Role of Genetic and Epigenetic Factors and Mechanisms Involved in the Occurrence of Congenital Heart Diseases (CHD) by Fateme Tabrizi, Mehri Khatami, Mohammad Mehdi Heidari

“…Conclusion: Due to modern surgical techniques, the survival rate of affected infants is increasing. Deeper insight into the exact causes of this disease is crucial for diagnosing and identifying high-risk patients and improving preventive and therapeutic strategies for CHD. …”
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Indentation Relaxation Behavior of the Austenitic Heat-Resistant Steel Sanicro25 by Lin Tong, Cao Tieshan

“…The results show that: the hardness/stress and time patterns of indentation relaxation at different depths are in accordance with the relationship similar to that proposed by Choi; the stress index is about 7 according to the power rate relationship, and the relaxation coefficient μ is about 0.3, whose inverse matches well with the stress index obtained from the indentation creep test; there is a pile-up phenomenon at the edges of the residual indentation on the surface of the specimen, which is caused by plastic flow of the material along the direction of the indenter after the formation of a completely plastic region at the bottom of the indenter. …”
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Clinical benefit of tafasitamab plus lenalidomide in relapsed or refractory diffuse large Bcell lymphoma: real-world data from the EarlyMIND study by Gabriel Brisou, Jérôme Paillassa, Sophie Bernard, Olivier Tournilhac, Luc-Matthieu Fornecker, Frédéric Maloisel, Lauris Gastaud, Eric Durot, Adrian Tempescul, Thorsten Braun, Vadim Ivanov, Brieuc Cherel, Caroline Serrier, Jeremy Delage, Abderrazak El Yamani, Baptiste Delapierre, Laure Lebras, Elsa Lestang, Camille Villesuzanne, Philippe Agape, Guillaume Escure, Ludovic Fouillet, Christophe Nicol, Gaëlle Olivier, Anthony Levy, Anne-Sophie Le Bris, Ophélie Cassuto, Laura Jacquemelle, Corinne Haioun, Charles Herbaux

“…Approval was based on the L-MIND study, which demonstrated a 57.5% overall response rate (ORR), 41.3% complete response (CR) rate, 12.1 months median progression-free survival (PFS), and 33.5 months median overall survival (OS) at five years. …”
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HTLV-1 antibodies in serum and cerebrospinal fluid in tropical spastic paraparesis in Brazil by A. Spina-França, J. A. Livramento, L. R. Machado, H. R. Gomes, L. S. Vianna, L. H. M. Castro, J. P. S. Nobrega, L. A. Baciheschi

“…CSF patterns considered (cytology, protein content and gamma-globulins rate) were different between TSP group with HTLV-l antibodies in CSF and SP group with no HTLV-l antibodies detection either in serum or in CSF. …”
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Genome-Wide identification and salt stress-responsive expression dynamics of the HMGR gene family in Ziziphus jujuba var. spinosa. by Xiaohan Tang, Xiaojun Ma, Jun Cao, Xinhong Wang, Xuexiang Li, Xiaozhou Yang, Jing Shu

“…They also exhibit significant therapeutic potential in herbal medicine. 3-Hydroxy-3-methylglutaryl coenzyme A reductase (HMGR), a pivotal rate-limiting enzyme governing the initial stage of the mevalonate (MVA) pathway in triterpene saponin biosynthesis, remains uncharacterized in Ziziphus jujuba var. spinosa. …”
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Managing Soil Biota-Mediated Decomposition and Nutrient Mineralization in Sustainable Agroecosystems by Joann K. Whalen

“…Methods are proposed to determine the rates of decomposition and nutrient release from organic residues. …”
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GNSS VELOCITY AND STRAIN FIELD IN THE NORTHERN SUMATRA 15 YEARS AFTER THE 2004 M9.2 SUMATRA ANDAMAN EARTHQUAKE by S. M. Alif, O. Anggara, M. F. Jihad, R. S. Perdana

“…To do this, a comparison was made of velocities and strain rates over two periods. The velocities of 5.5 to 40.5 mm/yr and the strain rate up to 47.2 μstrain/yr were obtained from the recently acquired GNSS data. …”
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CTSS and CD53: Emerging m6A methylation markers in diabetic kidney disease pathogenesis and their clinical implications by Meng Leilei, Huang Bin, Li Rui, Wenjie Wen

“…CTSS and CD53 were identified as potential biomarkers and validated in diabetic mouse models, showing negative correlations with glomerular filtration rate. Conclusions This study reveals two m6A methylation patterns in DKD, with one associated with increased immune infiltration. …”
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Spike Timing-Dependent Plasticity and Random Inputs Shape Interspike Interval Regularity of Model STN Neurons by Thoa Thieu, Roderick Melnik

“…Furthermore, at fixed input noise levels, the model’s output closely matches experimental firing rate and ISI variability data from PD patients and animals, with statistical tests confirming significant effects of STDP on firing regularity. …”
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Passive Sensing for Mental Health Monitoring Using Machine Learning With Wearables and Smartphones: Scoping Review by ShiYing Shen, Wenhao Qi, Jianwen Zeng, Sixie Li, Xin Liu, Xiaohong Zhu, Chaoqun Dong, Bin Wang, Yankai Shi, Jiani Yao, Bingsheng Wang, Xiajing Lou, Simin Gu, Pan Li, Jinghua Wang, Guowei Jiang, Shihua Cao

“…These findings underscore the technology’s potential to transform mental health care through objective, continuous monitoring—particularly for depression (heart rate and step count biomarkers) and anxiety (sleep and social interaction patterns). …”
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EFFECT OF THE EXTENT OF MEDIASTINAL LYMPHODISSECTION ON THE RESULTS OF COMBINED MODALITY TREATMENT FOR STAGE IIIA (N2 ) NON-SMALL CELL LUNG CANCER by E. O. Mantsyrev, A. V. Vazhenin, O. A. Gladkov, A. A. Lukin, M. N. Mironchenko, Ya. A. Gnatyuk, S. N. Timofeev

“…The median disease progression-free survival was 31 months and 14.5 months and the overall 5-year survival rates were 43,4 % and 16 %, respectively (p<0,05). …”
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Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function. by Wenbo Tang, Matthew Kowgier, Daan W Loth, María Soler Artigas, Bonnie R Joubert, Emily Hodge, Sina A Gharib, Albert V Smith, Ingo Ruczinski, Vilmundur Gudnason, Rasika A Mathias, Tamara B Harris, Nadia N Hansel, Lenore J Launer, Kathleen C Barnes, Joyanna G Hansen, Eva Albrecht, Melinda C Aldrich, Michael Allerhand, R Graham Barr, Guy G Brusselle, David J Couper, Ivan Curjuric, Gail Davies, Ian J Deary, Josée Dupuis, Tove Fall, Millennia Foy, Nora Franceschini, Wei Gao, Sven Gläser, Xiangjun Gu, Dana B Hancock, Joachim Heinrich, Albert Hofman, Medea Imboden, Erik Ingelsson, Alan James, Stefan Karrasch, Beate Koch, Stephen B Kritchevsky, Ashish Kumar, Lies Lahousse, Guo Li, Lars Lind, Cecilia Lindgren, Yongmei Liu, Kurt Lohman, Thomas Lumley, Wendy L McArdle, Bernd Meibohm, Andrew P Morris, Alanna C Morrison, Bill Musk, Kari E North, Lyle J Palmer, Nicole M Probst-Hensch, Bruce M Psaty, Fernando Rivadeneira, Jerome I Rotter, Holger Schulz, Lewis J Smith, Akshay Sood, John M Starr, David P Strachan, Alexander Teumer, André G Uitterlinden, Henry Völzke, Arend Voorman, Louise V Wain, Martin T Wells, Jemma B Wilk, O Dale Williams, Susan R Heckbert, Bruno H Stricker, Stephanie J London, Myriam Fornage, Martin D Tobin, George T O'Connor, Ian P Hall, Patricia A Cassano

“…As a secondary aim, we estimated the mean rate of decline in FEV1 by smoking pattern, irrespective of genotypes, across these 14 studies using meta-analysis.…”
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Temporal Trends in Acute Kidney Injury in Hospitalizations From 2009-2018 in Alberta: A Retrospective Population-Based Cohort Study by Anita Dahiya, Natasha Wiebe, Tyrone G. Harrison, Matthew T. James, Neesh Pannu

“…Furthermore, there was an overall increase in rates of AKI in patients aged younger than 60 and a decrease in the most elderly of patients in both the crude and adjusted data, suggesting potential changes in practice patterns and patient characteristics. …”
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An Unexplored Diversity for Adaptation of Germination to High Temperatures in Brassica Species by M. Tiret, M.‐H. Wagner, L. Gay, E. Chenel, A. Dupont, C. Falentin, L. Maillet, F. Gavory, K. Labadie, S. Ducournau, A.‐M. Chèvre

“…Our results show that both species exhibit heat tolerance to the temperature range tested, especially B. rapa, with an increase in speed and uniformity of germination time, as well as an increase in germination rate as temperature increased. As for B. oleracea accessions, the ability to germinate under heat conditions depended on the geographical origin; in particular, southern populations showed a higher germination rate than northern populations, possibly in relation to their warmer climates of origin. …”
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Planting Strategy Optimization Can Increase Maize Yield by Delaying Leaf Senescence and Improving Photosynthetic Capacity by Li Zhao, Xinrong Duan, Xinping Zhang, Xin Zhang, Linzhuan Song, Pei Chen, Min Liang, Chang Zhang, Chuangyun Wang

“…The results show that with the increase in planting density, the net photosynthetic rate of maize leaves gradually decreased, and the transpiration rate gradually increased. …”
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Assessing trends in clonorchiasis incidence via prescription data analysis in South Korea by Taeksang Lee, Jun Hyun Lee, Hanna Jin, Yun Kyung Lee, Hyun Beom Song

“…Methods We estimated the number of annual nationwide clonorchiasis cases by utilizing the National Health Insurance Service drug prescription information dataset for 2002–2023 and disease-specific prescription pattern. We then assessed trends in the overall incidence rates as well as sex-, age-, and region-specific incidence rates of clonorchiasis. …”
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Artificial Ventilation-Induced Acute Lung Lesion: Experimental, Morphological Study by A. M. Golubev, V. V. Moroz, D. V. Lysenko, A. N. Kuzovlev, D. A. Ostapchenko

“…Objective: to elucidate the pattern of morphological changes in the lung during artificial ventilation.Materials and methods. …”
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Research on Strata Movement Control in Deep Composite Lithologic Gangue Backfill Mining of Super-Thick and Weak Cementation Overburden Based on PFC–FLAC Coupling Simulation by Yonglei Li, Jiangning Gan, Guojian Zhang, Zhiyong Liu, Guangli Guo, Baode Guo, Shuo Sun

“…In addition, after calculation, the secondary compression rate of the composite rock gangue reaches 7% to 8%, ultimately leading to a secondary surface subsidence rate of 19%. …”
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Vegetation variations and driving mechanisms in northern China based on kNDVI by Zhuxia Xu, Weicheng Liu, Haiyan Li, Sanjie Qin, Tao Wen

“…Vegetation cover in northern China exhibits a fluctuating upward trend, with the northern Loess Plateau showing the highest rate of increase at 0.0032 per year and Southern Xinjiang and the Hexi Corridor showing the lowest rate of increase at 0.0003 per year. …”
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Statistical and numerical investigation of irreversibility for time-dependent Casson-Carreau nanofluid flow driven by curved surface: Regression analysis by P. Kumar, AR. Ajaykumar, F. Almeida, S. Saranya, Qasem Al-Mdallal

“…Identifying the parameters that optimize the heat transfer rate and using those parameters applying the appropriate statistical tool to optimize the heat transfer rate are the two motives behind this study. …”
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