Machine learning-based source apportionment and source-oriented probabilistic ecological risk assessment of heavy metals in urban green spaces by Jun Li, Jia-Yi Lu, Xin-Ying Tuo, Chao Wang, Jun-Zhuo Liu, Zhan-Dong Gao, Cun-Hao Yu, Fei Zang

“…Results showed that the average concentrations of Cd (0.38 mg kg−1), Cu (35.51 mg kg−1), Hg (0.07 mg kg−1), Pb (34.59 mg kg−1), and Zn (130.58 mg kg−1) exceeded local soil background values, except for As (8.56 mg kg−1), Cr (62.77 mg kg−1), and Ni (27.68 mg kg−1). Notably, exceedance rates for Cd, Hg, Pb, and Zn were 90.91 %, 94.95 %, 80.81 %, and 87.88 %, respectively. …”
Get full text

The role of JPT1 in hepatocellular carcinoma: tumor progression, microtubule dynamics regulation, and potential mechanisms within the immune microenvironment by Yipin Lu, Peng Xu, Sha Li, Jie Yao

“…A pan-cancer analysis was performed to evaluate JPT1 expression patterns and prognostic value across multiple cancer types. …”
Get full text

Prediction efficiency and incremental processing strategy during spoken language comprehension in autistic children: an eye-tracking study by Zihui Hua, Tianbi Li, Ruoxi Shi, Ran Wei, Li Yi

“…However, autistic children exhibited reduced prediction efficiency compared to neurotypical peers, evidenced by significantly lower proportions of and slower growth rates in fixations to target objects relative to unrelated distractors, and delayed onset of predictive looking. …”
Get full text

Inflammatory markers mediate the association between alternative adiposity indices and mortality in patients with rheumatoid arthritis: data from NHANES 1999–2018 by Feng Luo, Jia-jie Guo, Xue-mei Yuan, Heng Zhou, Qiu-yi Wang, Chang-ming Chen, Xue-ming Yao, Wu-kai Ma

“…Conclusions This study revealed a potential clinical value of a new obesity index, specifically the ABSI, in predicting the survival rates among individuals with RA. Inflammatory markers appear to play a partial mediating role in this relationship. …”
Get full text

Spatial distribution and predictors of early childbearing among Ethiopian women: evidence from the 2016 Ethiopian Demographic and Health Survey by Amare Teshome Tefera, Fanuel Gashaw, Martha Solomon, Nebiyu Bekele, Shegaye Shumet, Tigist Mulugeta, Araya Mesfin Nigatu, Solomon Gedlu Nigatu

“…Abstract Background Age at first birth is a crucial factor in understanding fertility patterns within a population. Ethiopia reports high rates of maternal and child mortality alongside elevated fertility levels. …”
Get full text

Topologically Optimized Anthropomorphic Prosthetic Limb: Finite Element Analysis and Mechanical Evaluation Using Plantogram-Derived Foot Pressure Data by Ioannis Filippos Kyriakidis, Nikolaos Kladovasilakis, Marios Gavriilopoulos, Dimitrios Tzetzis, Eleftheria Maria Pechlivani, Konstantinos Tsongas

“…This innovative approach allows the development of tailored prosthetic limbs with optimal replication of the human motion patterns, resulting in improved patient outcomes and higher success rates. …”
Get full text

Real-Time Defect Detection for Fast-Moving Fabrics on Circular Knitting Machine Under Various Illumination Conditions by Yan-Qin Ni, Pei-Kai Huang, Ching-Han Yang, Chin-Chun Chang, Wei-Jen Wang, Deron Liang

“…Next, due to practical constraints aimed at maintaining high yield rates, collecting sufficient abnormal fabric samples for model training is costly and limited. …”
Get full text

Comparison of neoadjuvant chemoimmunotherapy with planned surgery and concurrent chemoradiation followed by immunotherapy for potentially resectable stage III non-small-cell lung c... by Yana Qi, Xiaoyang Zhai, Qinhao Xu, Yuqin Jin, Yingfan Guo, Miaoqing Zhao, Hui Zhu, Hongbo Guo

“…Median overall survival (OS) was NR in either group, with 3-year OS rates of 87.5% in the neoCT/IO group and 75.0% in the cCRT + IO group (p = 0.22). …”
Get full text

Epidemiological and clinical analysis, and outcomes of tuberculosis co-infection among people living with HIV in Türkiye (2014-2024) ClinSurv HIV cohort: A large case series. by Ali Mert, Okan Derin, Esra Zerdali, Abdurrahman Kaya, Özlem Gül, Deniz Borcak, Ahmet Furkan Kurt, Meliha Meriç Koç, Bircan Kayaaslan, Ayşe Batırel, Alper Gündüz, İnci Yılmaz Nakir, Gülşen Yörük, Dilek Yıldız Sevgi, Hayat Kumbasar Karaosmanoğlu, Bilgül Mete, Melike Nur Özçelik, Nagehan D Sarı, Yasemin Akkoyunlu, Fehmi Tabak

“…The positivity rates of Ehrlich-Ziehl-Neelsen staining (EZN), polymerase chain reaction (PCR), and TB cultures in clinical samples were found to be 47.5%, 72.5%, and 53%, respectively. …”
Get full text

Conversational AI agent for precision oncology: AI-HOPE-WNT integrates clinical and genomic data to investigate WNT pathway dysregulation in colorectal cancer by Ei-Wen Yang, Brigette Waldrup, Enrique Velazquez-Villarreal, Enrique Velazquez-Villarreal

“…Exploratory queries further assessed treatment response, co-mutation patterns, and population-specific trends.ResultsIn recapitulation analyses, AI-HOPE-WNT reproduced key trends from prior work, including improved survival in WNT-altered EOCRC and higher RNF43 mutation rates in Hispanic/Latino (H/L) populations compared to non-Hispanic White (NHW) people. …”
Get full text

Effects of timing of abomasal infusion of fatty acids on the daily rhythms of milk synthesis and plasma hormones and metabolites in dairy cows by I.J. Salfer, P.A. Bartell, K.J. Harvatine

“…Both de novo and mixed-source fatty acid yields were reduced by DAY and NGT, suggesting that the faster infusion rates may have resulted in concentrations of fatty acids that exceeded a threshold sufficient to inhibit de novo fatty acid synthesis. …”
Get full text

Estimating the burden of disease attributable to non-assisted suicide in Switzerland from 2009 to 2021: a secondary data analysis by Annora Mack, Sarah Rajkumar, Jacob Kofler, Kaspar Wyss

“…The stark sex disparity in suicide rates further underscores the need for sex-sensitive approaches. …”
Get full text

Heterogeneity of Candida bloodstream isolates in an academic medical center and affiliated hospitals by Nancy E. Scott, Elizabeth Wash, Christopher Zajac, Serin E. Erayil, Susan E. Kline, Anna Selmecki

“…Phenotypic data, including patterns of antifungal drug resistance, are limited. …”
Get full text

Gastric Cancer Mortality in Ceará in Brazil’s Northeastern, 2000-2022: Spatio- Temporal Study by Lucia Libanez Bessa Campelo Braga, Helio De Almeida Nobre Junior, Jorg Heukelbach, Anderson Fuentes Ferreira, Ana Suzete Lopes, Edson Luiz de Oliveira, Vitor de Sousa Tomé, Taynara Lais Silva, Daniele Calheiros Campelo Maia, Alberto Novaes Ramos Júnior

“…The highest mortality rates were found in the southern parts of the state and around a northern major urban center. …”
Get full text

Genomic data suggest parallel dental vestigialization within the xenarthran radiation by Emerling, Christopher A, Gibb, Gillian C, Tilak, Marie-Ka, Hughes, Jonathan J, Kuch, Melanie, Duggan, Ana T, Poinar, Hendrik N, Nachman, Michael W, Delsuc, Frédéric

“…These genomic data provide evidence for multiple pathways and rates of anatomical regression, and underscore the utility of using pseudogenes to reconstruct evolutionary history when fossils are sparse. …”
Get full text

Development of prediction models for screening depression and anxiety using smartphone and wearable-based digital phenotyping: protocol for the Smartphone and Wearable Assessment f... by Sujin Kim, Ah Young Kim, Yu-Bin Shin, Seonmin Kim, Min-Sup Shin, Jinhwa Choi, Kyung Lyun Lee, Jisu Lee, Sangwon Byun, Heon-Jeong Lee, Chul-Hyun Cho

“…However, their detection and diagnosis rates remain low owing to the limitations of the current screening methods. …”
Get full text

Treatment of unacceptable bleeding in long-term users of 52-mg levonorgestrel intrauterine device: a prospective observational studyAJOG Global Reports at a Glance by Patty A.H.H. van der Heijden, MD, Karlijn A. Röttgering, Tamara J. Oderkerk, MD, Jeanne P. Dieleman, Arianne C. Lim, PhD, Marlies Y. Bongers, PhD, Peggy M.A.J. Geomini, PhD

“…The secondary outcomes included the number of bleeding days 12 months after the start of medication, bleeding patterns, discontinuation rate of the 52-mg levonorgestrel intrauterine device, side effects, adverse events, and patient satisfaction at 3 and 12 months of follow-up. …”
Get full text

Characteristics and Outcomes of People With COPD Who Experience Exacerbations While on Inhaled Triple Therapy: Results of the SIRIUS I Cohort Study in the US (2015–2019) by Nordon C, Carstens D, Fagerås M, Müllerová H, Veeranki PS, Alves JA, Germack HD, Barnes TL, McCormack MC

“…Baseline characteristics and treatment patterns, crude incidence rates (IRs) for exacerbations and mortality (per 100 person-years [PYs]; variable follow-up), and HCRU and costs (12-month follow-up) were summarized descriptively.Results: Of 4,920 patients in the TT cohort, mean (SD) age was 62.3 (9.7) years, 60.9% were female, and 68.0% were white; 46.5% of TT cohort patients with a history of smoking were current smokers. …”
Get full text

Historical Overview of the Evolution of Multidrug-Resistant Gram-Negative Infections in Tunisia from 1999 to 2019 by Lamia Kanzari, Sana Ferjani, Basma Mnif, Faouzia Mahjoubi, Mariem Zribi, Khaoula Meftah, Asma Ferjani, Emna Mhiri, Yomna Ben Lamine, Yosr Kadri, Habiba Naija, Manel Hamdoun, Yosra Chebbi, Sarra Dhraief, Naglaa Mohamed, Hela Zaghden, Lamia Thabet, Wafa Achour, Olfa Bahri, Farouk Barguellil, Maha Mastouri, Sophia Besbes, Leila Slim, Hanen Smaoui, Adnene Hammami, Ilhem Boutiba-Ben Boubaker

“…<i>A. baumannii</i> had a high resistance rate to imipenem that increased from 34.5% in 2008 to 84.2% in 2019 and had low susceptibility rates to all other antibiotics tested. …”
Get full text

Widening gap in life expectancy between patients with heart failure living in most and least deprived areas: a longitudinal cohort study by O. I. Brown, M. Drozd, H. MacGowan, M. McGinlay, R. Burgess, S. Straw, A. D. Simms, V. K. Gatenby, A. Sengupta, A. M. N. Walker, C. Saunderson, M. F. Paton, K. I. Bridge, J. Gierula, K. K. Witte, R. M. Cubbon, M. T. Kearney

“…The primary outcome was all-cause mortality, and relative survival predictions—in relation to age- and sex-matched background mortality rates—were calculated using UK National Life Tables. …”
Get full text