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4261
Identification of galectin-9 and its antibacterial function in Yellow River carp (Cyprinus carpio haematopterus)
Published 2025-08-01“…IntroductionGalectin-9 is a β-galactoside-binding lectin that functions as a critical pattern recognition receptor (PRR) in the host immune system, initiating immune defense responses by recognizing and binding to pathogen-associated molecular patterns (PAMPs) on the surface of microorganisms. …”
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4262
Metal–organic nanostructures based on sono/chemo-nanodynamic synergy of TixOy/Ru reaction units: for ultrasound-induced dynamic cancer therapy
Published 2025-07-01“…Remarkably, ultrasound irradiation induced substantial oxidative stress and immunogenic cell death, promoting the release of damage-associated molecular patterns (DAMPs), which elevated the maturation rate of tumor-infiltrating dendritic cells (DCs) and significantly increased the proportion of CD8⁺ T cells. …”
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4263
Optimization of bovine oocyte cryopreservation: membrane fusion competence and cell death of linoleic acid-in vitro matured oocytes subjected to vitrification
Published 2025-07-01“…Zona pellucida-free oocytes co-incubated with sperm demonstrated that 43 μM LA better preserved the original sperm adhesion and fusion pattern post-vitrification, although fertilization rate was not improved. …”
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4264
Dynamic brain-heart-gut coupling during sleep: a continuous physiological signal analysis
Published 2025-05-01“…In terms of heart-gut coupling (HGC), the coupling strength between the very low frequency (VLF) band of heart rate variability (HRV) and all BS-derived power sequences was significantly lower than other HRV frequency bands. …”
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4265
Aberrant Histone Methylation in Patients with Graves’ Disease
Published 2019-01-01“…The rate (degree) of H3K4 and H3K9 methylation and the expressions of histone-modifying genes were investigated. …”
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4266
Neural signatures underlying the effect of social structure on empathy and altruistic behaviors
Published 2025-07-01“…Afterwards, participants rated the pain experienced by these innocents and shared money with other innocents. …”
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4267
Temperature-VPD-evapotranspiration interactions modulated asynchronous dynamics of vegetation photosynthesis and net ecosystem production in Eurasia
Published 2025-05-01“…The results showed that the rate of increase in NEP standardized anomalies (0.004 yr−1, p < 0.05) lagged behind NDVI/SIF/GPP standardized anomalies (0.009 − 0.014 yr−1, p < 0.01), particularly after 2000, and it was more pronounced in drylands. …”
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4268
A bibliometric analysis of research trends in mesenchymal stem cell therapy for neonatal bronchopulmonary dysplasia: 2004–2024
Published 2025-06-01“…Despite the growing body of preclinical evidence, visualization of publication patterns reveals significant gaps between laboratory findings and clinical applications, with only 8.2% of publications reporting clinical outcomes. …”
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4269
Dynamics of cerebral blood flow following sertraline treatment in adolescent depression
Published 2025-07-01“…Furthermore, Pearson correlation analysis was employed to examine associations between changes in regional CBF and clinical improvement, as measured by changes in the 17-item Hamilton Depression Rating Scale (HAMD-17) scores.ResultsAt baseline, adolescents with depression exhibited increased CBF in the posterior cuneus and decreased CBF in the middle temporal gyrus (MTG), right middle orbitofrontal gyrus, and the left middle frontal gyrus (MFG), compared to healthy controls. …”
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4270
Efficacy and Safety of Tofacitinib in Patients with Polymyalgia Rheumatica (EAST PMR): An open-label randomized controlled trial.
Published 2023-06-01“…Secondary endpoints: PMR-AS score, c-reactive protein (CRP), and erythrocyte sedimentation rate (ESR) at weeks 12 and 24. Thirty-nine patients with newly diagnosed PMR received tofacitinib, and 37 patients received glucocorticoid. …”
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4271
Estimation of duration and its changes in Lagrangian observations relying on ice floes in the Arctic Ocean utilizing a sea ice motion product
Published 2025-08-01“…Ice trajectory terminal points did not reveal an obvious long-term tendency, but they were regulated by large-scale atmospheric circulation patterns, especially those in the early drifting stage in autumn (OND). …”
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4272
Real-Time, Risk-Based Clinical Trial Quality Management in China: Development of a Digital Monitoring Platform
Published 2025-04-01“…Quality findings from the early-stage, interim-stage, and conclusion-stage QC rounds of clinical trials were rated by using 3 severity grades (minor, major, or critical) and classified into 5 categories (with 4 taxonomy levels under each category). …”
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4273
Loss of Reduction in Pediatric Distal Radius Fractures: Risk Factors From a Prospective Multicenter Registry
Published 2025-08-01“…On multivariate analysis, metaphyseal bicortical fracture pattern (OR = 2.3), prereduction translation of ≥51% (OR = 2.3), and nonanatomic closed reductions (OR = 1.9) independently increased the odds of LOR. …”
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4274
Criminal legal penalties, substance use, and overdose: a concept mapping study examining Colorado’s criminal legal penalties
Published 2025-01-01“…Participants — recruited from community-based organizations — identified, rated, sorted, and categorized factors affecting criminal legal involvement, substance use, and/or overdose in their community. …”
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4275
Analysis of influencing factors for primary membranous nephropathy complicated with atherosclerotic cardiovascular disease and establishment of a nomogram prediction model
Published 2025-03-01“…They also had significantly higher systolic blood pressure [130(120, 142) mmHg(1 mmHg=0.133 kPa) <italic>vs</italic> 122.0(113.5, 135.5) mmHg], higher diastolic blood pressure [80 (75, 90) mmHg <italic>vs</italic> 80(70, 85.5) mmHg], higher prevalence of hypertension[142(64.8%) <italic>vs</italic> 67 (32.7%)], and higher proportion of manual workers[60(27.4%) <italic>vs</italic> 28(13.7%)] Additionally, lymphocyte count (LYM), platelet count (PLT), blood sodium concentration (Na), blood urea nitrogen (BUN), blood creatinine (Cr), estimated glomerular filtration rate (eGFR), 24-hour quantitative urine protein, glutamic transaminase, urinary occult blood, number of urinary hyaline and pathological tubular patterns, C-reactive protein (CRP), complement C4, plasma fibrinogen, D-dimer, and centrocyte-lymphocyte ratio were all significantly different between the two groups (<italic>P</italic><0.05). …”
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4276
A data-driven approach to forest health assessment through multivariate analysis and machine learning techniques
Published 2025-07-01“…RF-based feature importance analysis showed tree DBH, height, regeneration rate, soil erosion, and tree density as key ecological drivers of forest health. …”
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4277
Digital learning resource use among Swedish medical students: insights from a nationwide survey
Published 2025-06-01“…Several background factors influence usage patterns. These data may support institutions, program directors and teachers in their efforts to guide and improve use of digital learning tools in medical schools.…”
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4278
Citronella oil-loaded electro-spun single and core-shell nano fibers as sustained repellent systems against Aedes aegypti
Published 2025-01-01“…It was found that maintaining the outer:inner flow rate ratio at 5:2 in coaxial process is imperative to produce good fibers. …”
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4279
Functioning in patients with major depression treated with duloxetine or a selective serotonin reuptake inhibitor in East Asia
Published 2016-02-01“…Depression severity was assessed using the 16-item Quick Inventory of Depressive Symptomatology-Self Report. PPS were rated using the modified Somatic Symptom Inventory. …”
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4280
Spatio-temporal mapping reveals changes in soil organic carbon stocks across the contiguous United States since 1955
Published 2025-08-01“…Abstract Understanding spatio-temporal patterns of soil organic carbon (SOC) is critical for global climate change mitigation and sustainable soil management. …”
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