Triatoma dimidiata, domestic animals and acute Chagas disease: a 10-year follow-up after an eco-bio-social intervention by Jose G. Juarez, Andrea M. Moller-Vasquez, María Granados-Presa, Pamela Pennington, Norma Padilla, Sujata Balasubramanian, Lisa D. Auckland, Elsa Berganza, Estuardo Alvarado Liberato, Henry Esquivel, Ranferi Trampe, Louisa A. Messenger, Celia Cordón-Rosales, Gabriel L. Hamer, Sarah A. Hamer

“…Results Persistent household infestation by T. dimidiata was observed across all four communities, with infestation rates ranging from 17% to 38% and colonization levels ranging from 9% to 29%. …”
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Ten-year trends in opioid prescribing and vaso-occlusive crises in sickle cell disease: a population-based national cohort study (2011–2022)Research in context by Kevin Y. Xu, Terri V. Newman, Lakeya S. McGill, Enrico M. Novelli, Cheryl A. Hillery, Joanna L. Buss, Lisa Gong, Ruizhi Huang, Fanghong Dong, Dustin Stwalley, Joanne Salas, Shiyuan A. Liu, Jeffrey F. Scherrer, Tashalee R. Brown, Tae Woo Park, Marc R. LaRochelle, Richard A. Grucza, Charles R. Jonassaint

“…Primary outcomes were monthly rates of outpatient opioid prescriptions and VOC-related acute care encounters. …”
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Antidepressant Switching as a Proxy Phenotype for Drug Nonresponse: Investigating Clinical, Demographic, and Genetic Characteristics by Chris Wai Hang Lo, Alexandra C. Gillett, Matthew H. Iveson, Michelle Kamp, Chiara Fabbri, Win Lee Edwin Wong, Dale Handley, Oliver Pain, Evangelos Vassos, Naomi R. Wray, Heather C. Whalley, Danyang Li, Allan H. Young, Andrew M. McIntosh, Cathryn M. Lewis

“…Background: Selective serotonin reuptake inhibitors (SSRIs) are a first-line pharmacological therapy in major depressive disorder (MDD), but treatment response rates are low. Clinical trials lack the power to study the genetic contribution to SSRI response. …”
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Long-term outcomes of dupilumab therapy in severe asthma: A retrospective, multicenter, real-world study by Carlo Mümmler, MD, Alexandra Lenoir, MD, Jeremias Götschke, MD, Michael Gerckens, MD, Merle Kaiser, MD, Moritz Kayser, MD, Nora Drick, MD, Hendrik Suhling, MD, Leonie Biener, MD, Carmen Pizarro, MD, Dirk Skowasch, MD, Nikolaus Kneidinger, MD, PhD, Jürgen Behr, MD, Katrin Milger, MD

“…Real-world data on the continuation and cessation patterns of dupilumab and long-term treatment efficacy are scarce. …”
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Oncolytic Vaccinia Virus Armed with GM-CSF and IL-7 Enhances Antitumor Immunity in Pancreatic Cancer by Wenyi Yan, Yujing Xuan, Ruimin Wang, Ziyan Huan, Yu Guo, Huilin Dun, Lihua Xu, Ruxia Han, Xianlei Sun, Lingling Si, Nicholas Robert Lemoine, Yaohe Wang, Pengju Wang

“…The synergistic effects of VVL-GL7 and the PD-1 blockade further improved therapeutic outcomes, resulting in significantly higher tumor remission rates compared to monotherapy and achieving complete tumor regression in pancreatic cancer models. …”
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Spatio-Temporal Characteristics and Driving Forces of Landscape Ecological Risks in Highly Urbanized Areas: A Case Study of Suzhou City by Lingyue LU, Dawei SHAO, Dianming WU

“…However, relatively little attention has been given to urbanized areas characterized by high rates of population growth and land development. …”
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A longitudinal qualitative study of clinical nurses caring for hospitalized adults during the first fifteen months of COVID-19: lessons in professional survival and leadership by Elizabeth M. Norman, Mildred Ortu Kowalski, Roxanne Sabatini, Carol S. Jones, Wendy Silverstein

“…At the time of this April surge, nurses were exposed to a virus with no standard treatments and high mortality rates. Using a longitudinal qualitative design, the team hoped to answer questions about what compelled these nurses to continue to come to work? …”
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Toward improving retention in HIV care after pregnancy: lessons from a post-pandemic cohort in the United States by Alexandra H. Latham, Alexandra H. Latham, Alexandra H. Latham, Andrea Lugo Morales, Andrea Lugo Morales, Andrea Lugo Morales, Elizabeth Barba Gutierrez, Elizabeth Barba Gutierrez, Elizabeth Barba Gutierrez, Michael Jochum, Michael Jochum, Sarah Conrad, Sarah Conrad, Eva H. Clark, Kassandra Goytia, Megan Alam, Jessica Gerard, Jessica Gerard, Jennifer McKinney, Jennifer McKinney, Jennifer McKinney

“…IntroductionPeople living with HIV (PLWH) often experience low rates of retention in HIV care (RIC) and suboptimal viral suppression postpartum. …”
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Seasonal population dynamics and dietary switching of Vulpes spp. amplify Echinococcus spp. transmission in the Eastern Tibetan plateau: implications for wildlife-mediated zoonotic... by Xu Wang, Chuizhao Xue, Xueying Deng, Qilu Chen, Chunyang Li, Baixue Liu, Ying Wang, Yan Kui, Qingqiu Zuo, Jianhai Yin, Shuai Han, Yujuan Shen, Jianping Cao

“…This dietary diversification correlated with seasonal resource scarcity, driving foxes to exploit alternative prey. The infection rates of Echinococcus in V. ferrilata displayed the U-shaped seasonal patterns. …”
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Preparation of land subsidence susceptibility map using machine learning methods based on decision tree (case study: Isfahan–Borkhar) by Negar Ghasemi, Iman Khosravi, Ali Bahrami

“…Studies estimate that approximately 3.5% of Iran's land area has been affected by subsidence, with some regions showing annual sinking rates of over 10 centimeters. Such rates are alarmingly high and have direct implications for urban development, agriculture, and even national heritage conservation. …”
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Decentralized Immunization Monitoring: Lessons Learnt from a Pilot Implementation in Kumbotso LGA, Kano State, Nigeria by Adam Attahiru, Yahaya Mohammed, Fiyidi Mikailu, Hyelshilni Waziri, Ndadilnasiya Endie Waziri, Mustapha Tukur, Bashir Sunusi, Mohammed Nasir Mahmoud, Nancy Vollmer, William Vargas, Yusuf Yusufari, Gustavo Corrêa, Heidi W. Reynolds, Teemar Fisseha, Talatu Buba Bello, Moreen Kamateeka, Adefisoye Oluwaseun Adewole, Musa Bello, Imam Wada Bello, Sulaiman Etamesor, Joseph J. Valadez, Patrick Nguku

“…Univariate and bivariate analyses were performed to show patterns and relations across variables. Results: Out of 418 caregivers surveyed, 98.1% were female. …”
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Geographical variation of overweight, obesity and related risk factors: Findings from the European Health Examination Survey in Luxembourg, 2013-2015. by Hanen Samouda, Maria Ruiz-Castell, Valery Bocquet, Andrea Kuemmerle, Anna Chioti, Frédéric Dadoun, Ngianga-Bakwin Kandala, Saverio Stranges

“…Large disparities in the prevalence of overweight and obesity were found between municipalities, with the highest rates of obesity found in 3 municipalities located in the South-West of the country. …”
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Fertility intentions among Chinese adults: a cross-sectional study using a national survey by Mingyan Hao, Chenxiao Zhang, Haofeng Fu, Jingting Zhang, Ziyi Zhang, Baotong Ma, Ruitong Xia, Yuanwei Lu, Jingwen Liu, Hanjia Xin, Yumeng Cao, Saier Yang, Runqing Li, Ji Zhao, Jin Zhang, Zheng Gao, Yaxin Zeng, Yixiao Ding, Zhuolun Ren, Yan Guan, Na Zhang, Jia Li, Yan Ma, Pei Wei, Jingjing Dong, Chen Chen, Yajing Zhou, Jianzhong Zheng, Wei Liu, Lizheng Wang

“…To tackle the challenge of decreasing fertility rates effectively, it is essential that interventions focus on younger women and highlight the advantages of living with multiple generations. …”
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Levels and types of physical activity in Russia according to the ESSE-RF study: is there a trace of the COVID-19 pandemic? by M. B. Kotova, S. A. Maksimov, S. A. Shalnova, A. V. Kontsevaya, Yu. A. Balanova, A. E. Imaeva, V. A. Kutsenko, G. A. Muromtseva, N. S. Karamnova, S. E. Evstifeeva, A. V. Kapustina, O. A. Litinskaya, M. S. Pokrovskaya, E. B. Yarovaya, T. V. Repkina, T. O. Gonoshilova, A. V. Kudryavtsev, N. I. Belova, L. L. Shagrov, M. A. Samotrueva, A. L. Yasenyavskaya, E. N. Chernysheva, S. V. Glukhovskaya, I. A. Levina, E. A. Shirshova, E. B. Dorzhieva, E. Z. Urbanova, N. Yu. Borovkova, V. K. Kurashin, A. D. Tokareva, Yu. I. Ragino, G. I. Simonova, A. D. Khudyakova, V. N. Nikulin, O. R. Aslyamov, G. V. Khokhlova, A. V. Solovyova, A. A. Rodionov, O. V. Kryachkova, Yu. Yu. Shamurova, I. V. Tantsyreva, I. N. Baryshnikova, M. G. Ataev, M. O. Radjabov, M. M. Isakhanova, M. A. Umetov, L. V. Elgarova, I. A. Khakuasheva, E. I. Yamashkina, M. V. Esina, T. A. Kunyaeva, A. M. Nikitina, N. V. Savvina, Yu. E. Spiridonova, E. A. Naumova, A. A. Keskinov, V. S. Yudin, S. M. Yudin, O. M. Drapkina

“…Compared to the urban population, rural residents have higher physical activity rates (23,9 vs 20,3%, p<0,001). The proportion of people with high physical activity is also higher among people with higher income levels (p<0,001). …”
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Dependence of Indicators of Daily Blood Pressure Monitoring on Activity of Pathological Process in Patients with Systemic Lupus Erythematosus by Abrahamovych O., Abrahamovych U., Kushyna A., Guta S., Synenkyi O.

“…According to the first goal was rated the BP in the SLE patients during the period of 24 hours, for which: a) were examined the average daily, maximum and minimum levels of systolic blood pressure (SBP), diastolic blood pressure (DBP), the average blood pressure; b) was analysed the daily index (DI) of SBP, DBP and the average blood pressure; c) was examined the time index (TI) of SBP, DBP and the average blood pressure. …”
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Risk of developing drug abuse in administration of a new hexaazaisowurtzitane derivative-based analgesic (experimental study) by S. G. Krylova, T. N. Pove’teva, K. A. Lopatina, Yu. V. Nesterova, E. P. Zueva, O. G. Afanas’eva, P. V. Kulpin, E. A. Kiseleva, N. I. Suslov, D. A. Kulagina, S. V. Sysolyatin, V. V. Zhdanov

“…Previous in vivo and in silico studies (docking, molecular modeling, molecular dynamics simulation) on the multi-target mechanism of thiowurtzine explain the absence of its morphine-like effect by the fact that the major targets of the analgesic are TRPA1 receptors and voltage-gated Ca 2+ channels. With a high degree of probability, the conclusions made herein predict no drug abuse development when thiowurtzine is used in the clinical setting. …”
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Numerical Simulation Study on the Dynamic Processes and Evolution Laws of Multiple Granular Flows in a Gully by LEI Ming, ZHANG Liang, YE Chen, WANG Xiekang

“…Compared with the first granular flow, subsequent ones feature shorter durations and higher energy dissipation rates. The velocity and displacement of base granules increase significantly as the friction coefficient decreases and the secondary slope increases. …”
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Investigation of methicillin, beta lactam, carbapenem, and multidrug resistant bacteria from blood cultures of septicemia suspected patients in Northwest Ethiopia by Abebe Birhanu, Getachew Gebre, Eden Getaneh, Hana Yohannes, Netsanet Baye, Gizeaddis Belay Mersha, Mitkie Tigabie, Mulat Dagnew, Getachew Ferede, Teshiwal Deress, Wondwossen Abebe

“…Gram-positive bacteria, particularly S. aureus, and gram-negative bacteria like K. pneumoniae and E. coli were predominant. High rates of methicillin, beta-lactam, and carbapenem resistance were observed, emphasizing the magnitude of antimicrobial resistance. …”
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Forecast of myocardial infarction incidence, events and prevalence in England to 2035 using a microsimulation model with endogenous disease outcomes. by Peter Scarborough, Asha Kaur, Linda J Cobiac

“…Age-standardised event rates show a similar pattern, with a non-significant upturn by 2035, larger for men than women. …”
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The evolution of irreversible cell differentiation under cell death effect. by Yuanxiao Gao, Xueyan Zhao, Caixia Li

“…We show that irreversible differentiation is more likely to occur when cell death rates between cell types are linear. Meanwhile, differences in death rates between cell types affect the emergence conditions of irreversible differentiation, whereas no significant impacts on that from equal cell death rates. …”
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