Uncovering genetic contributors to developmental delay and intellectual disability: a focus on CNVs in pediatric patients by Yilun Tao, Yilun Tao, Hongzhi Guo, Dong Han, Miao Yang, Ting Lun, Lihong Wang, Wenxia Song, Haiwei Wang, Xiaoze Li

“…CNV pathogenicity was assessed using established databases and ACMG guidelines, with inheritance patterns determined where possible.ResultsAcross the 99 patients, 43 CNVs were identified in 40 individuals, with 32 classified as clinically significant, resulting in a diagnostic rate of 30.3%. …”
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Temperature drives the variations in cropland exposure to compound drought and heatwave events under future climate in Northeast China by Chuanwei Zhang, Jiangbo Gao, Lulu Liu, Yanjun Shen, Shaohong Wu

“…Notably, adherence to the SSP126 pathway can reduce both the increase rate of CDHW magnitude and cropland exposure compared to other SSPs. …”
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Organ-specific safety profile of bioinspired short antimicrobial peptides in zebrafish embryos by Sahar Isa Da’as, Sahar Isa Da’as, Hajira Afreen, Aseela Fathima, Ahmad M. Hani, Nura A. Mohamed, Md Mizanur Rahman, Patrick G. Burgon, Sergio Crovella, Haissam Abou-Saleh

“…Peptide E exhibited developmental toxicity at concentrations above 100 μg/mL, along with cardiotoxic effects such as reduced heart rate, variable locomotion patterns, and clear hepatotoxic responses.ConclusionThis study highlights distinct organ-specific toxicity profiles for Peptides C and E and underscores the importance of careful preclinical evaluation of BSAMPs. …”
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CFD, energy, and exergy analysis and sustainability indicators of tilapia fish strips drying using an evacuated tubes indirect solar dryer by Amena Ali Alsakran, Omar Shahat Younis, András Székács, Omar Saeed, Mohamed Hamdy Eid, Ali Majrashi, Atef Fathy Ahmed, Aml Abubakr Tantawy, Abdallah Elshawadfy Elwakeel

“…The optimal air flow rate of 0.03 m3/s provided a uniform drying temperature of 74.82 °C, at solar noon. …”
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Landscape analysis of m6A modification regulators reveals LRPPRC as a key modulator in tubule cells for DKD: a multi-omics study by Li Jiang, Hongda Yu, Jie Jian, Xulin Sai, Yudian Wang, Yufei Zhang, Xiai Wu

“…In clinical patients, the expression levels of LRPPRC mRNA in DKD showed the tendency to be downregulated and exhibited the potential correlations with Glomerular Filtration Rate (GFR) and proteinuria according to the Nephroseq database. …”
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Integration Method with Backpropagation by Nidhal AL-Assady, Jamal Majeed, Shahbaa Khaleel

“…In this research, a new method is discovered (combined method) to accelerate the backpropagation network by using the expected values of source units for updating weights, we mean the expected value of unit by the sum of the output of the unit and its error term multiplied by the factor Beta to accelerate the algorithm and also adjust the value of learning coefficient continuously if the value of energy function E decreases the learning rate is increased by a factor , if the value of the energy function E increases , the value of the learning rate is decreased by a factor . …”
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Serum metabolic profiling enables diagnosis, prognosis, and monitoring for brainstem gliomas by Keke Li, Ruimin Wang, Zhengying Gu, Wenyun Weng, Wanshan Liu, Yida Huang, Jiao Wu, Ziyue Zhang, Shouzhi Yang, Jun Su, Yujie Tang, Kun Qian, Mawei Jiang, Lin Huang, Jingjing Wan

“…Abstract Brainstem gliomas (BSG) is a highly malignant central nervous system childhood tumors with 5-year survival rate <10%. Metabolism during radiotherapy is a dynamic and precisely programmed process, improving clinical outcomes and guiding therapy decisions of BSG. …”
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The Neural Basis of Salt Perception: A Focus on Potassium Chloride as a Sodium Alternative by Emilia Iannilli, Raffaela Fürer, Antje Welge-Lüssen, Thomas Hummel

“…This study investigates the neural correlates of taste perception for NaCl, KCl, and their mixture using gustatory event-related potentials (ERPs) in a sample of 28 healthy young adults. Participants rated the intensity, saltiness, and pleasantness of the stimuli, which were matched for iso-intensity and iso-pleasantness. …”
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Optimizing jacket design for two-wheeler delivery workers during rainy conditions by Sujin Lim, Jisoo Ha

“…Also riders to make as many deliveries as possible and receive good ratings, most work more than 8 h. This complex work environment and long working hours expose them to physical fatigue, scrapes, bumps, falls, and other accidents, making it more necessary than ever to pay attention to the health and safety of delivery riders. …”
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Prevention of fetal brain injury in category II tracings by Masahiro Nakao, Michael G. Ross, Shoichi Magawa, Satoshi Toyokawa, Kiyotake Ichizuka, Naohiro Kanayama, Shoji Satoh, Nanako Tamiya, Akihito Nakai, Keiya Fujimori, Tsugio Maeda, Akira Oka, Hideaki Suzuki, Mitsutoshi Iwashita, Tomoaki Ikeda

“…Cases included those presumed to have an intrapartum onset of hypoxic–ischemic insult based on the fetal heart rate pattern evolution from reassuring to an abnormal pattern during delivery, in association with category II tracings marked by recurrent decelerations and an umbilical arterial BDecf ≥ 12 mEq/L. …”
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Emotional Interactive Simulation System of English Speech Recognition in Virtual Context by Dan Li

“…The experiments of feature extraction and pattern recognition of speech samples prove that Hidden Markovian has higher recognition rate and better recognition effect in speech emotion recognition. …”
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Systematic Review of Hospital Readmissions in Stroke Patients by Ahsan Rao, Emily Barrow, Sabine Vuik, Ara Darzi, Paul Aylin

“…Common risk factors associated with the change of readmission rate were also examined. Methods. The literature search was conducted from 15 February to 15 March 2016 using various databases, such as Medline, Embase, and Web of Science. …”
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Emotional and visual responses to trypophobic images with object, animal, or human body backgrounds: an eye-tracking study by Pengfei Yu, Li Yu, Li Yu, Yuting Li, Cheng Qian, Jia Hu, Weiyi Zhu, Fang Liu, Fang Liu, Qi Wang, Qi Wang, Qi Wang

“…Finally, participants rated the image’s disgust and arousal levels using a self-assessment rating scale. …”
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Exploring the Current Applications and Future Implications of Artificial Intelligence in Public Health Dentistry: A Narrative Review by Tanushri Mahendra Dalvi, Rajeshri Kotwadekar, Shrivardhan R Kalghatgi, Priyanka Paul Madhu, Priyanka Methildeotare

“…Artificial Intelligence (AI) is transforming healthcare at a rapid rate by enhancing disease prevention, diagnosis, treatment planning and management of health systems. …”
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Transcriptomic and Metabolomic Joint Analysis Revealing Different Metabolic Pathways and Genes Dynamically Regulating Bitter Gourd (<i>Momordica charantia</i> L.) Fruit Growth and... by Boyin Qiu, Dazhong Li, Qianrong Zhang, Hui Lin, Yongping Li, Qingfang Wen, Haisheng Zhu

“…The results revealed that the growth rate of fruit’s fresh weight, length, diameter, and flesh thickness during the first seven days was slow, and that it then rapidly increased after the seventh day, and finally slowed once more after 17 days, indicating that the overall process followed a “slow–fast–slow” pattern. …”
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Characterization of ion track-etched conical nanopores in thermal and PECVD SiO2 using small angle X-ray scattering by Shankar Dutt, Rudradeep Chakraborty, Christian Notthoff, Pablo Mota-Santiago, Christina Trautmann, Patrick Kluth

“…The track-to-bulk etching rate ratio is significantly different for the two materials, producing nanopores with cone angles that differ by almost a factor of two. …”
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Optimisation tools for meeting nutrient requirements of Indian children and adults at optimal cost by Fathima Ayoob, Jawahar R. Manivannan, Ashikh Ahmed, Afsal K. Murikkanchery, Abhishek Kumar, Santu Ghosh, Patrick Webb, Anura V. Kurpad, Tinku Thomas

“…Based on food prices from June 2022, the FOP tool generated optimised diets for 1–3-year-old Bihari children priced at INR 26·8 (USD 0·32 converted as of January 2024 rate)/child/day. By applying a milk subsidy, this cost could drop to INR 23·7 (USD 0·28). …”
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The characteristics of Korean elderly multiple myeloma patients aged 80 years or over by Sang Hwan Lee, Hee-Jeong Cho, Joon Ho Moon, Ji Yoon Jung, Min Kyoung Kim, Mi Hwa Heo, Young Rok Do, Yunhwi Hwang, Sung Hwa Bae

“…The early mortality (EM) rate was 28.3%. Conclusions Even in patients with MM aged 80 years or over, chemotherapy can result in better survival outcomes than supportive care. …”
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A country-wide survey into the composition and transformation of short-chain organic acids in anaerobic sludge digesters at wastewater treatment plants in Denmark by Zijun Li, Morten Kam Dahl Dueholm, Chenjing Jiang, Bihe Zhu, Lei Liu, Per Halkjær Nielsen, Liping Hao

“…Abstract Short chain organic acids (SCOAs) containing 1–6 carbons are important intermediates in anaerobic digestion (AD) of sewage sludge, and transformation of SCOAs is often the rate-limiting step. Comprehensive information about SCOAs in full-scale anaerobic digesters is thus crucial to better monitor and regulate the AD process. …”
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Electrospinning of Chitosan–Halloysite Nanotube Biohybrid Mats for Clobetasol Propionate Delivery by Natallia V. Dubashynskaya, Valentina A. Petrova, Igor V. Kudryavtsev, Andrey S. Trulioff, Artem A. Rubinstein, Alexey S. Golovkin, Alexander I. Mishanin, Anton A. Murav’ev, Iosif V. Gofman, Daria N. Poshina, Yury A. Skorik

“…The optimized composition of the electrospinning solution was determined: 2.4% solution of CS in 46% acetic acid with addition of PEO (10% of CS mass) and HNTs (5% of CS mass); CP was introduced as an ethanol solution at the rate of 2 mg CP per 1 g of the obtained nonwoven material. …”
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