Immunodiagnostic plasma amino acid residue biomarkers detect cancer early and predict treatment response by Cong Tang, Patrícia Corredeira, Sandra Casimiro, Qi Shi, Qiwei Han, Wesley Sukdao, Ana Cavaco, Cecília Melo-Alvim, Carolina Ochôa Matos, Catarina Abreu, Steven Walsh, Gonçalo Nogueira-Costa, Leonor Ribeiro, Rita Sousa, Ana Lorena Barradas, João Eurico Fonseca, Luís Costa, Emma V. Yates, Gonçalo J. L. Bernardes

“…By measuring the total concentrations of cysteine, free cysteine, lysine, tryptophan, and tyrosine protein-incorporated biomarkers and analyzing the results with supervised machine learning, we identify 78% of cancers with 0% false positive rate (N = 97) with an AUROC of 0.95. The cancer, healthy, and autoimmune/infectious biomarker pattern are statistically significantly different (p < 0.0001). …”
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Prognostic significance of acute exacerbations and usual interstitial pneumonia in fibrotic interstitial lung disease by Yun Zhang, Zekai Cen, Qunli Ding, Yanan Ying, Chengna Lv, Tingting Wu

“…The Kaplan‒Meier survival analysis showed that the IPF group (HR 1.97, 95% CI 1.05–3.70, P = 0.011) had a worse survival rate than the FILD group, and landmark analyses showed that the survival of FILD patients with the UIP pattern (HR 3.07 95% CI 1.37–6.86 P = 0.006) was significantly shorter than that of FILD patients with the NSIP pattern 48 months after ILD diagnosis. …”
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RNAi-mediated suppression of toll-like receptor NlToll1 enhances Nilaparvata lugens susceptibility to entomopathogenic fungal infection by Zhu-Long Shao, Chen-Ping Lan, Xiao-Ping Yu, Zheng-Liang Wang

“…Toll-like receptors (TLRs) are a family of crucial pattern recognition proteins that are responsible for the immunologic recognition of invading pathogen in insects. …”
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Three-dimensional cell sheet model improves in vitro prediction accuracy of osteogenic potential for biodegradable magnesium-based metals by Liangwei Chen, Guanxi Wu, Siyu Liu, Ziyu Yan, Honglei Yue, Jianhua Zhu, Na Ge, Yifei Wang, Qingxiang Li, Guanqi Liu, Tingting Zhang, Haowen Zheng, Shaozhe Xin, Guangyunhao Sun, Chuanbin Guo, Jianmin Han

“…Flow cytometry showed higher Ki67 expression and lower ROS levels and apoptosis rate in cell sheets. ShRNA-mediated silencing of N-Cadherin in cell sheets significantly compromised their cytoprotective capacity against Mg metal-induced toxicity. …”
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Response of the Invasive Cyanobacterium <i>Raphidiopsis raciborskii</i> to Iron and Phosphorus Concentrations in the Habitat: Effects on Growth and Cellular Phosphorus Distribution by Wenting Shen, Han Yang, Gaibian Ding, Bo Li, Xin Gan, Zijie Yuan, Liqing Wang, Wei Zhang

“…The results revealed that under conditions of sufficient inorganic phosphorus, there was a logarithmic relationship between ferric ammonium citrate (Fe³⁺) and the specific growth rate of <i>R. raciborskii</i>. Fe³⁺ > 2 mg/L enhanced IPS enrichment and biomass accumulation. …”
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Extreme Oncoplastic Surgery for Multifocal/Multicentric and Locally Advanced Breast Cancer by Chaitanyanand B. Koppiker, Aijaz Ul Noor, Santosh Dixit, Laleh Busheri, Gautam Sharan, Upendra Dhar, Hari Kiran Allampati, Smeeta Nare

“…EO followed by RT results in acceptable local-regional control, low rate of complications, and high patient satisfaction. …”
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Predictive value of D-Dimer and thromboplastin time as coagulation indicators for COVID-19 patients by Marwan Alshipli, Thamer A Altaim, Ammar A Oglat, Samira Ahmed Alsenany, Osama Khodrog, Hanan Hasan, Sally Mohammed Farghaly Abdelaliem, A Matrieh, Bassam Z Shakhreet, Riziq Allah Gaowgzeh

“…Within the two groups of patients, the rate of coagulation disorders was as follows: mild = 8.8 % within coagulation disorders, 4.8% within the two Groups; severe = 91.2 % within coagulation disorders, 77.8 % within the two Groups. …”
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Exciton-phonon coupling and phonon-assisted exciton relaxation dynamics in In1-xGaxP quantum dots by Beiye C. Li, Kailai Lin, Ping-Jui E. Wu, Aritrajit Gupta, Kaiyue Peng, Siddhartha Sohoni, Justin C. Ondry, Zirui Zhou, Caitlin C. Bellora, Young Jay Ryu, Stella Chariton, David J. Gosztola, Vitali B. Prakapenka, Richard D. Schaller, Dmitri V. Talapin, Eran Rabani, Gregory S. Engel

“…We identify a slower hot exciton cooling rate in In0.62Ga0.38P/ZnS, attributed to the presence of ‘energy-retaining’ valley exciton states with strong exciton-phonon coupling. …”
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Paradigm shift of respiratory viruses causing lower respiratory tract infection in children during COVID-19 pandemic in India by Mannat Kang, Subhabrata Sarkar, Suresh Kumar Angurana, Pankaj Singh, Meenakshi Rana, Ishani Bora, Rishi Chetanya, Bharatendu Singh, Jayashree Muralidharan, Radha Kanta Ratho

“…No significant difference in positivity rate of Inf A pdmH1N1, Inf A H3N2 and Inf B was seen. …”
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Prediction of Key Quality Parameters in Hot Air-Dried Jujubes Based on Hyperspectral Imaging by Quancheng Liu, Chunzhan Yu, Yuxuan Ma, Hongwei Zhang, Lei Yan, Shuxiang Fan

“…To further enhance modeling accuracy, deep learning models such as bidirectional long short-term memory (BiLSTM), bidirectional gated recurrent unit (BiGRU), and convolutional neural network–bidirectional gated recurrent unit (CNN-BiGRU) were introduced and compared comprehensively under the optimal spectral preprocessing conditions. …”
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Fosfomycin susceptibility in multidrug resistant uropathogens: A retrospective study in the era of antimicrobial resistance by Jasleen Kaur, Priya Bhat, Upasana Bhumbla

“…Background: Urinary tract Infection is one of the most prevalent clinical entities affecting people worldwide. The accelerating rate of antimicrobial resistance due to the unimpeded and rampant use of antimicrobials with over the counter availability of drugs has limited the therapeutic options for the treatment of UTI. …”
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Salmonella spp. Inactivation During Hot Air Drying of Apples: Influence of Temperature, Bed Depth, and Air Velocity by Xiyang Liu, Elizabeth M. Grasso-Kelley, Alvin Lee, Lilybell Warda, Nathan M. Anderson

“…Increased air velocity shortened the constant-rate drying period, promoted a faster temperature increase in the apple cubes, and resulted in higher lethality within a shorter drying period. …”
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The Effects of a Small Dose of Tannin Supplementation on In Vitro Fermentation Characteristics of Different Forages by Sytske de Jong, Fabiellen C. Pereira, Alejandro R. Castillo, Wilbert F. Pellikaan, Pablo Gregorini

“…The addition of tannins reduced the fractional rate of gas production for alfalfa (<i>p</i> ≤ 0.04) but increased it for ryegrass and plantain. …”
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Efficiency of foliar application with organic fertilizer agrochelate on seed plots of summer sowing watermelon by O. V. Yakimova, V. E. Lazko, E. N. Blagorodova

“…Organic fertilizer AGROCHELATE was used to treat the leaf surface of plants with a consumption rate of 100 ml/ha. A single spraying was used during the flowering phase of the plants. …”
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Transcutaneous bilirubin nomogram for Taiwanese newborns – A single center study by Tung-Hua Chen, Yung-Chieh Lin, Yuh-Jyh Lin, Chyi-Her Lin

“…Mean TCB levels increased at a rate of 0.01–0.21 mg/dL/h initially, followed by a decrease after 96–108 h of age. …”
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Subnational malaria burden in Sindh, Pakistan: over a decade of evidence for tailored strategies by Nelofer Baig, Zakir Ali, Muhammad Ahmed, Wafa Zehra Jamal, Saqib Ur Rehman, Zafar Ahmed, Riaz Hussain Rahoojo, Javed Ali Jagirani, Bilal Ahmed Usmani, Zafar Fatmi

“…Marked heterogeneity observed in malaria burden across districts. Malaria positivity rate was 12.3%. Six districts (Khairpur, Sanghar, Naushero Feroze, Badin, Mirpurkhas, and Larkana) carried over 53% burden of malaria in Sindh. …”
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Tetrahymena ATG8 homologs, TtATG8A and TtATG8B, are responsible for mitochondrial degradation induced by starvation by Shinya Matsuda, Chieko Saito, Mami Nomura, Hitomi Kawahara, Noboru Mizushima, Kentaro Nakano

“…The ciliate Tetrahymena exhibits active swimming behavior in water, preying on microorganisms and growing exponentially at a rate of 0.5–0.75 h⁻¹ under optimal conditions. In this organism, numerous mitochondria localize to the cell cortex along the ciliary rows, likely ensuring an efficient ATP supply necessary for vigorous cell movement. …”
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Clinical Efficacy and Safety of the Herbal Prescription, HH333, in Preventing Recurrent Stroke in Patients With Ischemic Stroke Induced by Small-Vessel Disease: Protocol for Multic... by Han-Gyul Lee, Seungwon Kwon, Woo-Sang Jung, Sang-Kwan Moon, Cheol-Hyun Kim, Dong-Jun Choi

“…Efficacy will be assessed using the recurrence rate of ischemic stroke, which will be assessed on days 30, 90, 180, 270, 360, 450, 540, 630, 720, and 750 after starting the medication. …”
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An Epidemiological Review of the Impact of COVID-19 on Achilles Tendon Rupture Injuries, Experience from a Large London District General Hospital by Lena Al-Hilfi, Irrum Afzal, Sarkhell Radha, Mohamed Abdalla, Mohammed Al-Maiyah

“…As lockdown measures began to ease, hospitals experienced a high admission rate of patients presenting with Achilles Tendon Rupture [ATR]. …”
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The Role of Intestinal Translocation in the Pathogenesis of Pneumonia in Acute Poisoning and the Contribution of Intestinal Lavage to Its Prevention and Resolution by V. A. Matkevich, T. T. Tkeshelashvili, A. G. Vorobyova, N. E. Stolbova, M. M. Potskhveriya, Yu. S. Goldfarb

“…Mortality among the patients with PPD poisoning decreased by 7 times, and with M and CS poisoning, as well as with AlD, there were no deaths, while in the respective comparison groups, the mortality rate for pneumonia was 5.1, 7.4, and 17.4 %, respectively. …”
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