Multi-omics derivation of a core gene signature for predicting therapeutic response and characterizing immune dysregulation in inflammatory bowel disease by Mingming Wang, Liping Liang, Zibo Tang, Jimin Han, Lele Wu, Le Liu, Le Liu, Ye Chen, Ye Chen

“…Nomogram-based risk stratification effectively predicted biologic treatment responses across multiple therapeutic classes using four independent treatment datasets (GSE16879, GSE92415, GSE73661, GSE206285): low-risk patients demonstrated superior response rates to golimumab (63.3%), infliximab (54.8%), and vedolizumab (29% vs. 15% in high-risk group). …”
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Outpatient Testing for HIV in Italy, 2018–2023—Preliminary Data by Claudio Galli, Vincenza Regine, Anna Caraglia, Francesca Centrone, Maria Chironna, Gianluca Cruschelli, Massimo Farinella, Valentina Annachiara Orlando, Chiara Pasqualini, Monia Puglia, Lucia Pugliese, Laura Rancilio, Lara Tavoschi, Fabio Voller, Barbara Suligoi

“…We started a research project aimed at assessing testing rates for HIV infection among Italian outpatients in 2018–2023. …”
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Eruptive modes and hiatus of volcanism at West Mata seamount, NE Lau basin: 1996–2012 by Robert W. Embley, Susan G. Merle, Edward T. Baker, Kenna H. Rubin, John E. Lupton, Joseph A. Resing, Robert P. Dziak, Marvin D. Lilley, William W. Chadwick Jr., T. Shank, Ron Greene, Sharon L. Walker, Joseph Haxel, Eric Olson, Tamara Baumberger

“…Based on the historical eruption rates calculated using the bathymetric differencing technique, the volcano could be as young as several thousand years.…”
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Short light/dark cycles favour photosynthetic efficiency and growth in grapevines by Mariana Gómez Tournier, Laurent Torregrosa, Jana Kändler, Angélique Christophe, Romain Boulord, Anna Medici, Anne Pellegrino

“…T3/3 in both genotypes maintained stable net photosynthetic rates (An) and high photosystem II efficiency (φPSII) during the light cycle, avoiding the 62 % drop observed under T12/12 after 3 h of exposure. …”
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Comparing survival outcomes of anti-fibrotic therapy for idiopathic pulmonary fibrosis with and without emphysema: a multi-center real-world study from Taiwan by Yu-Hung Fang, Yi-An Hsieh, Yen-Fu Chen, Yu-Chi Chiu, Yu-Ching Lin, Kuo-Tung Huang, Yung-Chia Huang, Yu-Feng Wei, Chien-Wen Huang, Pin-Kuei Fu, Taiwan Multi-Centre Interstitial Lung Disease Research Consortium

“…During a median follow-up of 3.7 years, the overall survival rates were comparable (IPF only: 45.6%; IPF with emphysema: 48.4%). …”
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Stem introducer designs and surgical technique play a significant role in achieving the optimal implant-cement interface by Bernard H. van Duren, Kevin Ilo, Sophie Walker, Mark Higgins, Benjamin V. Bloch, Andrew R. Manktelow, Hemant G. Pandit

“…A significant variation exists between PTS stem designs, associated fractured rates among them, and the design of introducers used. …”
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Path to full immunisation coverage, role of each vaccine and their importance in the immunisation programme: a cross-sectional analytical study of India by Gunjan Taneja, Pawan Kumar, Disha Agarwal, Ajay Kumar Verma, Pritu Dhalaria, Sanjay Kapur, Ajeet Kumar Singh, Bhupendra Tripathi

“…The prevalence of absolute zero-dose children, antigen-wise zero dose, co-coverage rates and cascade levels for vaccine combinations are assessed. …”
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Impact of oral hygiene on the development of oropharyngeal neoplasms by D. G. Kiparisova, Yu. S. Kiparisov, N. S. Nurieva

“…The patient hygiene performance (PHP) index (Podshadley, Haley, 1968) was used to estimate his/her baseline ability. The rates of initial visits made by patients with oropharyngeal tumors to physicians of different specialties were also analyzed.Results. …”
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Meningitis caused by Aspergillus fumigatus: a case report by Yifei Zhang, Yu Ma, Rushuang Yue, Yuan Meng, Yue Jin, Chengwei Yin, Qianmei Zhou, Rong Shi

“…Conclusion A. fumigatus meningitis represents a rare but life-threatening infection characterized by diagnostic challenges and alarmingly high mortality rates. Stringent diagnostic vigilance is essential to avoid diagnostic errors in these cases. …”
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Comparison of phytochemical composition, antimicrobial, antifungal, and antioxidant activities of lipophilic and ethanolic green tea leaf extracts by O. Yu. Maslov, M. A. Komisarenko, S. V. Ponomarenko, S. V. Kolisnyk, T. P. Osolodchenko, M. Yu. Golik

“…The lipophilic extract exhibits greater inhibition of the growth of S. aureus, E. coli, P. vulgaris, B. subtilis, and C. albicans compared to the 96 % ethanolic extract processed with chloroform, with inhibition rates of 19 %, 18 %, 12 %, 12 %, 16 %, and 20 % respectively. …”
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SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK: NEW AVENUES OF TREATMENT? by T. Braunschweig, A. Lewandrowski, D. Smeets, M. V. Bolotin

“…HPV related squamous cell carcinomas show better survival data, especially in regard to recurrence free rates or secondary carcinoma of adjacent locations. …”
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Clinical, epidemiological, and virological features of Mpox in Beijing, China – May 31–June 21, 2023 by Xiangfeng Dou, Fu Li, Zhenyong Ren, Daitao Zhang, Jia Li, Dan Li, Yulan Sun, Haoyuan Jin, Renqing Li, Weihong Li, Xin Zhang, Yang Yang, Lei Jia, Yu Han, Wai Li, Yang Pan, Wenjie Tan, Peng Yang, Quanyi Wang

“…There were high oropharyngeal swab (75.8%) and blood (84.6%) positivity rates. All MPXV strains belonged to the B.1.3 branch of the West African lineage. …”
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A low-cost mitigation system for ammonia removal from broiler house exhaust air by Jingjing Luo, Jinsheng Rong, Shizhen Zhou, Haoliang Wang, Miao Li, Xiliang Yan, Yingbao Wu, Yan Wang

“…The results of the environmental simulation chamber show that 80 ppm hypochlorous acid and 70 ppm chlorine dioxide are cost-effective, achieving high ammonia (NH₃) removal rates. Field validation in a broiler house demonstrated that using 80 ppm hypochlorous acid with the ARBS achieved NH₃ and dust removal efficiencies of 82 % and 77 %, respectively. …”
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Gut Microbiota and Lipid Metabolism in Bullfrog Tadpoles: A Comparative Study Across Nutritional Stages by Zhilong Wang, Pengxiang Liu, Jun Xie, Huirong Yang, Guangjun Wang, Kai Zhang, Rui Shu, Zhifei Li, Jingjing Tian, Hongyan Li, Wenping Xie, Wangbao Gong, Yun Xia

“…These insights provide a theoretical foundation for nutritional interventions aimed at enhancing tadpole growth and survival rates.…”
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Bridging micro and macroevolution: insights from chromosomal dynamics in plants by Carmen Benítez-Benítez, Ashwini V. Mohan, Rogelio Sánchez-Villegas, Inés Gómez-Ramos, Ana Valdés-Florido, Kay Lucek, Marek Slovák, Marek Slovák, Filip Kolář, Filip Kolář, Ilia J. Leitch, Modesto Luceño, Isabel Larridon, Angelino Carta, Angelino Carta, Joan Cuscó-Borràs, Enrique Maguilla, Alegría Montero-Ramírez, Patrick G. Meirmans, Alison Dawn Scott, Santiago Martín-Bravo, Marcial Escudero

“…At the macroevolutionary level, we investigated the association between karyotype diversity and diversification rates using evidence from comparative genomics, chromosomal evolution modelling across phylogenies, and the association with several traits across different angiosperm lineages. …”
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Characteristics of Anemia in Children Aged 6 Months to 5 Years Attending External Consultations at a Pediatric Hospital in Lisbon, Portugal by Réka Maulide Cane, Sérgio Chicumbe, Youssouf Keita, Anaxore Casimiro, Bárbara Martins Saraiva, Joana Vasconcelos, Beatriz Luzio Vaz, Afonso Sousa, Mafalda Cabral, Francisco Branco Caetano, Luís Varandas, Isabel Craveiro

“…Five children (6.8%) had normal hemoglobin but abnormal red-cell indices, with microcytic (60.0%; 3/5) or normocytic (40.0%; 2/5) patterns. Anemia rates were higher in males (55.1%), children aged 24–59 months, those residing in the Metropolitan Lisbon Area (82.6%), children whose caregivers had only basic or secondary education (58.0%), and those whose mothers were born in foreign countries (48.4%). …”
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Changing trends in oral mucosal diseases in China (2016–2024): a cross-sectional study of 316,166 patients with focus on COVID-19 impact and use of chinese patent medicines by Peiru Zhou, Xu Zhang, Yifan Chen, Jiakun Fang, Yanhong Meng, Furong Yang, Pan Wei, Hong Hua

“…Despite variations in prevalence rates of oral mucosal diseases across regions, previous studies often involved small sample sizes with insufficient data analysis. …”
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Comprehensive assessment of adverse event profiles associated with bispecific antibodies in multiple myeloma by Mobina Golmohammadi, Shahzad Raza, Maram Albayyadhi, Hossein Sholehrasa, Jack Khouri, Louis Williams, Doris K. Hansen, Azam Moradi, Xuan Xu, Moath Albliwi, Ali Hajj Ali, Danai Dima, Faiz Anwer, Barry Paul, Majid Jaberi-Douraki

“…GPRC5D/FcRH5 are associated with less grade 3/4 hematologic toxicity whereas BCMA BsAbs were associated with lower grade 3/4 CRS rates, compared to GPRC5D/FcRH5. These insights are crucial for guiding treatment decisions and developing strategies to improve patient outcomes.…”
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Effects of Live and Peptide-Based Antimicrobiota Vaccines on <i>Ixodes ricinus</i> Fitness, Microbiota, and Acquisition of Tick-Borne Pathogens by Apolline Maitre, Lourdes Mateos-Hernandez, Myriam Kratou, Natalia Egri, Jennifer Maye, Manel Juan, Adnan Hodžić, Dasiel Obregón, Lianet Abuin-Denis, Elianne Piloto-Sardinas, Andrea C. Fogaça, Alejandro Cabezas-Cruz

“…We monitored the tick feeding behavior, survival rates, and infection levels. Additionally, we employed comprehensive microbiota analyses, including the alpha and beta diversity assessments and microbial co-occurrence network construction. …”
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Effects of Regulated Deficit Irrigation on Leaf Nutrients, Enzyme Activities, and Root Zone Soil Nutrients during Fruit Expansion and Coloration-Sugar Accumulation Stages of Citrus... by ZHONG Yun, HUANG Zhikun, ZHU Shijiang, HAO Kun, ZHU Zirong, ZHANG Wei, CHEN Hongde

“…The aim was to explore the response patterns of soil nutrients, citrus leaf nutrients, antioxidant enzyme activities, and root-zone soil nutrients to water stress under drip irrigation across different growth stages. …”
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