Epigenetic dysregulation-induced metabolic reprogramming fuels tumor progression in bladder cancer by Jian Zhang, Xiaosong Fan, Xu Xu, Yichao Han, Weixing Yu, Bicheng Yang, Yanling Chen, Shaolin Zhang

“…BackgroundBladder cancer remains a significant global health challenge with a high mortality rate despite advancements in treatment modalities. …”
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Assessment of Water Resources Carrying Capacity and Analysis of Its Coupling Coordination in the Yangtze River Economic Belt by XIONG Ying, JIANG Yi-xin, CHEN Si-xuan

“…Analysis of influencing factors identified the proportion of tertiary industry, urbanization rate, and per capita daily domestic water consumption as the three factors most strongly correlated with water resources carrying capacity. …”
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Assessment of heavy metal pollution sources and environmental capacity of typical farmland soils in northwestern Zhejiang based on the geological background of black rock series by Mei-hua Wang

“…Principal component analysis extracted four principal components with a cumulative contribution rate of 78.92%, and the spatial distribution differences were obvious. …”
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Eco-friendly QbD-optimized chromatographic method for simultaneous analysis of metronidazole and nicotinamide with applications in permeation, stability, and sustainability evaluat... by Kanaka Parvathi Kannaiah, Mohamed A. M. Ali, Hemanth Kumar Chanduluru, Anis Ahmad Chaudhary, Mahmoud El-Maghrabey, Reem H. Obaydo, Galal Magdy, Mohamed A. El Hamd

“…Chromatographic separations were conducted with an RP-HPLC-photodiode array (PDA) system equipped with an ODS column using gradient elution of ethanol and phosphate buffer (10 mM, pH 3.5) at a flow rate of 1.0 mL/min. pre-optimized conditions were determined using a two-level full factorial design (23 FFD). …”
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Longitudinal evaluation of common and unique brain-networks in variants of primary progressive aphasia by Rajan Kashyap, Rose Dawn Bharath, Changsong Zhou, Kyrana Tsapkini, John E. Desmond, SH Annabel Chen, Kaviraja Udupa, PT Sivakumar, Sagarika Bhattacharjee

“…To validate the rsfMRI networks and the longitudinal changes, we evaluated the grey matter (GM) volume, GM atrophy and the rate-of-atrophy of the brain areas. To corroborate the findings, we applied persistent homology on the structural networks derived from diffusion tensor images. …”
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A novel twin time series network for building energy consumption predicting. by Zhixin Sun, Han Cui, Xiangxiang Mei, Hailei Yuan

“…To overcome these issues, the study proposes Twin Time-Series Networks (T2SNET), which incorporates a time-embedding layer and a Temporal Convolutional Network (TCN) to extract patterns from Complete Ensemble Empirical Mode Decomposition with Adaptive Noise (CEEMDAN), along with an adaptive fusion gate to combine energy consumption and meteorological data. …”
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Collective and individual adaptation of rice farmers to climatic variability in the Vietnamese Mekong Delta by Hieu Hong Hua, Minh Anh Nguyen, Thuy Thanh Thi Ngo

“…It systematically explores the patterns of climate variability and their profound impacts on rice production across diverse areas within the delta. …”
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Inflammatory Bowel Disease in Australasian Children and Adolescents by A. S. Day, D. A. Lemberg, R. B. Gearry

“…Many reports indicate increasing rates of inflammatory bowel disease, with data also showing changing patterns of this chronic disease in children and adolescents. …”
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The optimal strategy for seasonal influenza vaccination to prevent high-intensity level of influenza epidemics in Zhejiang, China: an integrated transmission-dynamic and health-eco... by Mengsha Chen, Mengya Yang, Rui Yan, Zhengwei Liu, Can Chen, Rongrong Qu, Wenkai Zhou, Jiaxing Qi, Kexin Cao, Jiani Miao, Xiaoyue Wu, Jiaxin Chen, Qianqian Feng, HuiHui Zhang, Anqi Dai, Yi Yang, Jingtong Zhou, Qin Chen, Jimin Sun, Shigui Yang

“…High-intensity outbreaks were defined as weekly incidence rates above 72.2 per 100,000. Methods This study estimated the incidence of influenza from 2018 to 2023 in Zhejiang Province, China, using influenza weekly surveillance data. …”
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Nitrogen reduction with supplemental irrigation enhances yield by delaying leaf senescence and optimizing grain-filling process for ridge-furrow film mulching winter wheat by Xiaobo Gu, Yang Xu, Tongtong Zhao, Yadan Du, Yuanling Zhang, Yuyu Tian, Zhikai Cheng, Huanjie Cai, Zhandong Liu

“…However, the optimal supplemental irrigation rate to further increase the yield of winter wheat under RFM remains unclear. …”
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Early-stage endometrioid carcinoma with MSH6 protein deficiency: pitfalls in the diagnostic interpretation of microsatellite instability by Cheng Wang, Cheng Wang, Dongni Liang, Dongni Liang, Wei Wang, Wei Wang, Wei Kuang, Wei Kuang, Juan Zou, Juan Zou, Jing Zeng, Jing Zeng, Min Feng, Min Feng

“…This atypical MSI pattern is often overlooked, potentially increasing the risk of underdiagnosis of LS.…”
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Revealing the effect of layer-varying deposition strategy on laser-directed energy deposition bionic gradient NiTi alloy by Zhongxiong Kang, Chaorui Jiang, Mengqi Liu, Zhihui Zhang, Jie Zhao

“…The strategy includes different process parameters (the laser power and scanning speed), the scanning paths (alternative optimised spiral pattern, x-axis rotation pattern, and arc alternative pattern) and interlayer interval time. …”
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Design of a Low Threshold Single-Mode In-P Laser Using Regrowth-Free Fabrication by A. Sharma, P. Landais, M. Srivastava, M. Wallace, F. Smyth, A. Kaszubowska-Anandarajah, P. Anandarajah

“…Subsequently, the extracted parameters are used in a rate equation model to predict the performance of the laser in terms of its L <inline-formula><tex-math notation="LaTeX">$ - $</tex-math></inline-formula> I characteristics and the sidemode suppression ratio (SMSR). …”
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A spatiotemporal model for urban taxi Origin–Destination prediction based on Multi-hop GCN and Hierarchical LSTM by Jiang Rong, Wangtu Xu, Yanjie Wen

“…HLSTM unit incorporates a standard LSTM gate to manage cell state updates, enabling selective access to the internal memory. …”
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Optimization of ivacaftor-loaded solid lipid nanoparticles for solubility enhancement by Akshay Parihar, Akshay Parihar, Bhupendra G. Prajapati, Bhupendra G. Prajapati, Bhupendra G. Prajapati, Himanshu Paliwal

“…The in vitro dissolution study showed improved release pattern from the optimized formulation and release profile followed first-order model indicating a sustained release pattern from lipid matrix.ConclusionThis delivery system presented development of stable nanoparticle formulation exhibiting sustained release pattern, which may contribute to therapeutic outcomes in comparison with drug alone. …”
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Evaluation of planting arrangment and methods on quantitative and qualitative characteristics of tomato (Lycopersicon esculentum) seeds by H. Khazaei

“…The highest and lowest fruit and seed yield were obtained in Rokh (two row per ridge and 120×30 cm planting pattern) and Toroq (one row per ridge and 140×50 cm planting pattern) regions, respectively with 2.7 and 3.1 times difference. …”
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Evaluating anti-MRSA antibiotic stewardship with a focus on trends in consumption and resistance in a tertiary hospital in Alexandria, Egypt from 2019 to 2023 by Ehab Elmongui, Adel Zaki, Amel Elsheredy, Asmaa Abd Elhameed

“…The study compared these consumption patterns with resistance rates in Staphylococcus spp., including MRSS, from January 2020 to December 2023. …”
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Heating Experiments on Benthic Foraminifera Ammonia sp. to Assess the Suitability of Amino Acid-Based Dating by Rahmadi Hidayat, Didit Hadi Barianto, Sugeng Sapto Surjono, Che Aziz Ali

“…The racemization rate differs from four selected amino acids reported in this study, where aspartic acid is the fastest, followed by glutamic acid, valine and isoleucine epimerization. …”
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Assessment of the experimental infection by Echinostoma paraensei (Lie & Basch, 1967) (Trematoda: Echinostomatidae) in two Biomphalaria tenagophila (D’Orbigny, 1835) (Gastropoda: P... by Michele Maria Santos, Juberlan Silva Garcia, Raquel de Oliveira Simões, Samaly dos Santos Souza, Paulo Marcos Zech Coelho, Zilton de Araújo Andrade, Arnaldo Maldonado Júnior

“…A correlation between the number of miracidia and the infectivity rate of B. tenagophila (TAIM) was observed. There was no correlation between the number of miracidia used and the number of cercariae released for both B. tenagophila isolates. …”
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Análisis técnico-económico para selección de aspersores Technical and economical analysis for sprinkler selection by Eduardo A. Holzapfel, Ximena M. Pardo, Vital P. da S. Paz, Antonieta Rodrigues, Ximena C. Orrego, Marco A. Lopez

“…To accomplish this an analysis was performed of different factors such as rate of water application, available time for irrigation, wind velocity, distribution pattern and pressure. …”
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