Dynamic immune response to Avian Pathogenic Escherichia coli infection in broiler chickens: Insights into pro-inflammatory and anti-inflammatory cytokine regulation by Xin Ye, Chuan-Yu Hsu, Linan Jia, Xue Zhang, Christopher Magee, Stephanie Whitham, Spencer Leigh, Jeffrey D. Evans, Li Zhang, Kelsy Robinson

“…This study investigates the dynamic immune responses to APEC infection in broiler chickens, with a focus on survival rates, airsac lesion scores, and cytokine gene expression patterns in lung tissue. …”
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Impact of Hepatic Steatosis on the Antiviral Effects of PEG-IFNα-2a in Patients with Chronic Hepatitis B and the Associated Mechanism by Huiqing Liang, Yaoyu Liu, Xiaoqian Jiang, Xiaoting Zheng, Jinmo Tang, Jiaen Yang, Hongli Zhuang, Penghua Lai, Li Peng, Zhenying Guo, Shanshan Cai, Dan Luo, Lingxia Xu, Qianguo Mao, Shaodong Chen

“…After 48 weeks of treatment and 24 weeks of follow-up, the rates of CR, VR, and BR had gradually decreased, whereas the severity of hepatic steatosis had increased. …”
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Resistome and Phylogenomics of <i>Escherichia coli</i> Strains Obtained from Diverse Sources in Jimma, Ethiopia by Mulatu Gashaw, Esayas Kebede Gudina, Guenter Froeschl, Ralph Matar, Solomon Ali, Liegl Gabriele, Amelie Hohensee, Thomas Seeholzer, Arne Kroidl, Andreas Wieser

“…<b>Introduction</b>: In recent years, antimicrobial resistance (AMR) rates have increased significantly in bacterial pathogens, particularly extended beta-lactam resistance. …”
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Global, regional, and national burden and trends of HIV/AIDS among women of childbearing age from 1990 to 2021: results from Global Burden of Disease 2021 by Mingjie Tang, Mingjie Tang, Jun Shao, Yanjie Jiang, Yanjie Jiang, Yinghong Li, Shiwei Li, Yilin Song, Wenxuan Wu, Jiqin Tang, Zhaoming Chen

“…In 2021, the global age-standardized rates for incidence (ASIR), prevalence (ASPR), mortality (ASMR), and DALYs (ASDALYR) were 34.73 (95% uncertainty interval [UI]: 30.03 to 40.54) per 100,000, 830.87 (95% UI: 784.57 to 884.29) per 100,000, 13.39 (95% UI: 10.34 to 17.56) per 100,000, and 829.75 (95% UI: 658.24 to 1,063.9) per 100,000, respectively. …”
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Giant Unicystic Ameloblastoma in a Teenager of Azande Tribe: A Clinical Case Report by Posite Charles M, Faustin TM, Woldemichael MA, Vargas Escalante E, Mohamud Snr MA, Laetitia FM, Moses A, Santos MB, Samuel T, Ali ZI, Olive MM, Maha AB, Baanitse J, Said M, Wabinga H, Rosales YD

“…Incidence varies globally, with lower rates in non-African populations (around 0.5 per million annually) compared to higher prevalence in Nigeria and South Africa, where Black populations show increased susceptibility. …”
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Work related musculoskeletal stress among residents of internal medicine on cardiological wards in their daily working practice – a kinematic and ergonomic analysis by Fabian Holzgreve, Corinna Rittinghausen, Ingo Hermanns, Britta Weber, Rolf Ellegast, Julia Bille, Doerthe Brueggmann, Stefanie Mache, David A. Groneberg, Daniela Ohlendorf

“…The office type work situations showed high sedentary rates with increased ergonomic risk for postures of the cervical and thoracolumbar spine (moderate to unfavorable postures for back curvature in almost all percentiles and office activities, reclination of the neck during (-8°- -16° in P05 and P25) for ‘use of computer’. …”
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Opportunities for immunocorrection aiming for reduction of morbidity in the areas with adverse occupational and environmental conditions by S. V. Petlenko, E. G. Golovacheva, O. I. Afanasieva

“…The one-year follow-up showed high effectiveness of these drugs, as shown by decreased incidence of acute infectious and lower exacerbation rates of chronic respiratory and gastrointestinal diseases. …”
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Organisation of physical education in universities for students with disabilities: Modular approach by L. V. Zakharova, O. N. Moskovchenko, U. Solimene, N. V. Tretyakova, N. V. Bannikova, N. V. Lyulina, O. A. Kattsin

“…The evaluation of the validity of differences in the average values of the studied indicators was performed according to Student’s t-test at a significance level of 5%. The growth rates of indicators were calculated according to Brody’s formula.Results and scientific novelty. …”
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Fungi present distinguishable isotopic signals in their lipids when grown on glycolytic versus tricarboxylic acid cycle intermediates by S. Jabinski, S. Jabinski, V. Kučera, V. Kučera, M. Kopáček, M. Kopáček, J. Jansa, T. B. Meador, T. B. Meador, T. B. Meador

“…<p>Microbial activity in soils controls both the size and turnover rates of large carbon (<span class="inline-formula">C</span>) inventories stored in the subsurface, having important consequences for partitioning of <span class="inline-formula">C</span> between terrestrial and atmospheric reservoirs as well as recycling of mineral nutrients such as nitrogen or phosphorus (often bound to the <span class="inline-formula">C</span>) that support plant growth. …”
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Emergency EEG: study of survival EEG de urgência: taxa de sobrevivência by Moacir Alves Borges, Harethusa Junia Botós, Ricardo Funes Bastos, Moacir Fernandes Godoy, Nely Silvia Aragão de Marchi

“…In the three months following EEG, a survival rate of 75% was found in patients with normal, discreet slow activity or intermittent rhythmic delta activity EEGs, of 50% for those with continuous delta activity and generalized epileptiform discharges, and of 25% for those with burst-suppression, diffuse depression, and in alpha/theta-pattern coma. …”
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Timing matters! Academic assessment changes throughout the day by Carmelo M. Vicario, Michael A. Nitsche, Chiara Lucifora, Pietro Perconti, Mohammad A. Salehinejad, Mohammad A. Salehinejad, Mohammad A. Salehinejad, Francesco Tomaiuolo, Simona Massimino, Alessio Avenanti, Alessio Avenanti, Massimo Mucciardi

“…Our results demonstrate a Gaussian distribution of passing rates throughout the day, with a significant peak at midday. …”
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Planned Liver Stereotactic Body Radiotherapy for Residual Colorectal Cancer Liver Metastases After Surgery: A Single-Arm Retrospective Study by Sixuan Li, Dezuo Dong, Xuan Zheng, Hongzhi Wang, Kun Wang, Baocai Xing, Weihu Wang

“…The 1-, and 2-year cumulative incidence rates of LF after SBRT were 7.7%, and 9.6%, respectively. …”
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Clinical features of patients with dysthymia in a large cohort of Han Chinese women with recurrent major depression. by Wenqing Wu, Zhoubing Wang, Yan Wei, Guanghua Zhang, Shenxun Shi, Jingfang Gao, Youhui Li, Ming Tao, Kerang Zhang, Xumei Wang, Chengge Gao, Lijun Yang, Kan Li, Jianguo Shi, Gang Wang, Lanfen Liu, Jinbei Zhang, Bo Du, Guoqing Jiang, Jianhua Shen, Ying Liu, Wei Liang, Jing Sun, Jian Hu, Tiebang Liu, Xueyi Wang, Guodong Miao, Huaqing Meng, Yi Li, Chunmei Hu, Yi Li, Guoping Huang, Gongying Li, Baowei Ha, Hong Deng, Qiyi Mei, Hui Zhong, Shugui Gao, Hong Sang, Yutang Zhang, Xiang Fang, Fengyu Yu, Donglin Yang, Tieqiao Liu, Yunchun Chen, Xiaohong Hong, Wenyuan Wu, Guibing Chen, Min Cai, Yan Song, Jiyang Pan, Jicheng Dong, Runde Pan, Wei Zhang, Zhenming Shen, Zhengrong Liu, Danhua Gu, Xiaoping Wang, Xiaojuan Liu, Qiwen Zhang, Yihan Li, Yiping Chen, Kenneth S Kendler, Jonathan Flint, Zhen Zhang

“…<h4>Conclusions</h4>There are increased rates of stressful life events in MDD with dysthymia, but the impact of life events on susceptibility to dysthymia with MDD differs from that seen for MDD alone. …”
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Toxicokinetics, tissue distribution, and toxic potency of PFOS alternative OBS in adult zebrafish (Danio rerio) based on flow-through exposure system by Yilong Zou, Yu Zhou, Xianglian Wang, Guiqing Gao, Gang Chen, Zhanmeng Liu, Mi Deng, Xueping Huang, Yongming Wu

“…Our findings indicate that OBS accumulated rapidly in zebrafish, with log kinetic bioconcentration factor (logBCFk) values ranging from 2.48 to 2.70 and slow elimination rates (ke = 0.0490–0.0643 d−1). The blood, liver, and muscle were responsible for over 50 % of the total body burden of OBS, with tissue concentrations decreasing in the following order: blood > liver > intestine > gills > gonad > brain > muscle, suggesting a tissue-specific accumulation pattern. …”
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The system of atmosphere, land, ice and ocean in the region near the 79N Glacier in northeast Greenland: synthesis and key findings from the Greenland Ice Sheet–Ocean Interaction (... by T. Kanzow, T. Kanzow, A. Humbert, A. Humbert, T. Mölg, M. Scheinert, M. Braun, H. Burchard, F. Doglioni, P. Hochreuther, M. Horwath, O. Huhn, M. Kappelsberger, J. Kusche, E. Loebel, K. Lutz, B. Marzeion, B. Marzeion, R. McPherson, M. Mohammadi-Aragh, M. Mohammadi-Aragh, M. Möller, M. Möller, C. Pickler, M. Reinert, M. Rhein, M. Rhein, M. Rückamp, M. Rückamp, J. Schaffer, J. Schaffer, M. Shafeeque, M. Shafeeque, S. Stolzenberger, R. Timmermann, J. Turton, J. Turton, C. Wekerle, O. Zeising

“…Observations and models employed in this study are consistent in terms of melt rates occurring below the floating ice tongue. Our results suggest that the multidecadal warming of Atlantic Intermediate Water flowing into the cavity below the ice tongue – supplied by the recirculating branch of the West Spitsbergen Current in Fram Strait – is the main driver of the recent major increase in basal melt rates. …”
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Relevance of Cellular Homeostasis-Related Gene Expression Signatures in Distinct Molecular Subtypes of Breast Cancer by Sharda P. Singh, Chathurika S. Dhanasekara, Michael W. Melkus, Chhanda Bose, Sonia Y. Khan, Flavia Sardela de Miranda, Maria F. Mahecha, Prrishti J. Gukhool, Sahil S. Tonk, Se-Ran Jun, Sahra Uygun, Rakhshanda Layeequr Rahman

“…Demographic factors such as age, race/ethnicity, menopausal status, and body mass index have been correlated with variations in incidence, mortality, and survival rates. Over the past decade, comprehensive genomic profiling has been widely used to identify molecular biomarkers and signatures to develop novel therapeutic strategies for patients. …”
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Multi-omics derivation of a core gene signature for predicting therapeutic response and characterizing immune dysregulation in inflammatory bowel disease by Mingming Wang, Liping Liang, Zibo Tang, Jimin Han, Lele Wu, Le Liu, Le Liu, Ye Chen, Ye Chen

“…Nomogram-based risk stratification effectively predicted biologic treatment responses across multiple therapeutic classes using four independent treatment datasets (GSE16879, GSE92415, GSE73661, GSE206285): low-risk patients demonstrated superior response rates to golimumab (63.3%), infliximab (54.8%), and vedolizumab (29% vs. 15% in high-risk group). …”
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Negative Regulation of <i>GmNAC35</i> by miR164 Enhances Drought Tolerance in Soybean by Wentao Hu, Man Zhang, Jie Lu, Miaomiao Zhang, Reqing He, Youlin Zhu, Dong Wang, Liyun Jiang

“…Conversely, <i>GmNAC35</i> showed an inverse pattern, indicating negative regulation by miR164. …”
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An integrated high-resolution bathymetric model for the Danube Delta system by L. Alaerts, L. Alaerts, J. Lambrechts, N. R. Randresihaja, N. R. Randresihaja, L. Vandenbulcke, O. Gourgue, E. Hanert, E. Hanert, M. Grégoire

“…These error rates are comparable to those observed in bathymetry interpolation in rivers with similar source datasets. …”
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Biomechanical evaluation of novel construct for stabilizing subcapital femoral neck fractures: a synthetic bone model by Anjan R. Shah, Miguel A. Diaz, Douglas L. Cerynik, Blake Schultz

“…Abstract Background High complication rates continue to be reported for femoral neck fractures, where moderate to severe shortening has been associated with pain and inferior functional outcomes. …”
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