Inflammatory markers mediate the association between alternative adiposity indices and mortality in patients with rheumatoid arthritis: data from NHANES 1999–2018 by Feng Luo, Jia-jie Guo, Xue-mei Yuan, Heng Zhou, Qiu-yi Wang, Chang-ming Chen, Xue-ming Yao, Wu-kai Ma

“…Conclusions This study revealed a potential clinical value of a new obesity index, specifically the ABSI, in predicting the survival rates among individuals with RA. Inflammatory markers appear to play a partial mediating role in this relationship. …”
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Spatial distribution and predictors of early childbearing among Ethiopian women: evidence from the 2016 Ethiopian Demographic and Health Survey by Amare Teshome Tefera, Fanuel Gashaw, Martha Solomon, Nebiyu Bekele, Shegaye Shumet, Tigist Mulugeta, Araya Mesfin Nigatu, Solomon Gedlu Nigatu

“…Abstract Background Age at first birth is a crucial factor in understanding fertility patterns within a population. Ethiopia reports high rates of maternal and child mortality alongside elevated fertility levels. …”
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Comparison of neoadjuvant chemoimmunotherapy with planned surgery and concurrent chemoradiation followed by immunotherapy for potentially resectable stage III non-small-cell lung c... by Yana Qi, Xiaoyang Zhai, Qinhao Xu, Yuqin Jin, Yingfan Guo, Miaoqing Zhao, Hui Zhu, Hongbo Guo

“…Median overall survival (OS) was NR in either group, with 3-year OS rates of 87.5% in the neoCT/IO group and 75.0% in the cCRT + IO group (p = 0.22). …”
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Epidemiological and clinical analysis, and outcomes of tuberculosis co-infection among people living with HIV in Türkiye (2014-2024) ClinSurv HIV cohort: A large case series. by Ali Mert, Okan Derin, Esra Zerdali, Abdurrahman Kaya, Özlem Gül, Deniz Borcak, Ahmet Furkan Kurt, Meliha Meriç Koç, Bircan Kayaaslan, Ayşe Batırel, Alper Gündüz, İnci Yılmaz Nakir, Gülşen Yörük, Dilek Yıldız Sevgi, Hayat Kumbasar Karaosmanoğlu, Bilgül Mete, Melike Nur Özçelik, Nagehan D Sarı, Yasemin Akkoyunlu, Fehmi Tabak

“…The positivity rates of Ehrlich-Ziehl-Neelsen staining (EZN), polymerase chain reaction (PCR), and TB cultures in clinical samples were found to be 47.5%, 72.5%, and 53%, respectively. …”
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Conversational AI agent for precision oncology: AI-HOPE-WNT integrates clinical and genomic data to investigate WNT pathway dysregulation in colorectal cancer by Ei-Wen Yang, Brigette Waldrup, Enrique Velazquez-Villarreal, Enrique Velazquez-Villarreal

“…Exploratory queries further assessed treatment response, co-mutation patterns, and population-specific trends.ResultsIn recapitulation analyses, AI-HOPE-WNT reproduced key trends from prior work, including improved survival in WNT-altered EOCRC and higher RNF43 mutation rates in Hispanic/Latino (H/L) populations compared to non-Hispanic White (NHW) people. …”
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Estimating the burden of disease attributable to non-assisted suicide in Switzerland from 2009 to 2021: a secondary data analysis by Annora Mack, Sarah Rajkumar, Jacob Kofler, Kaspar Wyss

“…The stark sex disparity in suicide rates further underscores the need for sex-sensitive approaches. …”
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Heterogeneity of Candida bloodstream isolates in an academic medical center and affiliated hospitals by Nancy E. Scott, Elizabeth Wash, Christopher Zajac, Serin E. Erayil, Susan E. Kline, Anna Selmecki

“…Phenotypic data, including patterns of antifungal drug resistance, are limited. …”
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Factors affecting detection probability: Insights from banding data in a long-term continent-wide monitoring program by Morgane Gicquel, Juan C. Alonso, Lovisa Nilsson, Matthew Low, Javier A. Alonso, Dmitrijs Boiko, Damon Bridge, Patrick Dulau, Thomas Heinicke, Anne Kettner, Yosef Kiat, Petras Kurlavičius, Sigvard Lundgren, Michael Modrow, Günter Nowald, Ivar Ojaste, Alain Salvi, Jostein Sandvik, Markéta Ticháčková, Antonio Torrijo, Jari Valkama, Zsolt Végvári, Johan Månsson

“…In this study we investigate factors influencing detection rates of colour-banded Eurasian cranes (Grus grus), from a monitoring program spanning 35 years, involving 5049 marked individuals using four different types of bands (ELSA, ‘Finnish’, ‘Spanish’ and alphanumeric) with 172,725 resightings along migratory flyways. …”
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Epigenetic Alterations in Ovarian Function and Their Impact on Assisted Reproductive Technologies: A Systematic Review by Charalampos Voros, Antonia Varthaliti, Despoina Mavrogianni, Diamantis Athanasiou, Antonia Athanasiou, Aikaterini Athanasiou, Anthi-Maria Papahliou, Constantinos G. Zografos, Vasileios Topalis, Panagiota Kondili, Menelaos Darlas, Sophia Sina, Maria Anastasia Daskalaki, Marianna Theodora, Panos Antsaklis, Georgios Daskalakis

“…This systematic review investigates the significance of epigenetic pathways in ovarian function, with an emphasis on their effect on ART success rates. <b>Methods</b>: A thorough search of the PubMed, Scopus, and EMBASE databases was performed to find articles published between 2015 and 2024 that investigated the connection between epigenetic changes and ovarian function in ART patients. …”
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Symptom Trajectories and Clinical Subtypes in Post–COVID-19 Condition: Systematic Review and Clustering Analysis by Mingzhi Hu, Tian Song, Zhaoyuan Gong, Qianzi Che, Jing Guo, Lin Chen, Haili Zhang, Huizhen Li, Ning Liang, Guozhen Zhao, Yanping Wang, Nannan Shi, Bin Liu

“…Asia and Europe documented the most comprehensive symptom profiles, with Asia reporting lower early dyspnea rates (29%, 95% CI 18%‐40%) and Europe exhibiting more complex multisystem involvement during long-term follow-up. …”
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Exploring the profile and risk factors associated with self-harm ideation and behaviors in adolescents with high psychoticism by Xiao-Ming Xu, Ru-Hong Jiang, Yu-Shuang Han, Wo Wang, Ming Ai, Jian-Mei Chen, Jun Cao, Xiao-Rong Chen, Zhen Lv, He-Yan Xu, Da-Qin Ding, Su Hong, Jing-Lan He, Qi Zhang, Lei Shi, Ning Du, Jin-Hui Hu, Li Kuang

“…Actual self-harm rates were 4.7% (lifetime), 1.64% (past year), and 0.37% (past month). …”
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A retrospective analysis of 6942 amniocentesis cases by Qingsha An, Yuxiao Huang, Feifei Yu, Yilun Tao, Juan Li, Xiaoze Li

“…The analysis encompassed the detection rate of chromosomal abnormalities via amniocentesis, the proportion and positive predictive value (PPV) of each indication group, the distribution of maternal age and gestational age, and the characteristic patterns of confirmed diagnostic findings. …”
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Mannheim Peritoneal Index in the Prediction of Postoperative Complications in Patients with Peritonitis by N. N. Aksenova, F. R. Akhmerov, M. V. Maleyev

“…In patients with local postoperative complications being developed, the MPI values were higher (p&lt;0.05) than in those without them. The mortality rates that have been predicted by means of MPI (16.3%) and actual (15.2%) are actually in agreement. …”
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Amazon Rainforest Exchange of Carbon and Subcanopy Air Flow: Manaus LBA Site—A Complex Terrain Condition by Julio Tóta, David Roy Fitzjarrald, Maria A. F. da Silva Dias

“…We tested the hypothesis that horizontal drainage flow over this study area is significant and can affect the interpretation of the high carbon uptake rates reported by previous works at this site. A similar experimental design as the one by Tóta et al. (2008) was used with a network of wind, air temperature, and CO2 sensors above and below the forest canopy. …”
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Adaptive Quantum-Inspired Evolution for Denoising PCG Signals in Unseen Noise Conditions by Lubna Siddiqui, Ashish Mani, Jaspal Singh

“…The filter coefficients were optimised using the proposed QiEA with Adaptive Rotation Gate Operator (ARGO). The proposed algorithm accelerates convergence towards optimal solutions based on fitness feedback, improving filter optimisation while clamping rotation angles to maintain algorithm stability. …”
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Evaluation of Artesunate-mefloquine as a Novel Alternative Treatment for Schistosomiasis in African Children (SchistoSAM): protocol of a proof-of-concept, open-label, two-arm, indi... by Emmanuel Bottieau, Achilleas Tsoumanis, Yven Van Herrewege, Diana Arango, Christophe Burm, Badara Cisse, Souleymane Mboup, Clémentine Roucher, Isabel Brosius, Moustapha Mbow, Babacar Thiendella Faye, Annelies De Hondt, Bart Smekens, Linda Paredis, Idzi Potters, Katja Polman

“…The trial’s primary endpoints are the efficacy (cure rate (CR), assessed by microscopy) and safety (frequency and pattern of drug-related adverse events) of one AM course versus PZQ at 4 weeks after treatment. …”
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Feasibility Assessment of an Optically Powered Digital Retinal Prosthesis Architecture for Retinal Ganglion Cell Stimulation by William Lemaire, Maher Benhouria, Konin Koua, Wei Tong, Gabriel Martin-Hardy, Melanie Stamp, Kumaravelu Ganesan, Louis-Philippe Gauthier, Marwan Besrour, Arman Ahnood, David John Garrett, Sebastien Roy, Michael R. Ibbotson, Steven Prawer, Rejean Fontaine

“…This confirms the feasibility of generating a response in RGCs with an infrared-powered digital architecture capable of delivering complex sequential stimulation patterns at high repetition rates, albeit with some limitations.…”
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Spatiotemporal Change in Climate Variables and Resources of Wind， Solar Radiation and Precipitation in Qinghai Province from 1961 to 2021 by Meixia DUAN, Miaoni GAO, Han JIANG, Runhong XU, buda SU, Tong JIANG

“…In order to evaluate the potential of wind， solar radiation and precipitation in guaranteeing the development of clean energy comprehensively， this study analyzed the temporal and spatial changes in climate variables and resources of wind speed， solar radiation and precipitation in Qinghai Province throughout the year and four seasons from 1961 to 2021 based on the observation data of daily 10-meter-height wind speed， sunshine duration and precipitation at 51 meteorological stations.The results are as follows： （1） The annual average wind speed， solar radiation and precipitation in Qinghai Province are 2.67 m·s-1， 6084.2 MJ·m-2， and 299.7 mm， respectively.Wind speed tends to be higher in the western regions and lower in the east， which exceeds 3 m/s and reaches the standard for wind energy resource development in western Qinghai.The annual solar radiation in the entire Province exceeds 5040 MJ·m-2， and reaches the "very rich" level according to China Solar energy GB Standards.The solar radiation of Qaidam Basin is at its highest abundance level， which is ideal for solar energy resource development.Precipitation generally decreases from southeast to northwest.The resources of wind， solar radiation， and precipitation in Qinghai Province exhibits seasonal complementarity， characterized by a pattern of “strong winds， good sunlight， and less water in spring， whereas weak winds， good sunlight， and abundant water in summer”.（2） Under climate change， the annual average wind speed and total solar radiation in Qinghai Province show a significant decrease at rates of 0.16 m·s-1·10a-1and 29.04 MJ·m-2·（10a）-1， respectively.The western and central parts of Haixi are most affected by these changes， but the wind speed and solar radiation still remain within the acceptable range for wind energy and photovoltaic resource development.Meanwhile， precipitation increases significantly at a rate of 8.85 mm·（10a）-1， with the largest increase observed in western Yushu， eastern Haixi and northern Guoluo.The most significant decrease in wind speed is observed in spring， while summer solar radiation decreases at the fastest rate but with a substantial increase in precipitation.The changes in solar radiation and precipitation could be ascribed to the increased cloud cover in this region.（3） The changes in the areas where wind speed and solar radiation meet suitable development standards in Qinghai Province are not significant with reduced variabilities， which could ensure the stable development of clean energy.Wind energy resources in western Qinghai （such as Tanggula Mountains）， solar energy resources in the Qaidam Basin， and water energy resources in the three major river basins of the Yangtze River， Yellow River， and Lancang River have great potential for development.Overall， the results provide a theoretical foundation for the development of a balanced clean energy system encompassing wind， solar and hydropower.This contributes to achieving national "dual carbon" goals and enhancing the high-quality development of Qinghai Province.…”
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Hydroformer: Frequency Domain Enhanced Multi‐Attention Transformer for Monthly Lake Level Reconstruction With Low Data Input Requirements by Minglei Hou, Jiahua Wei, Yang Shi, Shengling Hou, Wenqian Zhang, Jiaqi Xu, Yue Wu, He Wang

“…The model exhibited good performance even when training data missing rates were below 50%, particularly in lakes with significant seasonal fluctuations. …”
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Cross-national research on adolescent mental health: a systematic review comparing research in low, middle and high-income countries by Xiao Zhang, Anne Abio, David M Ndetei, Samir Kumar Praharaj, Wan Mohd Azam Wan Mohd Yunus, Yuko Mori, Zahra Kafami Khorasani, Sonja Gilbert, Meytal Grimland, Nikita Bezborodovs, Sanju Silwal, Minja Westerlund, Hitoshi Kaneko, Emmi Heinonen, Andre Sourander

“…It highlights the need to address methodological heterogeneity, including the use of validated and culturally adapted measures, comprehensive reporting of sampling procedures, sample sizes, response rates and greater attention to generalisability. …”
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