Body mass change over winter is consistently sex-specific across roe deer (Capreolus capreolus) populations by Hewison, A.J. Mark, Bonnot, Nadège C., Gaillard, Jean-Michel, Kjellander, Petter, Lemaitre, Jean-François, Morellet, Nicolas, Pellerin, Maryline

“…We suggest that allocation to antler growth and territory establishment drives this pattern, providing a likely explanation to account for the lower rates of male adult survival that are consistently reported in this weakly dimorphic species.…”
Get full text

Experimental Investigation on Energy Dissipation in Diversion Tunnel at the Head of Canal by ZHONG Kun, YAN Fu-gen, GUO Jian-hua, YI Shun, LI Min-kang

“…Then, based on the hydraulic model test results under different conditions, the downstream flow pressure characteristics, cavitation characteristics of the weir surface behind the operating gate, pressure characteristics of the gradually expanding stilling basin floor and sidewalls, flow connection patterns, and energy dissipation performance were obtained. …”
Get full text

Planned Liver Stereotactic Body Radiotherapy for Residual Colorectal Cancer Liver Metastases After Surgery: A Single-Arm Retrospective Study by Sixuan Li, Dezuo Dong, Xuan Zheng, Hongzhi Wang, Kun Wang, Baocai Xing, Weihu Wang

“…The 1-, and 2-year cumulative incidence rates of LF after SBRT were 7.7%, and 9.6%, respectively. …”
Get full text

Relevance of Cellular Homeostasis-Related Gene Expression Signatures in Distinct Molecular Subtypes of Breast Cancer by Sharda P. Singh, Chathurika S. Dhanasekara, Michael W. Melkus, Chhanda Bose, Sonia Y. Khan, Flavia Sardela de Miranda, Maria F. Mahecha, Prrishti J. Gukhool, Sahil S. Tonk, Se-Ran Jun, Sahra Uygun, Rakhshanda Layeequr Rahman

“…Demographic factors such as age, race/ethnicity, menopausal status, and body mass index have been correlated with variations in incidence, mortality, and survival rates. Over the past decade, comprehensive genomic profiling has been widely used to identify molecular biomarkers and signatures to develop novel therapeutic strategies for patients. …”
Get full text

Multi-omics derivation of a core gene signature for predicting therapeutic response and characterizing immune dysregulation in inflammatory bowel disease by Mingming Wang, Liping Liang, Zibo Tang, Jimin Han, Lele Wu, Le Liu, Le Liu, Ye Chen, Ye Chen

“…Nomogram-based risk stratification effectively predicted biologic treatment responses across multiple therapeutic classes using four independent treatment datasets (GSE16879, GSE92415, GSE73661, GSE206285): low-risk patients demonstrated superior response rates to golimumab (63.3%), infliximab (54.8%), and vedolizumab (29% vs. 15% in high-risk group). …”
Get full text

Clinical features of patients with dysthymia in a large cohort of Han Chinese women with recurrent major depression. by Wenqing Wu, Zhoubing Wang, Yan Wei, Guanghua Zhang, Shenxun Shi, Jingfang Gao, Youhui Li, Ming Tao, Kerang Zhang, Xumei Wang, Chengge Gao, Lijun Yang, Kan Li, Jianguo Shi, Gang Wang, Lanfen Liu, Jinbei Zhang, Bo Du, Guoqing Jiang, Jianhua Shen, Ying Liu, Wei Liang, Jing Sun, Jian Hu, Tiebang Liu, Xueyi Wang, Guodong Miao, Huaqing Meng, Yi Li, Chunmei Hu, Yi Li, Guoping Huang, Gongying Li, Baowei Ha, Hong Deng, Qiyi Mei, Hui Zhong, Shugui Gao, Hong Sang, Yutang Zhang, Xiang Fang, Fengyu Yu, Donglin Yang, Tieqiao Liu, Yunchun Chen, Xiaohong Hong, Wenyuan Wu, Guibing Chen, Min Cai, Yan Song, Jiyang Pan, Jicheng Dong, Runde Pan, Wei Zhang, Zhenming Shen, Zhengrong Liu, Danhua Gu, Xiaoping Wang, Xiaojuan Liu, Qiwen Zhang, Yihan Li, Yiping Chen, Kenneth S Kendler, Jonathan Flint, Zhen Zhang

“…<h4>Conclusions</h4>There are increased rates of stressful life events in MDD with dysthymia, but the impact of life events on susceptibility to dysthymia with MDD differs from that seen for MDD alone. …”
Get full text

Toxicokinetics, tissue distribution, and toxic potency of PFOS alternative OBS in adult zebrafish (Danio rerio) based on flow-through exposure system by Yilong Zou, Yu Zhou, Xianglian Wang, Guiqing Gao, Gang Chen, Zhanmeng Liu, Mi Deng, Xueping Huang, Yongming Wu

“…Our findings indicate that OBS accumulated rapidly in zebrafish, with log kinetic bioconcentration factor (logBCFk) values ranging from 2.48 to 2.70 and slow elimination rates (ke = 0.0490–0.0643 d−1). The blood, liver, and muscle were responsible for over 50 % of the total body burden of OBS, with tissue concentrations decreasing in the following order: blood > liver > intestine > gills > gonad > brain > muscle, suggesting a tissue-specific accumulation pattern. …”
Get full text

Dysregulated neural coding in the vagus nerve during long sepsis by Joshua J. Strohl, Tomás S. Huerta, Sergio Robbiati, Patricio T. Huerta

“…We found that LS mice exhibited significantly higher baseline vagal activity compared to controls, with elevated firing rates during both respiratory bursts and inter-burst intervals. …”
Get full text

The system of atmosphere, land, ice and ocean in the region near the 79N Glacier in northeast Greenland: synthesis and key findings from the Greenland Ice Sheet–Ocean Interaction (... by T. Kanzow, T. Kanzow, A. Humbert, A. Humbert, T. Mölg, M. Scheinert, M. Braun, H. Burchard, F. Doglioni, P. Hochreuther, M. Horwath, O. Huhn, M. Kappelsberger, J. Kusche, E. Loebel, K. Lutz, B. Marzeion, B. Marzeion, R. McPherson, M. Mohammadi-Aragh, M. Mohammadi-Aragh, M. Möller, M. Möller, C. Pickler, M. Reinert, M. Rhein, M. Rhein, M. Rückamp, M. Rückamp, J. Schaffer, J. Schaffer, M. Shafeeque, M. Shafeeque, S. Stolzenberger, R. Timmermann, J. Turton, J. Turton, C. Wekerle, O. Zeising

“…Observations and models employed in this study are consistent in terms of melt rates occurring below the floating ice tongue. Our results suggest that the multidecadal warming of Atlantic Intermediate Water flowing into the cavity below the ice tongue – supplied by the recirculating branch of the West Spitsbergen Current in Fram Strait – is the main driver of the recent major increase in basal melt rates. …”
Get full text

A Comprehensive Analysis of the Radiographic Characteristics and Bilateral Symmetry of the Mental Foramen by Radhwan Algabri, Faisal Abulohoom, Abdelrahman Fadag, Hesham Al‐Sharani, Sami Al‐Aqab, Nassr Al‐Hutbany, Emad Alryashi, Ahmed Keshk, Ahmed Yaseen Alqutaibi

“…Gender differences were significant for the shape of the MF and the pattern of the canal on the right side. The symmetry rates for various features included horizontal positions (87.4%), vertical positions (82.6%), and shapes (80.4%). …”
Get full text

Negative Regulation of <i>GmNAC35</i> by miR164 Enhances Drought Tolerance in Soybean by Wentao Hu, Man Zhang, Jie Lu, Miaomiao Zhang, Reqing He, Youlin Zhu, Dong Wang, Liyun Jiang

“…Conversely, <i>GmNAC35</i> showed an inverse pattern, indicating negative regulation by miR164. …”
Get full text

An integrated high-resolution bathymetric model for the Danube Delta system by L. Alaerts, L. Alaerts, J. Lambrechts, N. R. Randresihaja, N. R. Randresihaja, L. Vandenbulcke, O. Gourgue, E. Hanert, E. Hanert, M. Grégoire

“…These error rates are comparable to those observed in bathymetry interpolation in rivers with similar source datasets. …”
Get full text

Biomechanical evaluation of novel construct for stabilizing subcapital femoral neck fractures: a synthetic bone model by Anjan R. Shah, Miguel A. Diaz, Douglas L. Cerynik, Blake Schultz

“…Abstract Background High complication rates continue to be reported for femoral neck fractures, where moderate to severe shortening has been associated with pain and inferior functional outcomes. …”
Get full text

Preoperative Bowel Preparation in Minimally Invasive and Vaginal Gynecologic Surgery by Michail Diakosavvas, Nikolaos Thomakos, Alexandros Psarris, Zacharias Fasoulakis, Marianna Theodora, Dimitrios Haidopoulos, Alexandros Rodolakis

“…Taking into consideration the fact that in most gynecologic cases there is minimal probability of bowel intraluminal entry and, thus, low surgical site infection rates, most scientific societies have issued guidelines against the use of any bowel preparation regimen before laparoscopic or vaginal surgery. …”
Get full text

Copper and Temperature Interactions Induce Differential Physiological and Metal Exclusion Responses in the Model Brown Macroalga <i>Ectocarpus</i> by Alex Santillán-Sarmiento, Paula S. M. Celis-Plá, A. John Moody, Claudio A. Saez, Murray T. Brown

“…In this study, we exposed the model brown seaweed <i>Ectocarpus</i> to different Cu concentrations (0, 0.8, 1.6, and 3.2 μM) at two different temperatures (15 and 25 °C). Relative growth rates decreased at 25 °C for the two highest Cu concentrations after 8 days of exposure, but a contrasting pattern was observed in the photosynthetic maximum quantum yield (<i>F_v</i>/<i>F_m</i>) and photosynthetic efficiency (<i>α</i>), where reductions were observed at 15 °C for the same Cu concentrations. …”
Get full text

Systemic Immunomodulatory Therapy in Uveitis Related to Beh&amp;ccedil;et&amp;rsquo;s Disease: A 10-year Profile by Almeida M, Ferreira AM, Araújo JR, Figueira L

“…The median treatment duration was 63.5 months, significantly reducing relapse rates from 2 ± 2.0 to 1 ± 1.2 per year (p &lt; 0.001). …”
Get full text

Accelerometer-measured physical activity, frailty, and all-cause mortality and life expectancy among middle-aged and older adults: a UK Biobank longitudinal study by Yang Yang, Liangkai Chen, Filippos T. Filippidis

“…Abstract Background Physical activity (PA) is associated with reduced frailty and lower mortality rates among middle-aged and older adults. However, the extent to which total PA volume and specific PA intensities are associated with mortality risk across frailty status remains unclear. …”
Get full text

Antimicrobial Resistance Profile and Biofilm Formation of <i>Listeria monocytogenes</i> Isolated from Meat by Joana Paiva, Vanessa Silva, Patrícia Poeta, Cristina Saraiva

“…Introduction: <i>Listeria monocytogenes</i> is the causative agent of listeriosis, a serious infectious disease with one of the highest case fatality rates among foodborne diseases affecting humans. …”
Get full text

Treatment for Paget’s disease: surgical approaches by E. Yu. Fetisova, A. D. Zikiryakhodzhaev, N. N. Volchenko

“…Breast cancer (BC) ranks first in the pattern of female malignancies (20.7 %) and remains the top cancer among women. …”
Get full text

Socioeconomic inequalities in non-communicable diseases prevalence in India: disparities between self-reported diagnoses and standardized measures. by Sukumar Vellakkal, Sukumar Vellakkal, S V Subramanian, Christopher Millett, Sanjay Basu, David Stuckler, Shah Ebrahim

“…<h4>Methods</h4>We calculated age-adjusted prevalence rates of common NCDs from the Study on Global Ageing and Adult Health, a nationally representative cross-sectional survey. …”
Get full text