Long-term real-world outcomes of first-line immunotherapy in non-small cell lung cancer – a population-based cohort study in Sweden by Gunnar Wagenius, Anders Vikström, Anders Berglund, Stina Salomonsson, Goran Bencina, Xiaohan Hu, Diana Chirovsky, Hans Brunnström

“…Interpretation: Real-world OS in Swedish patients receiving first-line PD-(L)1 inhibitor-based regimens was consistent with that observed in clinical trials. Moderate OS rates were observed in PS2, with limited sample sizes. …”
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Opportunities for immunocorrection aiming for reduction of morbidity in the areas with adverse occupational and environmental conditions by S. V. Petlenko, E. G. Golovacheva, O. I. Afanasieva

“…The one-year follow-up showed high effectiveness of these drugs, as shown by decreased incidence of acute infectious and lower exacerbation rates of chronic respiratory and gastrointestinal diseases. …”
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Determinants of chronic disease patients' intention to use Internet diagnosis and treatment services: based on the UTAUT2 model by Jing Zhao, Bei Li, Jianwei Sun, Xu Zeng, Jing Zheng

“…Furthermore, based on the interactive mechanisms among these factors, targeted policy recommendations are advanced to enhance service utilization rates and optimize the quality of Internet diagnosis and treatment services.MethodsGuided by the theoretical framework, and informed by expert consultations and a preliminary survey, the questionnaire was meticulously designed and refined. …”
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Organisation of physical education in universities for students with disabilities: Modular approach by L. V. Zakharova, O. N. Moskovchenko, U. Solimene, N. V. Tretyakova, N. V. Bannikova, N. V. Lyulina, O. A. Kattsin

“…The evaluation of the validity of differences in the average values of the studied indicators was performed according to Student’s t-test at a significance level of 5%. The growth rates of indicators were calculated according to Brody’s formula.Results and scientific novelty. …”
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Fungi present distinguishable isotopic signals in their lipids when grown on glycolytic versus tricarboxylic acid cycle intermediates by S. Jabinski, S. Jabinski, V. Kučera, V. Kučera, M. Kopáček, M. Kopáček, J. Jansa, T. B. Meador, T. B. Meador, T. B. Meador

“…<p>Microbial activity in soils controls both the size and turnover rates of large carbon (<span class="inline-formula">C</span>) inventories stored in the subsurface, having important consequences for partitioning of <span class="inline-formula">C</span> between terrestrial and atmospheric reservoirs as well as recycling of mineral nutrients such as nitrogen or phosphorus (often bound to the <span class="inline-formula">C</span>) that support plant growth. …”
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Advance, steadfast, retreat? Growth and establishment of white spruce seedlings at treelines in Alaska by Andreas Burger, Mario Trouillier, Martin Wilmking

“…In contrast, high seedling densities and growth rates at the cold treeline and cold forest indicate favorable conditions for seedling establishment and densification. …”
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Clinical, epidemiological, and virological features of Mpox in Beijing, China – May 31–June 21, 2023 by Xiangfeng Dou, Fu Li, Zhenyong Ren, Daitao Zhang, Jia Li, Dan Li, Yulan Sun, Haoyuan Jin, Renqing Li, Weihong Li, Xin Zhang, Yang Yang, Lei Jia, Yu Han, Wai Li, Yang Pan, Wenjie Tan, Peng Yang, Quanyi Wang

“…There were high oropharyngeal swab (75.8%) and blood (84.6%) positivity rates. All MPXV strains belonged to the B.1.3 branch of the West African lineage. …”
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A low-cost mitigation system for ammonia removal from broiler house exhaust air by Jingjing Luo, Jinsheng Rong, Shizhen Zhou, Haoliang Wang, Miao Li, Xiliang Yan, Yingbao Wu, Yan Wang

“…The results of the environmental simulation chamber show that 80 ppm hypochlorous acid and 70 ppm chlorine dioxide are cost-effective, achieving high ammonia (NH₃) removal rates. Field validation in a broiler house demonstrated that using 80 ppm hypochlorous acid with the ARBS achieved NH₃ and dust removal efficiencies of 82 % and 77 %, respectively. …”
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Infrared Compositional Measurements in Comet C/2017 K2 (Pan-STARRS) at Heliocentric Distances Beyond 2.3 au by Chemeda Ejeta, Erika Gibb, Michael A. DiSanti, Hideyo Kawakita, Boncho P. Bonev, Neil Dello Russo, Nathan X. Roth, Younas Khan, Adam J. McKay, Michael R. Combi, Lori Feaga, Mohammad Saki, Ronald J. Vervack Jr, Yinsi Shou

“…We report gas rotational temperatures ( T _rot ) and molecular production rates ( Q ; molecules per second) or upper limits for the “hypervolatile” species CH _4 , CO, and C _2 H _6 , together with less volatile ices (CH _3 OH, H _2 O, HCN, C _2 H _2 , NH _3 , and OCS) over a range of pre-perihelion distances, R _h = 3.15–2.35 au. …”
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Assessing the impact of AI tools on mobility and daily assistance for children with down syndrome in Saudi Arabia by Rayan Alanazi, Adel Sabre Alanazi, Sohil Alqazlan, Houcine Benlaria

“…Among AI users only, perceived effectiveness was rated moderately high for daily independence (M = 3.85, SD = 0.93) and mobility (M = 3.78, SD = 1.18). …”
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Short physical performance battery: Pilot study of a human motion capture app (MobiSPPB) by Lucas Küppers, Richard Pfannenstiel, Arezoo Bozorgmehr, Stephan Jonas, Birgitta Weltermann, Lara Marie Reimer

“…Two experienced raters rated the SPPB performance, and a smartphone recorded at the same time. …”
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Gut Microbiota and Lipid Metabolism in Bullfrog Tadpoles: A Comparative Study Across Nutritional Stages by Zhilong Wang, Pengxiang Liu, Jun Xie, Huirong Yang, Guangjun Wang, Kai Zhang, Rui Shu, Zhifei Li, Jingjing Tian, Hongyan Li, Wenping Xie, Wangbao Gong, Yun Xia

“…These insights provide a theoretical foundation for nutritional interventions aimed at enhancing tadpole growth and survival rates.…”
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A Case Study Analysis of Separation Anxiety in the Effect of the Maternal and Paternal Role on Separation Anxiety in Early Childhood by Elena Drazheva

“…The aim is to understand how different patterns of attachment and family dynamics influence the intensity of anxiety reactions. …”
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Bridging micro and macroevolution: insights from chromosomal dynamics in plants by Carmen Benítez-Benítez, Ashwini V. Mohan, Rogelio Sánchez-Villegas, Inés Gómez-Ramos, Ana Valdés-Florido, Kay Lucek, Marek Slovák, Marek Slovák, Filip Kolář, Filip Kolář, Ilia J. Leitch, Modesto Luceño, Isabel Larridon, Angelino Carta, Angelino Carta, Joan Cuscó-Borràs, Enrique Maguilla, Alegría Montero-Ramírez, Patrick G. Meirmans, Alison Dawn Scott, Santiago Martín-Bravo, Marcial Escudero

“…At the macroevolutionary level, we investigated the association between karyotype diversity and diversification rates using evidence from comparative genomics, chromosomal evolution modelling across phylogenies, and the association with several traits across different angiosperm lineages. …”
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Clear cell endometrial carcinoma: analysis of the results of a 20-year follow-up by K. P. Laktionov, G. M. Abdullayeva, O. A. Anurova, S. M. Gadzhiyeva

“…The paper presents data on the clinical and morphological characteristics, clinical presentation, and treatment of clear cell carcinoma, as well as survival rates in patients with this condition. It shows an association of the expression of the intercellular adhesion molecules E-cadhedrin, α- and β-catenins, the molecule of Her-2/neu with the clinical and morphological pattern of the disease, which has been determined by an immunohisto- chemical assay.…”
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Association of psychosocial factors and biological pathways identified from rare-variant analysis with longitudinal trajectories of treatment response in major depressive disorder by Haiping Tang, Yan Xia, Chenjie Gao, Yufan Cai, Yongqi Shao, Wenji Chen, Yonggui Yuan, Chunyu Liu, Zhijun Zhang, Zhi Xu

“…Treatment response trajectories were identified through cluster analysis using normalized score change ratios from the 17-item Hamilton Rating Scale for Depression (HAMD-17) at baseline and weeks 2, 4, 6, and 8. …”
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Characteristics of Anemia in Children Aged 6 Months to 5 Years Attending External Consultations at a Pediatric Hospital in Lisbon, Portugal by Réka Maulide Cane, Sérgio Chicumbe, Youssouf Keita, Anaxore Casimiro, Bárbara Martins Saraiva, Joana Vasconcelos, Beatriz Luzio Vaz, Afonso Sousa, Mafalda Cabral, Francisco Branco Caetano, Luís Varandas, Isabel Craveiro

“…Five children (6.8%) had normal hemoglobin but abnormal red-cell indices, with microcytic (60.0%; 3/5) or normocytic (40.0%; 2/5) patterns. Anemia rates were higher in males (55.1%), children aged 24–59 months, those residing in the Metropolitan Lisbon Area (82.6%), children whose caregivers had only basic or secondary education (58.0%), and those whose mothers were born in foreign countries (48.4%). …”
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Neurotoxoplasmosis and aids cerebrospinal, fluid analysis in 96 patients: estudo do líquido cefalorraqueano em 96 pacientes by L. R. Machado, J. A. Livramento, A. Spina -França

“…It is possible to conclude that patients with toxoplasmosis associated to AIDS exhibit CSF inflammatory pattern similar to patients with neurotoxoplasmosis without AIDS, except in respect to gamma globulin rates for which a cumulative effect can be detected.…”
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Neurobehavioral mechanisms of fear and anxiety in multiple sclerosis by Lil Meyer-Arndt, Rebekka Rust, Judith Bellmann-Strobl, Tanja Schmitz-Hübsch, Lajos Marko, Sofia Forslund, Michael Scheel, Stefan M. Gold, Stefan Hetzer, Friedemann Paul, Martin Weygandt

“…The fact that a machine learning model trained to associate fMRI fear response patterns with fear ratings in HPs predicts fear ratings from fMRI data across MS groups using an MVPA cross-decoding approach suggests that generic fear processing mechanisms substantially contribute to anxiety in MS.…”
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WGCNA-ML-MR integration: uncovering immune-related genes in prostate cancer by Jing Lv, Jing Lv, Yuhua Zhou, Yuhua Zhou, Shengkai Jin, Shengkai Jin, Chaowei Fu, Chaowei Fu, Yang Shen, Yang Shen, Bo Liu, Bo Liu, Menglu Li, Yuwei Zhang, Yuwei Zhang, Ninghan Feng, Ninghan Feng, Ninghan Feng

“…BackgroundProstate cancer is one of the most common tumors in men, with its incidence and mortality rates continuing to rise year by year. Prostate-specific antigen (PSA) is the most commonly used screening indicator, but its lack of specificity leads to overdiagnosis and overtreatment. …”
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