Long-term effect of pegylated liposomal doxorubicin in recurrent platinum-resistant ovarian cancer: а clinical case by I. A. Pokataev, A. S. Tyulyandina, L. V. Chitia, S. A. Tyulyandin

“…Chemotherapy is a main treatment for recurrent OC. In Russia, the rate of platinum-resistant recurrences after first-line chemotherapy is more than 50 %, which may be due to the high extent of a tumor process at the moment of diagnosis, to the low rate of optimal cytoreductive interventions, and to non-optimal treatment. …”
Get full text

Temporal and Spatial Dynamics of Surface Water Temperature Changes in China's Major Lakes by Haimei Duan, Kun Yang, Xiaolu Zhou, Yi Luo

“…Particularly, when analyzing the spatial pattern based on China's famous population‐economic demarcation line (the Hu Huanyong Line), we found that the LSWT growth rate in lakes east of the Hu Huanyong Line is higher than that in lakes to the west in Phase II, as well as under the SSP1‐RCP2.6 and SSP2‐RCP4.5 scenario models. …”
Get full text

Effect of engine failure on aerodynamic characteristics of a light transport aircraft model by Yu. S. Mikhailov

“…If the half of engine thrust is lost, which adversely affects a rate of climb, the most critical flight modes are the take-off and go-around procedures performed at low altitudes using the engine asymmetric thrust. …”
Get full text

High-risk HPV distribution and importance of continuing cervical cancer screening of women aged 65 years and older: a study based on 2 152 766 women in China by Bo Wu, Yu Jiang, Jiahui Wang, Xiaotian Li, He Wang, Fanghui Zhao, Zichen Ye, Yingyu Zhong, Shuyan Jin, Xuelian Zhao, Yueyun Wang

“…The hr-HPV prevalence in women aged≥65 was 13.67%, with a CIN2+ detection rate of 3.33‰ and a cancer rate of 0.92‰, compared with 8.08%, 1.55‰ and 0.1‰, respectively, in women aged<65 (all p<0.001). …”
Get full text

Thermo-hydro-mechanical coupling mechanisms and sensitivity analysis of abandoned mine thermal energy storage systems by Liyuan LIU, Yaohui LI, Tao WANG, Tongbin ZHAO, Qiang KOU, Zerui MI, Le ZHANG

“…A three-dimensional thermo-hydro-mechanical (THM) coupled numerical model is developed to calculate the coupled effects over a decade of system operation and analyze heat transfer processes along with stress variation patterns in the roadway’s surrounding rock. Results indicate that the MTES system effectively utilizes geothermal environments for high-efficiency storage of waste heat, achieving a residual temperature of 35.5 ℃ (44.4% retention rate) during the first year following the injection of 80 ℃ water, with winter extraction temperatures progressively increasing annually. …”
Get full text

Photovoltaic Panel Efficiency Estimation with Artificial Neural Networks: Samples of Adiyaman, Malatya, and Sanliurfa by Yasin Icel, Mehmet Salih Mamis, Abdulcelil Bugutekin, Mehmet Ismail Gursoy

“…The amount of electric energy produced by photovoltaic panels depends on air temperature, humidity rate, wind velocity, photovoltaic module temperature, and particularly solar radiation. …”
Get full text

Stomatal–Hydraulic Coordination Mechanisms of Wheat in Response to Atmospheric–Soil Drought and Rewatering by Lijuan Wang, Yanqun Zhang, Hao Li, Xinlong Hu, Pancen Feng, Yan Mo, Shihong Gong

“…We investigated wheat’s hydraulic transport (leaf hydraulic conductance, <i>K</i>_leaf) and gas exchange (stomatal conductance, <i>g_s</i>; photosynthetic rate, <i>A</i>_n) responses to combined drought stress from atmospheric and soil conditions at the heading stage, as well as rewatering 55 days after treatment initiation. …”
Get full text

The state of cancer care in Russia: breast cancer. Epidemiology and survival of patients. The impact of the SARS-CoV-2-beta-coronavirus epidemic (clinical and population study) by V. M. Merabishvili, V. F. Semiglazov, A. V. Komiakhov, T. Yu. Semiglazova, P. V. Krivorotko, А. M. Belyaev

“…The one-year and five-year survival rate of breast cancer patients continues to grow.…”
Get full text

Dual Task Interference in Young, Middle-Age and Older Adults During Different Functional Mobility Tasks: A Cross Sectional Study by Tamara R. L. P. Tolotti, Ana Paula O. Barbosa, João Vítor E. H. Szortyka, Adriana T. de Lemos, Felipe de S. Stigger

“…The time taken to complete the mobility tasks was measured, while performance on secondary tasks was assessed based on the CTT rate, number of errors (SCWT and DST), and rate of recalled words (SVFT). …”
Get full text

Efficacy of Tuina Versus the Proprioceptive Neuromuscular Facilitation (PNF) Technique in Patients With Nonspecific Chronic Neck Pain: Protocol for a Randomized Controlled Trial by Kaiqi Fan, Aicheng Wang, Hainan Gao, Ting Yu, Xiangyu Zhu

“… BackgroundNonspecific chronic neck pain (NCNP), characterized by a long course, a high recurrence rate, and a young age of onset, causes a huge economic burden. …”
Get full text

Dynamical modeling of syncytial mitotic cycles in Drosophila embryos by Laurence Calzone, Denis Thieffry, John J Tyson, Bela Novak

“…The model can be used to predict the phenotypes of novel mutations and effective ranges of the unmeasured rate constants and transport coefficients in the proposed mechanism.…”
Get full text

Anaesthetic practices in non-operating room settings for paediatric patients: A prospective observational study by Nayana Amin, Pallavi Patil, Virinchi Sanapala

“…There were 221 adverse events in 117 patients. The incidence rate of patients experiencing at least one adverse event leading to morbidity was 3.22%. …”
Get full text

A Data-Driven Approach for Urban Heat Island Predictions: Rethinking the Evaluation Metrics and Data Preprocessing by Berk Kıvılcım, Patrick Erik Bradley

“…This strengthens the visual capturing of spatial relationships, and as a result the correlation rate between air temperature and building volume data is also increased. …”
Get full text

A mixture transmuted generalized extreme value distribution: Definition and properties by Yang Yu, Sun HongGuang, Xu Zheng

“…In this paper, the properties of the survival function, hazard rate function, mean and variance, and maximum likelihood estimations of the mixture transmuted generalized extreme value distribution are provided, also the corresponding equations are given.…”
Get full text

Community Clustering and Recommendation Toward Elderly Health Records: Probabilistic Representation Learning and Large Graph Search by Huijiong Ding

“…Validated on &#x003E;1M health records, the method achieves a 0.5049 Balanced Error Rate, outperforming six baselines across 42 health categories. …”
Get full text

An improved modeling approach to investigate biases in human random number generation. by Tim Angelike, Jochen Musch

“…The generalized distance parameter, and particularly the new cycling parameter, improved the fit of the model to human-generated sequences and the rate of successful predictions of the next choice from 14.09% to 26.48%, significantly exceeding the expected chance value of 1/9 = 11.1%. …”
Get full text

Using the superiorly based pharyngeal flap to surgically manage cleft velopharyngeal insufficiency: a cohort study by Marvee Turk, Pragaash Shanmuganathan, Carli Maddocks, David Chong

“…Repeat speech evaluation one year after surgery demonstrated correction of velopharyngeal insufficiency in 17 patients, representing a 94.4 per cent success rate. Furthermore, only two patients experienced postoperative snoring (11.1%). …”
Get full text

Rheology of rock–ice avalanche in a periodic chute flow by Zhiping Sun, Zhibo Dong

“…Depth-resolved profiles of six key parameters—velocity, solid volume fraction, shear stress, normal stress, shear rate, and inertia number—were recorded during steady flow conditions. …”
Get full text

Emergent behaviors in multiagent pursuit evasion games within a bounded 2D grid world by Sihan Xu, Zhaohui Dang

“…After training with MARL algorithms, pursuers achieved a 99.9% success rate in 1,000 randomized pursuit-evasion trials, demonstrating the effectiveness of the learned strategies. …”
Get full text

Clinical and pathomorphological parameters of brain death: from the origins of the concept to its use in organ transplantation by V. O. Tumanskyi, L. M. Tumanska

“…It has been established that the main criterion for the development of human biological death, which determines irreversible cardiac arrest and the impossibility of restoring spontaneous respiration, are irreversible destructive changes in the nuclei of the pons and medulla oblongata, which make up the cardio-respiratory center that regulates heart rate, vascular tone and blood pressure, and generating rhythm and breathing patterns. …”
Get full text