Speciation of Clinically Significant Coagulase Negative Staphylococci Isolates from Clinical Samples and their Susceptibility Pattern: A Cross-sectional Study from Western Uttar Pr... by Priya, Ismat Rehana, Anita Pandey, Rajesh Kumar Shah, Jitendra Kumar Chaudhary

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Patterns of Treatment and Real‐World Outcomes of Patients With Non‐small Cell Lung Cancer With EGFR Exon 20 Insertion Mutations Receiving Mobocertinib: The EXTRACT Study by Geoffrey Liu, Shi Feng Nyaw, Tony S. K. Mok, Hubert Curcio, Alexis B. Cortot, Tsz Yeung Kam, Renaud Descourt, Yin Kwan Chik, Parneet Cheema, James M. Gwinnutt, Eric N. Churchill, Justin Nyborn, Eileen Curran, Alexandra Savell, Yu Yin, Katie Chong, Yuka Tanaka‐Chambers, Julian Kretz, Jacques Cadranel

“…The median real‐world progression‐free survival (PFS) on mobocertinib was 4.76 months (95% CI: 3.98, 6.21). The overall response rate and disease control rate were 20.0% and 48.6%, respectively (median duration of response: 8.34 months [95% CI: 3.61, 9.49]). …”
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Cerebrospinal fluid data compilation and knowledge-based interpretation of bacterial, viral, parasitic, oncological, chronic inflammatory and demyelinating diseases. Diagnostic pat... by Hansotto Reiber

“…ABSTRACT The analysis of intrathecal IgG, IgA and IgM synthesis in cerebrospinal fluid (CSF) and evaluation in combined quotient diagrams provides disease-related patterns. The compilation with complementary parameters (barrier function, i.e., CSF flow rate, cytology, lactate, antibodies) in a cumulative CSF data report allows a knowledge-based interpretation and provides analytical and medical plausibility for the quality assessment in CSF laboratories. …”
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Nationwide real-world practice pattern and clinical data of palbociclib in HR (+), HER2 (−) metastatic breast cancer patients in Korea (KCSG BR21-15) by Jieun Lee, Dae-Won Lee, Min Hwan Kim, Jee Hung Kim, Ju Won Kim, Jae-Ho Byun, Kyoung Eun Lee, Myoung Joo Kang, Su-Jin Koh, Soojung Hong, Hye Sung Won, Han Jo Kim, In Hae Park, Seong Hoon Shin, Sun Kyung Baek, Seul-Gi Kim, Sung Ae Koh, Joo Young Jung, Ji-Yeon Kim, Gun Min Kim, Kabsoo Shin, In Sook Woo, Hyun Seon Kim, Seock-Ah Im, Yeon Hee Park

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Alternate row mulching optimizes soil temperature and water conditions and improves wheat yield in dryland farming by Qiu-yan YAN, Fei DONG, Ge LOU, Feng YANG, Jin-xiu LU, Feng LI, Jian-cheng ZHANG, Jun-hui LI, Zeng-qiang DUAN

“…Warming effect of soil temperature under the HM pattern persisted longer than under the FM model with the same mulching rates. …”
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Bacteriological evaluation, antibiogram, and phenotypic detection of MBL-producing gram-negative bacteria isolated from outdoor patients with otorrhea attending Ayub medical Comple... by Najeeb B., Shakeela Q., Qureshi S.A.

“…The current study aimed to study the patients to assess the occurrence rate, susceptibility pattern, and prevalence rate of metallo beta-lactamase (MBL) producing gram-negative bacteria to prevent the prevalent strains and direct the physicians to appropriate antibiotic therapy. …”
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Fellowship training in microvascular surgery and post-fellowship practice patterns: a cross sectional survey of microvascular surgeons from facial plastic and reconstructive surger... by Douglas M. Bennion, Peter T. Dziegielewski, Brian J. Boyce, Yadro Ducic, Raja Sawhney

“…Results Among survey respondents (n = 21, 22% response rate), two-thirds completed 20–100 microvascular cases during fellowship using mainly radial forearm, fibula, anterior lateral thigh, latissimus and rectus free tissue transfers. …”
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Prevalence, Antimicrobial Susceptibility Pattern, and Associated Factors of Urinary Tract Infections among Adult Diabetic Patients at Metu Karl Heinz Referral Hospital, Southwest E... by Tesfaye Gutema, Fitsum Weldegebreal, Dadi Marami, Zelalem Teklemariam

“…The escalating antimicrobial resistance rate among bacteria over the past years is another concern in the treatment of urinary tract infections. …”
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Prevalence, antimicrobial resistance patterns, and associated factors of Staphylococcus aureus among different clinical specimens in Wad Medani, Sudan: a four-year, laboratory-base... by Yousif B. Hamadalneel, Marwa F. Alamin, Hifa O. Ahmed, Safa F. Eltoum, Elmuntasir Elamin

“…The overall S. aureus isolation rate was 39.1% (697/1784). The strains were primarily isolated from female patients (79.5%, 554/697), 38.9% of whom (271/697) were aged 30–44 years. …”
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Evaluating antibiotic use patterns and compliance in Shanxi province hospitals: a 7-year retrospective study of national clinical improvement system data (2015–2021) by Rui Zhang, Song Wang, Shuyun Wang, Jian Ren, Zhihong Ren, Yang Tang, Donghong Yin, Shucheng Yang, Ruigang Hou, Jinju Duan

“…The proportion of patients undergoing clean surgical procedures with prophylactic antibiotic prescriptions decreased from 45.08% to 40.0% between 2019 and 2021, with a compound annual growth rate (CAGR) of −5.80 (p=0.103). The intensity of antibiotic treatment among inpatients was from 42.00 to 39.70 daily defined dose between 2017 and 2021, with a CAGR of −1.40 (p=0.015). …”
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Configuration and Dynamic Analysis of Complex Docking Test Platform by ZHANG Yuan, FAN Chang-zhen

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Large language models' knowledge of children's memory and suggestibility: Evaluating model predictions of prior experimental results by Pekka Santtila, Yongjie Sun, Kristjan Kask, Liisa Järvilehto, Jiaxing Xiu

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Investigation of three alternative histopathological scoring methods at the invasive tumour front in colorectal cancer by Walaiphorn Woraharn, Ashley McCulloch, Christopher Bigley, Phimmada Hatthakarnkul, Kathryn Pennel, Peter Alexander, Hester vanWyk, Antonia Roseweir, Jennifer Hay, Noori Maka, James Park, Nigel B Jamieson, Joanne Edwards, Campbell SD Roxburgh

“…High scores with the Karamitopoulou and Taskin methods correlated significantly with adverse prognostic factors, particularly advanced T stage (p < 0.001), N stage (p < 0.001), and the presence of peritoneal involvement (p < 0.001). The survival rate of the TGP method demonstrated that patients with an infiltrative growth pattern had significantly worse CRC survival compared to those with pushing and intermediate growth patterns (p < 0.001) and the TGP method retained its independence as a prognostic factor in multivariable Cox regression analysis only for colon cancer‐specific survival (p < 0.001). …”
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Survival benefit from adjuvant chemoradiotherapy in local advanced gastric cancer without accurate D2 confirmation: a real-world retrospective study (TJ-ARK01) by Xiao-Xiao Luo, Ben Zhao, Li Sun, Yu-Hong Dai, Hong Qiu, Xiang-Lin Yuan

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Wire Arc Additive Manufacturing of Aluminium 5356 Alloy: Process Parameter Optimization and Structure-Property Analysis by K. Saravanakumar, J. Nampoothiri, M.R. Prat heesh Kumar

“…Wire Arc Additive Manufacturing (WAAM) is an emerging technology in the manufacturing sector, offering benefits such as increased production rates and cost efficiency. This study investigates the WAAM of aluminium alloy 5356, deposited on aluminium 6082 base plates. …”
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Post-caesarean section infection burden, antimicrobial resistance pattern, and associated factors at all Africa Leprosy Rehabilitation and Training Center Comprehensive Specialized... by Namuna Ali, Sebsib Neway, Kassu Desta

“…In sub-Saharan Africa, the incidence is 7.3%, while Ethiopia reports rates as high as 10.4%. Risk factors include older age, prolonged hospitalization, and emergency surgeries, with common pathogens being S. aureus and E. coli. …”
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Genome-wide identification and function analysis of the sucrose phosphate synthase MdSPS gene family in apple by Li-hua ZHANG, Ling-cheng ZHU, Yu XU, Long LÜ, Xing-guo LI, Wen-hui LI, Wan-da LIU, Feng-wang MA, Ming-jun LI, De-guo HAN

“…Sucrose phosphate synthase (SPS) is a rate-limiting enzyme that works in conjunction with sucrose-6-phosphate phosphatase (SPP) for sucrose synthesis, and it plays an essential role in energy provisioning during growth and development in plants as well as improving fruit quality. …”
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Machine Learning-Based Classification of Programming Logic Understanding Levels by Mouse-Tracking Heatmaps by Attaporn Khaesawad, Yosuke Fukuchi, Vibol Yem, Nobuyuki Nishiuchi

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Pattern of disease and predictors of mortality among critically ill geriatric patients admitted to intensive care unit at a teaching hospital in Ethiopia: a retrospective cohort st... by Amanuel Sisay Endeshaw, Sitotaw Tesfa Zegeye, Meseret Hulualem Nega, Simachew Amogne Debas, Mulat Mossie Derseh

“…The incidence rate of mortality was 6.3 deaths per 100 person-days observation. …”
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Drug utilization pattern and cost analysis of antidiabetic drugs among type 2 diabetic patients at a teaching hospital in South India: A prospective observational study by Sekar Kavitha, Anandabaskar Nishanthi, Vivekraj Navabalan, Shanthi Manickam, Anuranjani Dhamodharan, Girija Subramanian

“…Conclusion: This study highlights areas for improvement, including the use of multiple medications, a relatively high rate of injectable prescriptions, and opportunities to enhance generic prescribing among diabetic patients in a teaching hospital in India. …”
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