Epstein Barr virus antibody and cancer risk in two prospective cohorts in Southern China by Ming-Fang Ji, Yong-Qiao He, Min-Zhong Tang, Wen-Qiong Xue, Xia Yu, Hua Diao, Da-Wei Yang, Zhi-Ming Mai, Io Hong Cheong, Zhi-Yang Zhao, Biao-Hua Wu, Fu-Gui Li, Ji-Yun Zhan, Chang-Ling Huang, Hao-Lin Ma, Jun Li, Yan-Cheng Li, Tong-Min Wang, Ying Liao, Xue-Yin Chen, Zhi-Heng Liang, Shi-Feng Lian, Yun Du, Xue-Jun Liang, Zisis Kozlakidis, Jun Ma, Wei-Hua Jia

“…The associations showed an increased dose-response pattern, and keep persistent even up to ten years prior to diagnosis. …”
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Multiple sclerosis mortality trends in Spain from 1981 to 2020 by L. Cayuela, A. de Albóniga-Chindurza, S. Gómez Enjuto, J. Lapeña-Motilva, S. Sainz de la Maza, A. González García, A. Cayuela

“…Age-standardised mortality rates (ASMR) and trend analysis were performed using joinpoint regression software. …”
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Pronounced effects of the sepsis–obesity paradox in elderly and male individuals without septic shock and the role of immune–inflammatory status: an analysis of MIMIC-IV data by Zhe Xu, Zhuojie Li, Ruguo Zhang, Guoxuan Peng, Jingzhong Ge, Shanpeng Luo, Chen Liu, Ling Zeng, Jin Deng

“…Body mass index (BMI) was divided into quartiles, and mortality rates were assessed for each interval. Logistic trend tests and subgroup and restricted cubic spline (RCS) analyses were performed. …”
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Inwardly rectifying potassium channels: Critical insights for insect species and Apis mellifera by Fabien Sourisseau, Craig A. Doupnik, Pierre Charnet, Mohamed Chahine

“…This review provides a comprehensive overview of current knowledge about Kir channel structures, activities, and gating as well as of their roles in insects, including evolutionary genomic aspects, molecular biology, physiological roles, and pharmacological targeting.…”
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SERPINA3 predicts long-term neurological outcomes and mortality in patients with intracerebral hemorrhage by Pei Zheng, Zhihui Qi, Bin Gao, Yang Yao, Jingshan Chen, Hengri Cong, Yue Huang, Fu-Dong Shi

“…Abstract Intracerebral hemorrhage (ICH) is a severe stroke subtype with high mortality and disability rates, and long-term outcomes among survivors remain unpredictable due to the lack of reliable biomarkers. …”
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Review of Epidemiological Situation on Rickettsioses in the Russian Federation in 2022 as Compared with 2013–2021, Forecast for 2023 by N. A. Pen’evskaya, N. V. Rudakov, S. N. Shpynov, A. I. Blokh, D. V. Trankvilevsky, D. A. Savel’ev, S. V. Shtrek, A. V. Sannikov

“…The aim of the review was to characterize the epidemiological situation on tick-borne rickettsioses (TR) in the Russian Federation in 2022 in comparison with the pandemic years of 2020–2021 and the pre-pandemic period of 2013–2019, to give the forecast for 2023. During 2013–2022, a pattern was observed in the incidence of rickettsiosis of the tick-borne spotted fever group (with the exception of Astrakhan spotted fever – ASF), that is also characteristic of most other natural focal infections (NFIs): a sharp decrease in registered incidence rates in 2020–2021 with the subsequent increase in 2022 almost up to pre-pandemic levels or even exceedance in some regions. …”
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Psychiatric comorbidities and smoking behavior in chronic obstructive pulmonary disease: A case–control study from a north Indian tertiary Center by Rohit Pathak, Abhishek Pathak, Manish Singh

“…Results: Cases exhibited significantly higher rates of smoking, with regular smokers constituting 51.1% compared to 14.0% of controls (P=0.0001). …”
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Content-Based Brain Magnetic Resonance Image Retrieval and Classification With the Proposed Deep Learning and Tissue-Based System by Bedriye Dogan, Hursit Burak Mutlu, Muhammed Yildirim, Sercan Yalcin, Serpil Aslan, Niranjana Sampathila, Ozal Yildirim, Edward J. Ciaccio, Ru-San Tan, U. Rajendra Acharya

“…Notably, existing machine architectures already published in the literature have struggled to achieve comparable success rates in discerning such closely related yet distinct disease groups. …”
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Clinical features of patients with dysthymia in a large cohort of Han Chinese women with recurrent major depression. by Wenqing Wu, Zhoubing Wang, Yan Wei, Guanghua Zhang, Shenxun Shi, Jingfang Gao, Youhui Li, Ming Tao, Kerang Zhang, Xumei Wang, Chengge Gao, Lijun Yang, Kan Li, Jianguo Shi, Gang Wang, Lanfen Liu, Jinbei Zhang, Bo Du, Guoqing Jiang, Jianhua Shen, Ying Liu, Wei Liang, Jing Sun, Jian Hu, Tiebang Liu, Xueyi Wang, Guodong Miao, Huaqing Meng, Yi Li, Chunmei Hu, Yi Li, Guoping Huang, Gongying Li, Baowei Ha, Hong Deng, Qiyi Mei, Hui Zhong, Shugui Gao, Hong Sang, Yutang Zhang, Xiang Fang, Fengyu Yu, Donglin Yang, Tieqiao Liu, Yunchun Chen, Xiaohong Hong, Wenyuan Wu, Guibing Chen, Min Cai, Yan Song, Jiyang Pan, Jicheng Dong, Runde Pan, Wei Zhang, Zhenming Shen, Zhengrong Liu, Danhua Gu, Xiaoping Wang, Xiaojuan Liu, Qiwen Zhang, Yihan Li, Yiping Chen, Kenneth S Kendler, Jonathan Flint, Zhen Zhang

“…<h4>Conclusions</h4>There are increased rates of stressful life events in MDD with dysthymia, but the impact of life events on susceptibility to dysthymia with MDD differs from that seen for MDD alone. …”
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A Long-Term Overview of Elasmobranch Fisheries in an Oceanic Archipelago: A Case Study of the Madeira Archipelago by Mafalda Freitas, Filipa Pinho-Duarte, Madalena Gaspar, Pedro Ideia, João Delgado, Sara C. Cerqueira, Ricardo Sousa

“…The most representative period occurred from 2003 to 2013, corresponding to 75.21% of the total elasmobranch landings. A general pattern of supply and demand was evident, with mean price values typically showing an inverse trend to landed tonnage. …”
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Toxicokinetics, tissue distribution, and toxic potency of PFOS alternative OBS in adult zebrafish (Danio rerio) based on flow-through exposure system by Yilong Zou, Yu Zhou, Xianglian Wang, Guiqing Gao, Gang Chen, Zhanmeng Liu, Mi Deng, Xueping Huang, Yongming Wu

“…Our findings indicate that OBS accumulated rapidly in zebrafish, with log kinetic bioconcentration factor (logBCFk) values ranging from 2.48 to 2.70 and slow elimination rates (ke = 0.0490–0.0643 d−1). The blood, liver, and muscle were responsible for over 50 % of the total body burden of OBS, with tissue concentrations decreasing in the following order: blood > liver > intestine > gills > gonad > brain > muscle, suggesting a tissue-specific accumulation pattern. …”
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Causes of maternal deaths in Sierra Leone from 2016 to 2019: analysis of districts’ maternal death surveillance and response data by Francesco Barone-Adesi, Francesca Tognon, Fabio Manenti, Marta Caviglia, Yasir Shafiq, Zainab Juheh Bah, Michele Orsi, Abibatu K. Kamara, Caracciolo Claudia, Francis Moses, Tom Sessay

“…Introduction Sierra Leone is among the top countries with the highest maternal mortality rates. Although progress has been made in reducing maternal mortality, challenges remain, including limited access to skilled care and regional disparities in accessing quality care. …”
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The large and central Caligo martia eyespot may reduce fatal attacks by birds: a case study supports the deflection hypothesis in nature by Iserhard, Cristiano Agra, Malta, Shimene, Penz, Carla, Fraga, Brenda Barbon, Costa, Camila Abel, Schwantz, Taiane, Bordin, Kauane Maiara

“…Eyespots did not appear to reduce attack rates, suggesting that local bird species were not intimidated. …”
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Efficacy and safety of herbal medicine (Dangguijagyag-san) for primary dysmenorrhea: study protocol for a randomized, double-blind, placebo-controlled, parallel-group, multi-center... by Hye Lin Woo, Hae Ri Ji, Siin Kim, Hae Sun Suh, Kwan-Il Kim, Jin Moo Lee, Kyoung Sun Park

“…The primary outcomes are difference in response rates between the EG and the ACG (non-inferiority comparison) and difference in changes from baseline in average pain intensity measured by the visual analogue scale between the EG and PCG (superiority comparison). …”
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Dysregulated neural coding in the vagus nerve during long sepsis by Joshua J. Strohl, Tomás S. Huerta, Sergio Robbiati, Patricio T. Huerta

“…We found that LS mice exhibited significantly higher baseline vagal activity compared to controls, with elevated firing rates during both respiratory bursts and inter-burst intervals. …”
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Reward-related neural activation during social media exposure in young women with non-suicidal self-injury: evidence for a continuum of severity in the reward network by Stella Nicolaou, Anna Julià, Daniela Otero, Carlos Schmidt, Juan Carlos Pascual, Joaquim Soler, Josep Marco-Pallarés, Daniel Vega

“…Clinical participants rated positive comments as less pleasant and negative comments as more unpleasant than controls. …”
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IRF-3, IRF-5, and IRF-7 coordinately regulate the type I IFN response in myeloid dendritic cells downstream of MAVS signaling. by Helen M Lazear, Alissa Lancaster, Courtney Wilkins, Mehul S Suthar, Albert Huang, Sarah C Vick, Lisa Clepper, Larissa Thackray, Margaret M Brassil, Herbert W Virgin, Janko Nikolich-Zugich, Ashlee V Moses, Michael Gale, Klaus Früh, Michael S Diamond

“…Whereas the gene induction pattern in DKO mDC was similar to WT cells, remarkably, almost no ISG induction was detected in TKO or Mavs(-/-) mDC. …”
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Dual orexin receptor antagonists for the treatment of insomnia: systematic review and network meta-analysis by Rebeka Bustamante Rocha, Fernanda Ferreira Bomtempo, Gabriela Borges Nager, Giulia Isadora Cenci, João Paulo Mota Telles

“…Concerning TST, an apparent dose-dependent pattern was noticed, with higher doses relating to a longer TST. …”
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In Silico Designed Multi-Epitope Vaccine Based on the Conserved Fragments in Viral Proteins for Broad-Spectrum Protection Against Porcine Reproductive and Respiratory Syndrome Viru... by Shaukat Ullah, Hikmat Ullah, Kainat Fatima, Tan Lei

“…This virus includes two major genotypes, PRRSV1 and PRRSV2, both characterized by high mutation rates and genetic variability, complicating the development of a universally effective vaccine and disease control. …”
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Cumulative risk of revision after primary total hip arthroplasty in registries internationally: systematic review and meta-analysis of selected hip stems and cups by Christophe Combescure, James A Smith, Christophe Barea, Lotje A Hoogervorst, Rob Nelissen, Perla J Marang-van de Mheen, Anne Lübbeke, the Arthroplasty registry group

“…Purpose: The objective was to investigate the consistency in cumulative revision rates (CRRs) for a selection of total hip arthroplasty cups and stems across national/regional hip arthroplasty registries worldwide. …”
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