Efficacy of switching from originator adalimumab to biosimilar adalimumab-AACF in patients with axial spondyloarthritis: a 12-month observational study by Fanny Alcira Reyes Neira, Barbara Bayeh, Karina Rossi Bonfiglioli, Nadia Emi Aikawa, Ana Paula Luppino Assad, Renata Miossi, Fernando Henrique Carlos de Souza, Carlos Emilio Insfrán, Henrique Ayres Mayrink Giardini, Emily Figueiredo Vieira Neves Yuki, Eloisa Bonfa, Carla Gonçalves Schahin Saad, Ana Cristina de Medeiros-Ribeiro, Julio Cesar Bertacini de Moraes, Andrea Yukie Shimabuco

“…Ankylosing Spondylitis Disease Activity Score (ASDAS)-CRP remained stable when comparing T0 to T6 [1.56 (± 0.88) vs. 1.50 (± 0.82), P = 0.73] and T12 [1.56 (± 0.88) vs. 1.26 (± 0.86), P = 0.13]. A similar pattern was observed for ASDAS-erythrocyte sedimentation rate (ESR; P > 0.05) and Bath Ankylosing Spondylitis Disease Activity Index (BASDAI; P > 0.05). …”
Get full text

Sociodemographic and regional differences in neonatal and infant mortality in Switzerland in 2011–2018: the Swiss National Cohort by Veronika W. Skrivankova, Leonie D. Schreck, Claudia Berlin, Radoslaw Panczak, Kaspar Staub, Marcel Zwahlen, Sven M. Schulzke, Matthias Egger, Claudia E. Kuehni

“… BACKGROUND AND AIMS: Despite a well-funded healthcare system with universal insurance coverage, Switzerland has one of the highest neonatal and infant mortality rates among high-income countries. Identifying avoidable risk factors targeted by evidence-based policies is a public health priority. …”
Get full text

Long-term growth and risk factors for crankshaft phenomenon following posterior hemivertebra resection with mono-segment fusion in congenital early-onset scoliosis by Zhiming Peng, Yiwei Zhao, You Du, Haoran Zhang, Shengru Wang, Jianguo Zhang

“…Although VBH, IPL, and VBAP increased significantly in all vertebrae (p < 0.05), there were no significant differences between the crankshaft and non‑crankshaft groups in terms of final follow‑up values, absolute growth, or growth rate. Multivariate analysis identified incomplete hemivertebra resection as the predominant risk factor (OR = 18.85, 95% CI: 2.65–251.66, p = 0.002). …”
Get full text

Influence of precipitation and runoff on human-induced land subsidence in the Yellow River Delta by Yaoshen Fan, Guangzhou Wang, Shentang Dou, Chao Jiang, Hongyu Ji, Shenliang Chen, Xiaokang Du, Shoubing Yu, Yan Wu, Shaohua Zhang

“…The study reveals pronounced seasonal variations in land subsidence across the YRD, with subsidence rates in summer being substantially lower than those in spring, autumn, and winter. …”
Get full text

The impact of referral workload on cardiology registrars in a high-volume district general hospital: implications for workforce well-being and service efficiency by Md Imran Hossain, Jaymin Shantilal Shah

“…A structured survey was distributed to 12 cardiology registrars, achieving a 92% response rate, assessing workload perception, stress, exhaustion, bleep volume impact, consultant support and training limitations. …”
Get full text

Sex disparities in alcohol-associated liver disease and subtype differences in alcohol-attributable cancers in the United States by Pojsakorn Danpanichkul, Yanfang Pang, Tanuj Mahendru, Primrose Tothanarungroj, Luis Antonio Díaz, Juan Pablo Arab, Pimtawan Jatupornpakdee, Mark D. Muthiah, Kwanjit Duangsonk, Won-Mook Choi, Daniel Q. Huang, Donghee Kim, Mazen Noureddin, Karn Wijarnpreecha, Suthat Liangpunsakul, Amit G. Singal, Ju Dong Yang

“…The age-standardized incidence and death rate of ALD rose disproportionately among females compared to males. …”
Get full text

Impact of Revised Vaccination Recommendations for Mature Infants on Premature Infants’ Vaccination Compliance in Germany by Felicitas Kühne, Christof von Eiff, Julia Schiffner-Rohe, Lina Döring, Kathrin Gerchow, Karolin Seidel, Maren Laurenz

“…Results After the change in STIKO recommendations in 2020, the full HEXA vaccination rate for premature infants decreased significantly to 57.8% (2018, 71.0%), while it increased to 81.3% (2018, 73.8%) for mature infants. …”
Get full text

Antibacterial therapy for Lyme disease in children by S.O. Nykytyuk, S.S. Levenets, T.V. Hariyan, I.P. Mironets, A.S. Sverstiuk

“…The incidence rate in Ternopil region significantly exceeds the national average — 28.7 versus 13.25 per 100,000 population. …”
Get full text

RETRACTED ARTICLE: Interleukin-27 ameliorates coxsackievirus-B3-induced viral myocarditis by inhibiting Th17 cells by Hengshan Zhu, Chuang Lou, Ping Liu

“…However, the expression pattern and functional role of IL-27 in viral myocarditis (VMC) has not been investigated. …”
Get full text

Sexually transmitted infections among patients attending the General Practice Clinic, Wesley Guild Hospital, Ilesa, Nigeria by S.S. Olakolu, E.A. Abioye Kuteyi, O.O. Oyegbade

“…The median age at coitarche was 21 years while the median age at marriage was 25 years. The prevalence rates of current, past and lifetime STI were 18.8%, 22.4% and 32% respectively. …”
Get full text

A Novel Deployment Scheme Based on Three-Dimensional Coverage Model for Wireless Sensor Networks by Fu Xiao, Yang Yang, Ruchuan Wang, Lijuan Sun

“…Experimental results show that, compared with traditional random method, sensor nodes number is reduced effectively while coverage rate of monitor area is ensured using our coverage pattern and deterministic deployment scheme.…”
Get full text

Accounting for temporal and spatial autocorrelation to examine the effects of climate change on vegetation greenness trend in China by Lingwei Chen, Likai Zhu, Cuiyutong Yang, Zizhen Dong, Rui Huang, Jijun Meng, Min Liu

“…The common practice to detect and explain greenness pattern from remote sensing time series is mostly based on pixel-by-pixel analysis, which often fails to account for spatial autocorrelation and may lead to spurious patterns. …”
Get full text

Driving Forces and Future Scenario Simulation of Urban Agglomeration Expansion in China: A Case Study of the Pearl River Delta Urban Agglomeration by Zeduo Zou, Xiuyan Zhao, Shuyuan Liu, Chunshan Zhou

“…The results indicate the following: (1) During 1990–2020, urban expansion in the Pearl River Delta urban agglomeration exhibited a “stepwise growth” pattern, with an annual expansion rate of 3.7%. Regional land use remained dominated by forest (accounting for over 50%), while construction land surged from 6.5% to 21.8% of total land cover. …”
Get full text

Dietary intake and five types of mental disorders: a bidirectional Mendelian randomization study by Yichun Zhang, Mingzhu Zhang, Qihua Guan, Pengcheng Liu, Wangxin Zhang, Song Yang, Hualei Dong, Haifeng Hou

“…Outcomes were reported as odds ratios (OR) and regression coefficients (β), which were adjusted by False Discovery Rate (FDR) corrections. Results Forward MR analyses revealed that genetically predicted high-fat and high-protein intakes were related to an increased risk of anxiety [fat: OR = 3.103, 95% confidence interval (CI): 1.015 to 9.486, P IVW = 0.047, FDR = 0.209; protein: OR = 3.364, 95% CI: 1.071 to 10.567, P IVW = 0.038, FDR = 0.189]. …”
Get full text

Increasing population growth by asymmetric segregation of a limiting resource during cell division by Nurit Avraham, Ilya Soifer, Miri Carmi, Naama Barkai

“…Abstract We report that when budding yeast are transferred to low‐metal environment, they adopt a proliferation pattern in which division is restricted to the subpopulation of mother cells which were born in rich conditions, before the shift. …”
Get full text

Bifurcation analysis of multistability and hysteresis in a model of HIV infection by I. V. Mironov, M. Yu. Khristichenk, Yu. M. Nechepurenko, D. S. Grebennikov, G. A. Bocharov

“…The macrophage activation rate constant is considered as a bifurcation parameter. …”
Get full text

Nosological aspects of hepatomegaly and splenomegaly at pediatric age by M. M. Kotovich, F. K. Manerov, E. V. Luchsheva

“…Frequency of hepatomegaly and/or splenomegaly of unspecified etiology was analyzed with correlation to outpatient clinic admission rate and results of routine inspections. Results. …”
Get full text

TUBERCULOSIS IN CHILDREN IN THE RUSSIAN FEDERATION AT THE PRESENT STAGE by A. V. Mordyk, E. A. Tsygankova, L. V. Puzyryova, A. A. Turitsa

“…The literature review presents data on peculiarities of tuberculosis epidemiology, incidence rate and clinical pattern in children in the Russian Federation. …”
Get full text

Alfvén Wave Propagation in the Io Plasma Torus by P. C. Hinton, F. Bagenal, B. Bonfond

“…Abstract Io, the most volcanically active body in the solar system, fuels a plasma torus around Jupiter with dissociation products of SO2 at a rate of ~1,000 kg/s. We use a combination of in situ Voyager 1 data and Cassini Ultraviolet Imaging Spectrograph observations to constrain a diffusive equilibrium model of the Io plasma torus. …”
Get full text

Transient Analysis of a k-out-of-n:G System with N-Policy, Repairmen’s Multiple Vacations, and Redundant Dependency by Wenqing Wu, Yinghui Tang

“…Under such assumptions, the availability, the rate of occurrence of failures, and the reliability of the system are derived in transient regime by applying the quasi-birth-and-death process. …”
Get full text