Clinical outcomes following PD-1 inhibitor elective discontinuation in cutaneous squamous cell carcinoma: exploring treatment de-escalation by Itamar Averbuch, Nofar Edri, Nethanel Asher, Gal Markel, Daniel Hendler, Hadas Ditzian Kugler, Eyal Yosefof, Noga Kurman

“…The purpose of this study was to evaluate the patterns of disease progression after anti-PD-1 therapy discontinuation in this group of patients. …”
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Optimizing jacket design for two-wheeler delivery workers during rainy conditions by Sujin Lim, Jisoo Ha

“…Also riders to make as many deliveries as possible and receive good ratings, most work more than 8 h. This complex work environment and long working hours expose them to physical fatigue, scrapes, bumps, falls, and other accidents, making it more necessary than ever to pay attention to the health and safety of delivery riders. …”
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Factors associated with the serum 25-hydroxyvitamin D levels in adults by Sue-Hsien Chen, Shu-Ching Chen, Yo-Ping Lai, Pin-Hsuan Chen, Kun-Yun Yeh

“…A self-reported depression rating score; health beliefs; and health-related quality of life (HRQoL) factors were assessed with questionnaires. …”
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Electrospinning of Chitosan–Halloysite Nanotube Biohybrid Mats for Clobetasol Propionate Delivery by Natallia V. Dubashynskaya, Valentina A. Petrova, Igor V. Kudryavtsev, Andrey S. Trulioff, Artem A. Rubinstein, Alexey S. Golovkin, Alexander I. Mishanin, Anton A. Murav’ev, Iosif V. Gofman, Daria N. Poshina, Yury A. Skorik

“…The optimized composition of the electrospinning solution was determined: 2.4% solution of CS in 46% acetic acid with addition of PEO (10% of CS mass) and HNTs (5% of CS mass); CP was introduced as an ethanol solution at the rate of 2 mg CP per 1 g of the obtained nonwoven material. …”
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Emotional and visual responses to trypophobic images with object, animal, or human body backgrounds: an eye-tracking study by Pengfei Yu, Li Yu, Li Yu, Yuting Li, Cheng Qian, Jia Hu, Weiyi Zhu, Fang Liu, Fang Liu, Qi Wang, Qi Wang, Qi Wang

“…Finally, participants rated the image’s disgust and arousal levels using a self-assessment rating scale. …”
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Thalamic nuclei volumes are related to disease stage in patients with amyotrophic lateral sclerosis by Tianrui Wen, Tianrui Wen, Jun Zhu, Jun Zhu, Sujuan Sun, Sujuan Sun, Yujing Chen, Yujing Chen, Ninglu Gao, Ninglu Gao, Mingjie Ma, Xinyue Chen, Shuangwu Liu, Shuangwu Liu, Pengfei Lin, Yan Deng

“…We investigated patterns of thalamic atrophy in the patients and in 94 healthy controls (HCs). …”
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Wetland key habitat functional areas in China informed by flagship waterbirds: Past changes, present status and future trend with modeling scenarios by Hengxing Xiang, Dehua Mao, Ming Wang, Yeqiao Wang, Chi-Yeung Choi, Wenjuan Wang, Haitao Wu, Kaidong Feng, Zongming Wang

“…The results of this study establish conservation priorities that align with national goals of a 55 % wetland protection rate and the global biodiversity framework in protected areas and biodiversity, indicating that the spatial conservation optimization approach is an effective method for identifying wetland KHFAs.…”
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Emotional Interactive Simulation System of English Speech Recognition in Virtual Context by Dan Li

“…The experiments of feature extraction and pattern recognition of speech samples prove that Hidden Markovian has higher recognition rate and better recognition effect in speech emotion recognition. …”
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The burden dynamics of leukemia in China from 1990 to 2021: an epidemiological analysis of trends, risk factors, and projections to 2036 by Renfang Zhang, Chunyue Guo, Yifang Liang, Siyu Qing, Ziyue Liang, Yongbin Wang, Chenguang Zhang

“…Objective: Leukemia is a key public health challenge in China, with epidemiological patterns shifting due to demographics, environment, and healthcare advances. …”
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Enhanced selective recovery of powder carrier-supported biofilms for enrichment of denitrifying functional bacteria by Chengxian Wang, Bin Lu, Boran Wu, Jin Chen, Zhigen Wu, Hongbo Han, Xiaohu Dai, Xiaoli Chai, Dian Hu

“…Compared to overflow sludge, underflow sludge (biofilm) exhibited a 33 % increase in particle size and a 0.51-fold increase in denitrification rate constants, leading to improvements of nitrogen and phosphorus removal efficiencies exceeding 73 %. …”
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Intelligent prediction of thyroid cancer in China based on GBD data and hospital electronic medical records: disease burden analysis combined with multiple machine learning models by Lina Yang, Shixia Zhang, Xinguo Wang, Jianjun Yang, Mengya Chen

“…It comprehensively reveals the disease burden trend of thyroid cancer in China, predicts the mortality rate of thyroid cancer in China, and emphasizes the causal role of high BMI as an important controllable risk factor. …”
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Unmasking insider threats using a robust hybrid optimized generative pretrained neural network approach by P. Lavanya, H. Anila Glory, Manuj Aggarwal, V. S. Shankar Sriram

“…The structure of the proposed approach involves three phases: (1) Chebyshev Graph Laplacian Eigenmaps solver (CGLE) for selecting the user-designated samples by reducing the dimensionality of the data and Insider State clustering via Density-Based Spatial Clustering of Applications with Noise (IS-DBSCAN) (2) The EHI of multi-objective Bayesian optimization for optimizing the sensitive learning rate hyperparameter to ensure the stability of the Adabelief optimized WGAN and improve the quality of the generated adversarial samples. (3) The L2-SP regularization technique effectively fine-tunes the pretrained AGCN, which identifies the user behavioural pattern to detect the insiders. …”
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A STUDY TO ASSESS THE DISTRIBUTION OF SUSPECTED ADVERSE EVENTS FOLLOWING IMMUNISATION REPORTED IN A METROPOLITAN CITY IN INDIA by Sophie Simon, Shalini Rawat, Rohan Sangam, G D Velhal

“…Results: The AEFI reporting rate was calculated as 5.8 per 100000 doses administered per year. …”
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MODERN MOVEMENTS OF THE CRUST SURFACE IN GORNY ALTAI FROM GPS DATA by V. Yu. Timofeev, D. G. Ardyukov, A. V. Timofeev, E. V. Boiko

“…Analyzed are modern movements in the Gorny Altai region outside the Chuya earthquake area.The results of our study show that modern horizontal displacements occur in the NNW direction at the rate of 1.1 mm/yr, which is twice lower than the displacement rate before the earthquake.…”
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Study on influence of coal seam water content on effect of CO2 isobaric diffusion displacing CH4 by Liwei CHEN, Dongjie WANG, Le BIAN, Yuan LIU, Xiaohua LI

“…In the experiments of CH4 replacement by CO2 injection in coal with different water contents under isobaric diffusion conditions, it was found that, under the same water content conditions, with the increase of adsorption equilibrium pressure, the replacement amount and replacement rate of CH4 kept increasing, while the CO2 injection ratio kept decreasing, and the replacement effect of CH4 was better, while the utilization rate of CO2 was lower. …”
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Clinical Phenotypes of Hypoxia in Patients with COVID-19 by O. V. Voennov, A. V. Turentinov, K. V. Mokrov, P S. Zubееv, S. A. Abramov

“…Group 1 included patients without breathing difficulties who had respiratory rate up to 25 per minute. Group 2 patients had breathing difficulties and respiratory rate over 25 per minute.In addition to SpO2, severity of respiratory difficulties, respiratory rate (RR), forced breathing (FB), heart rate (HR), acid-base balance (ABB) and arterial and venous blood gases, capillary refill time, blood lactate level were assessed. …”
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Altered dynamic functional network connectivity in rheumatoid arthritis associated with peripheral inflammation and neuropsychiatric disorders by Lei Xie, Yanmin Zheng, Zhiduo Hou, Shuhua Ma, Zikai Huang, Jianhua Peng, Shuxin Huang, Ruiwei Guo, Jinzhuang Huang, Zhirong Lin, Zelin Zhuang, Jingjing Yin

“…The Spearman correlation was calculated between aberrant DFC alterations, Montreal Cognitive Assessment (MoCA), Hospital Anxiety and Depression Scale (HAD), C reactive protein (CRP) and erythrocyte sedimentation rate (ESR). Diagnostic efficacy of indicators was assessed using receiver operating characteristic analysis (ROC).Results Three dynamic functional states were identified. …”
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Early-stage endometrioid carcinoma with MSH6 protein deficiency: pitfalls in the diagnostic interpretation of microsatellite instability by Cheng Wang, Cheng Wang, Dongni Liang, Dongni Liang, Wei Wang, Wei Wang, Wei Kuang, Wei Kuang, Juan Zou, Juan Zou, Jing Zeng, Jing Zeng, Min Feng, Min Feng

“…This atypical MSI pattern is often overlooked, potentially increasing the risk of underdiagnosis of LS.…”
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Genetic External Characteristics of Tukong: Indonesian Rumpless Indigenous Chicken by Yuli Arif Tribudi, Veronica Margaretha Ani Nurgiartiningsih, Maria Ulfah, Aprilianna Putri Zahara Nafsina Luvita Sari, Dwi Nur Happy Hariyono, Pradita Iustitia Sitaresmi, Richard PMA Crooijmans, Muhammad Halim Natsir, Dwi Gusmalawati, Alek Ibrahim

“…The data were used to analyze the rate of the original gene, the frequency of autosomal genes, sex-linked genes, feather pattern, introgression rate, gene frequency, and expected heterozygosity. …”
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Site of Service Changes Have Resulted in Increased Opioid Prescriptions for Primary Total Hip and Knee Patients in Michigan, a Michigan Arthroplasty Registry Collaborative Quality... by Harjot Uppal, MD, David Markel, MD, Giresse Melone, MD, Simarjeet Puri, MD, Lisheng Chen, PhD, Tae Kim, MHSA, Brian Hallstrom, MD, Richard Hughes, PhD, Elizabeth Dailey, MD

“…ASCs had the lowest compliance rate for both THA (56%) and TKA(69%) compared to HOPDs (89%, 80%) and hospitals (83%, 87%) (P < .05), respectively. …”
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