion Our analysis unraveled the difference in the molecular nature and genomic variance in MSI and MSS colon cancer. …”
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Viral characterization of the reassortants between canine influenza H3N2 and human pandemic (2009) H1N1 and avian H9N2 viruses in canine ex vivo tracheal explants by Tonia T. Kam, Christine H. T. Bui, Hin-Wo Yeung, Peter C. H. Wong, Alex W. H. Chin, John M. Nicholls, Malik Peiris, Kenrie P. Y. Hui, Leo L. M. Poon, Michael C. W. Chan

“…Results Co-passaging H3N2-CIV with human/avian influenza A viruses in canine tracheal explants resulted in a high rate of reassortment. Plaque-purified reassortants were all viable and able to propagate in mammalian alveolar epithelial cells. …”
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Overweight and Helicobacter pylori infection: a correlation in metabolic dysfunction-associated fatty liver disease by Xu Chen, Jiayue Fu, Jiayue Fu, Kejia Jin, Kejia Jin, Zixuan Yang, Zixuan Yang, Yidan Qian, Yidan Qian, Kehan Mei, Yihan Wang, Jialei Min, Yilin Du, Zaisheng Zhu, Zaisheng Zhu, Shengcun Li, Shengcun Li

“…Therefore, eradication of H. pylori infection may have positive implications for reducing the incidence rate of overweight MAFLD.…”
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IMPACT OF THE INFLAMMATORY AND ISCHEMIC HEART DISEASE MARKERS INTO THE OVERALL CARDIOVASCULAR MORTALITY IN SENILE CITIZENS OF A LARGE CITY (THE DATA FROM SAHR TRIAL) by S. A. Shalnova, S. E. Evstifeeva, A. D. Deev, V. A. Metelskaya, A. V. Kapustina, G. A. Muromtseva, Yu. A. Balanova, E. M. Tuaeva, A. E. Imajeva, N. V. Kiseleva, M. A. Shkolnikova

“…For the assessment of current subclinical inflammation we used high-sensititvity C-reactive protein (hsCRP), interleucine 6 (IL-6), fibrinogen (FG), leucocytes, erythrocyte sedimentation rate (ESR). For CHD screening, we used standard ROse questionnaire and ECG pattern by Minnesota coding. …”
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A clinico-epidemiological study, assessing possible predictors of mortality and health-related quality of life for people living with visceral leishmaniasis – human immune virus (V... by Niyamat Ali Siddiqui, Dhruv Kumar Pandey, Ashish Kumar Singh, Sanjay Kumar Sinha, Mohd. Zahid Ansari, Rishikesh Kumar, Biplab Pal, Vidya Nand Rabi Das, Rajatashuvra Adhikary, Saurabh Jain, Krishna Pandey

“…These patients have a poor VL therapeutic success rate, more drug-related toxicity, and relapses resulting in high mortality. …”
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Clinical characteristics and outcomes of COVID-19 in kidney transplant recipients by R. O. Kantariya, Ya. G. Moysyuk, E. I. Prokopenko, A. R. Karapityan, A. A. Ammosov, A. V. Makevnina, A. A. Gaydarova

“…The comparison study of the clinical pattern, laboratory and instrumental test results, treatment features and outcomes was made.Results. …”
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Clinical profiles of SS-ILD compared with SS-NILD in a Chinese population: a retrospective analysis of 735 patients by Ting Guo, Yaomei Long, Qinxue Shen, Wei Guo, Wang Duan, Xiaoli Ouyang, Hong Peng

“…NSIP (56.3%) was the most frequent HRCT pattern. Compared with pSS patients with ILD (pSS-ILD) patients, sSS patients with ILD (sSS-ILD) patients had a higher incidence of proteinuria (p < .001) and hypercreatinaemia (p = .013), a higher level of erythrocyte sedimentation rate (ESR) (p = .003), low levels of complement 3 (C3) (p = .013), lymphocytes (p = .009) and leukocytes (p = .024), and worse DLCO (%Pred) (p = .035).Conclusions ILD is a common pulmonary involvement in both pSS patients and sSS patients. …”
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CONCOMITANT CARDIOVASCULAR DISEASES AND ANTIHYPERTENSIVE TREATMENT IN OUTPATIENT PRACTICE (BY THE RECVASA REGISTRY DATA) by M. M. Loukianov, S. A. Boytsov, S. S. Yakushin, S. Yu. Martsevich, A. N. Vorobyev, A. V. Zagrebelnyy, N. N. Nikulina, K. G. Pereverzeva, E. A. Pravkina, A. D. Deev, E. V. Kudryashov, E. N. Belova

“…The mean number of prescribed AHDs was 1.73. The mean incidence rate of target blood pressure achievement was 26.1%. …”
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Ornidazole-Induced Liver Injury: The Clinical Characterization of a Rare Adverse Reaction and Its Implications from a Multicenter Study by Ali Rıza Çalışkan, Ilker Turan, Sezgin Vatansever, Jasmin Weninger, Emine Türkmen Şamdancı, Ayşe Nur Akatli, Elvan Işık, Esra Durmazer, Ayşenur Arslan, Nilay Danış, Hüseyin Kaçmaz, Sedat Cicek, Osman Sağlam, Dilara Turan Gökçe, Derya Arı, Sevinç Tuğçe Güvenir, Serkan Yaraş, Cumali Efe, Meral Akdoğan Kayhan, Murat Harputluoğlu, Ali Canbay, Ulus Salih Akarca, Zeki Karasu, Ramazan Idilman, Fulya Günşar

“…Corticosteroids were used in 24.8% of cases (n = 25) and were associated with higher ANA positivity and a 20% (n = 5) relapse rate post-discontinuation. Recovery was achieved in 87.7% of cases (n = 88), while 7.9% of cases (n = 8) required liver transplantation and 4% (n = 4) died. …”
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Dietary supplementation with L-carnitine elevates intracellular carnitine levels and affects gene expression of SLC25A20 and COX4I1, as well as non-mitochondrial respiration of bov... by Leonie Seemann, Susanne Kersten, Susanne Bühler, Fabian Billenkamp, Ulrich Meyer, Christian Visscher, Korinna Huber, Erika Most, Klaus Eder, Sven Dänicke, Jana Frahm

“…The same applied for PBMC mitochondrial functionality and metabolic activity as assessed by ex vivo approaches, whereas non-mitochondrial respiration rate was significantly affected by L-carnitine supplementation over time. …”
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hnRNPA2B1 recognizes RNA virus SFTSV infection through mitochondrial DNA by Xin-bo Huang, Yue Zhang, Jing-wen Fan, Xin-yu Yu, Yun-lan Fang, Jin-xin Ren, Bin-yan Liu

“…However, it remains largely unclear whether A2B1 could function as a nucleic acid pattern-recognition receptor during cytoplasmic RNA virus infection. …”
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Type II diabetes in systemic sclerosis patients: insights from an observational, multicenter study of GIRRCS (Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale) by Vasiliki Liakouli, Giulio Forte, Piero Ruscitti, Luca Navarini, Francesca Bellisai, Francesco Caso, Giuliana Guggino, Lidia La Barbera, Chiara Rizzo, Ada Corrado, Paola Triggianese, Alberto Lo Gullo, Giuseppe Mandraffino, Luca Cantarini, Bruno Frediani, Paola Cipriani, Francesco Paolo Cantatore, Maria Sole Chimenti, Elvira Favoino, Federico Perosa, Annamaria Iagnocco, Roberto Giacomelli, Francesco Ciccia

“…SSc patients with T2D were significantly older (P < 0.007) and exhibited: higher prevalence of late-stage capillaroscopic pattern (P < 0.001), severe reduction in forced vital capacity (FVC < 50%; P < 0.000), moderate reduction in total lung capacity (TLC 50–69%; P < 0.011), electrocardiographic signs of right ventricular hypertrophy (P < 0.018), higher prevalence of pulmonary arterial hypertension (PAH) confirmed by right heart catheterization (RHC) (P < 0.037) and higher prevalence scleroderma renal crisis (SRC) (P < 0.001); elevated erythrocyte sedimentation rate (ESR) (P < 0.022), and ANA positivity. …”
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Dependence of Indicators of Daily Blood Pressure Monitoring on Activity of Pathological Process in Patients with Systemic Lupus Erythematosus by Abrahamovych O., Abrahamovych U., Kushyna A., Guta S., Synenkyi O.

“…According to the first goal was rated the BP in the SLE patients during the period of 24 hours, for which: a) were examined the average daily, maximum and minimum levels of systolic blood pressure (SBP), diastolic blood pressure (DBP), the average blood pressure; b) was analysed the daily index (DI) of SBP, DBP and the average blood pressure; c) was examined the time index (TI) of SBP, DBP and the average blood pressure. …”
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Silent Revolution in Research for Sustainability by Bruce Alder

“…A variety of new arrangements have come into existence that promote international collaboration, including Horizon 2020 with its emphasis on societal challenges, the Bill &amp; Melinda Gates Foundation which has inspired a family of grand challenges funds on health and development, and the Future Earth joint program of research for global sustainability. …”
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Sewage sludge from Taxco de Alarcón wastewater treatment plant as substrate to cultivate Panicum maximum by Erik Yoel Carreto-Morales, Jazmin Alaide López-Díaz, Mariana Martínez-Castrejón, Oscar Talavera-Mendoza, Roberto Carlos Almazán-Núñez, Giovanni Hernández-Flores

“…The response variables analyzed for MG were germination time (one month after plant emergence), height (HMG), growth rate GrMG, and yield (YMG), whereas in the SS and PS the content of organic matter was analyzed. …”
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Diffusion and Risks of House Prices in the Netherlands by Alfred Larm Teye

“… The rate of home-ownership has increased significantly in many countries over the past decades. …”
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Regional lymph node invasion in pediatric non-rhabdomyosarcoma soft tissue sarcoma: an international cohort study from the International Soft Tissue Sarcoma ConsortiumResearch in c... by Daniel Orbach, Matthieu Carton, Amadeus T. Heinz, Lise Borgwardt, J Herve Brisse, Carlo Morosi, Erin R. Rudzinski, Akmal Safwat, Monika Sparber-Sauer, Stephanie Terezakis, Andrea Ferrari, Aaron R. Weiss, William H. Meyer, David O. Walterhouse, Timothy B. Lautz

“…We therefore to analyze the rate of N1 at diagnosis, the pattern of nodal relapse, and the prognostic impact of N1 in pediatric patients with NRSTS. …”
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Breeding of a new mid-to-late ripening apple cultivar Wangyuebingcui by XU Haihong, YANG Kai, LI Guangjin, ZHANG Guoqiang, TIAN Ge, AI Bohao, LI Xuqiang, WANG Junya

“…The cultivar combines high budbreak rate with moderate branching capacity, exhibiting spur-type growth pattern, sustained cluster-base productivity, and axillary flowering propensity. …”
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Low-level atmospheric turbulence dataset in China generated by combining radar wind profiler and radiosonde observations by D. Meng, D. Meng, J. Guo, J. Guo, J. Chen, X. Guo, N. Li, Y. Sun, Z. Zhang, Z. Zhang, N. Tang, H. Xu, T. Chen, R. Yang, J. Hua

“…This dataset includes squared Brunt–Väisälä frequency (<span class="inline-formula"><i>N</i>²</span>), turbulent dissipation rate (<span class="inline-formula"><i>ε</i></span>), vertical eddy diffusivity (<span class="inline-formula"><i>K</i></span>), inner scale (<span class="inline-formula"><i>l</i>₀</span>), and buoyancy length scale (<span class="inline-formula"><i>L</i>_B</span>), which are provided twice daily at 00:00 and 12:00 UTC with a vertical resolution of 120 m, covering altitudes from 0.12 to 3.0 km above ground level (a.g.l.). …”
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