Conversational AI agent for precision oncology: AI-HOPE-WNT integrates clinical and genomic data to investigate WNT pathway dysregulation in colorectal cancer by Ei-Wen Yang, Brigette Waldrup, Enrique Velazquez-Villarreal, Enrique Velazquez-Villarreal

“…Exploratory queries further assessed treatment response, co-mutation patterns, and population-specific trends.ResultsIn recapitulation analyses, AI-HOPE-WNT reproduced key trends from prior work, including improved survival in WNT-altered EOCRC and higher RNF43 mutation rates in Hispanic/Latino (H/L) populations compared to non-Hispanic White (NHW) people. …”
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Estimating the burden of disease attributable to non-assisted suicide in Switzerland from 2009 to 2021: a secondary data analysis by Annora Mack, Sarah Rajkumar, Jacob Kofler, Kaspar Wyss

“…The stark sex disparity in suicide rates further underscores the need for sex-sensitive approaches. …”
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Heterogeneity of Candida bloodstream isolates in an academic medical center and affiliated hospitals by Nancy E. Scott, Elizabeth Wash, Christopher Zajac, Serin E. Erayil, Susan E. Kline, Anna Selmecki

“…Phenotypic data, including patterns of antifungal drug resistance, are limited. …”
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Gut–Vaginal Microbiome Crosstalk in Ovarian Cancer: Implications for Early Diagnosis by Hao Lin, Zhen Zeng, Hong Zhang, Yongbin Jia, Jiangmei Pang, Jingjing Chen, Hu Zhang

“…Ovarian cancer remains a formidable global health burden, characterized by frequent late-stage diagnosis and elevated mortality rates attributable to its elusive pathogenesis and the critical lack of reliable early-detection biomarkers. …”
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Optical and photoluminescence characteristics of Pr3+-doped P2O5 +BaO+La2O3 glasses by C.R. Kesavulu, Ch. Basavapoornima, Pikkili Ramprasad, C.J. Deviprasad, Shobha Rani Depuru, C.K. Jayasankar

“…A luminescence peak at 600 nm was used as a monitoring level, and a 445 nm excitation was used to assess the decay curves. The decay rates exhibit a bi-exponential pattern, meaning that as the concentration of Pr3+ ions increase, the lifetimes become shorter. …”
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Numerical Study on the Influence of Inlet Blockage Ratios and Flow Conditions on Scour Development in Circular Culverts by Salam Hussein Sulaiman, Kaywan Othman Ahmed, Mohsen Isari, Jamil Bahrami

“…Each hydrograph included seven different flow discharges, and steady flow tests were conducted at the maximum rates observed during the unsteady scenarios. This study examined circular culverts subjected to inlet blockages of 0%, 25%, and 50% and compared the numerical result from Flow-3D simulations utilizing the Renormalization Group (RNG) turbulence model with observed data. …”
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Use of complementary medicine and uptake of COVID-19 vaccination among US adults by Holger Cramer, Holger Cramer, Mirela Bilc, Mirela Bilc

“…However, vaccination uptake was lower for both COVID-19 and flu vaccines, respectively, in individuals who visited chiropractors (AOR = 0.78, 95% CI [0.69, 0.89], p < 0.001; AOR = 0.71, 95% CI [0.63, 0.81], p < 0.001) and naturopaths (AOR = 0.66, 95% CI [0.51, 0.86], p = 0.002; AOR = 0.72, 95% CI [0.55, 0.94], p = 0.017). Uptake rates for both COVID-19 and flu vaccines were higher among individuals who visited an acupuncturist (COVID-19: AOR = 1.46, 95% CI [1.15, 1.86], p = 0.002; flu: AOR = 1.32, 95% CI [1.08, 1.63], p = 0.008). …”
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The association between cognitive ability and body mass index: A sibling-comparison analysis in four longitudinal studies. by Liam Wright, Neil M Davies, David Bann

“…<h4>Background</h4>Body mass index (BMI) and obesity rates have increased sharply since the 1980s. While multiple epidemiologic studies have found that higher adolescent cognitive ability is associated with lower adult BMI, residual and unobserved confounding due to family background may explain these associations. …”
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Impact of LDL-C levels on severity and outcome of intracranial haemorrhage: a single-centre retrospective study by Kang-Po Lee, Li-Chi Hsu

“…Moreover, statin use is associated with better long-term outcome and may attenuate the effects of initial LDL-C in ICH patients.Conclusions In patients with ICH, particularly those with deep ICH, lower LDL-C levels are associated with more severe ICH and higher short-term and long-term mortality rates. Further randomised controlled trials are warranted to determine the optimal LDL-C levels in patients with ICH and dyslipidaemia.…”
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A Global Systematic Review and Meta‐Analysis of Methods Used to Evaluate Predation and Diet of Domestic Cats (Felis catus) by Hannah L. Lockwood, Maren Huck

“…Palatability and detectability of prey appear to influence the data reported, and these aspects should be considered when calculating total predation rates.…”
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The Use of Sound Recorders to Remotely Measure Grass Intake Behaviour in Horses by Daisy E. F. Taylor, Bryony E. Lancaster, Andrea D. Ellis

“…Grazing was identified audibly (SR_ear) and visually through soundwave pattern software (SR_wav). Chew rates (SR_ear: 47 ± 5 chews/min, VD: 43 ± 4 chews/min) were similar between methods. …”
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Integrated evaluation and optimization of acid fracturing effectiveness in carbonate reservoirs: Experimental insights and field validation. by Peng Lu, Songlei Li, Jinsong Liu, Nan Yuan, Heng Liu

“…Implementation of the proposed methodology has increased stimulation success rates from 55% to 82% in pilot fields, with sustained production gains exceeding 35%. …”
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Surveillance of Multidrug-Resistant Genes in Clinically Significant Gram-Negative Bacteria Isolated from Hospital Wastewater by Shriya C. Shetty, Lakshya S. Gowda, Ankeeta Menona Jacob, Kalidas Shetty, A. Veena Shetty

“…PCR confirmed the presence of drug-resistance genes in Gram-negative bacterial isolates. Results: High rates of <i>Enterobacterales</i> resistant to carbapenems and cephalosporins observed in isolates from final treated effluent. …”
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The magnitude and time course of pre-saccadic foveal prediction depend on the conspicuity of the saccade target by Lisa M Kroell, Martin Rolfs

“…Foveal enhancement defined as the difference between hit rates to target-congruent and target-incongruent foveal probes increased with target opacity. …”
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Cognitive processing of Chinese verbal irony: the role of reverse adjacency relations in reaction time and accuracy by Mian Huang, Zijian Li, Yu Zheng, Caini Yang

“…Results revealed statistically significant difference across conditions, for experimental ironic sentences (6,012 ms) compared to control (4,901 ms) and baseline sentences (3,987 ms all p &lt; 0.001). Accuracy rates followed a similar pattern, with the experimental condition (64.1%) lower than the control (73.6%) and baseline (82.3%, all p &lt; 0.01). …”
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A Detailed Analysis of the Milky Way Warp Based on Classical Cepheids by Xiaoyue Zhou, Xiaodian Chen, Licai Deng, Shu Wang, Jiyu Wang, Jianxing Zhang

“…We analyze the impact of the adopted solar vertical velocity on the inferred warp precession rate and confirm the reliability of the measured precession rate. …”
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Demonstration of Scully–Drühl-type quantum erasers on quantum computers by Bo-Hung Chen, Dah-Wei Chiou, Hsiu-Chuan Hsu

“…On the IBM Quantum platform, delay gates can be employed to further defer the random choice, thereby amplifying the retrocausal effect. …”
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Multiple sclerosis mortality trends in Spain from 1981 to 2020 by L. Cayuela, A. de Albóniga-Chindurza, S. Gómez Enjuto, J. Lapeña-Motilva, S. Sainz de la Maza, A. González García, A. Cayuela

“…Age-standardised mortality rates (ASMR) and trend analysis were performed using joinpoint regression software. …”
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Release Behavior and Bioaccumulation Characteristics of Organophosphate Esters from Plastics in Marine Aquaculture by Zhi YANG, Dongni LIU, Shengnan HUANG, Xuetian DAI, Wei QIAN, Xiaoshan ZHU

“…Chlorinated OPEs exhibited the highest dissolution rates, with TCEP showing a dissolution rate of 40.6%. …”
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Epigenetic Alterations in Ovarian Function and Their Impact on Assisted Reproductive Technologies: A Systematic Review by Charalampos Voros, Antonia Varthaliti, Despoina Mavrogianni, Diamantis Athanasiou, Antonia Athanasiou, Aikaterini Athanasiou, Anthi-Maria Papahliou, Constantinos G. Zografos, Vasileios Topalis, Panagiota Kondili, Menelaos Darlas, Sophia Sina, Maria Anastasia Daskalaki, Marianna Theodora, Panos Antsaklis, Georgios Daskalakis

“…This systematic review investigates the significance of epigenetic pathways in ovarian function, with an emphasis on their effect on ART success rates. <b>Methods</b>: A thorough search of the PubMed, Scopus, and EMBASE databases was performed to find articles published between 2015 and 2024 that investigated the connection between epigenetic changes and ovarian function in ART patients. …”
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