Treatment Patterns, Adverse Events, and Clinical Outcomes with Steroidal Mineralocorticoid Receptor Antagonists: A Retrospective Analysis of Administrative Claims Data (RELICS) by Richard EL, Desai NR, Willey VJ, Gay A, Scott C, Folkerts K, Pessina E, Singh R, Teng CC, Oberprieler NG

“…Patients with a higher comorbidity burden, such as those with both CKD and T2D rather than CKD alone, experienced worse outcomes.Conclusion: High rates of treatment discontinuation and subsequent restart were observed across all subgroups, implying fluctuating sMRA use. …”
Get full text

Expression pattern changes of three homeologs in chemokine activity enhance antiviral response to herpesvirus infection in a newly synthesized alloheptaploid by Xiao-Li Yang, Yang Wang, Zhi Li, Qiao-Hong Lin, Peng Yu, Meng Lu, Xi-Yin Li, Zhong-Wei Wang, Xiao-Juan Zhang, Jian-Fang Gui, Li Zhou

“…However, our understanding about the patterns that allopolyploids modify homeolog expression upon pathogen invasion remains limited. …”
Get full text

Urban Recreational Space Heat-Emotion Distribution and Matching Pattern Based on Machine Learning: A Case Study of Guangzhou City by Wang Fuyuan, Zhang Zhiyu, Xie Yuanjing, Yang Xinyi, Sun Miao

“…Spatially, this disconnect can be categorized into three distinct types: the "polarized" pattern in the central city, the "experience enhancement" pattern in the Huadu, Panyu, Baiyun, and Conghua Districts, and the "insufficient supply" pattern in the Zengcheng, Huangpu, and Nansha Districts. …”
Get full text

A retrospective study of the antimicrobial susceptibility patterns of Klebsiella pneumoniae isolated from urine samples over a decade in South India by Mahadevaiah Neelambike Sumana, Yogeesh D. Maheshwarappa, Kalyani G., Kalyani G., Rashmi P. Mahale, Sowmya G. S, Morubagal Raghavendra Rao, Ranjitha Shankaregowda, Vidyavathi B. Chitaragi, Deepashree R., Sujatha S. R., Neetha S. Murthy, Badveti Satyasai, Vasimalli Vinay Kumar, Supreeta R. Shettar

“…Of the 920 K. pneumoniae isolates, 385 (41.84%) were carbapenem-resistant (CRKP). Isolation rates were higher in males (n = 229, 59.48%) than females (n = 156, 40.52%), with a statistically significant p-value (<0.0001). …”
Get full text

Regional patterns of genetic variants in expanded carrier screening: a next-generation sequencing pilot study in Fujian Province, China by Danhua Guo, Danhua Guo, Nani Zhou, Qianqian He, Qianqian He, Na Lin, Na Lin, Shuqiong He, Shuqiong He, Deqin He, Deqin He, Yifang Dai, Yifang Dai, Ying Li, Ying Li, Xuemei Chen, Xuemei Chen, Hailong Huang, Hailong Huang, Jia Jia, Hua Cao, Liangpu Xu, Liangpu Xu

“…The cumulative carrier rate for 28 genes was ≥1/100. Recurrent variants in GAA, GALT, CYP1B1, and MEFV were identified, exhibiting distinct regional patterns compared to previously reported variants in the Han Chinese population.ConclusionNGS-based ECS demonstrates significant potential for assessing the genetic burden of AR/XLR conditions and identifying ARCs in Fujian Province. …”
Get full text

The expanded inframammary fold triangle: Improved results in large volume breast reductions by Karan Chopra, Kashyap Komarraju Tadisina, Alexandra Conde-Green, Devinder P Singh

“…However, complication rates in super obese patients or patients receiving large volume reductions are high, ranging from 35 to 78%. …”
Get full text

Antimicrobial Resistance Patterns and Serological Diversity of <i>Shigella</i> Species from Patient Isolates at University Teaching Hospital in Lusaka, Zambia by Mike Nundwe, Joseph Yamweka Chizimu, John Mwaba, Misheck Shawa, Rodrick S. Katete, Mable Mwale Mutengo, Ruth Nakazwe, Namwiinga R. Mulunda, Cephas Sialubanje, Mox Malama Kalumbi, Yamba Kaunda, Rapheal Chanda, Herman Chambaro, Harvey K. Kamboyi, Thoko Kapalamula, Steward Mudenda, Freeman W. Chabala, Bernard M. Hang’ombe, Roma Chilengi, Chie Nakajima, Yasuhiko Suzuki

Get full text

Patterns of Opportunistic Infections and Antiretroviral Therapy Efficacy in Newly Diagnosed Human Immunodeficiency Virus-1 Patients: A Descriptive Study in India by N Kisenjang, Sumit Arora, Pooja Sangwan, Imam D Khan, Charu Mohan, Anmol Sharma, Vikram Sharma, Ankit Rao, Aditya Puniyani, Shivani Sangwan, Alisha Sharma, Swati Jain, Anuradha Makkar, Preeti Badhan, H Vanalahruaii

Get full text

Dynamic Lactate Clearance Patterns During Normothermic Machine Perfusion Predict Posttransplant Biliary Complications in Donation After Circulatory Death Liver Transplantation by Ayato Obana, MD, Miho Akabane, MD, Hannah Chi, MD, Nolan Ladd, MD, Andrew Nguyen, BA, Lin Abigail Tan, BS, Rithin Punjala, MBBS, Kejal Shah, MD, Matthew Hamilton, DO, Ashley Limkemann, MD, MPH, Navdeep Singh, MBBS, Musab Alebrahim, MD, Khalid Mumtaz, MBBS, Austin Schenk, MD, PhD, Sylvester Black, MD, PhD, Kenneth Washburn, MD

“…Among DBD grafts, no intercluster differences in PTBC rates were found. Conclusions. Dynamic lactate clearance patterns during NMP predict PTBCs in DCD LT. …”
Get full text

Prevalence of bacterial eye infections and multidrug resistance patterns among eye infection suspected patients in Ethiopia: a systematic review and meta-analysis by Mihret Tilahun, Alemu Gedefie, Bekele Sharew, Habtu Debash, Agumas Shibabaw

“…The pooled prevalence of MDR was 66.06%, with the highest rates in Somali (87.7%) and the lowest in Tigray (37.9%). …”
Get full text

Epidemiological perspectives of amyloidosis in Argentina: a cohort study analysing incidence and mortality patterns among a population affiliated to a medical care programme by María Lourdes Posadas-Martínez, Delfina Cirelli, Florencia De Florio, María Adela Aguirre, Elsa Mercedes Nucifora, Patricia Beatriz Sorroche, María Soledad Sáez, Valeria Inés Aliperti, Jimena Vicens, Marcelina Carretero

Get full text

Symptom Network Analysis and Unsupervised Clustering of Oncology Patients Identifies Drivers of Symptom Burden and Patient Subgroups With Distinct Symptom Patterns by Brandon H. Bergsneider, Terri S. Armstrong, Yvette P. Conley, Bruce Cooper, Marilyn Hammer, Jon D. Levine, Steven Paul, Christine Miaskowski, Orieta Celiku

“…In this study, computational approaches were used to unbiasedly characterize the heterogeneity of the symptom experience of oncology patients to elucidate symptom patterns and drivers of symptom burden. Methods Severity ratings for 32 symptoms on the Memorial Symptom Assessment Scale from 3088 oncology patients were analyzed. …”
Get full text

Incidence, Pattern and Mortality of Traumatic Abdominal Injury, a Three‐Year Study at the Largest Trauma Center in Southern Iran: A Cross‐Sectional Study by Mahnaz Yadollahi, Hosein Fazeli, Mehdi Ghasemian, Mohammad Reza Yousefi, Mehrdad Karajizadeh, Hanie Farajpour

Get full text

Treatment patterns and clinical outcomes of patients with HER2-positive T1micN0 breast cancer: a single-center analysis by Celine Yeh, Rachel Han, Abha Kulkarni, Charlie White, Yuan Chen, Matthew G. Hanna, Edi Brogi, Andrew D. Seidman

Get full text

Impact of the COVID-19 Pandemic on Buckle Fracture Treatment by Mehmet E. Kilinc, BS, Evan P. Sandefur, BS, Mosufa Zainab, BS, Nicholas J. Peterman, MD, Andrea A. Yu-Shan, MSHS, Peter J. Apel, MD, PhD

“…During peak COVID-19 era, adherence rates improved significantly to 41.18% (P < .001). …”
Get full text

DETERMINANTS OF HOUSEHOLD DEBT-TO-GDP FINANCIAL STABILITY, AND ECONOMIC RESILIENCE. A CROSS-COUNTRY PANEL ANALYSIS (2000–2023) by Chidera Favour EBELE, Gideon IHUARULAM

Get full text

Epidemiological Trends and Drug Resistance Patterns of Carbapenem-Resistant Gram-Negative Bacteria: A Retrospective Study in a Tertiary Hospital in China (2019-2024) by Hou B, Niu X, Yu Q, Wang W

“…In 2021, notable shifts in hospital infection control concerning CR-GNB were observed, with a reduction of over 40% in CRAB infection rates and a decline of over 35% in CRPA infection rates. …”
Get full text

Real-World Treatment Patterns and Survival Outcomes of Patients with Relapsed/Refractory Multiple Myeloma Treated with a Selinexor-Containing Triplet-Based Regimen by Andrew Whiteley, Stephen C. Ijioma, David Ray, Spencer S. Langerman, Ellen Hu, Amy Pierre, Tomer Mark, Habte Yimer

“…Previous clinical trials have demonstrated high rates of durable responses in the treatment of patients with triple-class-exposed RRMM with regimens containing selinexor, a first-in-class, orally available selective exportin 1 inhibitor. …”
Get full text

Spatial Patterns of Land Take in a Mediterranean City: An Assessment of the SDG Indicator 11.3.1 in the Peri-Urban Area of Thessaloniki by Athena Yiannakou, George Zografos

“…Using the rapidly suburbanized southern peri-urban area of Thessaloniki, Greece, as a case study, the paper analyzes the factors influencing the land cover change in the middle-class-led peri-urbanization during the period 2000–2018 and provides an estimate of the SDG indicator 11.3.1 “ratio of land consumption rate to population growth rate”, a suitable indicator for monitoring spatial changes. …”
Get full text

Knowledge, attitudes, and practices of rational drug prescribing in Nigerian Navy by Ahmadu Shehu Mohammed, Babatunde Enitan Ogunnowo, Odekunle Bola Odegbemi

Get full text