Burden and Outcomes of Severe Lower Respiratory Tract Infections with Unknown Etiology: A Retrospective Observational Study on Epidemiological Trends Over an 8-Year Period (2016–20... by Giovanni Scaglione, Marta Canuti, Martina Offer, Valentina Breschi, Antonio Piralla, Fausto Baldanti, Gabriele Del Castillo, Francesco Scovenna, Sabrina Buoro, Federica Morani, Danilo Cereda, Alessandra Bandera, Andrea Gori, Marta Colaneri

“…Results Among 683,741 hospitalizations, 338,211 (49.5%) were of unknown etiology, showing a 12.3% intra-hospital mortality rate (41,627 deaths) and 4.0% intensive care unit admission rate (13,625 admissions). …”
Get full text

Multiple Respiratory Virus Detection in Acute Respiratory Infection Patients in Mie Prefecture, Japan, 2021–2023 by Yuriko Tomita, Hiyori Okura, Rika Mochizuki, Manami Negoro, Takuya Yano, Yusuke Kobayashi, Ikuyo Takayama, Kiyosu Taniguchi, Shinji Watanabe, Hideki Hasegawa

“…The Coronavirus disease 2019 (COVID-19) pandemic significantly impacted the circulation patterns of respiratory viruses worldwide. To better understand viral circulation patterns during the transition from pandemic to endemic phase, we conducted comprehensive respiratory virus surveillance in Mie Prefecture, Japan, during 2021–2023, coinciding with the Delta-to-Omicron transition of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). …”
Get full text

Two-step skeletization of binary images based on the Zhang-Suen model and the producing mask by J., Ma, V. Yu. Tsviatkou, V. K. Kanapelka

“…The aim of the work is to limit excessive thinning and increase the resistance to contour noise of skeletons resulted from arbitrary binary image shape while maintaining a high skeletonization rate. The skeleton is a set of thin lines, the relative position, the size and shape, which conveys information of size, shape and orientation in space of the corresponding homogeneous region of the image. …”
Get full text

Revisiting biomarker discovery by plasma proteomics by Philipp E Geyer, Lesca M Holdt, Daniel Teupser, Matthias Mann

“…However, existing biomarkers are far from comprehensive and often lack specificity and new ones are being developed at a very slow rate. As described in this review, mass spectrometry (MS)‐based proteomics has become a powerful technology in biological research and it is now poised to allow the characterization of the plasma proteome in great depth. …”
Get full text

Estimating the Impact of Technical Barriers to Trade in WTO Regime: The Case of Pakistan by Amir Mustafa, Ihtsham Ul Haq Padda, Sadia Safdar

“…The findings depict that GDP of Pakistan and partners, exchange rate, tariff, distance, and contiguity are vital factors; along with TBT cases initiated by Pakistan have also impacted import from WTO members. …”
Get full text

Eye Detection using Helmholtz Principle by Ahmed et al.

“…Eye Detection is used in many applications like pattern recognition, biometric, surveillance system and many other systems. …”
Get full text

NEW POSSIBILITIES OF RADIOLOGIC DIAGNOSTICS OF BREAST CANCER by A. B. Abduraimov, S. K. Ternovoy

“…Early breast cancer diagnosis is contemporary and actual problem due to the increase of breast cancer incidence and low detection rate of the disease.Multispiral computed tomography of mammary gland with intravenous contrast agent injection allows resolving diagnostic tasks aris- ing in patients with high density mammary gland tissue, considerable edema, fibrosis, postoperative conditions. …”
Get full text

LEFT VENTRICULAR WALL THICKNESS AND AUTONOMIC REGULATION IN PATIENTS WITH HYPERTROPHIC CARDIOMYOPATHY by O. Allaberganov, T. A. Abdullaev, G. A. Nagaeva

“…In addition, Group II patients demonstrated autonomic disbalance, sympathetic hyperactivity, and disturbed circadian patterns of heart rate.…”
Get full text

The Convallis rule for unsupervised learning in cortical networks. by Pierre Yger, Kenneth D Harris

“…Implementation of the rule caused a recurrent cortex-like network of simulated spiking neurons to develop rate representations of real-world speech stimuli, enabling classification by a downstream linear decoder. …”
Get full text

Integration of chromosome conformation and gene expression networks reveals regulatory mechanisms in triple negative breast cancer by Helena Reyes-Gopar, Helena Reyes-Gopar, Helena Reyes-Gopar, Keila Adonai Pérez-Fuentes, Matthew L. Bendall, Enrique Hernández-Lemus, Enrique Hernández-Lemus

“…IntroductionTriple-negative breast cancer (TNBC) accounts for twelve percent of all breast cancer cases, with a survival rate around ten percent lower than ER+/PR+ positive breast cancers. …”
Get full text

Radiocleavable rare-earth nanoactivators targeting over-expressed folate receptors induce mitochondrial dysfunction and remodel immune suppressive microenvironment in pancreatic ca... by Tanvi Gupta, Shang-Rung Wu, Li-Chan Chang, Forn-Chia Lin, Yan-Shen Shan, Chen-Sheng Yeh, Wen-Pin Su

“…Abstract Pancreatic cancer is a fatal cancer with poor prognosis and survival rate, often diagnosed usually in the advanced stage of disease. …”
Get full text

Reinforcement Learning-Based Generative Security Framework for Host Intrusion Detection by Yongsik Kim, Su-Youn Hong, Sungjin Park, Huy Kang Kim

“…The proposed framework demonstrated a high accuracy rate of 96.5% average when faced with different attacks. …”
Get full text

EMOTIVE SPEECH ACTS IN CROSS-CULTURAL COMMUNICATION: A COMPREHENSIVE ANALYSIS AND EXPERIMENTAL STUDY by Kenul E. Abdurehmanova

“…The research confirms that certain aspects of emotional expression — such as increased vocal intensity for anger and decreased speech rate for sadness — remain relatively consistent across language groups, supporting the universality hypothesis. …”
Get full text

Altruism Enhances Frontal Alpha Asymmetry and Reduces Sympathetic Activity: A Multimodal EEG‐ECG Study With Implications for Therapeutic Interventions by Junya Orui, Keigo Shiraiwa, Takao Inoue, Masaya Ueda, Keita Ueno, Yasuo Naito, Ryouhei Ishii

“…Parasympathetic activity negatively correlated with temporal‐gamma connectivity (p = 0.002), and heart rate change negatively correlated with temporal‐prefrontal theta connectivity (p = 0.048). …”
Get full text

Spatial disparities of population aging in Shenzhen: from China’s Hukou perspective by Qing Luo, Zhuoying Li, Yuanjun Li, Yunhao Yang, Jiaxin Liu, Guangbo Liu, Huayi Wu

“…Although its overall aging rate remains below the international aging society threshold, the city confronts unique challenges as a migrant receiving metropolis without domestic precedents. …”
Get full text

Geomorphic index alterations and socioeconomic implications: A case study of a Coastal River system in Bangladesh by Sukhen Goswami, Md. Masum Billah, Md Sabbir Hossen, Mehedi Hasan Ovi, Shacin Chandra Saha, Mir Md. Tasnim Alam, Probir Kumar Bhowmik, Atikul Haque Farazi, Md. Ashraful Islam, Dhiman Kumer Roy

“…Mid-channel bar formation, absent before 2000, reached 4.0 km2 by 2023, affecting flow patterns. The widening rate shifted from a maximum of 19 m/year (1980–2000, pre-sand mining) to 27 m/year (2000–2023, post-sand mining), with a peak near Doarika Bridge, which increased the vulnerability of the Barishal Airport area, averaging 3.65 m/year. …”
Get full text

Machine learning and microfluidic integration for oocyte quality prediction by Hassan Saffari, Davood Fathi, Peyman Palay, Hamid Gourabi, Rouhollah Fathi

“…Additionally, oocyte diameter and the critical flow rate (Q)—defined as the minimum flow rate necessary for an oocyte to pass through the channel—were included as predictive variables. …”
Get full text

Impact of Sodium Ion Stress on the Mechanism of Lead Ion Migration in Electrochemical Treatment of Lead-Contaminated Soil by Yinyin Zhang, Jiangtao Han, Libin Zang

“…This study specifically validates the migration patterns of lead ions under sodium ion stress in soil and concludes that a high concentration of sodium ions, when coexisting with lead ions, diminishes the migration rate of lead ions, consequently reducing the removal efficiency of lead ions. 1. …”
Get full text

Combining Autoregressive Models and Phonological Knowledge Bases for Improved Accuracy in Korean Grapheme-to-Phoneme Conversion by Sung-Ki Choi, Hyuk-Chul Kwon, Minho Kim

“…Experimental results show that a BiLSTM-LSTM AR model based on ELECTRA embeddings achieves a phoneme error rate (PER) of 0.2%, word error rate (WER) of 0.68%, and a sentence accuracy of 95.16%, outperforming both a traditional rule-based approach (24.51% sentence accuracy) and non-autoregressive variants implemented on the same dataset (achieving 81.32%–85.72% sentence accuracy). …”
Get full text

¹³C metabolic flux analysis identifies an unusual route for pyruvate dissimilation in mycobacteria which requires isocitrate lyase and carbon dioxide fixation. by Dany J V Beste, Bhushan Bonde, Nathaniel Hawkins, Jane L Ward, Michael H Beale, Stephan Noack, Katharina Nöh, Nicholas J Kruger, R George Ratcliffe, Johnjoe McFadden

“…Here we show that deletion of one of the two icl genes impairs the replication of Mycobacterium bovis BCG at slow growth rate in a carbon limited chemostat. In order to further understand the role of isocitrate lyase in the central metabolism of mycobacteria the effect of growth rate on the in vivo fluxes was studied for the first time using ¹³C-metabolic flux analysis (MFA). …”
Get full text