Effect of Tadalafil on cardiac function and left ventricular dimensions in Duchenne muscular dystrophy: safety and cardiac MRI substudy results from a randomized, placebo-controlle... by David Cox, Barry Byrne, David W. Hammers, John Landry, H. Lee Sweeney

“…Ejection fraction (EF), fractional shortening, and M-mode ventricular dimensions were measured on echocardiograms. 12-lead ECGs were centrally evaluated for heart rate and intervals, and qualitative diagnoses. Vital signs and unsolicited adverse events were collected throughout the study. …”
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An Epidemiological Review of the Impact of COVID-19 on Achilles Tendon Rupture Injuries, Experience from a Large London District General Hospital by Lena Al-Hilfi, Irrum Afzal, Sarkhell Radha, Mohamed Abdalla, Mohammed Al-Maiyah

“…As lockdown measures began to ease, hospitals experienced a high admission rate of patients presenting with Achilles Tendon Rupture [ATR]. …”
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Performance Prediction of the Gearbox Elastic Support Structure Based on Multi-Task Learning by Chengshun Zhu, Zhizhou Lu, Jie Qi, Meng Xiang, Shilong Yuan, Hui Zhang

“…The adaptive gating mechanism, hierarchical nonlinear transformation, and effective capture of temporal dynamics in the LSTM significantly enhance the model’s ability to model complex nonlinear patterns. …”
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Anthropogenic Activities Dominate Vegetation Improvement in Arid Areas of China by Yu Guo, Xinwei Wang, Hongying Cao, Qin Peng, Yunshe Dong, Yunchun Qi, Jian Liu, Ning Lv, Feihu Yin, Xiujin Yuan, Mei Zeng

“…The results indicated that (1) overall vegetation cover was low (averaged peak FVC = 0.191), showing a spatial pattern of higher values in the northwest and lower values in the southeast; high FVC values were primarily observed in mountainous areas and river corridors; (2) the annual peak FVC increased significantly at a rate of 0.0508 yr⁻¹, with 33.72% of the region showing significant improvements and 5.49% degradation; (3) the spatial pattern of FVC was shaped by the distribution of land use types (59.46%), while the temporal dynamics of FVC were driven by land use changes (16.37%) and the land use intensity (37.56%); (4) both the spatial pattern and the temporal dynamics were limited by the environmental conditions. …”
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Analysis of single-cell and spatial transcriptomics in TNBC cell-cell interactions by Yan Xin, Qiji Ma, Qiang Deng, Tielin Wang, Dongxu Wang, Gang Wang

“…Triple-negative breast cancer (TNBC) is a highly malignant tumor in women, characterized by high morbidity, mortality, and recurrence rates. Although surgical treatment, radiotherapy, and chemotherapy are the mainstays of current treatment methods, the high heterogeneity of TNBC results in unsatisfactory outcomes with low 5-year survival rates. …”
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Censoring Sensitivity Analysis for Benchmarking Survival Machine Learning Methods by János Báskay, Tamás Mezei, Péter Banczerowski, Anna Horváth, Tamás Joó, Péter Pollner

“…The framework systematically reduced observation periods and increased censoring rates while measuring performance through multiple metrics following Bayesian hyperparameter optimization. (3) Results: Model performance showed greater sensitivity to increased censoring rates than to reduced observation periods. …”
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Socioeconomic and locational disparities in primary education completion in Burkina Faso by Lazarus Obed Livingstone Banda

“…Design/methodology/approach – Using a quantitative, non-experimental approach, the study analyzes nationally representative secondary data using hierarchical linear modeling, binary logistic regression and propensity score matching (PSM) to assess correlational patterns in completion rates. Findings – The results indicate significant regional and urban-rural disparities in completion rates, with urban students showing markedly higher odds of completing primary education than their rural peers. …”
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Patient Adherence for Oral Combination Therapies in Diabetes Management: A Scoping Review by Maryam Zarrinkamar, Mojgan Geran, Mohammad Geran

“…Dual therapy regimens demonstrated adherence rates ranging from 49% to 80.8%, while FDC therapies showed adherence rates ranging from 60.3% to 98.9%. …”
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The major risk factor of stroke across Indonesia; a nationwide geospatial analysis of universal health coverage program by Andi Alfian Zainuddin, Rais Reskiawan A. Kadir, Hedi Kuswanto, Jumraini Tammasse, Nurul Qalby, Andi Afdal Abdullah, Ari Andini Junaidi, Al Asyary

“…Methods The data were collected from the Social Health Insurance Administration Body, which manages Indonesia’s universal health coverage, between 2017 and 2022. Crude incidence rates for the diseases were calculated and spatial distribution patterns were analyzed using Global and local Moran analysis. …”
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Electrical Activity of the Gastrointestinal Tract in Critically Ill Patients by E. V. Alekseeva, T. S. Popova, P. S. Salnikov, G. A. Baranov, I. N. Pachechnik

“…With an increase in the total severity of the condition and in the magnitude of IF regardless of the disease profile, there were unilateral GIT EA changes, their moderate and rather high correlation with APACHE II, SAPS II, SOFA, LOD scores, IF stage — with 28-day survival rates. The use of glutamine provided an increase in 28-day survival rates in patients with an APACHE II score of > 15 scores and type 2 GIT EA. …”
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Clinical and survival differences between second primary and first primary nasopharyngeal carcinoma in a retrospective study by Xin Huang, Ying Kong, Tianyu Wu, Zhen Meng, Min Kang

“…Therapeutically, 2nd NPC patients showed significantly lower rates of curative-intent treatment (75.6% vs. 91.3%, p = 0.010), lower rates of good treatment tolerance (86.7% vs. 96.1%, p = 0.068), reduced chemotherapy utilization (73.3% vs. 89.3%, p = 0.014), and less frequent cisplatin use during concurrent chemotherapy (66.7% vs. 84.4%, p = 0.034). …”
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Evolution of the Diagnosis and Treatment of Acute Respiratory Distress Syndrome on the Basis of Up-to-Date Medical Technologies by Yu. V. Marchenkov, A. V. Vlasenko, V. V. Moroz, V. N. Yakovlev

“…The developed and clinically introduced new scientifically grounded methods for the prevention, diagnosis, and combination, differentiated treatment of ARDS could reduce the number of complications, the duration of mechanical ventilation, the length of stay in the intensive care unit, and mortality rates. Key words: acute respiratory distress syndrome, V. …”
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Diphtheria and its prevention by Ryabenko Yu.N., Ryabenko E.B.

“…The article analyzes statistical data on the incidence of diphtheria in the Russia at the end of the XX and the beginning of XXI century, provides absolute and relative intensive incidence rates in the country level, examines the patterns of the epidemic process, and defines the role of population antitoxic postvaccination immunity in the prevention of this infection. …”
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Pleural mesothelioma incidence and use of systemic treatment decreased during the COVID-19 pandemic in The Netherlands by Illaa Smesseim, Li-Anne H. Douma, Jacobus A. Burgers, Ronald A. M. Damhuis

“…Incidence, treatment patterns, and survival rates were analyzed using statistical methods, including Kruskal–Wallis and log-rank tests. …”
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Molecular epidemiology of <i>Pseudomonas aeruginosa</i> in intensive care units by Demet Timur, Mustafa Ömür Parkan, Esma Gündüz Kaya

“…Results: the resistance rates of the strains for amikacin, gentamicin, ciprofloxacin, levofloxacin, ceftazidime, cefepime, imipenem, meropenem, colistin were 2.7%,18.7%, 38.7%, 22.7%, 16%, 5.3%, 64%, 60%, and 2.7% respectively. …”
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Does rail transit access affect firm dynamics? Analysis of firm births and closures in Maryland, USA by Basheer Saeed, Hiroyuki Iseki

“…From 1991 to 2009, areas within close proximity to passenger rail stations in Maryland experienced a wide range of rates of growth in firm density, depending on the year of station opening. …”
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A dynamic early warning model based on LSTM-AM for property-based elderly care resource shortages in urban-rural integrated counties in China by Qingheng Sun

“…Results show that, taking Xuchang City, Henan Province as an example, by integrating multi-source time-series data such as county-level population aging rates, property-based elderly care service coverage rates, community facility maintenance data, and resident demand feedback, the model’s prediction error (MAE ≤ 0. 12, RMSE ≤ 0. 18) was reduced by 35% compared to traditional methods, and the warning accuracy (F1-score = 0. 89) was significantly superior to traditional models. …”
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The thermal stress response of Aedes aegypti and Aedes albopictus when exposed to rapid temperature changes by Hunter O. Covey, Randall Wilson, Yaizeth Gurrola-Mares, Joseph R. McMillan, Corey L. Brelsfoard

“…Respiration rates as a measure of thermal stress varied with rearing conditions and exposure temperatures, with notable declines observed as exposure temperatures increased. …”
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Global burden of breast cancer and application of patient-reported outcomes in clinical trials: a systematic analysis based on the global burden of disease study 2021 and WHO inter... by Jiaxin Hao, Jiaxin Hao, Yijia Gong, Yijia Gong, Xiaowen Zhang, Xiaowen Zhang, Xiaowen Zhang, Minghong Du, Minghong Du, Minghong Du, Huan Wang, Huan Wang, Huan Wang, Guolin Guo, Mengqing Zhou, Tian Tian, Hongguo Rong, Hongguo Rong, Hongguo Rong

“…This study analyzes geographic patterns, temporal trends and age patterns of female breast cancer disease burden globally and explored the association between age standardised rates for disability adjusted life years (ASDR) of female breast cancer and sociodemographic index (SDI). …”
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Adherence to Pharmacological Management Guidelines for Stable Chronic Obstructive Lung Disease by Sang Min Han, Hyo Seon Kim, Seung Yong Park, Heung Bum Lee, Young Bum Park, Chin Kook Rhee, Youlim Kim, Seoung Ju Park

“…When analyzing inhaler prescription patterns according to both subgroups and considering the Korean 2018, GOLD 2019, and GOLD 2023 guidelines concurrently, the adherence rates were as follows: (56.6%, 37.8%, 24.0%) and (57.7%, 14.0%, 38.6%). …”
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