Acoustic and Natural Language Markers for Bipolar Disorder: A Pilot, mHealth Cross-Sectional Study by Cristina Crocamo, Riccardo Matteo Cioni, Aurelia Canestro, Christian Nasti, Dario Palpella, Susanna Piacenti, Alessandra Bartoccetti, Martina Re, Valentina Simonetti, Chiara Barattieri di San Pietro, Maria Bulgheroni, Francesco Bartoli, Giuseppe Carrà

“…Symptom severity assessment was based on clinician ratings, using the Young Mania Rating Scale (YMRS) and Montgomery-Åsberg Depression Rating Scale (MADRS) for manic and depressive symptoms, respectively. …”
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Airway-microbiome-driven mechanisms of disease during optimised self-management: a lesson learned from mechanistic study of the Colour-COPD trial by Alice M Turner, Daniella Spittle, Karl Staples, David Cleary

“…Analysis of the microbial patterns, which would have been obtained from the respiratory microbiome, will be compared to antibiotic consumption for acute exacerbation of chronic obstructive pulmonary disease (days/year) steroid load (days/year and mg/year), acute exacerbation of chronic obstructive pulmonary disease rate, forced expiratory volume in 1 second and longitudinally within individuals to determine the impact of frequent courses of antibiotics at group and individual level. …”
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An integrative scoring approach for prioritization of rare autism spectrum disorder candidate variants from whole exome sequencing data by Apurba Shil, Noa Arava, Noam Levi, Liron Levine, Hava Golan, Gal Meiri, Analya Michaelovski, Yair Tsadaka, Adi Aran, Idan Menashe

“…We developed AutScore and AutScore.r and assigned each variant based on their pathogenicity, clinical relevance, gene-disease association, and inheritance patterns. Finally, we compared the performance of both AutScore versions with the rating of clinical experts and the NDD variant prioritization algorithm, AutoCaSc. …”
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Efficacy of Ginkgo biloba on parameters in glaucoma: A systematic review. by Julia Prinz, Verena Prokosch, Xiaosha Wang, Yuan Feng, Peter Walter, Matthias Fuest, Filippo Migliorini

“…All clinical studies investigating the efficacy of GBE administration on the intraocular pressure (IOP), the corrected pattern standard deviation (CPSD) and the mean deviation of visual field testing, and heart rate were considered. …”
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Lake Evaporation and Its Effects on Basin Evapotranspiration and Lake Water Storage on the Inner Tibetan Plateau by Liuming Wang, Junxiao Wang, Lachun Wang, Liping Zhu, Xingong Li

“…The spatial pattern of the effect is mainly controlled by α, and the increasing trend of α (0.6%/10 a) also dominated the increasing trend in regional ETB rate (0.30 mm/a) though with large spatial heterogeneity. …”
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Multimodal analysis of cell-free DNA enhances differentiation of early-stage breast cancer from benign lesions and healthy individuals by Thi Tuong Vi Van, Trung Hieu Tran, Thi Hue Hanh Nguyen, Van Thien Chi Nguyen, Dac Ho Vo, Giang Thi Huong Nguyen, Trong Hieu Nguyen, Kim Sang To, Anh Luan Nguyen, Cao Hong An Tran, Thanh Xuan Jasmine, Thi Loan Vo, Thi Huong Thoang Nai, Thuy Trang Tran, My Hoang Truong, Ngan Chau Tran, Thi Loc Le, Thi Hong Nhung Nguyen, Ngoc Hieu Tu, Thanh Son Tran, Bao Toan Le, Van Phong Tang, Pham Thanh Nhan Nguyen, Khac Tien Nguyen, Van Chien Ho, Xuan Vinh Nguyen, Nhu Nhat Tan Doan, Thi Trang Tran, Thi Minh Thu Tran, Vu Uyen Tran, Minh Phong Le, Thi Luyen Vu, Ba Linh Tieu, Huu Tam Phuc Nguyen, Luu Hong Dang Nguyen, Ngoc Minh Phan, Thi Van Phan, Thi Thanh Thuy Do, Thi Huyen Dao, Hung Sang Tang, Duy Sinh Nguyen, Hoa Giang, Minh Duy Phan, Hoai-Nghia Nguyen, Duc Hieu Vo, Le Son Tran

“…Conclusions These findings underscore the potential of cfDNA biomarkers to enhance BC detection and reduce the rate of unnecessary biopsies.…”
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Brain-based gene expression and corresponding behavioural relevance of risk genes for broad antisocial behaviour by Jaroslav Rokicki, Megan L. Campbell, Dennis van der Meer, Alina I. Sartorius, Natalia Tesli, Piotr Jahołkowski, Alexey Shadrin, Ole Andreassen, Lars T. Westlye, Daniel S. Quintana, Unn K. Haukvik

“…Certain genes like NTN1, SMAD5, NCAM2, and CDC42EP3 displayed specificity for cognitive terms including chronic pain, heart rate, and aphasia. These expression patterns aligned with neurocognitive domains related to thinking, and learning, distress, motor skills, as determined by fMRI analysis. …”
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Experimental Study on Temperature-time Characteristics of Loess under the Freeze-Thaw Cycles by Cao Xueye, Zhang Eryuan, Bai Xiaopeng, Ji Jiaqiang, Sun Jielong

“…The change pattern of the thawing curve remained consistent across various w, with only a certain extent of influence on the rate of change. …”
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Pharmacoepidemiological analysis of routine management of heart failure patients in the Russian Federation. Part I by Yu. M. Lopatin, S. V. Nedogoda, M. V. Arkhipov, A. S. Galyavich, N. A. Koziolova, N. G. Lozhkina, E. V. Reznik, A. S. Salasyuk, M. Yu. Frolov, A. I. Chesnikova, E. V. Chumachek, L. A. Shpagina

“…There was sufficient follow-up rate, but the extent examinations do not correspond to the recommended one. …”
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Functional Connectivity Biomarker Extraction for Schizophrenia Based on Energy Landscape Machine Learning Techniques by Janerra D. Allen, Sravani Varanasi, Fei Han, L. Elliot Hong, Fow-Sen Choa

“…However, significant patient and control differences were found for the brief psychiatric rating scale (BPRS), auditory perceptual trait and state (APTS), visual perceptual trait and state (VPTS), working memory score, and processing speed score. …”
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Thermal comfort and energy related occupancy behavior in Dutch residential dwellings by Anastasios Ioannou

“…Specifically in houses with a good energy rating, the neutral temperature was higher than in houses with a poor rating. …”
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Real-world effectiveness of post-trastuzumab emtansine treatment for human epidermal growth factor receptor 2-positive metastatic breast cancer: a multicenter, matched cohort analy... by C. Courtinard, V. Barbet, R. Schiappa, F. Pilleul, S. Michiels, S. Dabakuyo, S. Gourgou, A. Jaffre, B. Asselain, L. Bosquet, K. Dunton, M. Rosenlund, Z. Liang, J. Cathcart, S. Delaloge

“…Patients and methods: Patients from the French Epidemiology Strategy and Medical Economics (ESME) mBC database who initiated treatment for HER2+ mBC between 1 January 2008 and 31 December 2016, and received one or more treatment lines following T-DM1 were propensity score matched 1 : 1 to patients from DESTINY-Breast01 to create an ESME DB-01 matched cohort. Treatment patterns, real-world best overall response, real-world objective response rate (rwORR), real-world disease control rate (rwDCR), real-world progression-free survival (rwPFS), and overall survival (OS) were estimated, including by prior pertuzumab exposure and de novo/relapsed mBC status. …”
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Candidate circRNAs related to skeletal muscle development in Dazu black goats by Chengli Liu, Pu Yang, Xiao Wang, Baiju Xiang, Guangxin E, Yongfu Huang

“…Furthermore, the expression pattern of 10 DEcircRNAs with RT-qPCR was verified, which showed 80% concordance rate with that of RNA_seq datasets. …”
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Dual-omics analysis reveals B vitamin regulation and metabolism in Areca Catechu inflorescence by Wenxiu Jiang, Xiaoxia Liu, Weiying Li, Jing Yang, Panjing Li, Minggeng Xie, Guangzhen Zhou

“…Notably, we characterized a key rate-limiting enzyme in the thiamine biosynthesis pathway, the thiazole synthase (AcTHI1), that plays a crucial role in regulating thiamine biosynthesis. …”
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Differential Cortical Responses of Functional and Sensory Electrical Stimulation in Closed-Loop Tremor Suppression for Parkinson’s Disease by Xiaoqi Zhao, Tinglan Huang, Mengyue Jin, Hongbo Zhao, Yu Shi, Yanlin Wang, Xiao Shen, Zhen Li, Qingqing Shi, Xiaodong Zhu, Lin Meng

“…Both FES and SES significantly reduced tremor amplitude, with FES showing overall greater suppression (hand suppression rate: 60.72% vs. 48.31%, p >0.05; forearm suppression rate: 62.25% vs. 54.41%, p >0.05) where substantial inter-individual variability was observed. …”
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Timing of Surgery and Preoperative Predictors of Surgical Site Infections for Patients with Depressed Skull Fractures in a Sub-Saharan Tertiary Hospital: A Prospective Cohort Study by Hervé Monka Lekuya, Jelle Vandersteene, Larrey Kasereka Kamabu, Rose Nantambi, Ronald Mbiine, Anthony Kirabira, Fredrick Makumbi, Stephen Cose, David Patrick Kateete, Mark Kaddumukasa, Edward Baert, Moses Galukande, Jean-Pierre Okito Kalala

“…The group of surgical intervention >48 h had an increased incidence of SSI (57.3% vs. 42.7%, p = 0.006), a longer median of postoperative hospital stay (8[IQR = 6–12] days versus 5 [IQR = 4–9], [p < 0.001]), and a higher rate of reoperation (71.4% vs. 28.6%, p = 0.05) in comparison with the group of ≤48 h. …”
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Annual dialysis data report 2022, Japanese Society for Dialysis Therapy (JSDT) Renal Data Registry by Norio Hanafusa, Masanori Abe, Nobuhiko Joki, Junichi Hoshino, Masatomo Taniguchi, Kan Kikuchi, Takeshi Hasegawa, Shunsuke Goto, Tetsuya Ogawa, Eiichiro Kanda, Shigeru Nakai, Toshihide Naganuma, Kenichiro Miura, Atsushi Wada, Yoshiaki Takemoto

“…The number of chronic dialysis patients was 347,474 at the end of 2022, marking the first decrease since the beginning of this survey. The prevalence rate of dialysis patients was 2781 per million population. …”
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Transdiagnostic body dissatisfaction: comparing adolescents with anorexia nervosa and depression during body exposure by Valeska Stonawski, Lena Sasse, Laura Derks, Gunther H. Moll, Oliver Kratz, Tanja Legenbauer, Stefanie Horndasch

“…BD was assessed with questionnaires; valence ratings were obtained for different body parts. Emotion ratings and gaze patterns towards the own body were assessed during each session via rating scales and eye-tracking. …”
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An Efficient RTL Design for a Wearable Brain–Computer Interface by Tahereh Vasei, Mohammad Ali Saber, Alireza Nahvy, Zainalabedin Navabi

“…To further illustrate the outperformance of our design, the proposed architecture is implemented on Virtex-7 field program gate array as a prototyping platform consuming 6 μJ energy with 1.52% area utilization.…”
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Experimental Study on the Effect of Freezing and Thawing on the Shear Strength of the Frozen Soil in Qinghai-Tibet Railway Embankment by B. Wang, J. H. Gao, Y. Q. Wang, X. J. Quan, Y. W. Gong, S. W. Zhou

“…After freezing-thawing action, it deserves to be mentioned that the cohesion increases slightly while the internal friction angles present a slight decrease trend compared to the initial state. (2) With the decrease in temperature and the gradual increase in cohesion, the temperature curve can be divided into a fast-growing section from 0 to −2°C, a slow-growing section from −2 to −8°C, and a second fast-growing section from −8 to −10°C owing to the combined effect of the pressure-thawing action and ice-water phase change. In addition, the rate of decrease in the internal friction angle also shows a similar pattern. (3) The cohesion and the internal friction angle of samples both tend to increase first and then decrease with the rise of the initial moisture content, and the critical initial moisture content is near the optimal moisture content of 15%. (4) Both the cohesion and the internal friction angle of the samples increase with dry density growth. …”
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