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1661
Assessing Natural Variation as a Baseline for Biodiversity Monitoring: The Case of an East Mediterranean Canyon
Published 2025-03-01“…Despite substantial species turnover rates between periods in all the taxa, almost no change was found regarding the biogeographical origins of plant and beetle species composition. …”
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1662
Deep learning enhanced road traffic analysis: Scalable vehicle detection and velocity estimation using PlanetScope imagery
Published 2025-08-01“…Satellite-based approaches provide broad spatial coverage, but face challenges, including high costs, low frame rates, and difficulty detecting small vehicles in medium-resolution imagery. …”
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1663
Antitumor power of oncolytic HSV engineered with IL-12 and IL-15
Published 2025-09-01“…Treatment with RG2006 significantly reduced tumor growth and extended survival rates compared to other forms of oHSV-1. Analyses indicated a marked elevation in T cell and NK cell activation in mice receiving RG2006. …”
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1664
<i>SHROOM3</i> Deficiency Aggravates Adriamycin-Induced Nephropathy Accompanied by Focal Adhesion Disassembly and Stress Fiber Disorganization
Published 2025-06-01“…Clinically, the glomerular <i>SHROOM3</i> expression positively correlated with glomerular filtration rates in focal segmental glomerulosclerosis patients. …”
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1665
Satellite-Based Prediction of Water Turbidity Using Surface Reflectance and Field Spectral Data in a Dynamic Tropical Lake
Published 2025-07-01“…In this study, we utilized Landsat satellite imagery in conjunction with near-synchronous in situ reflectance measurements to monitor spatial and seasonal turbidity patterns between 2023 and 2025. The surface reflectance was radiometrically corrected and validated using spectroradiometer data collected across eight sampling sites in the eastern sector of the lake, the area where the highest rates of horizontal change in turbidity occur. …”
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1666
Nutritional status, body indices, and somatotype in Aymara and Quechua children from high Andean areas of Peru
Published 2025-01-01“…Among the findings, most children presented normal nutritional status according to BMI-for-age and height-for-age Z-scores. However, high rates of overweight and obesity were observed in Aymara (39%) and Quechua (28.4%) children, with differences in fat content between ethnic groups at the 5th, 10th, 50th, and 75th percentiles. …”
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1667
Mutation Profiling of Premalignant Colorectal Neoplasia
Published 2019-01-01“…HGD adenomas had significantly higher mutation rates than LGD adenomas, while LGD-H adenomas exhibited mutation frequencies similar to those of LGD adenomas. …”
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1668
Real-world effectiveness and safety of CDK4/6i in elderly and BIPOC patients with HR+/HER2- advanced/metastatic breast cancer: an updated systematic literature review
Published 2025-08-01“…Key outcomes for synthesis were effectiveness, treatment patterns, and safety.ResultsThis review included 23 unique studies. …”
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1669
Improvement of Oral Anticoagulant Prescription and Long‐Term Clinical Outcomes of Patients With Atrial Fibrillation After Implementation of a Clinical Decision Support System in Ou...
Published 2025-08-01“…Results OAC prescription rates increased from 47.3% to 67.5% after CDSS implementation. …”
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1670
Exploring mobility data for enhancing HIV care engagement in Black/African American and Hispanic/Latinx individuals: a longitudinal observational study protocol
Published 2023-12-01“…Mobility data that measure individuals’ movements over time in combination with sociostructural data (eg, crime, census) can potentially identify barriers and facilitators to HIV care engagement and can enhance public health surveillance and inform interventions.Methods and analysis The proposed work is a longitudinal observational cohort study aiming to enrol 400 Black/African American and Hispanic/Latinx individuals living with HIV in areas of the USA with high prevalence rates of HIV. Each participant will be asked to share at least 14 consecutive days of mobility data per month through the study app for 1 year and complete surveys at five time points (baseline, 3, 6, 9 and 12 months). …”
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1671
Lignin Unlocks Stealth Carbon Sinks in Cold Seeps via Microbial Enzymatic Gatekeeping
Published 2025-01-01“…Our findings establish 3 paradigm shifts: (a) The turnover rates of terrestrial organic carbon are likely underestimated in deep-sea ecosystems; (b) microbial consortia employ combinatorial enzymatic strategies distinct from terrestrial decomposition regimes; (c) methyl shunting from lignin breakdown primes methanogenic precursors, revealing cryptic linkages between refractory carbon cycling and greenhouse gas reservoirs.…”
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1672
Nutritional status, dietary inflammatory potential, and risk of osteosarcopenia: the Bushehr Elderly Health (BEH) program
Published 2025-06-01“…Abstract Background Osteosarcopenia is a growingly approved geriatric condition with a significant prevalence that contributes to higher rates of illness and death. Chronic inflammation and inadequate nutrition are key risk factors for numerous age-related diseases. …”
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1673
Ultrasound-activated miR-195-5p/shikonin nanobubbles remodel immunosuppressive microenvironment via immunogenic cell death to potentiate PD-1/PD-L1 blockade in hepatocellular carci...
Published 2025-10-01“…Despite the transformative clinical impact of programmed cell death ligand 1/programmed death 1 (PD-1/PD-L1) blockade in hepatocellular carcinoma (HCC), therapeutic efficacy remains limited by the tumor immunosuppressive microenvironment (TIME), with objective response rates persistently below 20 %. To address this critical clinical challenge, we engineered ultrasound (US)-responsive lipid nanobubbles (NBs) co-encapsulating microRNA (miR)-195-5p and shikonin (SK) (designated miR-195-5p/SK-NBs), a dual-functional platform designed to synergize PD-L1 suppression with immunogenic cell death (ICD). …”
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1674
Machine Learning-Based Intrusion Detection Systems for the Internet of Drones: A Systematic Literature Review
Published 2025-01-01“…Existing Intrusion Detection Systems (IDS) for IoD face several limitations, including high false positive rates, resource constraints of drones, limited adaptability to evolving attack patterns, and a lack of standardized datasets for benchmarking, despite ongoing research efforts. …”
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1675
Global collaboration and innovation in malignant cerebral edema research: a bibliometric perspective
Published 2025-07-01“…AimMalignant cerebral edema (MCE) is a life-threatening complication of acute brain injuries, with mortality rates exceeding 80% in the absence of treatment. …”
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1676
Profiles and kinetics of PgRNA and clinical characteristics in pregnant, postpartum, and non-pregnant women with chronic HBV infection
Published 2025-07-01“…Moreover, the detection rates of pgRNA, DNA, and HBeAg varied significantly across the three stages and different treatment regimens in CHB women. pgRNA was highly correlated with HBeAg, and a moderate correlation was found between pgRNA and HBV DNA levels. …”
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1677
The Risk of Vestibular Disorders with Semaglutide and Tirzepatide: Findings from a Large Real-World Cohort
Published 2025-04-01“…Tirzepatide users demonstrated similar patterns but lower absolute rates (0.10% at 6 months to 0.19% at 3 years vs. controls 0.04% to 0.15%), with hazard ratios from 3.19 (95% CI: 2.11–4.81) to 4.55 (95% CI: 3.43–6.03). …”
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1678
Analyzing the Contents of a Large, Public Online Peer Support Forum for Obsessive-Compulsive Disorder: Thematic Analysis
Published 2025-05-01“… Abstract BackgroundObsessive-compulsive disorder (OCD) is a debilitating chronic anxiety disorder with low rates of remission. r/OCD is a peer support forum hosted by the Reddit website with over 180,000 users and 100‐200 new posts daily. …”
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1679
Immunohistochemical analysis of IDH1, ATRX, p53, and Ki-67 in glioblastoma and diffuse infiltrative glioma: Therapeutic and prognostic correlation
Published 2025-01-01“…Kaplan-Meier method and Cox proportional regression model (forward model) were used to estimate the mean and median survival times, failure rates, and hazard ratios. Results. In the study, 115 (56.1%) patients were male and 90 (43.9%) were female. …”
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1680
Dietary strategies for preventing and managing obesity through evidence-based nutritional interventions
Published 2025-07-01“…This crisis is driven by multifaceted factors, including sedentary lifestyles, urbanization, dietary transitions, and behavioral influences. As obesity rates continue to rise, dietary interventions emerge as crucial and modifiable strategies for prevention and management. …”
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