Single-cell RNA sequencing technology was employed to construct a risk prediction model for genes associated with pyroptosis and ferroptosis in lung adenocarcinoma by Longfei Ji, Binyu Wang, Danfei Shi, Weiyun Shen, Xinmin Li, Yong Li

“…Abstract Background Lung adenocarcinoma (LUAD) is one of the most common subtypes of non-small cell lung cancer, and its mortality rate remains high. As a programmed cell death mode closely related to inflammation, pyroptosis has been found to play an important regulatory role in the tumor immune microenvironment and tumor progression in recent years. …”
Get full text

Single-cell RNA sequencing reveals immunological link between house dust mite allergy and childhood asthma by Lingyun Zou, Kang Chen, Xianou Hong, Bo Ye

“…Nevertheless, the diagnostic rate remains below 60% due to the absence of specific symptoms and diagnostic markers, which hinders the implementation of targeted personalized therapies. …”
Get full text

Profile of the geriatric patient hospitalised at Universitas Hospital, South Africa by Anna M. van Staden, Dirk J.V. Weich

“…Women represented 66% of the patients and the mortality rate was 17% in the total study group. The main admitting clinical problems were hypertension, heart failure, ischemic heart disease and anaemia. …”
Get full text

Metode Deteksi Intrusi Menggunakan Algoritme Extreme Learning Machine dengan Correlation-based Feature Selection by Sulandri Sulandri, Achmad Basuki, Fitra Abdurrachman Bachtiar

“…The results of the research conducted using the ELM method showed an accuracy rate of 81.97% with a computation time of 3.39 seconds. …”
Get full text

Towards more reliable gambling cost estimates, a population-based study with register-linkage by Tiina A. Latvala, Matthew Rockloff, Matthew Browne, Tomi Roukka, Tomi P. Lintonen, Anne H. Salonen

“…Additionally, costs could be presented as Int$ per adult using the PPP exchange rate to facilitate the comparison of gambling costs between countries.…”
Get full text

Non-linear association between neutrophil-to-lymphocyte ratio and 90-day mortality in patients with pneumonia receiving glucocorticoids alone or in combination with other immunosup... by Caizhen Chen, Xiuguo Zhang, Baoli Li, Qian Geng

“…There were 332 individuals (47.7%) aged 18-59 years and 364 (52.3%) aged 60-99 years; 52.6% were male. The 90-day mortality rate across the study population was 26.1%. A non-linear association was noted between NLR and 90-day mortality, with an inflection point at approximately 16.475. …”
Get full text

Observational Study on Progressive Muscle Relaxation and Breathing Control for Reducing Dental Anxiety in Children by Sorana Maria Bucur, Ioana Maria Crișan, Dorin Ioan Cocoș, Eugen Silviu Bud, Carmen Galea

“…Dental anxiety was measured with the Romanian-validated IDAF-4C⁺, and physiological stress was measured via blood pressure and heart rate. Pre and post-intervention data were analyzed using paired <i>t</i>-tests, ANOVA, and cluster analysis. …”
Get full text

A biobank for complex post-traumatic stress disorder (C-PTSD) and PTSD: study protocol for a cross-sectional study by Alice Mok, Chrystal Douflias, Lena K. L. Oestreich

“…Additionally, participants will wear an Actigraph smart watch for seven days to collect actigraphy-derived physiological data, including sleep patterns and heart rate variability. All de-identified data will be made openly available on the Open Science Framework upon publication of the main study findings, in accordance with ethical approvals and institutional guidelines for privacy and data security.Conclusion This comprehensive protocol addresses significant gaps in understanding C-PTSD through its multimodal approach. …”
Get full text

Long-term clinical sequelae in severe fever with thrombocytopenia syndrome: A longitudinal cohort study. by Ning Cui, Xin Yang, Hong-Han Ge, Xiao-Hong Yin, Yi-Mei Yuan, Chao Zhou, Xi Wang, Hai-Feng Pan, Hao Li, Xiao-Ai Zhang, Li-Qun Fang, Li-Fen Hu, Peng-Tao Bao, Wei Liu

“…<h4>Background</h4>Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne infectious disease characterized by a high case fatality rate. Despite extensive research on acute-phase manifestations, the long-term clinical sequelae in survivors remain poorly characterized.…”
Get full text

Monitoring of urinary microbiota and uropathogens' antibiotic resistance in one urological hospital by Yu. L. Naboka, A. K. Alkina, M. I. Kogan, I. A. Gudima, Kh. S. Ibishev, K. T. Jalagoniya, M. L. Chernitskaya

“…The detection frequencies of E. coli vary around 50.0%, for other causative pathogens a lower detection rate is noted, while non-clostridial anaerobic bacteria are excreted in 96.6% of cases in patients with recurrent uLUTI. …”
Get full text

Adapting Vision Transformer-Based Object Detection Model for Handwritten Text Line Segmentation Task by Osman Furkan KARAKUŞ, Ayla GULCU, Ali Can KARACA

“…Experimental results based on the Intersection over Union (IoU) metric demonstrate that the proposed method outperforms all other methods in terms of the detection rate, recognition accuracy, and Text Line Detection Metric (TLDM). …”
Get full text

Model characteristics of the structure and interrelations of integral parameters of students' physical condition by Oleksandr Pryimakov, Marek Sawczuk, Oleksii Tymoshenko, Nataliya Mazurok

“…A strong relationship between APWC and resting heart rate (HR) was identified during testing, with boys demonstrating higher levels of APWC at lower initial HR values compared to girls. …”
Get full text

Surgical management and outcomes of corrosive esophageal injuries: a prospective study from Sana’a, Yemen by Mohammed Mohammed Al-Shehari, Yasser Abdurabo Obadiel, Ahmed Hamood Al-Helali, Haitham Mohammed Jowah

“…The elevated mortality rate among suicidal cases highlights the need for mental health support. …”
Get full text

Competition and temperature could drive radial growth of Schima superba in humid subtropical forests of China by Ziru Niu, Shaowei Jiang, Juan Li

“…The Chinese subtropical evergreen broadleaved forest, a region with a high net carbon sink rate, is currently experiencing climatic warming and changes in precipitation patterns that may increase aridity and alter stand structure. …”
Get full text

Association between self-reported sleep quality and body mass index among Jimma University academic staff: structural equation modeling by Essa Ahmed, Getu Gizaw, Alemayehu Argaw

“…That year, around 16% of adults aged 18 and above were classified as obese. The global obesity rate more than doubled from 1990 to 2022. By 2035, the World Obesity Atlas predicts that over 1 billion people worldwide will be considered obese, which translates into 1 in 5 women and 1 in 7 men will be affected globally. …”
Get full text

Pengujian Rule-Based pada Dataset Log Server Menggunakan Support Vector Machine Berbasis Linear Discriminat Analysis untuk Deteksi Malicious Activity by Kurnia Adi Cahyanto, Muhammad Anis Al Hilmi, Muhamad Mustamiin

“…From the modeling, the results show that the LDA-based SVM algorithm has a training accuracy rate of 90,2% and testing 89,9% in performing rule-based testing for activity labeling on the web server.   …”
Get full text

Contrast-enhanced ultrasound and elastography predict histopathology and recovery in acute kidney injury by Xiangyu Wang, Jiajia Liu, Luzeng Chen, Tao Su

“…We aim to explore the potential correlation of CEUS–SWE derived parameters (peak intensity (PI), rise time (RT), time to peak (TTP), and shear wave velocity (SWV)) with renal histopathology and 3-month outcomes (renal recovery: estimated glomerular filtration rate (eGFR) ≥45 mL/min/1.73 m2).Results CEUS revealed stage-specific perfusion patterns: milder AKI (eGFR >25 mL/min/1.73 m2) showed medullary hyperemia (cortical-to-medullary PI ratio: 0.80 ± 0.24 vs. 1.12 ± 0.18 in controls; p < .05), a potential compensatory response to medullary hypoxia. …”
Get full text

Spatial Change of Dominant Baltic Sea Demersal Fish Across Two Decades by Liam MacNeil, Frane Madiraca, Saskia Otto, Marco Scotti

“…Local densities drive differences in species contributions to ecological processes and ecosystem function rather than through presence alone. If a species growth rate is strongly controlled by macro‐environmental conditions, then predicting geographical abundance or densities should be possible. …”
Get full text

Characterizing pediatric dermatological presentations in an outer metropolitan emergency department: a single-center Western Australian study by Tristen Tze Wei Ng, Darren Zhi-Yang Low, Amelia Ye Chiung Tang, Mabel Zhi Qi Foo, Dale Wesley Edgar, Paul Anthony Hill

“…Results Of the 540 pediatric patients who presented to the ED with a dermatological complaint, 44.4% were girls with a median age of 4.5 years (interquartile range, 1.5-9.3) and a hospitalization rate of 7.6%. The dermatologic diagnoses consisted of AUD (34.3%), infective dermatoses (29.3%), EOD (23.3%), AAE (8.5%), and not elsewhere classified (4.6%). …”
Get full text

Network-based intrusion detection using deep learning technique by Muhammad Farhan, Hafiz Waheed ud din, Saadat Ullah, Muhammad Sajjad Hussain, Muhammad Amir Khan, Tehseen Mazhar, Umar Farooq Khattak, Ines Hilali Jaghdam

“…Abstract A high growth rate in network traffic and the complexity of cyber threats have made it necessary to create more effective and flexible intrusion detection systems. …”
Get full text