Statistics and behavior of clinically significant extra-pulmonary vein atrial fibrillation sources: machine-learning-enhanced electrographic flow mapping in persistent atrial fibri... by Peter Ruppersberg, Steven Castellano, Philip Haeusser, Kostiantyn Ahapov, Melissa H. Kong, Stefan G. Spitzer, Stefan G. Spitzer, Georg Nölker, Andreas Rillig, Tamas Szili-Torok

“…Our machine learning approach established an activity threshold, above which divergent wavefront patterns—termed “significant sources”—predicted AF recurrence. …”
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Can Fire Season Type Serve as a Critical Factor in Fire Regime Classification System in China? by Huijuan Li, Sumei Zhang, Xugang Lian, Yuan Zhang, Fengfeng Zhao

“…Fire regime (FR) is a key element in the study of ecosystem dynamics, supporting natural resource management planning by identifying gaps in fire patterns in time and space and planning to assess ecological conditions. …”
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Integrative single‐cell transcriptomic analysis deciphers heterogeneous characteristics of gastrointestinal tract cancer by Chuwen Sun, Tong Li, Xin Jin, Zhihui Xiu, Hang Su, Huanming Yang, Ming Liu, Kui Wu

“…Abstract Background Gastrointestinal tract cancer (GIC), including oesophageal cancer (EC), gastric cancer (GC) and colorectal cancer (CRC), is characterised with high global incidence and mortality rates, with similar tumourigenic processes. However, the common and heterogeneous molecular features among GIC at single‐cell level remain poorly characterised. …”
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Pitfalls in the diagnosis of apparent homozygous mutations: two cases of IL10RA deficiency inflammatory bowel disease and a literature review by Xiu Shi, Ziqing Ye, Lai Qian, Wenhui Hu, Ye Yang, Chunmeng He, Zhiheng Huang, Bingbing Wu, Ying Huang

“…Abstract Background In East Asia, IL10RA is the predominant pathogenic gene in patients with very early-onset inflammatory bowel disease (VEO-IBD), frequently characterised by refractory diarrhoea and severe perianal disease, resulting in elevated death rates. IL10RA-deficient IBD, an autosomal recessive genetic disorder, has been documented to be inherited through the conventional compound heterozygous or homozygous mutation patterns from both parents. …”
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Characterizing Breast Tumor Heterogeneity Through IVIM-DWI Parameters and Signal Decay Analysis by Si-Wa Chan, Chun-An Lin, Yen-Chieh Ouyang, Guan-Yuan Chen, Chein-I Chang, Chin-Yao Lin, Chih-Chiang Hung, Chih-Yean Lum, Kuo-Chung Wang, Ming-Cheng Liu

“…Evaluation using 3D-ROC analysis also indicated that the DNN was the best detector based on metrics like target detection rate and overall effectiveness. The DNN model further exhibited the capability to identify tumor heterogeneity, differentiating high- and low-cellularity regions. …”
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EFFECT OF NEURODEGENERATIVE CHANGES IN THE BRAIN ON THE FORMATION OF THE DISEASE CLINICAL PICTURE IN PATIENTS WITH MULTIPLE SCLEROSIS by L. N. Prakhova, Ye. P. Magonov, A. G. Ilves, A. A. Bogdan, G. V. Kataeva, Ye. S. Malakhova, Zh. I. Savintseva, I. D. Stolyarov, T. N. Trofimova

“…Neurodegenerative changes of brain structures evolve with different rates, have different intensity and determine the set of symptoms of neurological impairment and severity of disability, which indicates the presence of certain patterns of the process of atrophy in the brain, forming the clinical picture of the disease.…”
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Verification of a Probabilistic Model and Optimization in Long-Range Networks by José Luis Romero Vázquez, Abel García-Barrientos, José Alberto Del-Puerto-Flores, Francisco R. Castillo Soria, Roilhi F. Ibarra-Hernández, Ulises Pineda Rico, Ernesto Zambrano-Serrano

“…The proposed model integrates multiple critical factors, including packet arrival rates, transmission power levels, and the distance between transmitting nodes and the gateway. …”
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Comparative analysis of soil thermal conductivity in the permafrost regions of the Qinghai–Tibetan Plateau and the Arctic by Wenhao Liu, Ren Li, Tonghua Wu, Guojie Hu, Xiaodong Wu, Shenning Wang, Junjie Ma, Jianzong Shi, Shengfeng Tang, Xiaofan Zhu, Yongping Qiao

“…The mean STC values in the QTP permafrost region during the thawing period are significantly higher than those during the freezing period. (2) STC of the QTP exhibits a fluctuating pattern at different depths, in contrast, the average STC value in the Arctic increases steadily with depth, with an increase rate of approximately 0.005 Wm−1 K−1/cm. (3) The analysis of influencing factors revealed that although moisture content, bulk density, and porosity are the primary drivers of regional variations in STC between the QTP and the Arctic permafrost, moisture elements in the QTP region have a greater influence on STC and the effect is stronger with increasing depth and during the freeze–thaw cycles. …”
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Different molecular characteristics and antimicrobial resistance profiles of Clostridium difficile in the Asia-Pacific region by Yun Luo, Elaine Cheong, Qiao Bian, Deirdre A. Collins, Julian Ye, Jeong Hwan Shin, Wing Cheong Yam, Tohru Takata, Xiaojun Song, Xianjun Wang, Mini Kamboj, Thomas Gottlieb, Jianmin Jiang, Thomas V. Riley, Yi-Wei Tang, Dazhi Jin

“…Healthcare-associated (HA) CDI was mainly from older patients with more frequent antimicrobial use and higher A-B+ positive rates. Higher resistance to gatifloxacin, tetracycline, and erythromycin were observed in HA-CDI patients (χ2 = 4.76-7.89, p = 0.005-0.029). …”
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Antimicrobial susceptibility profiles of thermophilic Campylobacter species from human, pig, and chicken feces in Rwanda by Noel Gahamanyi, Noel Gahamanyi, Arsene Musana Habimana, Jean Paul Harerimana, Josiane Mukayisenga, Salomon Ntwali, Anathali Umuhoza, Emmanuel Nsengiyumva, Emmanuel Irimaso, Jean Bosco Shimirwa, Cheol-Ho Pan, Erick Vitus Komba, Claude Mambo Muvunyi, Nadine Rujeni, Raghavendra G. Amachawadi

“…Multi-drug resistance (MDR) was observed among the isolates, with the highest rates observed in chicken isolates (88.0%). Proportions of MDR among pig (40.9%) and human (40.7%) isolates were more or less similar. …”
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Cancelable Multi-Branch Deep Learning Framework for Privacy-Preserving ECG Biometric Authentication by Mohamed Hammad, Ali Abdullah S. AlQahtani, Mohammed ELAffendi, Abdelhamied A. Ateya, Nebojsa Bacanin

“…We evaluate the framework on two publicly available ECG datasets (PTB and ECG-ID) achieving high authentication performance with accuracies of 96.25% and 96.43%, respectively, and Equal Error Rates (EER) of 3.55% and 3.6%. The system meets critical privacy-preserving criteria, including irreversibility, unlinkability, diversity, and revocability. …”
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Evolutionary trajectory estimation via replication simulation of coronavirus spike gene based on random mutation and similarity-based selection by Min Chan Kim, Hye Ji Jung, Seong Sik Jang, Van Thi Lo, Hye Kwon Kim

“…Simulations tracking the evolution of SARS-CoV-2 Wuhan-Hu-1 toward the Omicron variant (BA.1) displayed plateau-like similarity trajectories, where increased substitution rates resulted in a more rapid attainment of the plateau stage. …”
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Insights from the Biorepository and Integrative Genomics pediatric resource by Silvia Buonaiuto, Franco Marsico, Akram Mohammed, Lokesh K. Chinthala, Ernestine K. Amos-Abanyie, Regeneron Genetics Center, Pjotr Prins, Khyobeni Mozhui, Robert J. Rooney, Robert W. Williams, Robert L. Davis, Terri H. Finkel, Chester W. Brown, Vincenza Colonna

“…We observe ancestry-specific rates of novel genetic variants, which are enriched for functional or clinical relevance. …”
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A neuronal imaging dataset for deep learning in the reconstruction of single-neuron axons by Liya Li, Liya Li, Ying Hu, Ying Hu, Xiaojun Wang, Pei Sun, Tingwei Quan

“…Our results demonstrate significantly improved axon detection rates across both state-of-the-art and traditional methodologies. …”
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Deep Learning Approach for Classifying DDoS Attack Traffic in SDN Environments by Mohd Nadeem, Shweta Dwivedi, Rizwan Akhtar, Shameem Ahmad Ansari, Saumya Singh, Eram Fatima Siddiqui, Rajeev Kumar

“…A neural network classifier analyzes this data to identify complex patterns and behaviors associated with DDoS attacks. …”
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Land Use Effects on the Space Use and Dispersal of an Apex Predator in an Ecotone Between Tropical Biodiversity Hotspots by Bernardo Brandão Niebuhr, Sandra M. C. Cavalcanti, Ermeson A. Vilalba, Vanessa V. Alberico, João Carlos Zecchini Gebin, Danilo da Costa Santos, Ananda de Barros Barban, Raphael de Oliveira, Eliezer Gurarie, Ronaldo G. Morato

“…In contrast, movement rates were higher in open pastures, mainly during dispersal. …”
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Effects of PBAT biodegradable mulch on lettuce (Lactuca sativa L.) physiology and soil microbial community: Based on a long-term degradation trial by Weichang Gao, Zugui Tu, Xie Yin, Shuang Ming, Kai Cai

“…The relative abundances of the bacterial genus Chujaibacter and Pseudolabrys increased with high PBAT application rates. Beneficial fungi such as Amphinema and Trichoderma showed an increasing trend, while pathogenic fungi exhibited the opposite pattern. …”
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The global burden of chronic kidney disease due to diabetes mellitus type 2 attributable to diet high in sugar-sweetened beverages among the elderly: a comprehensive analysis from... by Ben Hu, Ben Hu, Xiaohan Qiu, Zhengbiao Luo, Zhengbiao Luo, Jingxiong Chen, Jun Feng, Jun Feng, Linlin Hou, Linlin Hou

“…However, the global burden of CKD-T2DM attributable to high SSB consumption among elderly populations remains poorly characterized.MethodsUsing data from the Global Burden of Disease Study 2021, we examined age-standardized mortality rates (ASMR) and disability-adjusted life year rates (ASDR) of CKD-T2DM attributable to high SSB consumption among individuals aged 60 years and older across 204 countries and territories from 1990 to 2021. …”
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Association between ECG Abnormalities and Hookah and Cigarette Smoking in the MASHAD Cohort Study Subjects by Maryam Mohammadi-Bajgiran, Reyhaneh Saffar-Khorasani, Muhammad Islampanah, Reza Nejad Shahrokh Abadi, ‌Bahram Shahri, Sara Saffar Soflaei, Souren Nemati-Khorasani, Habibollah Esmaily, Gordon Ferns, Mohsen Moohebati, Majid Ghayour-Mobarhan

“…Cigarette users (92.3% male) had significantly lower BMI and higher employment rates compared to non-smokers, whereas hookah smokers (90.2% female) had higher BMIs and were predominantly retirees. …”
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Analysis of the International, Regional, and National Endocarditis-Related Disease Burdens (1990–2021), and Changes to Projections for the Next 15 Years: A Population-Based Study by Qiyuan Bai, Hao Chen, Hongxu Liu, Xuhua Li, Yang Chen, Dan Guo, Bing Song, Cuntao Yu

“…Clustering analysis results indicated a significant increase in the estimated annual percentage change (EAPC) of mortality and DALY rates for endocarditis in East Asia. A significant correlation exists between EAPC and the ASRs of disease burden. …”
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