Revisiting biomarker discovery by plasma proteomics by Philipp E Geyer, Lesca M Holdt, Daniel Teupser, Matthias Mann

“…However, existing biomarkers are far from comprehensive and often lack specificity and new ones are being developed at a very slow rate. As described in this review, mass spectrometry (MS)‐based proteomics has become a powerful technology in biological research and it is now poised to allow the characterization of the plasma proteome in great depth. …”
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Estimating the Impact of Technical Barriers to Trade in WTO Regime: The Case of Pakistan by Amir Mustafa, Ihtsham Ul Haq Padda, Sadia Safdar

“…The findings depict that GDP of Pakistan and partners, exchange rate, tariff, distance, and contiguity are vital factors; along with TBT cases initiated by Pakistan have also impacted import from WTO members. …”
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NEW POSSIBILITIES OF RADIOLOGIC DIAGNOSTICS OF BREAST CANCER by A. B. Abduraimov, S. K. Ternovoy

“…Early breast cancer diagnosis is contemporary and actual problem due to the increase of breast cancer incidence and low detection rate of the disease.Multispiral computed tomography of mammary gland with intravenous contrast agent injection allows resolving diagnostic tasks aris- ing in patients with high density mammary gland tissue, considerable edema, fibrosis, postoperative conditions. …”
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LEFT VENTRICULAR WALL THICKNESS AND AUTONOMIC REGULATION IN PATIENTS WITH HYPERTROPHIC CARDIOMYOPATHY by O. Allaberganov, T. A. Abdullaev, G. A. Nagaeva

“…In addition, Group II patients demonstrated autonomic disbalance, sympathetic hyperactivity, and disturbed circadian patterns of heart rate.…”
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The Convallis rule for unsupervised learning in cortical networks. by Pierre Yger, Kenneth D Harris

“…Implementation of the rule caused a recurrent cortex-like network of simulated spiking neurons to develop rate representations of real-world speech stimuli, enabling classification by a downstream linear decoder. …”
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Altruism Enhances Frontal Alpha Asymmetry and Reduces Sympathetic Activity: A Multimodal EEG‐ECG Study With Implications for Therapeutic Interventions by Junya Orui, Keigo Shiraiwa, Takao Inoue, Masaya Ueda, Keita Ueno, Yasuo Naito, Ryouhei Ishii

“…Parasympathetic activity negatively correlated with temporal‐gamma connectivity (p = 0.002), and heart rate change negatively correlated with temporal‐prefrontal theta connectivity (p = 0.048). …”
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Spatial disparities of population aging in Shenzhen: from China’s Hukou perspective by Qing Luo, Zhuoying Li, Yuanjun Li, Yunhao Yang, Jiaxin Liu, Guangbo Liu, Huayi Wu

“…Although its overall aging rate remains below the international aging society threshold, the city confronts unique challenges as a migrant receiving metropolis without domestic precedents. …”
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Analysis of complex chromosomal structural variants through optical genome mapping integrated with karyotyping by Xiaoxi Zhu, Huiling Zheng, Xue Wan, Hang Duan, Ying Qi, Weijia Tang, Fan Yang, Fan Yang, Limei Yu, Limei Yu

“…This advancement substantially enhances the diagnostic rates of genetic etiology in patients experiencing RSA. …”
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Differences in geochemical characteristics of produced water from coalbed methane wells and their indications for drainage：A case study of the Santang Syncline in Western Guizhou by Xiaozhi ZHOU, Shuaiqi WANG, Shiliang ZHU, Shaolei WANG, Gang XIANG, Xuehua CHEN, Jihang DONG, Xin QIU

“…Combined with the monitoring of the water quality and hydrochemical characteristics of the produced water from CBM wells, the overflow release process after fracturing is divided into four stages: trial flowback, constant-rate flowback, slow increase of the flowback rate, and rapid decrease of the flowback rate. …”
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Burden and Outcomes of Severe Lower Respiratory Tract Infections with Unknown Etiology: A Retrospective Observational Study on Epidemiological Trends Over an 8-Year Period (2016–20... by Giovanni Scaglione, Marta Canuti, Martina Offer, Valentina Breschi, Antonio Piralla, Fausto Baldanti, Gabriele Del Castillo, Francesco Scovenna, Sabrina Buoro, Federica Morani, Danilo Cereda, Alessandra Bandera, Andrea Gori, Marta Colaneri

“…Results Among 683,741 hospitalizations, 338,211 (49.5%) were of unknown etiology, showing a 12.3% intra-hospital mortality rate (41,627 deaths) and 4.0% intensive care unit admission rate (13,625 admissions). …”
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Radiocleavable rare-earth nanoactivators targeting over-expressed folate receptors induce mitochondrial dysfunction and remodel immune suppressive microenvironment in pancreatic ca... by Tanvi Gupta, Shang-Rung Wu, Li-Chan Chang, Forn-Chia Lin, Yan-Shen Shan, Chen-Sheng Yeh, Wen-Pin Su

“…Abstract Pancreatic cancer is a fatal cancer with poor prognosis and survival rate, often diagnosed usually in the advanced stage of disease. …”
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Machine learning and microfluidic integration for oocyte quality prediction by Hassan Saffari, Davood Fathi, Peyman Palay, Hamid Gourabi, Rouhollah Fathi

“…Additionally, oocyte diameter and the critical flow rate (Q)—defined as the minimum flow rate necessary for an oocyte to pass through the channel—were included as predictive variables. …”
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Impact of Sodium Ion Stress on the Mechanism of Lead Ion Migration in Electrochemical Treatment of Lead-Contaminated Soil by Yinyin Zhang, Jiangtao Han, Libin Zang

“…This study specifically validates the migration patterns of lead ions under sodium ion stress in soil and concludes that a high concentration of sodium ions, when coexisting with lead ions, diminishes the migration rate of lead ions, consequently reducing the removal efficiency of lead ions. 1. …”
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Identification and Validation of the lncRNA BACE1-AS as Immune-Related Influencing Factor in Tumorigenesis following Pan-Carcinoma Analysis by Mengmeng Wang, Di Chen, Yushuang Xu, Mengjun Qiu, Xin Jiang, Zhifan Xiong

“…Overall, our results suggest that BACE1-AS is associated with the expression, prognosis, and rate of immune cell infiltration of most tumors. …”
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Spatial proximity effects on cognitive processing of multimedia learning among college students: evidence from functional near-infrared spectroscopy by Yan Ma, Yan Ma, Qiuyue Peng, Qiuyue Peng, Bowen Long, Bowen Long

“…In addition, the study also explored how disciplinary differences affect the strength of spatial proximity effects and corresponding brain activation patterns.ResultsThe findings revealed that activation levels in the middle temporal gyrus, frontal pole, and dorsolateral prefrontal cortex were significantly higher in the spatial proximity condition compared to the spatial separation condition, accompanied by an improved rate of correct answers. …”
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The 'Antiretrovirals, Sexual Transmission Risk and Attitudes' (ASTRA) study. Design, methods and participant characteristics. by Andrew Speakman, Alison Rodger, Andrew N Phillips, Richard Gilson, Margaret Johnson, Martin Fisher, Ed Wilkins, Jane Anderson, Rebecca O'Connell, Monica Lascar, Kazeem Aderogba, Simon Edwards, Jeffrey McDonnell, Nicky Perry, Lorraine Sherr, Simon Collins, Graham Hart, Anne M Johnson, Alec Miners, Jonathan Elford, Anna-Maria Geretti, William J Burman, Fiona C Lampe

“…In this paper we describe the study rationale, design, methods, response rate and the demographic characteristics of the participants. …”
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Adaptive AI-enhanced computation offloading with machine learning for QoE optimization and energy-efficient mobile edge systems by Dinesh Kumar Nishad, Vandna Rani Verma, Pushkar Rajput, Sandeep Gupta, Anurag Dwivedi, Dharti Raj Shah

“…The system’s security analysis yields a 98% threat detection rate, with response times under 100 ms. Meanwhile, reliability metrics indicate a 99.8% task completion rate and a mean time to failure of 1,200 h. …”
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The Role of Intrinsic Factors in Explaining Range Shifts of European Breeding Birds: A Meta‐Analysis by Femke E. M. Warmer, Wessel A. vanVliet, Pim vanHooft, Anouschka R. Hof

“…However, the observed range shift patterns are idiosyncratic in rate and direction. Species traits, such as ecological, life‐history and movement traits, may play an important role in determining range shifts by influencing a species' capacity to shift successfully. …”
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Rehabilitation and Motion Symmetry Analysis With a TACX Smart Cycling Trainer Using Computational Intelligence by Hana Charvatova, Daniel Martynek, Alexandra Molcanova, Ales Prochazka

“…The research objectives include analysis of motion patterns, evaluation of motion symmetry under varying loads, and examination of heart rate responses to load variations. …”
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Prediction of Salinity Based on Meteorological Data Using the Backpropagation Neural Network Method by Anisa Nur Azizah, Dian C.R. Novitasari, Putroue Keumala Intan, Fajar Setiawan, Ghaluh Indah Permata Sari

“…This study conducted several backpropagation architectural experiments, that is the learning rate, hidden layer, and the number of nodes in the hidden layer to obtain the best results. …”
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