FILAMIN A IN BREAST CANCER: FROM LITERATURE TO FUNCTIONAL INSIGHTS

“…While early-stage tumors often respond to treatment, progression to metastasis significantly lowers survival rates, highlighting the need for novel therapeutic approaches2. …”
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An Optimization Strategy for Truncating Ultralong Bus Lines Integrated with Metro Networks by Cuiying Song, Yujun Chen, Jihui Ma

“…For most ultralong bus lines, low punctuality rates and vehicle bunching are two main challenges. …”
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Radiotherapy combined with anlotinib for refractory leiomyosarcoma: a case report and literature review by Ziming Li, Xiuchun Yu, Ming Xu

“…Refractory leiomyosarcoma (LMS) is characterized by notoriously high recurrence rates and poses significant surgical challenges due to its anatomical complexity and invasive growth patterns. …”
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Increased Daytime Sleepiness in Patients with Childhood Craniopharyngioma and Hypothalamic Tumor Involvement: Review of the Literature and Perspectives by Hermann L. Müller

“…Childhood craniopharyngiomas are rare embryogenic malformations of the sellar region, presumably derived from Rathke cleft epithelium. The overall survival rates after neurosurgical intervention and/or irradiation are high (92%). …”
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Policing the Economy: Hyperinflation, Consumption and the Making of Austerity in Greater Buenos Aires, 1989-1991 by Jennifer Adair

“…DIPPBA officers tracked the fluctuating price of basic goods, rising rates of urban poverty, and sporadic outbreaks of supermarket lootings. …”
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Coastal aquifers key contributors to ocean chemistry through solute fluxes by Yael Kiro

“…Moreover, they are dynamically linked to sea-level changes: falling sea levels enhance SGD-driven solute inputs, whereas rising sea levels suppress them. These patterns suggest that SGD fluxes may regulate long-term climate trends, including rates of global cooling or warming.…”
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Cause-specific mortality in individuals with and without mental disorders according to socioeconomic position: a population-based cohort studyResearch in context by Danni Chen, Linda Ejlskov, Julie Werenberg Dreier, Natalie C. Momen, Lisbeth Mølgaard Laustsen, Henrik Toft Sørensen, Jayati Das-Munshi, Oleguer Plana-Ripoll

“…Summary: Background: Mental disorders are associated with elevated cause-specific mortality rates; however, the role of socioeconomic position (SEP) on these associations remains unclear. …”
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Cancer Burden in Chinese Older Adults: Insights Into Incidence, Mortality, and Global Comparisons Using GLOBOCAN 2022 by Yuanjie Zheng, He Li, Qianru Li, Siyi He, Yi Teng, Mengdi Cao, Nuopei Tan, Jiachen Wang, Tingting Zuo, Tianyi Li, Wanqing Chen

“…The estimated numbers of new cases and deaths, age‐standardized incidence rates (ASIRs), and age‐standardized mortality rates (ASMRs) were analyzed for the top ten cancer types in Chinese older adults, categorized by sex and age groups (60–69, 70–84, and 85+ years). …”
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Spatial Characterization of Channeling in Sheared Rough‐Walled Fractures in the Transition to Nonlinear Fluid Flow by Robert Egert, Fabian Nitschke, Maziar Gholami Korzani, Thomas Kohl

“…The small‐scale flow regime of both extreme cases tends to converge with increasing flow rates.…”
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Clinical Outcome and Molecular Profile in Patients with <i>DDX41</i> Mutation Hot-Spots by Nadia Toumeh, Yazan Jabban, Ahmad Nanaa, Rong He, David Viswanatha, Dragan Jevremovic, James M. Foran, Cecilia Y. Arana Yi, Antoine N. Saliba, Mehrdad Hefazi Torghabeh, William J. Hogan, Mithun V. Shah, Abhishek A. Mangaonkar, Mrinal M. Patnaik, Hassan B. Alkhateeb, Aref Al-Kali

“…We completed unadjusted comparisons using continuous or categorical variables, and survival rates were assessed using the Kaplan–Meier method and cox regression analysis. …”
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Trend analysis and epidemiological forecasting of colorectal Cancer mortality among reproductive-age women in sub-Saharan Africa by Jiefeng Zhao, Daxing Miao, Tao Yang, Jiang Chen, Xiangquan Lai

“…This study aimed to analyze CRC mortality trends, identify key driving factors, and predict future mortality patterns among women of childbearing age in SSA. Methods: We assessed CRC mortality among women of childbearing age across four SSA subregions and 46 countries, calculating age-standardized mortality rates (ASMR) and estimated annual percentage change (EAPC). …”
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Global, regional, and national burden of maternal disorders, 1990–2021: a systematic analysis from the global burden of disease study 2021 by Jie Huang, Yuanyuan Man, Zan Shi, Xiaojie Fu, Wenhao Shi, Xiaoling Liang

“…The Global Burden of Disease Study (GBD), recognized as the most comprehensive epidemiological surveillance system, provides critical evidence for optimizing maternal health policies through systematic quantification of disease burden patterns. This multinational study employs GBD 2021 data to conduct a spatiotemporal analysis of maternal disorder burden across 21 GBD regions and 204 countries and territories from 1990 to 2021, utilizing standardized metrics including DALYs, prevalence rates, and mortality incidence. …”
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TRNSYS-Based Performance Study of Solar-Assisted Single-Effect Absorption Cooling in Peshawar, Pakistan by Abid Hussain, Asnaf Aziz, Afzal Khan, Nadeem Ur Rehman, Hamza Pervez, Altaf Husain

“…Under variable load conditions, the auxiliary heater responded through frequent pulsed flow patterns, achieving peak flow rates up to 49,000 kg/hr without compromising outlet temperature. …”
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High prevalence of penicillin-resistant group B Streptococcus among pregnant women in Northwest Ethiopia by Getaneh Alemayehu, Alene Geteneh, Mesfin Dessale, Efrem Ayalew, Geberselasie Demeke, Alemayehu Reta, Mulugeta Kiros

“…In Ethiopia, reported GBS colonization rates among pregnant women range from 7.2 to 25.5%. …”
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Male Date Palm Chlorotype Selection Based on Fertility, Metaxenia, and Transcription Aspects by Hammadi Hamza, Mohamed Ali Benabderrahim, Achwak Boualleg, Federico Sebastiani, Faouzi Haouala, Mokhtar Rejili

“…Pollen viability varied significantly among cultivars, with P8 and B25 exhibiting the highest germination rates and pollen tube elongation, while C22 showed the lowest. …”
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A nationwide population-based cross-sectional time series study of hospitalized chronic liver disease burden in Thailand from 2017 to 2022 by Rungfah Saehan, Apichat Kaewdech, Pimsiri Sripongpun, Naichaya Chamroonkul, Teerha Piratvisuth, Suthat Liangpunsakul, Ponlagrit Kumwichar

“…Age- and sex-standardized incidence and mortality rates were assessed through descriptive and trend analyses, with LOESS smoothing applied to identify temporal patterns. …”
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Normotensive trauma patients with renal injuries: Hidden candidates for massive transfusion by Xin‐Hong Lin, Pi‐Chieh Lin, Ching‐Hua Tsai, Wei‐Ti Su, Shiun‐Yuan Hsu, Ching‐Hua Hsieh

“…Among MT patients, those with initial SBP ≥ 90 mmHg (n = 170) showed significantly higher rates of renal injuries (8.8% vs. 1.4%, p = 0.035) compared to those with SBP < 90 mmHg (n = 71). …”
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Burden and inequalities of chronic kidney disease attributable to diet globally, regionally and temporally, 1990–2021 by Nana Wei, Miao Yang, Pingping Zheng, Jian Xu

“…However, significant regional variations were observed in these rates, with Central Sub-Saharan Africa experiencing the highest and Eastern Europe the lowest. …”
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The administration sequences of immune checkpoint inhibitors and chemotherapy cause discrete efficacy when treating non-small cell lung cancer: a retrospective study by Bicheng Zhang, Yuxiao Song, Qian Min, Weiting Cheng, Jun Wang, Yang Fu, Jiaxin Yin

“…Additionally, the objective response rates (ORRs) for the three groups were 55.82% (72/129), 58.21% (39/67), and 68.92% (51/74), respectively. …”
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Еpidemiological aspects of ixodid tick-borne borrelioses in Kemerovo region by О. M. Drozdova, A. R. Efimova, Т. Е. Bondarenko, М. A. Shmakova

“…To study the epidemiological patterns of Lyme disease in the Kemerovo Region. Materials and Methods. …”
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