Experimental Reconstruction of a Nineteenth Century Lower Limb Prosthetic Peg Leg – The Box Leg by Charlotte Waller-Cotterhill

“…However, that all societies (past and present) follow a single technological trajectory just at different rates of progress would be an inaccurate assumption (Pfaffenberger, 1992). …”
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Decoding Phthorimaea operculella (Lepidoptera: Gelechiidae) in the new age of change by Silvia I. RONDON

“…Scenarios of climate variation have increased the possibility of changes in pests' biological and ecological patterns by increasing or reducing overwintering length, changes in population growth rates, number of generations, crop-pest relationship, and therefore affecting their expansion. …”
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Full spectrum of novelties in time-dependent urn models by Alessandro Bellina, Giordano De Marzo, Vittorio Loreto

“…Systems driven by innovation, a pivotal force in human society, present various intriguing statistical regularities, from the Heaps' law to logarithmic scaling or somewhat different patterns for the innovation rates. The urn model with triggering (UMT) has been instrumental in modeling these innovation dynamics. …”
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Antibiotic resistance of biofilm-forming bacteria causing urinary tract infections: A systematic review by Abigail Anne Ferrer, Samson Decasa, Juliana Carlidy Elauria, Jalen Rose Esguerra, Earl Adriane Cano, Angela Nole Shayenne Coderos, Denise Alexandra Cruz, Den Marc Exala

“…Furthermore, biofilm formation rates ranged from 36.5% to 100%, with a median prevalence of 75.5%. …”
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Epidemiological and Socioeconomic Disparities in the 1742–1743 Epidemic: A Comparative Analysis of Urban Centers and Indigenous Populations Along the Royal Road by Jorge Hugo Villafañe

“…This study assessed excess mortality and socio-economic consequences across different population groups and settlement types. Results: Mortality rates increased dramatically—up to twelve times the pre-epidemic average in Cordova (Córdoba) and by 45% in Santa Fe—disproportionately affecting Indigenous and enslaved populations. …”
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Unraveling the Mechanistic Links Between Species Diversity and Infection Risk From Zoonotic Pathogens With Direct Transmission Among Reservoir Hosts: Rodent‐Orthohantavirus Systems... by Andreas Eleftheriou, Angela D. Luis

“…Although host regulation likely functions via density‐dependent transmission, and can thus change contact rates among hosts, consequences to other mechanisms have been neglected. …”
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Comprehensive multi-omics analysis of histone acetylation modulators identifies ASH1L as a novel aggressive marker for osteosarcoma by Chenlie Ni, Qiwen Sun, Haibo Yin

“…Abstract Background Osteosarcoma, a highly malignant bone tumor prevalent in children and adolescents, continues to have poor long-term survival rates, particularly in metastatic cases. While histone acetylation dysregulation has been implicated in cancer progression, the role of histone acetylation modification-related proteins (HAMRPs) in osteosarcoma immune infiltration and prognosis remains unclear. …”
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Economic growth and urban metamorphosis: A quarter century of transformations within the metropolitan area of Bucharest by Cristian Tosa, Andrei Mitrea, Hitomi Sato, Tomio Miwa, Takayuki Morikawa

“…Lately, these patterns have become manifest in Bucharest as well. …”
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A Data-Driven Analysis of Engineering Contract Risk Characterization Based on Judicial Cases of Disputes by Yongcheng Zhang, Ziyi Wu, Chaohua Xiong, Jianwei Wang, Maxwell Fordjour Antwi-Afari

“…The research identifies contractual risk characteristics across dimensions such as regional distribution, dispute terminology, legal citation patterns, and appellate role transitions. The key findings include the following: (1) Primary risks involve payment disputes, quality assurance failures, contractual validity issues, and schedule compliance challenges. (2) Litigation patterns reveal complex interdependencies between contracting parties and stakeholders, posing significant risk management challenges. (3) High second-instance modification rates stem from procedural irregularities, new evidence, improper legal application, and factual errors in initial trials. …”
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Environmental Factors Driving the Seasonal Dynamics of <i>Ixodes ricinus</i> and <i>Dermacentor reticulatus</i> in Eastern Poland by Aneta Woźniak, Zbigniew Zając, Joanna Kulisz

“…This study investigated their seasonal activity in Eastern Poland, a region with one of the highest incidence rates of tick-borne diseases nationwide. Additionally, we examined tick habitat preferences and the impact of abiotic factors on their activity patterns. …”
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Estimating medium-term (40 years) carbon uptake in living biomass from Life Terra’s afforestation and reforestation actions: challenges and recommendations by Jorge Palmero-Barrachina, Petr Blazek, Santiago Sabaté, Santiago Sabaté, Teresa Sauras-Yera, Samuel Allasia-Grau, Daniel Nadal-Sala, Daniel Nadal-Sala, Sven Kallen, Tiago de Santana, Emil Cienciala, Emil Cienciala

“…By year 40, individual tree biomass estimates ranged from 0.08 to 0.20 t/tree across regions and species types (conifers and broadleaves), with survival rates varying between 22.0 and 49.7%. This translated to stand-level biomass estimates of 54.7–232.6 t/ha at age 40 years. …”
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Targeted screening and single-cell analysis of genetic variants in melanoma using Mendelian randomization by Shi Li, Kaijiong Zhang, Guiji Zhang, Min Shi, Xing Yin, Bo Wang

“…Methods We combined SNP data from GTEx V8 eQTL and FinnGen databases for Mendelian randomization analysis, and performed single-cell analysis on melanoma samples. Results Melanoma rates were higher in men than women and increased with age. …”
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From access to reserve: antimicrobial resistance among etiological agents of central line-associated bloodstream infections in the view of WHO’s AWaRe antimicrobial spectrum by Anand, Gargee, Lahariya, Rijhul, Priyadarshi, Ketan, Sarfraz, Asim

“…Furthermore, a fluctuation in CLABSI rates was also observed, with a significant reduction in infection rates in 2024 after the implementation of enhanced infection control practices. …”
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Parsimonious and explainable machine learning for predicting mortality in patients post hip fracture surgery by Fouad Trad, Bassel Isber, Ryan Yammine, Khaled Hatoum, Dana Obeid, Mohammad Chahine, Rachid Haidar, Ghada El-Hajj Fuleihan, Ali Chehab

“…Abstract Hip fractures among the elderly population continue to present significant risks and high mortality rates despite advancements in surgical procedures. …”
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Primary Mediastinal Germ Cell Tumors: A Real-World Analysis of Clinical Characteristics, Treatment, and Survival Outcomes From Two Tertiary Cancer Centers in India by Bharath Gangadhar, Chitrakshi Nagpal, Aparna Sharma, Bivas Biswas, Somnath Roy, Aditya Bhagwat, Deepam Pushpam, Sameer Bakhshi, Sunil Kumar, Kunhi Parambath Haresh, Atul Batra

“…First-line chemotherapy comprised bleomycin, etoposide, and cisplatin (BEP; 60.5%) and etoposide, ifosfamide, and cisplatin (VIP; 27.8%). Response rates included complete response (25.3%) and partial response (54.4%). …”
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A computational DNA methylation method to remove contaminated DNA from spent embryo culture medium for noninvasive preimplantation genetic testingResearch in context by Yidong Chen, Jin Huang, Fuchou Tang, Lu Wen, Jie Qiao

“…By testing simulated SECM samples, the method demonstrated a substantial reduction in the false-negative rate even with up to 75% cumulus cell contamination. …”
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Race, gender and stroke subtypes mortality in São Paulo, Brazil Raça, gênero e mortalidade por subtipos da doença cerebrovascular em São Paulo, Brasil by Paulo A. Lotufo, Alessandra C. Goulart, Isabela M. Bensenor

“…For women, the rates were lower compared to men and the same pattern was observed among Black (125.4), Mixed (88.5) and White (64.1) women. …”
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Contributions of District Health Information Software 2 (DHIS2) to maternal and child health service performance in Ethiopia: an interrupted time series mixed-methods study by Taddese Alemu Zerfu, Moges Asressie, Amare Abera Tareke, Zenebu Begna, Tigist Habtamu, Netsanet Werkneh, Tariku Nigatu, Meskerem Jisso, Addisalem Genta

“…Specifically, DHIS2 led to increased monthly mean performance of key indicators such as antenatal care visits, skilled birth attendance, and immunization rates. Notable improvements in service delivery were observed, with significant increases in institutional delivery rates over time. …”
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Global, regional, and national burdens of traumatic brain injury, spinal cord injury, and skull fracture and their attributable risk factors from 1990 to 2021: a systematic analysi... by Yikang Wang

“…Data were presented as both numerical counts and age-standardized rates (ASRs) per 100,000 population, with corresponding uncertainty intervals. …”
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Costs and Resource Use Among Patients with Cervical Cancer, Cervical Intraepithelial Neoplasia, and Genital Warts in Algeria by Ali-Chakib Bennacef, Aomar Ammar Khodja, Fadl Allah Abou-Bekr, Tidiane Ndao, Ryan Holl, Goran Benčina

“…# Background Cervical cancer rates in North Africa have risen in the last 10 years, suggesting that this region might benefit from cervical cancer screening and HPV vaccination programs. …”
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